Affinity purification in target identification: the specificity challenge

Archives of Pharmacal Research

Volumn 38, Issue 9, 2015, Pages 1661-1685

  Zheng, Wenlu ^a   Li, Gang ^b   Li, Xiaoyu ^a,b  

^a PEKING UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Affinity purification; Phenotypic screening; Protein ligand interaction; Small molecule; Specificity; Target identification

Indexed keywords

PROTEOME; SODIUM CHLORIDE; AFFINITY LABELING; MOLECULAR PROBE; PROTEIN BINDING;

AFFINITY LABELING; AFFINITY PURIFICATION; ARTICLE; BINDING AFFINITY; CROSS LINKING; NOISE REDUCTION; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN TARGETING; PROTEOMICS; TWO DIMENSIONAL GEL ELECTROPHORESIS; ANIMAL; CHEMISTRY; DRUG DELIVERY SYSTEM; GENETICS; HUMAN; METABOLISM; MOLECULAR PROBE; PHENOTYPE; PHYSIOLOGY; PROCEDURES;

AFFINITY LABELS; ANIMALS; DRUG DELIVERY SYSTEMS; HUMANS; MOLECULAR PROBES; PHENOTYPE; PROTEIN BINDING; PROTEOME;

EID: 84942193082     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-015-0635-2     Document Type: Article

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