MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice

Journal of Clinical Investigation

Volumn 121, Issue 11, 2011, Pages 4383-4392

  Zou, Weiguo ^a   Greenblatt, Matthew B ^a   Shim, Jae Hyuck ^a   Kant, Shashi ^b   Zhai, Bo ^c   Lotinun, Sutada ^d   Brady, Nicholas ^a   Hu, Dorothy Zhang ^a   Gygi, Steven P ^c   Baron, Roland ^d   Davis, Roger J ^b   Jones, Dallas ^a   Glimcher, Laurie H ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MIXED LINEAGE KINASE 3; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR RUNX2;

ARTICLE; BONE DEFECT; BONE DEVELOPMENT; BONE MINERALIZATION; CELL DIFFERENTIATION; FACIOGENITAL DYSPLASIA; FGD1 GENE; GENE; GENE MUTATION; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; BONE DEVELOPMENT; CDC42 GTP-BINDING PROTEIN; DISEASE MODELS, ANIMAL; DWARFISM; ENZYME ACTIVATION; FACE; FEMALE; GENE KNOCK-IN TECHNIQUES; GENETIC DISEASES, X-LINKED; GENITALIA, MALE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HAND DEFORMITIES, CONGENITAL; HEART DEFECTS, CONGENITAL; HUMANS; MALE; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MUTATION; OSTEOBLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEINS;

EID: 80555136829     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI59041     Document Type: Article

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