Natural products reveal cancer cell dependence on oxysterol-binding proteins

Nature Chemical Biology

Volumn 7, Issue 9, 2011, Pages 639-647

  Burgett, Anthony W G ^a   Poulsen, Thomas B ^a   Wangkanont, Kittikhun ^a   Anderson, D Ryan ^a   Kikuchi, Chikako ^a   Shimada, Kousei ^a   Okubo, Shuichi ^a   Fortner, Kevin C ^a   Mimaki, Yoshihiro ^b   Kuroda, Minpei ^b   Murphy, Jason P ^c   Schwalb, David J ^c   Petrella, Eugene C ^c   Cornella Taracido, Ivan ^c   Schirle, Markus ^c   Tallarico, John A ^c   Shair, Matthew D ^a  

^a HARVARD UNIVERSITY   (United States)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^c NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYCHOLESTEROL; BINDING PROTEIN; CEPHALOSTATIN 1; NATURAL PRODUCT; OSW 1; OXYSTEROL BINDING PROTEIN; OXYSTEROL BINDING PROTEIN RELATED 4L; RITTERAZINE B; SCHWEINFURTHIN A; SHORT HAIRPIN RNA; STELLETTIN; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ARTICLE; CANCER CELL; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; HUMAN; HUMAN CELL; LIPID METABOLISM; LIPID TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

EID: 84860389725     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.625     Document Type: Article

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