Hypoxia induces osteogenic/angiogenic responses of bone marrow-derived mesenchymal stromal cells seeded on bone-derived scaffolds via ERK1/2 and p38 pathways

Biotechnology and Bioengineering

Volumn 110, Issue 6, 2013, Pages 1794-1804

  Zhou, Yi ^a,b   Guan, Xiaoxu ^a   Wang, Huiming ^a   Zhu, Zhuoli ^b   Li, Chiquan ^c   Wu, Shu ^c   Yu, Haiyang ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c Beijing Dede Chuangye Technology Company Limited   (China)

Author keywords

Angiogenesis; BMSCs; Bone derived scaffolds; ERK1 2; Hypoxia; Osteogenesis; P38

Indexed keywords

ANGIOGENESIS; BMSCS; ERK1/2; HYPOXIA; OSTEOGENESIS; P38;

BONE; PHOSPHATASES; REPAIR; TISSUE;

SCAFFOLDS (BIOLOGY);

ALKALINE PHOSPHATASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OSTEOCALCIN; SYNAPTOPHYSIN; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; BONE DEFECT; BONE DEVELOPMENT; BONE MARROW DERIVED MESENCHYMAL STROMAL CELL; BONE TISSUE; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE EXPRESSION; HUMAN; HYPOXIA; IN VIVO STUDY; MESENCHYMAL STROMA CELL; NONHUMAN; PROTEIN EXPRESSION; RAT; TISSUE ENGINEERING;

ANALYSIS OF VARIANCE; ANIMALS; CELL HYPOXIA; CELL PROLIFERATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MAP KINASE SIGNALING SYSTEM; MESENCHYMAL STROMAL CELLS; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOGENESIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84876746211     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24827     Document Type: Article

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