Triple bioorthogonal ligation strategy for simultaneous labeling of multiple enzymatic activities

Angewandte Chemie - International Edition

Volumn 51, Issue 18, 2012, Pages 4431-4434

  Willems, Lianne I ^a   Li, Nan ^a   Florea, Bogdan I ^a   Ruben, Mark ^a   Van Der Marel, Gijsbert A ^a   Overkleeft, Herman S ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

activity based profiling; bioorthogonal reactions; click chemistry; cycloadditions; tetrazines

Indexed keywords

ACTIVITY-BASED; BIOORTHOGONAL REACTIONS; CLICK CHEMISTRY; CYCLOADDITIONS; TETRAZINES;

CATALYSIS; CHEMISTRY;

CYCLOADDITION;

(2.2.1)BICYCLOHEPT 2 ENE; (2.2.1)BICYCLOHEPT-2-ENE; BICYCLO COMPOUND; COPPER; HEPTANE; PROTEASOME; SINGLE HETEROCYCLIC RINGS; TETRAZOLE DERIVATIVE;

ARTICLE; CATALYSIS; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; CLICK CHEMISTRY; CYCLIZATION; HUMAN; STAINING;

BICYCLO COMPOUNDS; CATALYSIS; CELL LINE; CLICK CHEMISTRY; COPPER; CYCLIZATION; HEPTANES; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; MOLECULAR STRUCTURE; PROTEASOME ENDOPEPTIDASE COMPLEX; STAINING AND LABELING; TETRAZOLES;

EID: 84860187002     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201200923     Document Type: Article

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