HIF-1α suppressing small molecule, LW6, inhibits cancer cell growth by binding to calcineurin b homologous protein 1

Biochemical and Biophysical Research Communications

Volumn 458, Issue 1, 2015, Pages 14-20

  Kim, Beom Seok ^a   Lee, Kyeong ^b   Jung, Hye Jin ^c   Bhattarai, Deepak ^b   Kwon, Ho Jeong ^a,d  

^a Yonsei University   (South Korea)

^b Dongguk University   (South Korea)

^c SunMoon University   (South Korea)

^d Yonsei University College of Medicine   (South Korea)

Author keywords

Angiogenesis; Calcineurin b homologous protein 1; Hypoxia inducible factor 1 ; LW6; Target identification

Indexed keywords

ANTINEOPLASTIC AGENT; CALCINEURIN; CALCINEURIN B HOMOLOGOUS PROTEIN 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LW 6; UNCLASSIFIED DRUG; ACETANILIDE DERIVATIVE; ADAMANTANE; ANGIOGENESIS INHIBITOR; CALCIUM; CALCIUM BINDING PROTEIN; CHP1 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN;

ANGIOGENESIS; ARTICLE; CANCER GROWTH; CLICK CHEMISTRY; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEOMICS; AMINO ACID SEQUENCE; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CELL SURFACE DISPLAY; DRUG EFFECTS; GENE SILENCING; GENETICS; HEPG2 CELL LINE; METABOLISM; MOLECULAR DOCKING; MOLECULAR GENETICS; MOLECULARLY TARGETED THERAPY; NEOVASCULARIZATION, PATHOLOGIC; PROCEDURES; UMBILICAL VEIN ENDOTHELIAL CELL;

ACETANILIDES; ADAMANTANE; AMINO ACID SEQUENCE; ANGIOGENESIS INHIBITORS; CALCIUM; CALCIUM-BINDING PROTEINS; CELL SURFACE DISPLAY TECHNIQUES; CLICK CHEMISTRY; GENE KNOCKDOWN TECHNIQUES; HEP G2 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; MOLECULAR TARGETED THERAPY; NEOVASCULARIZATION, PATHOLOGIC;

EID: 84922917268     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.01.031     Document Type: Article

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