Molecular and mechano-biology of collagen gel contraction mediated by human MG-63 cells: Involvement of specific intracellular signaling pathways and the cytoskeleton

Biochemistry and Cell Biology

Volumn 87, Issue 6, 2009, Pages 895-904

  Parreno, Justin ^a   Hart, David A ^b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Collagen gel contraction; Mechanical loading; Mechanotransduction; Osteoblast

Indexed keywords

COLLAGEN GELS; CYTOSKELETAL; CYTOSKELETONS; DEPOLYMERIZATION AGENTS; GEL CONTRACTION; HIGH CONCENTRATION; HUMAN OSTEOBLAST LIKES; INTEGRINS; INTRACELLULAR SIGNALING PATHWAYS; INTRINSIC STRESS; LOW CONCENTRATIONS; MECHANICAL LOADING; MECHANO-BIOLOGY; MECHANOTRANSDUCTION; MICROTUBULES; MRNA LEVEL; NOCODAZOLE; PROTEIN KINASE INHIBITORS; REAL-TIME PCR; SIGNALING PATHWAYS; TIME POINTS;

CELL CULTURE; COLLAGEN; GENE EXPRESSION; RNA; SIGNALING; TISSUE; ULSI CIRCUITS;

GELS;

ALPHA2 INTEGRIN; COLLAGEN GEL; INTERSTITIAL COLLAGENASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; RHO KINASE; STROMELYSIN;

ARTICLE; BONE REMODELING; CELL CULTURE; CELL LINE; CYTOSKELETON; DEPOLYMERIZATION; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MICROTUBULE; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

CELL LINE, TUMOR; COLLAGEN; CYTOSKELETON; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GELS; HUMANS; INTEGRIN ALPHA2; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 3; MICROTUBULES; NOCODAZOLE; OSTEOSARCOMA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RHO-ASSOCIATED KINASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUBULIN MODULATORS;

EID: 74549144553     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/O09-052     Document Type: Article

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