p42/p44 MAPKs are intracellular targets of the CDK inhibitor purvalanol

Oncogene

Volumn 21, Issue 42, 2002, Pages 6413-6424

  Knockaert, Marie ^a   Lenormand, Philippe ^b   Gray, Nathanael ^c   Schultz, Peter ^c   Pouysségur, Jacques ^b   Meijer, Laurent ^a  

^a STATION BIOLOGIQUE   (France)

^b CENTRE ANTOINE LACASSAGNE   (France)

^c Novartis Institute for Functional Genomics   (United States)

Author keywords

CDKs; Erk; Inhibitors; Kinases; MAPK; Purvalanol

Indexed keywords

AMINOPURVALANOL; CASPASE; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; NG 97; PROTEIN P42; PROTEIN P44; PURINE DERIVATIVE; PURVALANOL; PURVALANOL A; PURVALANOL B; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL GROWTH; CELL PROLIFERATION; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOSE RESPONSE; DRUG POTENCY; DRUG PROTEIN BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VIVO STUDY; INTRACELLULAR KILLING; LUNG FIBROBLAST; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL;

ADENINE; ANIMALS; BLOTTING, WESTERN; CELL CYCLE; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; CRICETINAE; CYCLIN-DEPENDENT KINASES; ENZYME INHIBITORS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; LUCIFERASES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR STRUCTURE; PHOSPHOPROTEINS; PHOSPHORYLATION; RNA-BINDING PROTEINS; TRANSFECTION;

ANIMALIA; CERVUS ELAPHUS; CRICETINAE; CRICETULUS GRISEUS; MAMMALIA; MINK CELL FOCUS-FORMING VIRUS;

EID: 0037136718     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1205908     Document Type: Article

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