A small molecule inhibitor of β-catenin/cyclic AMP response element-binding protein transcription

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 34, 2004, Pages 12682-12687

  Emami, Katayoon H ^a   Nguyen, Cu ^a   Ma, Hong ^a   Kim, Dae Hoon ^a   Jeong, Kwang Won ^a   Eguchi, Masakatsu ^a,b   Moon, Randall T ^b,c   Teo, Jia Ling ^a   Oh, Se Wong ^d   Kim, Hak Yeop ^d   Moon, Sung Hwan ^d   Hall, Jong Ryul ^d   Kahn, Michael ^a,b  

^a Institute for Chemical Genomics   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d Choongwae Pharma Co   (South Korea)

Author keywords

Coactivators; T cell factor; Wnt pathway

Indexed keywords

BETA CATENIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ICG 001; PROTEIN INHIBITOR; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CARCINOMA CELL; COLON CANCER; COLON CARCINOMA; COLON POLYPOSIS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; GENE ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE CELL; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN BINDING; SOMATIC MUTATION; XENOGRAFT;

ADENOMATOUS POLYPOSIS COLI; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BETA CATENIN; BICYCLO COMPOUNDS, HETEROCYCLIC; CELL LINE; COLON; COLONIC NEOPLASMS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIN D1; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; LYMPHOID ENHANCER-BINDING FACTOR 1; MALE; MICE; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS; MOLECULAR STRUCTURE; NEOPLASM PROTEINS; PYRIMIDINONES; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA; EUKARYOTA; MUS MUSCULUS;

EID: 4344587136     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0404875101     Document Type: Article

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