p38MAP Kinase activity is required for human primary adipocyte differentiation

FEBS Letters

Volumn 581, Issue 29, 2007, Pages 5591-5596

  Aouadi, M ^a,b   Jager, J ^a,b   Laurent, K ^a,b   Gonzalez, T ^a,b   Cormont, M ^a,b   Binetruy B ^a,c   Le Marchand Brustel, Y ^a,b,d   Tanti, J F ^a,b   Bost, F ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

^d UNIVERSITY HOSPITAL OF NICE   (France)

Author keywords

Adipogenesis; C EBPbeta; Human preadipocytes; p38MAPK; PPAR ; Subcutaneous adipose tissue; Visceral adipose tissue

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRIACYLGLYCEROL;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE TISSUE; ARTICLE; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL PROLIFERATION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ADIPOCYTES; ADIPOGENESIS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL CYCLE; CELL DIFFERENTIATION; HUMANS; IMIDAZOLES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PPAR GAMMA; SIGNAL TRANSDUCTION; THREONINE;

EID: 36549069731     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.10.064     Document Type: Article

References (19)

1. Pearson G., Robinson F., Beers Gibson T., Xu B.E., Karandikar M., Berman K., and Cobb M.H. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr. Rev. 22 (2001) 153-183
2. Aouadi M., Binetruy B., Caron L., Le Marchand-Brustel Y., and Bost F. Role of MAPKs in development and differentiation: lessons from knockout mice. Biochimie 88 (2006) 1091-1098 [Epub 2006 June 27]
3. Bost F., Aouadi M., Caron L., and Binetruy B. The role of MAPKs in adipocyte differentiation and obesity. Biochimie 87 (2005) 51-56
4. Bost F., Caron L., Marchetti I., Dani C., Le Marchand-Brustel Y., and Binetruy B. Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage. Biochem. J. 361 (2002) 621-627
5. Bost F., et al. The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis. Diabetes 54 (2005) 402-411
6. Engelman J.A., Berg A.H., Lewis R.Y., Lin A., Lisanti M.P., and Scherer P.E. Constitutively active mitogen-activated protein kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis. J. Biol. Chem. 274 (1999) 35630-35638
7. Engelman J.A., Lisanti M.P., and Scherer P.E. Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis. J. Biol. Chem. 273 (1998) 32111-32120
8. Batchvarova N., Wang X.Z., and Ron D. Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153). Embo J. 14 (1995) 4654-4661
9. Yang T.T., Xiong Q., Enslen H., Davis R.J., and Chow C.W. Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases. Mol. Cell Biol. 22 (2002) 3892-3904
10. Ho I.C., Kim J.H., Rooney J.W., Spiegelman B.M., and Glimcher L.H. A potential role for the nuclear factor of activated T cells family of transcriptional regulatory proteins in adipogenesis. Proc. Natl. Acad. Sci. USA 95 (1998) 15537-15541
11. Aouadi M., Laurent K., Prot M., Le Marchand-Brustel Y., Binetruy B., and Bost F. Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages. Diabetes 55 (2006) 281-289
12. Gomez-Ambrosi J., et al. Gene expression profile of omental adipose tissue in human obesity. Faseb J. 18 (2004) 215-217 [Epub 2003 November 20]
13. Kim G.Y., Mercer S.E., Ewton D.Z., Yan Z., Jin K., and Friedman E. The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation. J. Biol. Chem. 277 (2002) 29792-29802 [Epub 2002 June 10]
14. Newell F.S., Su H., Tornqvist H., Whitehead J.P., Prins J.B., and Hutley L.J. Characterization of the transcriptional and functional effects of fibroblast growth factor-1 on human preadipocyte differentiation. Faseb J. 20 (2006) 2615-2617 [Epub 2006 October 26]
15. Park B.H., Qiang L., and Farmer S.R. Phosphorylation of C/EBPbeta at a consensus extracellular signal-regulated kinase/glycogen synthase kinase 3 site is required for the induction of adiponectin gene expression during the differentiation of mouse fibroblasts into adipocytes. Mol. Cell Biol. 24 (2004) 8671-8680
16. Patel N.G., Holder J.C., Smith S.A., Kumar S., and Eggo M.C. Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation. Diabetes 52 (2003) 43-50
17. Zhang J.W., Tang Q.Q., Vinson C., and Lane M.D. Dominant-negative C/EBP disrupts mitotic clonal expansion and differentiation of 3T3-L1 preadipocytes. Proc. Natl. Acad. Sci. USA 101 (2004) 43-47 [Epub 2003 December 19]
18. Piwien-Pilipuk G., MacDougald O., and Schwartz J. Dual regulation of phosphorylation and dephosphorylation of C/EBPbeta modulate its transcriptional activation and DNA binding in response to growth hormone. J. Biol. Chem. 277 (2002) 44557-44565 [Epub 2002 September 3]
19. Tang Q.Q., Otto T.C., and Lane M.D. Mitotic clonal expansion: a synchronous process required for adipogenesis. Proc. Natl. Acad. Sci. USA 100 (2003) 44-49 [Epub 2002 December 26]