Activity-based protein profiling: From enzyme chemistry to proteomic chemistry

Annual Review of Biochemistry

Volumn 77, Issue , 2008, Pages 383-414

  Cravatt, Benjamin F ^a   Wright, Aaron T ^a   Kozarich, John W ^b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b ACTIVX BIOSCIENCES INC   (United States)

Author keywords

Affinity label; Mass spectrometry; Proteomics

Indexed keywords

5' (4 FLUOROSULFONYLBENZOYL)ADENOSINE; ADENOSINE TRIPHOSPHATE; CASPASE; CYSTEINE PROTEINASE; CYTOCHROME P450; EPOXIDE; FLUORESCENT DYE; GLYCOSIDASE; HISTONE DEACETYLASE INHIBITOR; HYDROLASE; HYPOTHEMYCIN; ILOMASTAT; MARIMASTAT; MATRIX METALLOPROTEINASE INHIBITOR; METALLOHYDROLASE; NUCLEOTIDE BINDING PROTEIN; PAPAIN; PHOSPHATASE; PHOSPHONIC ACID DERIVATIVE; PHOSPHOTRANSFERASE; POLYKETIDE; PROTEOME; SERINE DEHYDRATASE; UBIQUITIN; UNCLASSIFIED DRUG; VORINOSTAT; WORTMANNIN; PROTEIN;

AFFINITY LABELING; ANGIOGENESIS; CAPILLARY ELECTROPHORESIS; CELL INVASION; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME CHEMISTRY; FLUORESCENCE ANALYSIS; GEL ELECTROPHORESIS; IMMUNOCOMPETENT CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICHAEL ADDITION; NATURAL KILLER CELL; PANCREAS CANCER; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEOMICS; REVIEW; TUMOR GROWTH; ANIMAL; BIOCHEMISTRY; BIOLOGICAL MODEL; CHEMICAL MODEL; CHEMISTRY; GENOME; HUMAN; METHODOLOGY;

EUKARYOTA; PROKARYOTA;

ADENOSINE TRIPHOSPHATE; ANIMALS; BIOCHEMISTRY; CHROMATOGRAPHY, LIQUID; CYSTEINE ENDOPEPTIDASES; GENOME; HUMANS; HYDROLASES; MASS SPECTROMETRY; MODELS, BIOLOGICAL; MODELS, CHEMICAL; PROTEINS; PROTEOME; PROTEOMICS;

EID: 50649112213     PISSN: 00664154     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.biochem.75.101304.124125     Document Type: Review

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