Target identification using drug affinity responsive target stability (DARTS)

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 51, 2009, Pages 21984-21989

  Lomenick, Brett ^a   Hao, Rui ^a   Jonai, Nao ^a   Chin, Randall M ^a   Aghajan, Mariam ^a   Warburton, Sarah ^a   Wang, Jianing ^a   Wu, Raymond P ^a   Gomez, Fernando ^b   Loo, Joseph A ^a,b   Wohlschlegel, James A ^a   Vondriska, Thomas M ^a   Pelletier, Jerry ^c   Herschman, Harvey R ^a   Clardy, Jon ^d   Clarke, Catherine F ^b   Huang, Jing ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MCGILL UNIVERSITY   (Canada)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Aging; Label free; Proteomics; Small molecules

Indexed keywords

CELECOXIB; COMPLEMENTARY DNA; PROTEINASE; RAPAMYCIN; RESVERATROL; TACROLIMUS;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG AFFINITY RESPONSIVE TARGET STABILITY; DRUG BINDING; DRUG MECHANISM; DRUG SCREENING; HUMAN; HUMAN CELL; LONGEVITY; MOLECULAR IMAGING; NONHUMAN; PLANT PRODUCT; PRIORITY JOURNAL; PROTEIN INTERACTION; TRANSLATION INITIATION;

EUKARYOTA;

EID: 76049084586     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0910040106     Document Type: Article

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