Cold exposure stimulates lipid metabolism, induces inflammatory response in the adipose tissue of mice and promotes the osteogenic differentiation of BMMSCs via the p38 MAPK pathway in vitro

International Journal of Clinical and Experimental Pathology

Volumn 8, Issue 9, 2015, Pages 10875-10886

  Nie, Yizhen ^a   Yan, Zhaoqi ^a   Yan, Wei ^a   Xia, Qingyan ^b   Zhang, Yina ^a  

^a THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b The Fourth Clinical Hospital of Harbin Medical University   (China)

Author keywords

Adipose tissue; BMMSCs; Cold exposure; Lipolysis; Osteogenic differentiation; P38 MAPK signalling pathway; WAT browning

Indexed keywords

AUTACOID; CYCLIC AMP; CYTOKINE; FATTY ACID; GLYCEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE INHIBITOR; TRIACYLGLYCEROL;

ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; BONE DEVELOPMENT; BROWN ADIPOSE TISSUE; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; COLD; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; LIPOLYSIS; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; PHENOTYPE; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TIME FACTOR; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE, BROWN; ADIPOSE TISSUE, WHITE; ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CHOLESTEROL, HDL; CHOLESTEROL, LDL; COLD TEMPERATURE; CYCLIC AMP; CYTOKINES; ENZYME ACTIVATION; FATTY ACIDS, NONESTERIFIED; GLYCEROL; INFLAMMATION MEDIATORS; LIPIDS; LIPOLYSIS; MESENCHYMAL STROMAL CELLS; MICE, INBRED C57BL; OSTEOGENESIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION; TIME FACTORS; TRIGLYCERIDES;

EID: 85013041894     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

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