Aminopeptidase N/CD13 induces angiogenesis through interaction with a pro-angiogenic protein, galectin-3

Biochemical and Biophysical Research Communications

Volumn 363, Issue 2, 2007, Pages 336-341

  Yang, Eunju ^a   Shim, Joong Sup ^a   Woo, Hee Jong ^b   Kim, Kyu Won ^c   Kwon, Ho Jeong ^a  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

^c Tumor Microenvironment Global Core Research Center   (South Korea)

Author keywords

Aminopeptidase N; Angiogenesis; Galectin 3; Protein protein interaction

Indexed keywords

ANGIOGENIC PROTEIN; CARBOHYDRATE; COMPLEMENTARY DNA; GALACTOSIDE; GALECTIN 3; LECTIN; MICROSOMAL AMINOPEPTIDASE;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL SURFACE; CONTROLLED STUDY; DNA LIBRARY; EMBRYO; ENDOTHELIUM CELL; FOREBRAIN; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ANGIOGENIC PROTEINS; ANTIGENS, CD13; CELLS, CULTURED; ENDOTHELIAL CELLS; GALECTIN 3; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN INTERACTION MAPPING;

EID: 34748837860     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.08.179     Document Type: Article

References (22)

1. Luciani N., Marie-Claire C., Ruffet E., Beaumont A., Roques B.P., and Fournie-Zaluski M.C. Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action. Biochemistry 37 (1998) 686-692
2. Lo Coco F., Pasqualetti D., Lopez M., Panzini E., Gentile A., Latagliata R., Monarca B., and De Rossi G. Immunophenotyping of acute myeloid leukaemia: relevance of analysing different lineage-associated markers. Blut 58 (1989) 235-240
3. Look A.T., Ashmun R.A., Shapiro L.H., and Peiper S.C. Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J. Clin. Invest. 83 (1989) 1299-1307
4. Pasqualini R., Koivunen E., Kain R., Lahdenranta J., Sakamoto M., Stryhn A., Ashmun R.A., Shapiro L.H., Arap W., and Ruoslahti E. Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis. Cancer Res. 60 (2000) 722-727
5. Shim J.S., Kim J.H., Cho H.Y., Yum Y.N., Kim S.H., Park H.J., Shim B.S., Choi S.H., and Kwon H.J. Irreversible inhibition of CD13/aminopeptidase N by the antiangiogenic agent curcumin. Chem. Biol. 10 (2003) 695-704
6. Bhagwat S.V., Lahdenranta J., Giordano R., Arap W., Pasqualini R., and Shapiro L.H. CD13/APN is activated by angiogenic signals and is essential for capillary tube formation. Blood 97 (2001) 652-659
7. Nguyen M., Eilber F.R., and Defrees S. Novel synthetic analogs of sialyl Lewis X can inhibit angiogenesis in vitro and in vivo. Biochem. Biophys. Res. Commun. 228 (1996) 716-723
8. Nangia-Makker P., Baccarini S., and Raz A. Carbohydrate-recognition and angiogenesis. Cancer Metastasis Rev. 19 (2000) 51-57
9. Dumic J., Dabelic S., and Flogel M. Galectin-3: an open-ended story. Biochim. Biophys. Acta 1760 (2006) 616-635
10. Akahani S., Nangia-Makker P., Inohara H., Kim H.R., and Raz A. Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family. Cancer Res. 57 (1997) 5272-5276
11. Ochieng J., Furtak V., and Lukyanov P. Extracellular functions of galectin-3. Glycoconj. J. 19 (2004) 527-535
12. Yu F., Finley Jr. R.L., Raz A., and Kim H.R. Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation. J. Biol. Chem. 277 (2002) 15819-15827
13. Fukumori T., Takenaka Y., Yoshii T., Kim H.R., Hogan V., Inohara H., Kagawa S., and Raz A. CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis. Cancer Res. 63 (2003) 8302-8311
14. Nangia-Makker P., Honjo Y., Sarvis R., Akahani S., Hogan V., Pienta K.J., and Raz A. Galectin-3 induces endothelial cell morphogenesis and angiogenesis. Am. J. Pathol. 156 (2000) 899-909
15. Shim J.S., Lee J., Park H.J., Park S.J., and Kwon H.J. A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function. Chem. Biol. 11 (2004) 1455-1463
16. Kim B.G., and Woo H.J. Expression and characterization of the recombinant human galectin-3. Kor. J. Vet. Res. 37 (1997) 547-554
17. O'Connell P.J., Gerkis V., and d'Apice A.J. Variable O-glycosylation of CD13 (aminopeptidase N). J. Biol. Chem. 266 (1991) 4593-4597
18. Robertson P.L., Du Bois M., Bowman P.D., and Goldstein G.W. Angiogenesis in developing rat brain: an in vivo and in vitro study. Brain Res. 355 (1985) 219-223
19. Knight P.J., Crickmore N., and Ellar D.J. The receptor for Bacillus thuringiensis CrylA(c) delta-endotoxin in the brush border membrane of the lepidopteran Manduca sexta is aminopeptidase N. Mol. Microbiol. 11 (1994) 429-436
20. Godet M., Grosclaude J., Delmas B., and Laude H. Major receptor-binding and neutralization determinants are located within the same domain of the transmissible gastroenteritis virus (coronavirus) spike protein. J. Virol. 68 (1994) 8008-8016
21. Luan Y., and Xu W. The structure and main functions of aminopeptidase N. Curr. Med. Chem. 14 (2007) 639-647
22. Mina-Osorio P., Soto-Cruz I., and Ortega E. A role for galectin-3 in CD13-mediated homotypic aggregation of monocytes. Biochem. Biophys. Res. Commun. 353 (2007) 605-610