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Volumn 142, Issue , 2015, Pages 56-70

Myofibroblasts

Author keywords

Contraction; Contracture; Fibrosis; Inflammation; Scar; Stress fiber; Transforming growth factor beta; smooth muscle actin

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; F ACTIN; FIBROBLAST GROWTH FACTOR 2; FIBRONECTIN; GAMMA INTERFERON; HYALURONIC ACID; PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA3; VANILLOID RECEPTOR; VINCULIN; WNT PROTEIN; ACTIN; SIGNAL PEPTIDE;

EID: 84937828512     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2015.07.009     Document Type: Review
Times cited : (330)

References (379)
  • 1
    • 0001523484 scopus 로고
    • Wound contraction in relation to collagen formation in scorbutic guinea pigs
    • Abercrombie M., Flint M.H., James D.W. Wound contraction in relation to collagen formation in scorbutic guinea pigs. J. Embryol. Exp. Morphol. 1956, 4:167-175.
    • (1956) J. Embryol. Exp. Morphol. , vol.4 , pp. 167-175
    • Abercrombie, M.1    Flint, M.H.2    James, D.W.3
  • 7
    • 34249311647 scopus 로고    scopus 로고
    • Basic fibroblast growth factor in an artificial dermis promotes apoptosis and inhibits expression of alpha-smooth muscle actin, leading to reduction of wound contraction
    • Akasaka Y., Ono I., Tominaga A., Ishikawa Y., Ito K., Suzuki T., Imaizumi R., Ishiguro S., Jimbow K., Ishii T. Basic fibroblast growth factor in an artificial dermis promotes apoptosis and inhibits expression of alpha-smooth muscle actin, leading to reduction of wound contraction. Wound Repair Regen. 2007, 15:378-389.
    • (2007) Wound Repair Regen. , vol.15 , pp. 378-389
    • Akasaka, Y.1    Ono, I.2    Tominaga, A.3    Ishikawa, Y.4    Ito, K.5    Suzuki, T.6    Imaizumi, R.7    Ishiguro, S.8    Jimbow, K.9    Ishii, T.10
  • 9
    • 3242729348 scopus 로고    scopus 로고
    • Rho-mediated assembly of stress fibers is differentially regulated in corneal fibroblasts and myofibroblasts
    • Anderson S., DiCesare L., Tan I., Leung T., SundarRaj N. Rho-mediated assembly of stress fibers is differentially regulated in corneal fibroblasts and myofibroblasts. Exp. Cell Res. 2004, 298:574-583.
    • (2004) Exp. Cell Res. , vol.298 , pp. 574-583
    • Anderson, S.1    DiCesare, L.2    Tan, I.3    Leung, T.4    SundarRaj, N.5
  • 10
    • 2942653435 scopus 로고    scopus 로고
    • Integrin αVβ6-mediated activation of latent TGF-β requires the latent TGF-β binding protein-1
    • Annes J.P., Chen Y., Munger J.S., Rifkin D.B. Integrin αVβ6-mediated activation of latent TGF-β requires the latent TGF-β binding protein-1. J. Cell Biol. 2004, 165:723-734.
    • (2004) J. Cell Biol. , vol.165 , pp. 723-734
    • Annes, J.P.1    Chen, Y.2    Munger, J.S.3    Rifkin, D.B.4
  • 12
    • 75649103925 scopus 로고    scopus 로고
    • Future treatments in systemic sclerosis
    • Asano Y. Future treatments in systemic sclerosis. J. Dermatol. 2010, 37:54-70.
    • (2010) J. Dermatol. , vol.37 , pp. 54-70
    • Asano, Y.1
  • 13
    • 84883190661 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling induces IL-1beta expression by alveolar epithelial cells in pulmonary fibrosis
    • Aumiller V., Balsara N., Wilhelm J., Gunther A., Konigshoff M. Wnt/beta-catenin signaling induces IL-1beta expression by alveolar epithelial cells in pulmonary fibrosis. Am. J. Respir. Cell Mol. Biol. 2013, 49:96-104.
    • (2013) Am. J. Respir. Cell Mol. Biol. , vol.49 , pp. 96-104
    • Aumiller, V.1    Balsara, N.2    Wilhelm, J.3    Gunther, A.4    Konigshoff, M.5
  • 15
    • 84876119523 scopus 로고    scopus 로고
    • Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK
    • Baker A.M., Bird D., Lang G., Cox T.R., Erler J.T. Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK. Oncogene 2013, 32:1863-1868.
    • (2013) Oncogene , vol.32 , pp. 1863-1868
    • Baker, A.M.1    Bird, D.2    Lang, G.3    Cox, T.R.4    Erler, J.T.5
  • 17
    • 84961633325 scopus 로고    scopus 로고
    • The mechanical regulation of myofibroblasts; mechanically-guided matrix remodeling and prevention of fibrosis in regenerative medicine
    • Pan Staford Publishing Pte Ltd, Singapore, A.E.P.A.C.M. Cuerrier (Ed.)
    • Balestrini J., Hinz B. The mechanical regulation of myofibroblasts; mechanically-guided matrix remodeling and prevention of fibrosis in regenerative medicine. Cells, Forces and the Microenvironment 2014, Pan Staford Publishing Pte Ltd, Singapore. A.E.P.A.C.M. Cuerrier (Ed.).
    • (2014) Cells, Forces and the Microenvironment
    • Balestrini, J.1    Hinz, B.2
  • 23
    • 0024233056 scopus 로고
    • Correlation between the distribution of smooth muscle or non muscle myosins and alpha-smooth muscle actin in normal and pathological soft tissues
    • Benzonana G., Skalli O., Gabbiani G. Correlation between the distribution of smooth muscle or non muscle myosins and alpha-smooth muscle actin in normal and pathological soft tissues. Cell Motil. Cytoskelet. 1988, 11:260-274.
    • (1988) Cell Motil. Cytoskelet. , vol.11 , pp. 260-274
    • Benzonana, G.1    Skalli, O.2    Gabbiani, G.3
  • 25
    • 84893112406 scopus 로고    scopus 로고
    • Genome-wide transcriptional analysis of differentially expressed genes in diabetic, healing corneal epithelial cells: hyperglycemia-suppressed TGFbeta3 expression contributes to the delay of epithelial wound healing in diabetic corneas
    • Bettahi I., Sun H., Gao N., Wang F., Mi X., Chen W., Liu Z., Yu F.S. Genome-wide transcriptional analysis of differentially expressed genes in diabetic, healing corneal epithelial cells: hyperglycemia-suppressed TGFbeta3 expression contributes to the delay of epithelial wound healing in diabetic corneas. Diabetes 2014, 63:715-727.
    • (2014) Diabetes , vol.63 , pp. 715-727
    • Bettahi, I.1    Sun, H.2    Gao, N.3    Wang, F.4    Mi, X.5    Chen, W.6    Liu, Z.7    Yu, F.S.8
  • 32
    • 2942682928 scopus 로고    scopus 로고
    • Regulation of PDGF and its receptors in fibrotic diseases
    • Bonner J.C. Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev. 2004, 15:255-273.
    • (2004) Cytokine Growth Factor Rev. , vol.15 , pp. 255-273
    • Bonner, J.C.1
  • 35
    • 84886731169 scopus 로고    scopus 로고
    • Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease
    • Braitsch C.M., Kanisicak O., van Berlo J.H., Molkentin J.D., Yutzey K.E. Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease. J. Mol. Cell. Cardiol. 2013, 65:108-119.
    • (2013) J. Mol. Cell. Cardiol. , vol.65 , pp. 108-119
    • Braitsch, C.M.1    Kanisicak, O.2    van Berlo, J.H.3    Molkentin, J.D.4    Yutzey, K.E.5
  • 36
    • 79251479406 scopus 로고    scopus 로고
    • Wound macrophages as key regulators of repair: origin, phenotype, and function
    • Brancato S.K., Albina J.E. Wound macrophages as key regulators of repair: origin, phenotype, and function. Am. J. Pathol. 2011, 178:19-25.
    • (2011) Am. J. Pathol. , vol.178 , pp. 19-25
    • Brancato, S.K.1    Albina, J.E.2
  • 37
    • 77249143863 scopus 로고    scopus 로고
    • Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals
    • Brigstock D.R. Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals. J. Cell Commun. Signal 2010, 4:1-4.
    • (2010) J. Cell Commun. Signal , vol.4 , pp. 1-4
    • Brigstock, D.R.1
  • 44
    • 77951224978 scopus 로고    scopus 로고
    • The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation
    • Carracedo S., Lu N., Popova S.N., Jonsson R., Eckes B., Gullberg D. The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation. J. Biol. Chem. 2010, 285:10434-10445.
    • (2010) J. Biol. Chem. , vol.285 , pp. 10434-10445
    • Carracedo, S.1    Lu, N.2    Popova, S.N.3    Jonsson, R.4    Eckes, B.5    Gullberg, D.6
  • 45
    • 33744732429 scopus 로고    scopus 로고
    • Differential regulation of key stages in early corneal wound healing by TGF-beta isoforms and their inhibitors
    • Carrington L.M., Albon J., Anderson I., Kamma C., Boulton M. Differential regulation of key stages in early corneal wound healing by TGF-beta isoforms and their inhibitors. Investig. Ophthalmol. Vis. Sci. 2006, 47:1886-1894.
    • (2006) Investig. Ophthalmol. Vis. Sci. , vol.47 , pp. 1886-1894
    • Carrington, L.M.1    Albon, J.2    Anderson, I.3    Kamma, C.4    Boulton, M.5
  • 46
    • 72749102066 scopus 로고    scopus 로고
    • The role of integrins in corneal wound healing
    • Carter R.T. The role of integrins in corneal wound healing. Vet. Ophthalmol. 2009, 12(Suppl. 1):2-9.
    • (2009) Vet. Ophthalmol. , vol.12 , pp. 2-9
    • Carter, R.T.1
  • 47
    • 84902651454 scopus 로고    scopus 로고
    • Resolution mediator chemerin15 reprograms the wound microenvironment to promote repair and reduce scarring
    • Cash J.L., Bass M.D., Campbell J., Barnes M., Kubes P., Martin P. Resolution mediator chemerin15 reprograms the wound microenvironment to promote repair and reduce scarring. Curr. Biol. 2014, 24:1406-1414.
    • (2014) Curr. Biol. , vol.24 , pp. 1406-1414
    • Cash, J.L.1    Bass, M.D.2    Campbell, J.3    Barnes, M.4    Kubes, P.5    Martin, P.6
  • 48
    • 84927722050 scopus 로고    scopus 로고
    • Emerging cellular and molecular targets in fibrosis: implications for scleroderma pathogenesis and targeted therapy
    • Castelino F.V., Varga J. Emerging cellular and molecular targets in fibrosis: implications for scleroderma pathogenesis and targeted therapy. Curr. Opin. Rheumatol. 2014, 26:607-614.
    • (2014) Curr. Opin. Rheumatol. , vol.26 , pp. 607-614
    • Castelino, F.V.1    Varga, J.2
  • 50
    • 0028984528 scopus 로고
    • The specific NH2-terminal sequence Ac-EEED of alpha-smooth muscle actin plays a role in polymerization in vitro and in vivo
    • Chaponnier C., Goethals M., Janmey P.A., Gabbiani F., Gabbiani G., Vandekerckhove J. The specific NH2-terminal sequence Ac-EEED of alpha-smooth muscle actin plays a role in polymerization in vitro and in vivo. J. Cell Biol. 1995, 130:887-895.
    • (1995) J. Cell Biol. , vol.130 , pp. 887-895
    • Chaponnier, C.1    Goethals, M.2    Janmey, P.A.3    Gabbiani, F.4    Gabbiani, G.5    Vandekerckhove, J.6
  • 51
    • 67650451079 scopus 로고    scopus 로고
    • Dynamics of the expression of intermediate filaments vimentin and desmin during myofibroblast differentiation after corneal injury
    • Chaurasia S.S., Kaur H., de Medeiros F.W., Smith S.D., Wilson S.E. Dynamics of the expression of intermediate filaments vimentin and desmin during myofibroblast differentiation after corneal injury. Exp. Eye Res. 2009, 89:133-139.
    • (2009) Exp. Eye Res. , vol.89 , pp. 133-139
    • Chaurasia, S.S.1    Kaur, H.2    de Medeiros, F.W.3    Smith, S.D.4    Wilson, S.E.5
  • 52
    • 68349114970 scopus 로고    scopus 로고
    • Rho-mediated regulation of TGF-beta1- and FGF-2-induced activation of corneal stromal keratocytes
    • Chen J., Guerriero E., Sado Y., SundarRaj N. Rho-mediated regulation of TGF-beta1- and FGF-2-induced activation of corneal stromal keratocytes. Investig. Ophthalmol. Vis. Sci. 2009, 50:3662-3670.
    • (2009) Investig. Ophthalmol. Vis. Sci. , vol.50 , pp. 3662-3670
    • Chen, J.1    Guerriero, E.2    Sado, Y.3    SundarRaj, N.4
  • 53
    • 33947392959 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin expression enhances cell traction force
    • Chen J., Li H., SundarRaj N., Wang J.H. Alpha-smooth muscle actin expression enhances cell traction force. Cell Motil. Cytoskelet. 2007, 64:248-257.
    • (2007) Cell Motil. Cytoskelet. , vol.64 , pp. 248-257
    • Chen, J.1    Li, H.2    SundarRaj, N.3    Wang, J.H.4
  • 54
    • 84862832904 scopus 로고    scopus 로고
    • FGF-2- and TGF-beta1-induced downregulation of lumican and keratocan in activated corneal keratocytes by JNK signaling pathway
    • Chen J., Wong-Chong J., SundarRaj N. FGF-2- and TGF-beta1-induced downregulation of lumican and keratocan in activated corneal keratocytes by JNK signaling pathway. Investig. Ophthalmol. Vis. Sci. 2011, 52:8957-8964.
    • (2011) Investig. Ophthalmol. Vis. Sci. , vol.52 , pp. 8957-8964
    • Chen, J.1    Wong-Chong, J.2    SundarRaj, N.3
  • 55
    • 79952134815 scopus 로고    scopus 로고
    • Beta-catenin mediates mechanically regulated, transforming growth factor-beta1-induced myofibroblast differentiation of aortic valve interstitial cells
    • Chen J.H., Chen W.L., Sider K.L., Yip C.Y., Simmons C.A. beta-catenin mediates mechanically regulated, transforming growth factor-beta1-induced myofibroblast differentiation of aortic valve interstitial cells. Arterioscler. Thromb. Vasc. Biol. 2011, 31:590-597.
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , pp. 590-597
    • Chen, J.H.1    Chen, W.L.2    Sider, K.L.3    Yip, C.Y.4    Simmons, C.A.5
  • 56
    • 84900407266 scopus 로고    scopus 로고
    • The complex interplay between ERK1/2, TGFbeta/Smad, and Jagged/Notch signaling pathways in the regulation of epithelial-mesenchymal transition in retinal pigment epithelium cells
    • Chen X., Xiao W., Wang W., Luo L., Ye S., Liu Y. The complex interplay between ERK1/2, TGFbeta/Smad, and Jagged/Notch signaling pathways in the regulation of epithelial-mesenchymal transition in retinal pigment epithelium cells. PLoS One 2014, 9:e96365.
    • (2014) PLoS One , vol.9 , pp. e96365
    • Chen, X.1    Xiao, W.2    Wang, W.3    Luo, L.4    Ye, S.5    Liu, Y.6
  • 58
    • 61849141352 scopus 로고    scopus 로고
    • TGFbeta promotes Wnt expression during cataract development
    • Chong C.C., Stump R.J., Lovicu F.J., McAvoy J.W. TGFbeta promotes Wnt expression during cataract development. Exp. Eye Res. 2009, 88:307-313.
    • (2009) Exp. Eye Res. , vol.88 , pp. 307-313
    • Chong, C.C.1    Stump, R.J.2    Lovicu, F.J.3    McAvoy, J.W.4
  • 59
  • 61
    • 0019159203 scopus 로고
    • Ultrastructure of traction retinal detachment in rhesus monkey eyes after a posterior penetrating ocular injury
    • Cleary P.E., Minckler D.S., Ryan S.J. Ultrastructure of traction retinal detachment in rhesus monkey eyes after a posterior penetrating ocular injury. Am. J. Ophthalmol. 1980, 90:829-845.
    • (1980) Am. J. Ophthalmol. , vol.90 , pp. 829-845
    • Cleary, P.E.1    Minckler, D.S.2    Ryan, S.J.3
  • 62
    • 0019345845 scopus 로고
    • Mechanisms in traction retinal detachment
    • Cleary P.E., Ryan S.J. Mechanisms in traction retinal detachment. Dev. Ophthalmol. 1981, 2:328-333.
    • (1981) Dev. Ophthalmol. , vol.2 , pp. 328-333
    • Cleary, P.E.1    Ryan, S.J.2
  • 63
    • 17844378742 scopus 로고    scopus 로고
    • The N-terminal Ac-EEED sequence plays a role in α-smooth-muscle actin incorporation into stress fibers
    • Clement S., Hinz B., Dugina V., Gabbiani G., Chaponnier C. The N-terminal Ac-EEED sequence plays a role in α-smooth-muscle actin incorporation into stress fibers. J. Cell Sci. 2005, 118:1395-1404.
    • (2005) J. Cell Sci. , vol.118 , pp. 1395-1404
    • Clement, S.1    Hinz, B.2    Dugina, V.3    Gabbiani, G.4    Chaponnier, C.5
  • 65
    • 0032821129 scopus 로고    scopus 로고
    • Human anti-transforming growth factor-beta2 antibody: a new glaucoma anti-scarring agent
    • Cordeiro M.F., Gay J.A., Khaw P.T. Human anti-transforming growth factor-beta2 antibody: a new glaucoma anti-scarring agent. Investig. Ophthalmol. Vis. Sci. 1999, 40:2225-2234.
    • (1999) Investig. Ophthalmol. Vis. Sci. , vol.40 , pp. 2225-2234
    • Cordeiro, M.F.1    Gay, J.A.2    Khaw, P.T.3
  • 66
    • 0032820482 scopus 로고    scopus 로고
    • Transforming growth factor-beta1, -beta2, and -beta3 in vivo: effects on normal and mitomycin C-modulated conjunctival scarring
    • Cordeiro M.F., Reichel M.B., Gay J.A., D'Esposita F., Alexander R.A., Khaw P.T. Transforming growth factor-beta1, -beta2, and -beta3 in vivo: effects on normal and mitomycin C-modulated conjunctival scarring. Investig. Ophthalmol. Vis. Sci. 1999, 40:1975-1982.
    • (1999) Investig. Ophthalmol. Vis. Sci. , vol.40 , pp. 1975-1982
    • Cordeiro, M.F.1    Reichel, M.B.2    Gay, J.A.3    D'Esposita, F.4    Alexander, R.A.5    Khaw, P.T.6
  • 68
    • 79952340427 scopus 로고    scopus 로고
    • Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
    • Cox T.R., Erler J.T. Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer. Dis. Model Mech. 2011, 4:165-178.
    • (2011) Dis. Model Mech. , vol.4 , pp. 165-178
    • Cox, T.R.1    Erler, J.T.2
  • 69
    • 80855143589 scopus 로고    scopus 로고
    • Myocardin-related transcription factors A and B are key regulators of TGF-beta1-induced fibroblast to myofibroblast differentiation
    • Crider B.J., Risinger G.M., Haaksma C.J., Howard E.W., Tomasek J.J. Myocardin-related transcription factors A and B are key regulators of TGF-beta1-induced fibroblast to myofibroblast differentiation. J. Investig. Dermatol. 2011, 131:2378-2385.
    • (2011) J. Investig. Dermatol. , vol.131 , pp. 2378-2385
    • Crider, B.J.1    Risinger, G.M.2    Haaksma, C.J.3    Howard, E.W.4    Tomasek, J.J.5
  • 70
    • 44949107350 scopus 로고    scopus 로고
    • Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells
    • Cushing M.C., Mariner P.D., Liao J.T., Sims E.A., Anseth K.S. Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells. Faseb J. 2008, 22:1769-1777.
    • (2008) Faseb J. , vol.22 , pp. 1769-1777
    • Cushing, M.C.1    Mariner, P.D.2    Liao, J.T.3    Sims, E.A.4    Anseth, K.S.5
  • 71
    • 0002898142 scopus 로고    scopus 로고
    • Reversal of the wound healing deficit in diabetic rats by combined basic fibroblast growth factor and transforming growth factor-beta1 therapy
    • Davidson J.M., Broadley K.N., Quaglino D. Reversal of the wound healing deficit in diabetic rats by combined basic fibroblast growth factor and transforming growth factor-beta1 therapy. Wound Repair Regen. 1997, 5:77-88.
    • (1997) Wound Repair Regen. , vol.5 , pp. 77-88
    • Davidson, J.M.1    Broadley, K.N.2    Quaglino, D.3
  • 73
    • 84898833444 scopus 로고    scopus 로고
    • Myofibroblasts: trust your heart and let fate decide
    • Davis J., Molkentin J.D. Myofibroblasts: trust your heart and let fate decide. J. Mol. Cell Cardiol. 2014, 70:9-18.
    • (2014) J. Mol. Cell Cardiol. , vol.70 , pp. 9-18
    • Davis, J.1    Molkentin, J.D.2
  • 75
    • 84886769903 scopus 로고    scopus 로고
    • Canonical Wnt signalling as a key regulator of fibrogenesis - implications for targeted therapies?
    • Dees C., Distler J.H. Canonical Wnt signalling as a key regulator of fibrogenesis - implications for targeted therapies?. Exp. Dermatol. 2013, 22:710-713.
    • (2013) Exp. Dermatol. , vol.22 , pp. 710-713
    • Dees, C.1    Distler, J.H.2
  • 76
    • 79957471970 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF/CCN2) ELISA: a novel tool for monitoring fibrosis
    • Dendooven A., Gerritsen K.G., Nguyen T.Q., Kok R.J., Goldschmeding R. Connective tissue growth factor (CTGF/CCN2) ELISA: a novel tool for monitoring fibrosis. Biomarkers 2011, 16:289-301.
    • (2011) Biomarkers , vol.16 , pp. 289-301
    • Dendooven, A.1    Gerritsen, K.G.2    Nguyen, T.Q.3    Kok, R.J.4    Goldschmeding, R.5
  • 77
    • 0027212686 scopus 로고
    • Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
    • Desmoulière A., Geinoz A., Gabbiani F., Gabbiani G. Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J. Cell Biol. 1993, 122:103-111.
    • (1993) J. Cell Biol. , vol.122 , pp. 103-111
    • Desmoulière, A.1    Geinoz, A.2    Gabbiani, F.3    Gabbiani, G.4
  • 78
    • 0028851160 scopus 로고
    • Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar
    • Desmoulière A., Redard M., Darby I., Gabbiani G. Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am. J. Pathol. 1995, 146:56-66.
    • (1995) Am. J. Pathol. , vol.146 , pp. 56-66
    • Desmoulière, A.1    Redard, M.2    Darby, I.3    Gabbiani, G.4
  • 80
  • 81
    • 84862763855 scopus 로고    scopus 로고
    • Matrix-dependent perturbation of TGFbeta signaling and disease
    • Doyle J.J., Gerber E.E., Dietz H.C. Matrix-dependent perturbation of TGFbeta signaling and disease. FEBS Lett. 2012, 586:2003-2015.
    • (2012) FEBS Lett. , vol.586 , pp. 2003-2015
    • Doyle, J.J.1    Gerber, E.E.2    Dietz, H.C.3
  • 84
    • 84902179695 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms in kidney fibrosis
    • Duffield J.S. Cellular and molecular mechanisms in kidney fibrosis. J. Clin. Investig. 2014, 124:2299-2306.
    • (2014) J. Clin. Investig. , vol.124 , pp. 2299-2306
    • Duffield, J.S.1
  • 87
    • 0034778401 scopus 로고    scopus 로고
    • Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors
    • Dugina V., Fontao L., Chaponnier C., Vasiliev J., Gabbiani G. Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors. J. Cell Sci. 2001, 114:3285-3296.
    • (2001) J. Cell Sci. , vol.114 , pp. 3285-3296
    • Dugina, V.1    Fontao, L.2    Chaponnier, C.3    Vasiliev, J.4    Gabbiani, G.5
  • 88
    • 84864722077 scopus 로고    scopus 로고
    • Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury
    • Dulauroy S., Di Carlo S.E., Langa F., Eberl G., Peduto L. Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury. Nat. Med. 2012, 18:1262-1270.
    • (2012) Nat. Med. , vol.18 , pp. 1262-1270
    • Dulauroy, S.1    Di Carlo, S.E.2    Langa, F.3    Eberl, G.4    Peduto, L.5
  • 89
    • 33747884984 scopus 로고    scopus 로고
    • Biomechanics and wound healing in the cornea
    • Dupps W.J., Wilson S.E. Biomechanics and wound healing in the cornea. Exp. Eye Res. 2006, 83:709-720.
    • (2006) Exp. Eye Res. , vol.83 , pp. 709-720
    • Dupps, W.J.1    Wilson, S.E.2
  • 91
    • 77955107756 scopus 로고    scopus 로고
    • Age-dependent regional mechanical properties of the rat hippocampus and cortex
    • Elkin B.S., Ilankovan A., Morrison B. Age-dependent regional mechanical properties of the rat hippocampus and cortex. J. Biomech. Eng. 2010, 132:011010.
    • (2010) J. Biomech. Eng. , vol.132 , pp. 011010
    • Elkin, B.S.1    Ilankovan, A.2    Morrison, B.3
  • 92
    • 33847020833 scopus 로고    scopus 로고
    • Inflammation in wound repair: molecular and cellular mechanisms
    • Eming S.A., Krieg T., Davidson J.M. Inflammation in wound repair: molecular and cellular mechanisms. J. Investig. Dermatol. 2007, 127:514-525.
    • (2007) J. Investig. Dermatol. , vol.127 , pp. 514-525
    • Eming, S.A.1    Krieg, T.2    Davidson, J.M.3
  • 93
    • 4544264684 scopus 로고    scopus 로고
    • Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments
    • Engler A.J., Griffin M.A., Sen S., Bonnemann C.G., Sweeney H.L., Discher D.E. Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments. J. Cell Biol. 2004, 166:877-887.
    • (2004) J. Cell Biol. , vol.166 , pp. 877-887
    • Engler, A.J.1    Griffin, M.A.2    Sen, S.3    Bonnemann, C.G.4    Sweeney, H.L.5    Discher, D.E.6
  • 94
    • 77956491603 scopus 로고    scopus 로고
    • Enhanced cell accumulation and collagen processing by keratocytes cultured under agarose and in media containing IGF-I, TGF-beta or PDGF
    • Etheredge L., Kane B.P., Valkov N., Adams S., Birk D.E., Hassell J.R. Enhanced cell accumulation and collagen processing by keratocytes cultured under agarose and in media containing IGF-I, TGF-beta or PDGF. Matrix Biol. 2010, 29:519-524.
    • (2010) Matrix Biol. , vol.29 , pp. 519-524
    • Etheredge, L.1    Kane, B.P.2    Valkov, N.3    Adams, S.4    Birk, D.E.5    Hassell, J.R.6
  • 97
    • 0034796416 scopus 로고    scopus 로고
    • Transforming growth factor-beta-stimulated connective tissue growth factor expression during corneal myofibroblast differentiation
    • Folger P.A., Zekaria D., Grotendorst G., Masur S.K. Transforming growth factor-beta-stimulated connective tissue growth factor expression during corneal myofibroblast differentiation. Investig. Ophthalmol. Vis. Sci. 2001, 42:2534-2541.
    • (2001) Investig. Ophthalmol. Vis. Sci. , vol.42 , pp. 2534-2541
    • Folger, P.A.1    Zekaria, D.2    Grotendorst, G.3    Masur, S.K.4
  • 98
    • 77952335298 scopus 로고    scopus 로고
    • A new lock-step mechanism of matrix remodelling based on subcellular contractile events
    • Follonier Castella L., Buscemi L., Godbout C., Meister J.J., Hinz B. A new lock-step mechanism of matrix remodelling based on subcellular contractile events. J. Cell Sci. 2010, 123:1751-1760.
    • (2010) J. Cell Sci. , vol.123 , pp. 1751-1760
    • Follonier Castella, L.1    Buscemi, L.2    Godbout, C.3    Meister, J.J.4    Hinz, B.5
  • 99
    • 84905732910 scopus 로고    scopus 로고
    • Preparing the ground for tissue regeneration: from mechanism to therapy
    • Forbes S.J., Rosenthal N. Preparing the ground for tissue regeneration: from mechanism to therapy. Nat. Med. 2014, 20:857-869.
    • (2014) Nat. Med. , vol.20 , pp. 857-869
    • Forbes, S.J.1    Rosenthal, N.2
  • 101
    • 0015225464 scopus 로고
    • Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
    • Gabbiani G., Ryan G.B., Majno G. Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experientia 1971, 27:549-550.
    • (1971) Experientia , vol.27 , pp. 549-550
    • Gabbiani, G.1    Ryan, G.B.2    Majno, G.3
  • 102
    • 33646889540 scopus 로고    scopus 로고
    • Transforming growth factor beta2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: regulation by extracellular matrix proteins and hepatocyte growth factor
    • Gamulescu M.A., Chen Y., He S., Spee C., Jin M., Ryan S.J., Hinton D.R. Transforming growth factor beta2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: regulation by extracellular matrix proteins and hepatocyte growth factor. Exp. Eye Res. 2006, 83:212-222.
    • (2006) Exp. Eye Res. , vol.83 , pp. 212-222
    • Gamulescu, M.A.1    Chen, Y.2    He, S.3    Spee, C.4    Jin, M.5    Ryan, S.J.6    Hinton, D.R.7
  • 104
    • 2142716774 scopus 로고    scopus 로고
    • Involvement of CTGF in TGF-beta1-stimulation of myofibroblast differentiation and collagen matrix contraction in the presence of mechanical stress
    • Garrett Q., Khaw P.T., Blalock T.D., Schultz G.S., Grotendorst G.R., Daniels J.T. Involvement of CTGF in TGF-beta1-stimulation of myofibroblast differentiation and collagen matrix contraction in the presence of mechanical stress. Investig. Ophthalmol. Vis. Sci. 2004, 45:1109-1116.
    • (2004) Investig. Ophthalmol. Vis. Sci. , vol.45 , pp. 1109-1116
    • Garrett, Q.1    Khaw, P.T.2    Blalock, T.D.3    Schultz, G.S.4    Grotendorst, G.R.5    Daniels, J.T.6
  • 105
    • 78651471059 scopus 로고    scopus 로고
    • Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies
    • Gauglitz G.G., Korting H.C., Pavicic T., Ruzicka T., Jeschke M.G. Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies. Mol. Med. 2011, 17:113-125.
    • (2011) Mol. Med. , vol.17 , pp. 113-125
    • Gauglitz, G.G.1    Korting, H.C.2    Pavicic, T.3    Ruzicka, T.4    Jeschke, M.G.5
  • 107
    • 84857651851 scopus 로고    scopus 로고
    • Epithelial cells utilize cortical actin/myosin to activate latent TGF-beta through integrin alpha(v)beta(6)-dependent physical force
    • Giacomini M.M., Travis M.A., Kudo M., Sheppard D. Epithelial cells utilize cortical actin/myosin to activate latent TGF-beta through integrin alpha(v)beta(6)-dependent physical force. Exp. Cell Res. 2012, 318:716-722.
    • (2012) Exp. Cell Res. , vol.318 , pp. 716-722
    • Giacomini, M.M.1    Travis, M.A.2    Kudo, M.3    Sheppard, D.4
  • 109
    • 30944452186 scopus 로고    scopus 로고
    • Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers
    • Goffin J.M., Pittet P., Csucs G., Lussi J.W., Meister J.J., Hinz B. Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers. J. Cell Biol. 2006, 172:259-268.
    • (2006) J. Cell Biol. , vol.172 , pp. 259-268
    • Goffin, J.M.1    Pittet, P.2    Csucs, G.3    Lussi, J.W.4    Meister, J.J.5    Hinz, B.6
  • 111
    • 67649922571 scopus 로고    scopus 로고
    • A transgenic mouse model of inducible macrophage depletion: effects of diphtheria toxin-driven lysozyme M-specific cell lineage ablation on wound inflammatory, angiogenic, and contractive processes
    • Goren I., Allmann N., Yogev N., Schurmann C., Linke A., Holdener M., Waisman A., Pfeilschifter J., Frank S. A transgenic mouse model of inducible macrophage depletion: effects of diphtheria toxin-driven lysozyme M-specific cell lineage ablation on wound inflammatory, angiogenic, and contractive processes. Am. J. Pathol. 2009, 175:132-147.
    • (2009) Am. J. Pathol. , vol.175 , pp. 132-147
    • Goren, I.1    Allmann, N.2    Yogev, N.3    Schurmann, C.4    Linke, A.5    Holdener, M.6    Waisman, A.7    Pfeilschifter, J.8    Frank, S.9
  • 112
    • 81855199496 scopus 로고    scopus 로고
    • Interstitial guidance of cancer invasion
    • Gritsenko P.G., Ilina O., Friedl P. Interstitial guidance of cancer invasion. J. Pathol. 2012, 226:185-199.
    • (2012) J. Pathol. , vol.226 , pp. 185-199
    • Gritsenko, P.G.1    Ilina, O.2    Friedl, P.3
  • 113
    • 34748861947 scopus 로고    scopus 로고
    • A phase III study of subconjunctival human anti-transforming growth factor beta(2) monoclonal antibody (CAT-152) to prevent scarring after first-time trabeculectomy
    • Group C.A.T.T.S., Khaw P., Grehn F., Hollo G., Overton B., Wilson R., Vogel R., Smith Z. A phase III study of subconjunctival human anti-transforming growth factor beta(2) monoclonal antibody (CAT-152) to prevent scarring after first-time trabeculectomy. Ophthalmology 2007, 114:1822-1830.
    • (2007) Ophthalmology , vol.114 , pp. 1822-1830
    • Group, C.A.T.T.S.1    Khaw, P.2    Grehn, F.3    Hollo, G.4    Overton, B.5    Wilson, R.6    Vogel, R.7    Smith, Z.8
  • 114
    • 64049099101 scopus 로고    scopus 로고
    • Fibrocontractive Muller cell phenotypes in proliferative diabetic retinopathy
    • Guidry C., King J.L., Mason J.O. Fibrocontractive Muller cell phenotypes in proliferative diabetic retinopathy. Investig. Ophthalmol. Vis. Sci. 2009, 50:1929-1939.
    • (2009) Investig. Ophthalmol. Vis. Sci. , vol.50 , pp. 1929-1939
    • Guidry, C.1    King, J.L.2    Mason, J.O.3
  • 115
    • 77957787923 scopus 로고    scopus 로고
    • Hyaluronan synthesis mediates the fibrotic response of keratocytes to transforming growth factor beta
    • Guo N., Li X., Mann M.M., Funderburgh M.L., Du Y., Funderburgh J.L. Hyaluronan synthesis mediates the fibrotic response of keratocytes to transforming growth factor beta. J. Biol. Chem. 2010, 285:32012-32019.
    • (2010) J. Biol. Chem. , vol.285 , pp. 32012-32019
    • Guo, N.1    Li, X.2    Mann, M.M.3    Funderburgh, M.L.4    Du, Y.5    Funderburgh, J.L.6
  • 116
    • 84883143537 scopus 로고    scopus 로고
    • Nuclear translocation of myocardin-related transcription factor-A during transforming growth factor beta-induced epithelial to mesenchymal transition of lens epithelial cells
    • Gupta M., Korol A., West-Mays J.A. Nuclear translocation of myocardin-related transcription factor-A during transforming growth factor beta-induced epithelial to mesenchymal transition of lens epithelial cells. Mol. Vis. 2013, 19:1017-1028.
    • (2013) Mol. Vis. , vol.19 , pp. 1017-1028
    • Gupta, M.1    Korol, A.2    West-Mays, J.A.3
  • 117
    • 84865411430 scopus 로고    scopus 로고
    • Transduction of mechanical and cytoskeletal cues by YAP and TAZ
    • Halder G., Dupont S., Piccolo S. Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat. Rev. Mol. Cell Biol. 2012, 13:591-600.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 591-600
    • Halder, G.1    Dupont, S.2    Piccolo, S.3
  • 118
    • 0028567054 scopus 로고
    • TGF-beta 1 induces lens cells to accumulate alpha-smooth muscle actin, a marker for subcapsular cataracts
    • Hales A.M., Schulz M.W., Chamberlain C.G., McAvoy J.W. TGF-beta 1 induces lens cells to accumulate alpha-smooth muscle actin, a marker for subcapsular cataracts. Curr. Eye Res. 1994, 13:885-890.
    • (1994) Curr. Eye Res. , vol.13 , pp. 885-890
    • Hales, A.M.1    Schulz, M.W.2    Chamberlain, C.G.3    McAvoy, J.W.4
  • 119
    • 84924623581 scopus 로고    scopus 로고
    • Sustained beta-catenin activity in dermal fibroblasts promotes fibrosis by up-regulating expression of extracellular matrix protein-coding genes
    • Hamburg-Schields E., DiNuoscio G.J., Mullin N.K., Lafayatis R., Atit R.P. Sustained beta-catenin activity in dermal fibroblasts promotes fibrosis by up-regulating expression of extracellular matrix protein-coding genes. J. Pathol. 2014, 235:686-697.
    • (2014) J. Pathol. , vol.235 , pp. 686-697
    • Hamburg-Schields, E.1    DiNuoscio, G.J.2    Mullin, N.K.3    Lafayatis, R.4    Atit, R.P.5
  • 120
    • 79955955725 scopus 로고    scopus 로고
    • Elasticity-dependent modulation of TGF-beta responses in human trabecular meshwork cells
    • Han H., Wecker T., Grehn F., Schlunck G. Elasticity-dependent modulation of TGF-beta responses in human trabecular meshwork cells. Investig. Ophthalmol. Vis. Sci. 2011, 52:2889-2896.
    • (2011) Investig. Ophthalmol. Vis. Sci. , vol.52 , pp. 2889-2896
    • Han, H.1    Wecker, T.2    Grehn, F.3    Schlunck, G.4
  • 121
    • 77955842202 scopus 로고    scopus 로고
    • The molecular basis of corneal transparency
    • Hassell J.R., Birk D.E. The molecular basis of corneal transparency. Exp. Eye Res. 2010, 91:326-335.
    • (2010) Exp. Eye Res. , vol.91 , pp. 326-335
    • Hassell, J.R.1    Birk, D.E.2
  • 122
    • 33645384039 scopus 로고    scopus 로고
    • Synergistic effect of platelet-activating factor and tumor necrosis factor-alpha on corneal myofibroblast apoptosis
    • He J., Bazan H.E. Synergistic effect of platelet-activating factor and tumor necrosis factor-alpha on corneal myofibroblast apoptosis. Investig. Ophthalmol. Vis. Sci. 2006, 47:883-891.
    • (2006) Investig. Ophthalmol. Vis. Sci. , vol.47 , pp. 883-891
    • He, J.1    Bazan, H.E.2
  • 123
    • 84878224757 scopus 로고    scopus 로고
    • Macrophages are essential for the early wound healing response and the formation of a fibrovascular scar
    • He L., Marneros A.G. Macrophages are essential for the early wound healing response and the formation of a fibrovascular scar. Am. J. Pathol. 2013, 182:2407-2417.
    • (2013) Am. J. Pathol. , vol.182 , pp. 2407-2417
    • He, L.1    Marneros, A.G.2
  • 124
    • 79959348136 scopus 로고    scopus 로고
    • Reversible differentiation of myofibroblasts by MyoD
    • Hecker L., Jagirdar R., Jin T., Thannickal V.J. Reversible differentiation of myofibroblasts by MyoD. Exp. Cell Res. 2011, 317:1914-1921.
    • (2011) Exp. Cell Res. , vol.317 , pp. 1914-1921
    • Hecker, L.1    Jagirdar, R.2    Jin, T.3    Thannickal, V.J.4
  • 125
    • 84890467312 scopus 로고    scopus 로고
    • Targeting the PDGF signaling pathway in tumor treatment
    • Heldin C.H. Targeting the PDGF signaling pathway in tumor treatment. Cell Commun. Signal 2013, 11:97.
    • (2013) Cell Commun. Signal , vol.11 , pp. 97
    • Heldin, C.H.1
  • 127
    • 84877025203 scopus 로고    scopus 로고
    • Integrin-mediated regulation of TGF beta in fibrosis
    • Henderson N.C., Sheppard D. Integrin-mediated regulation of TGF beta in fibrosis. Biochim. Biophys. Acta 2013, 1832:891-896.
    • (2013) Biochim. Biophys. Acta , vol.1832 , pp. 891-896
    • Henderson, N.C.1    Sheppard, D.2
  • 128
    • 0242384852 scopus 로고    scopus 로고
    • Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3
    • Higashi K., Inagaki Y., Fujimori K., Nakao A., Kaneko H., Nakatsuka I. Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3. J. Biol. Chem. 2003, 278:43470-43479.
    • (2003) J. Biol. Chem. , vol.278 , pp. 43470-43479
    • Higashi, K.1    Inagaki, Y.2    Fujimori, K.3    Nakao, A.4    Kaneko, H.5    Nakatsuka, I.6
  • 129
    • 33644948094 scopus 로고    scopus 로고
    • Masters and servants of the force: the role of matrix adhesions in myofibroblast force perception and transmission
    • Hinz B. Masters and servants of the force: the role of matrix adhesions in myofibroblast force perception and transmission. Eur. J. Cell Biol. 2006, 85:175-181.
    • (2006) Eur. J. Cell Biol. , vol.85 , pp. 175-181
    • Hinz, B.1
  • 130
    • 33847084614 scopus 로고    scopus 로고
    • Formation and function of the myofibroblast during tissue repair
    • Hinz B. Formation and function of the myofibroblast during tissue repair. J. Investig. Dermatol. 2007, 127:526-537.
    • (2007) J. Investig. Dermatol. , vol.127 , pp. 526-537
    • Hinz, B.1
  • 131
    • 65549160523 scopus 로고    scopus 로고
    • Tissue stiffness, latent TGF-beta1 activation, and mechanical signal transduction: implications for the pathogenesis and treatment of fibrosis
    • Hinz B. Tissue stiffness, latent TGF-beta1 activation, and mechanical signal transduction: implications for the pathogenesis and treatment of fibrosis. Curr. Rheumatol. Rep. 2009, 11:120-126.
    • (2009) Curr. Rheumatol. Rep. , vol.11 , pp. 120-126
    • Hinz, B.1
  • 132
    • 77955051583 scopus 로고    scopus 로고
    • The myofibroblast in connective tissue repair and regeneration
    • Woodhead Publishing Ltd., Cambridge, UK, C.A.J. Ralphs (Ed.)
    • Hinz B. The myofibroblast in connective tissue repair and regeneration. Regenerative Medicine and Biomaterials for the Repair of Connective Tissues 2010, 39-82. Woodhead Publishing Ltd., Cambridge, UK. C.A.J. Ralphs (Ed.).
    • (2010) Regenerative Medicine and Biomaterials for the Repair of Connective Tissues , pp. 39-82
    • Hinz, B.1
  • 133
    • 72149111953 scopus 로고    scopus 로고
    • The myofibroblast: paradigm for a mechanically active cell
    • Hinz B. The myofibroblast: paradigm for a mechanically active cell. J. Biomech. 2010, 43:146-155.
    • (2010) J. Biomech. , vol.43 , pp. 146-155
    • Hinz, B.1
  • 134
    • 84894635703 scopus 로고    scopus 로고
    • It has to be the alpha: myofibroblast integrins activate latent TGF-beta1
    • Hinz B. It has to be the alpha: myofibroblast integrins activate latent TGF-beta1. Nat. Med. 2013, 19:1567-1568.
    • (2013) Nat. Med. , vol.19 , pp. 1567-1568
    • Hinz, B.1
  • 135
    • 84881486467 scopus 로고    scopus 로고
    • Matrix mechanics and regulation of the fibroblast phenotype
    • Hinz B. Matrix mechanics and regulation of the fibroblast phenotype. Periodontol 2013, 2000(63):14-28.
    • (2013) Periodontol , vol.2000 , Issue.63 , pp. 14-28
    • Hinz, B.1
  • 136
    • 84961674191 scopus 로고    scopus 로고
    • The matrix and the transforming growth factor: tale of a strained relationship
    • [e-pub ahead of print]
    • Hinz B. The matrix and the transforming growth factor: tale of a strained relationship. Matrix Biol. 2015, [e-pub ahead of print].
    • (2015) Matrix Biol.
    • Hinz, B.1
  • 137
    • 0035159094 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin expression upregulates fibroblast contractile activity
    • Hinz B., Celetta G., Tomasek J.J., Gabbiani G., Chaponnier C. Alpha-smooth muscle actin expression upregulates fibroblast contractile activity. Mol. Biol. Cell 2001, 12:2730-2741.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 2730-2741
    • Hinz, B.1    Celetta, G.2    Tomasek, J.J.3    Gabbiani, G.4    Chaponnier, C.5
  • 138
    • 0037632844 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts
    • Hinz B., Dugina V., Ballestrem C., Wehrle-Haller B., Chaponnier C. Alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts. Mol. Biol. Cell 2003, 14:2508-2519.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 2508-2519
    • Hinz, B.1    Dugina, V.2    Ballestrem, C.3    Wehrle-Haller, B.4    Chaponnier, C.5
  • 139
    • 0142089586 scopus 로고    scopus 로고
    • Cell-matrix and cell-cell contacts of myofibroblasts: role in connective tissue remodeling
    • Hinz B., Gabbiani G. Cell-matrix and cell-cell contacts of myofibroblasts: role in connective tissue remodeling. Thromb. Haemost. 2003, 90:993-1002.
    • (2003) Thromb. Haemost. , vol.90 , pp. 993-1002
    • Hinz, B.1    Gabbiani, G.2
  • 141
    • 0037070964 scopus 로고    scopus 로고
    • The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo
    • Hinz B., Gabbiani G., Chaponnier C. The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo. J. Cell Biol. 2002, 157:657-663.
    • (2002) J. Cell Biol. , vol.157 , pp. 657-663
    • Hinz, B.1    Gabbiani, G.2    Chaponnier, C.3
  • 142
    • 84961632167 scopus 로고    scopus 로고
    • Myofibroblast
    • Lippincott-Williams & Wilkins Pub., Philadelphia, U.S.A, S.E. Mills (Ed.)
    • Hinz B., Gabbiani G., Seemayer T.A., Schürch W. Myofibroblast. Histology for Pathologists 2012, 131-177. Lippincott-Williams & Wilkins Pub., Philadelphia, U.S.A. fouth ed. S.E. Mills (Ed.).
    • (2012) Histology for Pathologists , pp. 131-177
    • Hinz, B.1    Gabbiani, G.2    Seemayer, T.A.3    Schürch, W.4
  • 143
    • 84957861616 scopus 로고    scopus 로고
    • Integrin function in heart fibrosis: mechanical strain, TGF-β1 activation and collagen glycation
    • DeGruyter, Berlin, Germany, N. Karamanos (Ed.)
    • Hinz B., McCulloch C.M. Integrin function in heart fibrosis: mechanical strain, TGF-β1 activation and collagen glycation. Extracellular Matrix: Pathobiology and Signalling 2012, 407-431. DeGruyter, Berlin, Germany. N. Karamanos (Ed.).
    • (2012) Extracellular Matrix: Pathobiology and Signalling , pp. 407-431
    • Hinz, B.1    McCulloch, C.M.2
  • 146
    • 34948830974 scopus 로고    scopus 로고
    • The tooth attachment mechanism defined by structure, chemical composition and mechanical properties of collagen fibers in the periodontium
    • Ho S.P., Marshall S.J., Ryder M.I., Marshall G.W. The tooth attachment mechanism defined by structure, chemical composition and mechanical properties of collagen fibers in the periodontium. Biomaterials 2007, 28:5238-5245.
    • (2007) Biomaterials , vol.28 , pp. 5238-5245
    • Ho, S.P.1    Marshall, S.J.2    Ryder, M.I.3    Marshall, G.W.4
  • 147
    • 0025113421 scopus 로고
    • Bilateral keloid-like myofibroblastic proliferations of the cornea in children
    • Holbach L.M., Font R.L., Shivitz I.A., Jones D.B. Bilateral keloid-like myofibroblastic proliferations of the cornea in children. Ophthalmology 1990, 97:1188-1193.
    • (1990) Ophthalmology , vol.97 , pp. 1188-1193
    • Holbach, L.M.1    Font, R.L.2    Shivitz, I.A.3    Jones, D.B.4
  • 151
    • 84908320955 scopus 로고    scopus 로고
    • Biological activity differences between TGF-beta1 and TGF-beta3 correlate with differences in the rigidity and arrangement of their component monomers
    • Huang T., Schor S.L., Hinck A.P. Biological activity differences between TGF-beta1 and TGF-beta3 correlate with differences in the rigidity and arrangement of their component monomers. Biochemistry 2014, 53:5737-5749.
    • (2014) Biochemistry , vol.53 , pp. 5737-5749
    • Huang, T.1    Schor, S.L.2    Hinck, A.P.3
  • 152
    • 81255157548 scopus 로고    scopus 로고
    • Relaxin regulates myofibroblast contractility and protects against lung fibrosis
    • Huang X., Gai Y., Yang N., Lu B., Samuel C.S., Thannickal V.J., Zhou Y. Relaxin regulates myofibroblast contractility and protects against lung fibrosis. Am. J. Pathol. 2011, 179:2751-2765.
    • (2011) Am. J. Pathol. , vol.179 , pp. 2751-2765
    • Huang, X.1    Gai, Y.2    Yang, N.3    Lu, B.4    Samuel, C.S.5    Thannickal, V.J.6    Zhou, Y.7
  • 153
    • 73349109824 scopus 로고    scopus 로고
    • Temporal and spatial distribution of TGF-beta isoforms and signaling intermediates in corneal regenerative wound repair
    • Huh M.I., Chang Y., Jung J.C. Temporal and spatial distribution of TGF-beta isoforms and signaling intermediates in corneal regenerative wound repair. Histol. Histopathol. 2009, 24:1405-1416.
    • (2009) Histol. Histopathol. , vol.24 , pp. 1405-1416
    • Huh, M.I.1    Chang, Y.2    Jung, J.C.3
  • 155
    • 84884792732 scopus 로고    scopus 로고
    • Coronary adventitial cells are linked to perivascular cardiac fibrosis via TGFbeta1 signaling in the mdx mouse model of Duchenne muscular dystrophy
    • Ieronimakis N., Hays A.L., Janebodin K., Mahoney W.M., Duffield J.S., Majesky M.W., Reyes M. Coronary adventitial cells are linked to perivascular cardiac fibrosis via TGFbeta1 signaling in the mdx mouse model of Duchenne muscular dystrophy. J. Mol. Cell Cardiol. 2013, 63:122-134.
    • (2013) J. Mol. Cell Cardiol. , vol.63 , pp. 122-134
    • Ieronimakis, N.1    Hays, A.L.2    Janebodin, K.3    Mahoney, W.M.4    Duffield, J.S.5    Majesky, M.W.6    Reyes, M.7
  • 157
    • 2442636666 scopus 로고    scopus 로고
    • Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells
    • Ito T., Williams J.D., Fraser D., Phillips A.O. Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells. Am. J. Pathol. 2004, 164:1979-1988.
    • (2004) Am. J. Pathol. , vol.164 , pp. 1979-1988
    • Ito, T.1    Williams, J.D.2    Fraser, D.3    Phillips, A.O.4
  • 158
    • 84872014405 scopus 로고    scopus 로고
    • Involvement of PDGF in fibrosis and scleroderma: recent insights from animal models and potential therapeutic opportunities
    • Iwayama T., Olson L.E. Involvement of PDGF in fibrosis and scleroderma: recent insights from animal models and potential therapeutic opportunities. Curr. Rheumatol. Rep. 2013, 15:304.
    • (2013) Curr. Rheumatol. Rep. , vol.15 , pp. 304
    • Iwayama, T.1    Olson, L.E.2
  • 159
    • 33644872861 scopus 로고    scopus 로고
    • Involvement of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in corneal fibroblasts during corneal wound healing
    • Izumi K., Kurosaka D., Iwata T., Oguchi Y., Tanaka Y., Mashima Y., Tsubota K. Involvement of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in corneal fibroblasts during corneal wound healing. Investig. Ophthalmol. Vis. Sci. 2006, 47:591-598.
    • (2006) Investig. Ophthalmol. Vis. Sci. , vol.47 , pp. 591-598
    • Izumi, K.1    Kurosaka, D.2    Iwata, T.3    Oguchi, Y.4    Tanaka, Y.5    Mashima, Y.6    Tsubota, K.7
  • 161
    • 43049146157 scopus 로고    scopus 로고
    • The role of proteases in transforming growth factor-beta activation
    • Jenkins G. The role of proteases in transforming growth factor-beta activation. Int. J. Biochem. Cell Biol. 2008, 40:1068-1078.
    • (2008) Int. J. Biochem. Cell Biol. , vol.40 , pp. 1068-1078
    • Jenkins, G.1
  • 163
    • 0029743832 scopus 로고    scopus 로고
    • Induction of alpha-smooth muscle actin expression and myofibroblast transformation in cultured corneal keratocytes
    • Jester J.V., Barry-Lane P.A., Cavanagh H.D., Petroll W.M. Induction of alpha-smooth muscle actin expression and myofibroblast transformation in cultured corneal keratocytes. Cornea 1996, 15:505-516.
    • (1996) Cornea , vol.15 , pp. 505-516
    • Jester, J.V.1    Barry-Lane, P.A.2    Cavanagh, H.D.3    Petroll, W.M.4
  • 164
    • 84858951956 scopus 로고    scopus 로고
    • Myofibroblast differentiation modulates keratocyte crystallin protein expression, concentration, and cellular light scattering
    • Jester J.V., Brown D., Pappa A., Vasiliou V. Myofibroblast differentiation modulates keratocyte crystallin protein expression, concentration, and cellular light scattering. Investig. Ophthalmol. Vis. Sci. 2012, 53:770-778.
    • (2012) Investig. Ophthalmol. Vis. Sci. , vol.53 , pp. 770-778
    • Jester, J.V.1    Brown, D.2    Pappa, A.3    Vasiliou, V.4
  • 165
    • 0036882153 scopus 로고    scopus 로고
    • TGFbeta induced myofibroblast differentiation of rabbit keratocytes requires synergistic TGFbeta, PDGF and integrin signaling
    • Jester J.V., Huang J., Petroll W.M., Cavanagh H.D. TGFbeta induced myofibroblast differentiation of rabbit keratocytes requires synergistic TGFbeta, PDGF and integrin signaling. Exp. Eye Res. 2002, 75:645-657.
    • (2002) Exp. Eye Res. , vol.75 , pp. 645-657
    • Jester, J.V.1    Huang, J.2    Petroll, W.M.3    Cavanagh, H.D.4
  • 166
    • 0033064004 scopus 로고    scopus 로고
    • Corneal stromal wound healing in refractive surgery: the role of myofibroblasts
    • Jester J.V., Petroll W.M., Cavanagh H.D. Corneal stromal wound healing in refractive surgery: the role of myofibroblasts. Prog. Retin Eye Res. 1999, 18:311-356.
    • (1999) Prog. Retin Eye Res. , vol.18 , pp. 311-356
    • Jester, J.V.1    Petroll, W.M.2    Cavanagh, H.D.3
  • 167
    • 84893643399 scopus 로고    scopus 로고
    • Novel Rho/MRTF/SRF inhibitors block matrix-stiffness and TGF-beta-induced fibrogenesis in human colonic myofibroblasts
    • Johnson L.A., Rodansky E.S., Haak A.J., Larsen S.D., Neubig R.R., Higgins P.D. Novel Rho/MRTF/SRF inhibitors block matrix-stiffness and TGF-beta-induced fibrogenesis in human colonic myofibroblasts. Inflamm. Bowel Dis. 2014, 20:154-165.
    • (2014) Inflamm. Bowel Dis. , vol.20 , pp. 154-165
    • Johnson, L.A.1    Rodansky, E.S.2    Haak, A.J.3    Larsen, S.D.4    Neubig, R.R.5    Higgins, P.D.6
  • 168
    • 82455198983 scopus 로고    scopus 로고
    • Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets
    • Jun J.I., Lau L.F. Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets. Nat. Rev. Drug Discov. 2011, 10:945-963.
    • (2011) Nat. Rev. Drug Discov. , vol.10 , pp. 945-963
    • Jun, J.I.1    Lau, L.F.2
  • 169
    • 0027973699 scopus 로고
    • Lysyl oxidase: mechanism, regulation and relationship to liver fibrosis
    • Kagan H.M. Lysyl oxidase: mechanism, regulation and relationship to liver fibrosis. Pathol. Res. Pract. 1994, 190:910-919.
    • (1994) Pathol. Res. Pract. , vol.190 , pp. 910-919
    • Kagan, H.M.1
  • 170
    • 84903767326 scopus 로고    scopus 로고
    • Can we safely target the Wnt pathway?
    • Kahn M. Can we safely target the Wnt pathway?. Nat. Rev. Drug Discov. 2014, 13:513-532.
    • (2014) Nat. Rev. Drug Discov. , vol.13 , pp. 513-532
    • Kahn, M.1
  • 171
    • 33645037848 scopus 로고    scopus 로고
    • Novel functions of intracellular IL-1ra in human dermal Fibroblasts: Implications in the pathogenesis of fibrosis
    • Kanangat S., Postlethwaite A.E., Higgins G.C., Hasty K.A. Novel functions of intracellular IL-1ra in human dermal Fibroblasts: Implications in the pathogenesis of fibrosis. J. Investig. Dermatol. 2006, 126:756-765.
    • (2006) J. Investig. Dermatol. , vol.126 , pp. 756-765
    • Kanangat, S.1    Postlethwaite, A.E.2    Higgins, G.C.3    Hasty, K.A.4
  • 172
    • 79960559043 scopus 로고    scopus 로고
    • Transforming growth factor-beta3 regulates assembly of a non-fibrotic matrix in a 3D corneal model
    • Karamichos D., Hutcheon A.E., Zieske J.D. Transforming growth factor-beta3 regulates assembly of a non-fibrotic matrix in a 3D corneal model. J. Tissue Eng. Regen. Med. 2011, 5:e228-238.
    • (2011) J. Tissue Eng. Regen. Med. , vol.5 , pp. e228-238
    • Karamichos, D.1    Hutcheon, A.E.2    Zieske, J.D.3
  • 173
    • 84901506615 scopus 로고    scopus 로고
    • Reversal of fibrosis by TGF-beta3 in a 3D in vitro model
    • Karamichos D., Hutcheon A.E., Zieske J.D. Reversal of fibrosis by TGF-beta3 in a 3D in vitro model. Exp. Eye Res. 2014, 124:31-36.
    • (2014) Exp. Eye Res. , vol.124 , pp. 31-36
    • Karamichos, D.1    Hutcheon, A.E.2    Zieske, J.D.3
  • 174
    • 38449099430 scopus 로고    scopus 로고
    • Regulation of corneal fibroblast morphology and collagen reorganization by extracellular matrix mechanical properties
    • Karamichos D., Lakshman N., Petroll W.M. Regulation of corneal fibroblast morphology and collagen reorganization by extracellular matrix mechanical properties. Investig. Ophthalmol. Vis. Sci. 2007, 48:5030-5037.
    • (2007) Investig. Ophthalmol. Vis. Sci. , vol.48 , pp. 5030-5037
    • Karamichos, D.1    Lakshman, N.2    Petroll, W.M.3
  • 175
    • 67650456233 scopus 로고    scopus 로고
    • Corneal myofibroblast viability: opposing effects of IL-1 and TGF beta1
    • Kaur H., Chaurasia S.S., Agrawal V., Suto C., Wilson S.E. Corneal myofibroblast viability: opposing effects of IL-1 and TGF beta1. Exp. Eye Res. 2009, 89:152-158.
    • (2009) Exp. Eye Res. , vol.89 , pp. 152-158
    • Kaur, H.1    Chaurasia, S.S.2    Agrawal, V.3    Suto, C.4    Wilson, S.E.5
  • 177
    • 25144508289 scopus 로고    scopus 로고
    • Intrastromal invasion by limbal epithelial cells is mediated by epithelial-mesenchymal transition activated by air exposure
    • Kawakita T., Espana E.M., He H., Li W., Liu C.Y., Tseng S.C. Intrastromal invasion by limbal epithelial cells is mediated by epithelial-mesenchymal transition activated by air exposure. Am. J. Pathol. 2005, 167:381-393.
    • (2005) Am. J. Pathol. , vol.167 , pp. 381-393
    • Kawakita, T.1    Espana, E.M.2    He, H.3    Li, W.4    Liu, C.Y.5    Tseng, S.C.6
  • 178
    • 84867186245 scopus 로고    scopus 로고
    • Activation of Smad-mediated TGF-beta signaling triggers epithelial-mesenchymal transitions in murine cloned corneal progenitor cells
    • Kawakita T., Espana E.M., Higa K., Kato N., Li W., Tseng S.C. Activation of Smad-mediated TGF-beta signaling triggers epithelial-mesenchymal transitions in murine cloned corneal progenitor cells. J. Cell Physiol. 2013, 228:225-234.
    • (2013) J. Cell Physiol. , vol.228 , pp. 225-234
    • Kawakita, T.1    Espana, E.M.2    Higa, K.3    Kato, N.4    Li, W.5    Tseng, S.C.6
  • 180
    • 30444445269 scopus 로고    scopus 로고
    • Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells
    • Kirwan R.P., Leonard M.O., Murphy M., Clark A.F., O'Brien C.J. Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells. Glia 2005, 52:309-324.
    • (2005) Glia , vol.52 , pp. 309-324
    • Kirwan, R.P.1    Leonard, M.O.2    Murphy, M.3    Clark, A.F.4    O'Brien, C.J.5
  • 181
    • 79955120145 scopus 로고    scopus 로고
    • Is it the end of the line for the EMT?
    • Kisseleva T., Brenner D.A. Is it the end of the line for the EMT?. Hepatology 2011, 53:1433-1435.
    • (2011) Hepatology , vol.53 , pp. 1433-1435
    • Kisseleva, T.1    Brenner, D.A.2
  • 184
    • 84871046283 scopus 로고    scopus 로고
    • The myofibroblast matrix: implications for tissue repair and fibrosis
    • Klingberg F., Hinz B., White E.S. The myofibroblast matrix: implications for tissue repair and fibrosis. J. Pathol. 2013, 229:298-309.
    • (2013) J. Pathol. , vol.229 , pp. 298-309
    • Klingberg, F.1    Hinz, B.2    White, E.S.3
  • 191
    • 84883293187 scopus 로고    scopus 로고
    • Mechanisms for PDGF, a serum cytokine, stimulating loss of corneal keratocyte crystallins
    • LaGier A.J., Gordon G.M., Katzman L.R., Vasiliou V., Fini M.E. Mechanisms for PDGF, a serum cytokine, stimulating loss of corneal keratocyte crystallins. Cornea 2013, 32:1269-1275.
    • (2013) Cornea , vol.32 , pp. 1269-1275
    • LaGier, A.J.1    Gordon, G.M.2    Katzman, L.R.3    Vasiliou, V.4    Fini, M.E.5
  • 193
    • 21544440606 scopus 로고    scopus 로고
    • Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys
    • Le Hir M., Hegyi I., Cueni-Loffing D., Loffing J., Kaissling B. Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys. Histochem Cell Biol. 2005, 123:335-346.
    • (2005) Histochem Cell Biol. , vol.123 , pp. 335-346
    • Le Hir, M.1    Hegyi, I.2    Cueni-Loffing, D.3    Loffing, J.4    Kaissling, B.5
  • 194
    • 77953808712 scopus 로고    scopus 로고
    • Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation
    • Leask A. Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation. Circ. Res. 2010, 106:1675-1680.
    • (2010) Circ. Res. , vol.106 , pp. 1675-1680
    • Leask, A.1
  • 195
    • 73549104820 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?
    • Leask A., Parapuram S.K., Shi-Wen X., Abraham D.J. Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?. J. Cell Commun. Signal 2009, 3:89-94.
    • (2009) J. Cell Commun. Signal , vol.3 , pp. 89-94
    • Leask, A.1    Parapuram, S.K.2    Shi-Wen, X.3    Abraham, D.J.4
  • 196
    • 81155123597 scopus 로고    scopus 로고
    • Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis
    • LeBleu V.S., Kalluri R. Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis. Kidney Int. 2011, 80:1119-1121.
    • (2011) Kidney Int. , vol.80 , pp. 1119-1121
    • LeBleu, V.S.1    Kalluri, R.2
  • 197
    • 84863229849 scopus 로고    scopus 로고
    • Matrix rigidity regulates a switch between TGF-beta1-induced apoptosis and epithelial-mesenchymal transition
    • Leight J.L., Wozniak M.A., Chen S., Lynch M.L., Chen C.S. Matrix rigidity regulates a switch between TGF-beta1-induced apoptosis and epithelial-mesenchymal transition. Mol. Biol. Cell 2012, 23:781-791.
    • (2012) Mol. Biol. Cell , vol.23 , pp. 781-791
    • Leight, J.L.1    Wozniak, M.A.2    Chen, S.3    Lynch, M.L.4    Chen, C.S.5
  • 198
    • 0032867875 scopus 로고    scopus 로고
    • Differential expression and regulation of TGF-beta1, TGF-beta2, TGF-beta3, TGF-betaRI, TGF-betaRII and TGF-betaRIII in cultured human corneal, limbal, and conjunctival fibroblasts
    • Li D.Q., Lee S.B., Tseng S.C. Differential expression and regulation of TGF-beta1, TGF-beta2, TGF-beta3, TGF-betaRI, TGF-betaRII and TGF-betaRIII in cultured human corneal, limbal, and conjunctival fibroblasts. Curr. Eye Res. 1999, 19:154-161.
    • (1999) Curr. Eye Res. , vol.19 , pp. 154-161
    • Li, D.Q.1    Lee, S.B.2    Tseng, S.C.3
  • 199
    • 84876166389 scopus 로고    scopus 로고
    • Macrophage depletion impairs corneal wound healing after autologous transplantation in mice
    • Li S., Li B., Jiang H., Wang Y., Qu M., Duan H., Zhou Q., Shi W. Macrophage depletion impairs corneal wound healing after autologous transplantation in mice. PLoS One 2013, 8:e61799.
    • (2013) PLoS One , vol.8 , pp. e61799
    • Li, S.1    Li, B.2    Jiang, H.3    Wang, Y.4    Qu, M.5    Duan, H.6    Zhou, Q.7    Shi, W.8
  • 203
    • 84859922148 scopus 로고    scopus 로고
    • Micro-mechanical characterization of lung tissue using atomic force microscopy
    • Liu F., Tschumperlin D.J. Micro-mechanical characterization of lung tissue using atomic force microscopy. J. Vis. Exp. 2011, 54.
    • (2011) J. Vis. Exp. , vol.54
    • Liu, F.1    Tschumperlin, D.J.2
  • 204
    • 0028278794 scopus 로고
    • Induction of cataract-like changes in rat lens epithelial explants by transforming growth factor beta
    • Liu J., Hales A.M., Chamberlain C.G., McAvoy J.W. Induction of cataract-like changes in rat lens epithelial explants by transforming growth factor beta. Investig. Ophthalmol. Vis. Sci. 1994, 35:388-401.
    • (1994) Investig. Ophthalmol. Vis. Sci. , vol.35 , pp. 388-401
    • Liu, J.1    Hales, A.M.2    Chamberlain, C.G.3    McAvoy, J.W.4
  • 205
    • 78650798178 scopus 로고    scopus 로고
    • CCN2 is required for bleomycin-induced skin fibrosis in mice
    • Liu S., Shi-wen X., Abraham D.J., Leask A. CCN2 is required for bleomycin-induced skin fibrosis in mice. Arthritis Rheum. 2011, 63:239-246.
    • (2011) Arthritis Rheum. , vol.63 , pp. 239-246
    • Liu, S.1    Shi-wen, X.2    Abraham, D.J.3    Leask, A.4
  • 207
    • 84961566095 scopus 로고    scopus 로고
    • Fibrosis in the lens. Sprouty regulation of TGFbeta-signaling prevents lens EMT leading to cataract
    • [e-pub ahead of print]
    • Lovicu F.J., Shin E.H., McAvoy J.W. Fibrosis in the lens. Sprouty regulation of TGFbeta-signaling prevents lens EMT leading to cataract. Exp. Eye Res. 2015, [e-pub ahead of print].
    • (2015) Exp. Eye Res.
    • Lovicu, F.J.1    Shin, E.H.2    McAvoy, J.W.3
  • 208
    • 84859949610 scopus 로고    scopus 로고
    • The extracellular matrix: a dynamic niche in cancer progression
    • Lu P., Weaver V.M., Werb Z. The extracellular matrix: a dynamic niche in cancer progression. J. Cell Biol. 2012, 196:395-406.
    • (2012) J. Cell Biol. , vol.196 , pp. 395-406
    • Lu, P.1    Weaver, V.M.2    Werb, Z.3
  • 210
    • 83755162557 scopus 로고    scopus 로고
    • Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts
    • Luchsinger L.L., Patenaude C.A., Smith B.D., Layne M.D. Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts. J. Biol. Chem. 2011, 286:44116-44125.
    • (2011) J. Biol. Chem. , vol.286 , pp. 44116-44125
    • Luchsinger, L.L.1    Patenaude, C.A.2    Smith, B.D.3    Layne, M.D.4
  • 211
    • 19644367664 scopus 로고    scopus 로고
    • Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering
    • Lutolf M.P., Hubbell J.A. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat. Biotechnol. 2005, 23:47-55.
    • (2005) Nat. Biotechnol. , vol.23 , pp. 47-55
    • Lutolf, M.P.1    Hubbell, J.A.2
  • 212
    • 59849120889 scopus 로고    scopus 로고
    • A novel method of dynamic culture surface expansion improves mesenchymal stem cell proliferation and phenotype
    • Majd H., Wipff P.J., Buscemi L., Bueno M., Vonwil D., Quinn T.M., Hinz B. A novel method of dynamic culture surface expansion improves mesenchymal stem cell proliferation and phenotype. Stem Cells 2009, 27:200-209.
    • (2009) Stem Cells , vol.27 , pp. 200-209
    • Majd, H.1    Wipff, P.J.2    Buscemi, L.3    Bueno, M.4    Vonwil, D.5    Quinn, T.M.6    Hinz, B.7
  • 213
    • 84870850060 scopus 로고    scopus 로고
    • Cardiomyocytes from late embryos and neonates do optimal work and striate best on substrates with tissue-level elasticity: metrics and mathematics
    • Majkut S.F., Discher D.E. Cardiomyocytes from late embryos and neonates do optimal work and striate best on substrates with tissue-level elasticity: metrics and mathematics. Biomech. Model Mechanobiol. 2012, 11:1219-1225.
    • (2012) Biomech. Model Mechanobiol. , vol.11 , pp. 1219-1225
    • Majkut, S.F.1    Discher, D.E.2
  • 216
    • 84871076444 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization in tissue repair and remodelling
    • Mantovani A., Biswas S.K., Galdiero M.R., Sica A., Locati M. Macrophage plasticity and polarization in tissue repair and remodelling. J. Pathol. 2013, 229:176-185.
    • (2013) J. Pathol. , vol.229 , pp. 176-185
    • Mantovani, A.1    Biswas, S.K.2    Galdiero, M.R.3    Sica, A.4    Locati, M.5
  • 217
    • 75949103899 scopus 로고    scopus 로고
    • Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing
    • Margadant C., Sonnenberg A. Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing. EMBO Rep. 2010, 11:97-105.
    • (2010) EMBO Rep. , vol.11 , pp. 97-105
    • Margadant, C.1    Sonnenberg, A.2
  • 218
    • 84878222372 scopus 로고    scopus 로고
    • Matrices of physiologic stiffness potently inactivate idiopathic pulmonary fibrosis fibroblasts
    • Marinkovic A., Liu F., Tschumperlin D.J. Matrices of physiologic stiffness potently inactivate idiopathic pulmonary fibrosis fibroblasts. Am. J. Respir. Cell Mol. Biol. 2013, 48:422-430.
    • (2013) Am. J. Respir. Cell Mol. Biol. , vol.48 , pp. 422-430
    • Marinkovic, A.1    Liu, F.2    Tschumperlin, D.J.3
  • 219
    • 84864744748 scopus 로고    scopus 로고
    • Improved throughput traction microscopy reveals pivotal role for matrix stiffness in fibroblast contractility and TGF-beta responsiveness
    • Marinkovic A., Mih J.D., Park J.A., Liu F., Tschumperlin D.J. Improved throughput traction microscopy reveals pivotal role for matrix stiffness in fibroblast contractility and TGF-beta responsiveness. Am. J. Physiol. Lung Cell Mol. Physiol. 2012, 303:L169-L180.
    • (2012) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.303 , pp. L169-L180
    • Marinkovic, A.1    Mih, J.D.2    Park, J.A.3    Liu, F.4    Tschumperlin, D.J.5
  • 220
    • 27744543102 scopus 로고    scopus 로고
    • Inflammatory cells during wound repair: the good, the bad and the ugly
    • Martin P., Leibovich S.J. Inflammatory cells during wound repair: the good, the bad and the ugly. Trends Cell Biol. 2005, 15:599-607.
    • (2005) Trends Cell Biol. , vol.15 , pp. 599-607
    • Martin, P.1    Leibovich, S.J.2
  • 221
    • 84897556094 scopus 로고    scopus 로고
    • The M1 and M2 paradigm of macrophage activation: time for reassessment
    • Martinez F.O., Gordon S. The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000 Prime Rep. 2014, 6:13.
    • (2014) F1000 Prime Rep. , vol.6 , pp. 13
    • Martinez, F.O.1    Gordon, S.2
  • 222
    • 76349084499 scopus 로고    scopus 로고
    • Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3
    • Masszi A., Speight P., Charbonney E., Lodyga M., Nakano H., Szaszi K., Kapus A. Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3. J. Cell Biol. 2010, 188:383-399.
    • (2010) J. Cell Biol. , vol.188 , pp. 383-399
    • Masszi, A.1    Speight, P.2    Charbonney, E.3    Lodyga, M.4    Nakano, H.5    Szaszi, K.6    Kapus, A.7
  • 225
    • 80055056452 scopus 로고    scopus 로고
    • Localization of thrombospondin-1 and myofibroblasts during corneal wound repair
    • Matsuba M., Hutcheon A.E., Zieske J.D. Localization of thrombospondin-1 and myofibroblasts during corneal wound repair. Exp. Eye Res. 2011, 93:534-540.
    • (2011) Exp. Eye Res. , vol.93 , pp. 534-540
    • Matsuba, M.1    Hutcheon, A.E.2    Zieske, J.D.3
  • 227
    • 84857072845 scopus 로고    scopus 로고
    • Extracellular matrix elasticity modulates TGF-beta-induced p38 activation and myofibroblast transdifferentiation in human tenon fibroblasts
    • Meyer-ter-Vehn T., Han H., Grehn F., Schlunck G. Extracellular matrix elasticity modulates TGF-beta-induced p38 activation and myofibroblast transdifferentiation in human tenon fibroblasts. Investig. Ophthalmol. Vis. Sci. 2011, 52:9149-9155.
    • (2011) Investig. Ophthalmol. Vis. Sci. , vol.52 , pp. 9149-9155
    • Meyer-ter-Vehn, T.1    Han, H.2    Grehn, F.3    Schlunck, G.4
  • 230
    • 73549118560 scopus 로고    scopus 로고
    • Selective and specific macrophage ablation is detrimental to wound healing in mice
    • Mirza R., DiPietro L.A., Koh T.J. Selective and specific macrophage ablation is detrimental to wound healing in mice. Am. J. Pathol. 2009, 175:2454-2462.
    • (2009) Am. J. Pathol. , vol.175 , pp. 2454-2462
    • Mirza, R.1    DiPietro, L.A.2    Koh, T.J.3
  • 233
    • 0031595120 scopus 로고    scopus 로고
    • Neutralizing antibody to TGFbeta modulates stromal fibrosis but not regression of photoablative effect following PRK
    • Moller-Pedersen T., Cavanagh H.D., Petroll W.M., Jester J.V. Neutralizing antibody to TGFbeta modulates stromal fibrosis but not regression of photoablative effect following PRK. Curr. Eye Res. 1998, 17:736-747.
    • (1998) Curr. Eye Res. , vol.17 , pp. 736-747
    • Moller-Pedersen, T.1    Cavanagh, H.D.2    Petroll, W.M.3    Jester, J.V.4
  • 234
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser D.M., Edwards J.P. Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 2008, 8:958-969.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 235
  • 237
    • 72749116727 scopus 로고    scopus 로고
    • Meet the corneal myofibroblast: the role of myofibroblast transformation in corneal wound healing and pathology
    • Myrna K.E., Pot S.A., Murphy C.J. Meet the corneal myofibroblast: the role of myofibroblast transformation in corneal wound healing and pathology. Vet. Ophthalmol. 2009, 12(Suppl. 1):25-27.
    • (2009) Vet. Ophthalmol. , vol.12 , pp. 25-27
    • Myrna, K.E.1    Pot, S.A.2    Murphy, C.J.3
  • 238
    • 0141652015 scopus 로고    scopus 로고
    • Interaction between injured corneal epithelial cells and stromal cells
    • Nakamura K. Interaction between injured corneal epithelial cells and stromal cells. Cornea 2003, 22:S35-S47.
    • (2003) Cornea , vol.22 , pp. S35-S47
    • Nakamura, K.1
  • 240
    • 39549089570 scopus 로고    scopus 로고
    • Connexin43 knockdown accelerates wound healing but inhibits mesenchymal transition after corneal endothelial injury in vivo
    • Nakano Y., Oyamada M., Dai P., Nakagami T., Kinoshita S., Takamatsu T. Connexin43 knockdown accelerates wound healing but inhibits mesenchymal transition after corneal endothelial injury in vivo. Investig. Ophthalmol. Vis. Sci. 2008, 49:93-104.
    • (2008) Investig. Ophthalmol. Vis. Sci. , vol.49 , pp. 93-104
    • Nakano, Y.1    Oyamada, M.2    Dai, P.3    Nakagami, T.4    Kinoshita, S.5    Takamatsu, T.6
  • 241
    • 0025068931 scopus 로고
    • Transforming growth factor-beta and its actions on cellular growth and differentiation
    • Nilsen-Hamilton M. Transforming growth factor-beta and its actions on cellular growth and differentiation. Curr. Top. Dev. Biol. 1990, 24:95-136.
    • (1990) Curr. Top. Dev. Biol. , vol.24 , pp. 95-136
    • Nilsen-Hamilton, M.1
  • 242
    • 0030043897 scopus 로고    scopus 로고
    • Effects of the cytokines on the proliferation of and collagen synthesis by human cataract lens epithelial cells
    • Nishi O., Nishi K., Fujiwara T., Shirasawa E., Ohmoto Y. Effects of the cytokines on the proliferation of and collagen synthesis by human cataract lens epithelial cells. Br. J. Ophthalmol. 1996, 80:63-68.
    • (1996) Br. J. Ophthalmol. , vol.80 , pp. 63-68
    • Nishi, O.1    Nishi, K.2    Fujiwara, T.3    Shirasawa, E.4    Ohmoto, Y.5
  • 243
  • 245
    • 84928380459 scopus 로고    scopus 로고
    • Matrix rigidity mediates TGFbeta1-induced epithelial-myofibroblast transition by controlling cytoskeletal organization and MRTF-A localization
    • O'Connor J.W., Riley P.N., Nalluri S.M., Ashar P.K., Gomez E.W. Matrix rigidity mediates TGFbeta1-induced epithelial-myofibroblast transition by controlling cytoskeletal organization and MRTF-A localization. J. Cell Physiol. 2014, 230:1829-1839.
    • (2014) J. Cell Physiol. , vol.230 , pp. 1829-1839
    • O'Connor, J.W.1    Riley, P.N.2    Nalluri, S.M.3    Ashar, P.K.4    Gomez, E.W.5
  • 247
    • 84874363905 scopus 로고    scopus 로고
    • Inhibition of TGF-beta signaling enables human corneal endothelial cell expansion in vitro for use in regenerative medicine
    • Okumura N., Kay E.P., Nakahara M., Hamuro J., Kinoshita S., Koizumi N. Inhibition of TGF-beta signaling enables human corneal endothelial cell expansion in vitro for use in regenerative medicine. PLoS One 2013, 8:e58000.
    • (2013) PLoS One , vol.8 , pp. e58000
    • Okumura, N.1    Kay, E.P.2    Nakahara, M.3    Hamuro, J.4    Kinoshita, S.5    Koizumi, N.6
  • 250
    • 59649093844 scopus 로고    scopus 로고
    • Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis
    • Olson L.E., Soriano P. Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis. Dev. Cell 2009, 16:303-313.
    • (2009) Dev. Cell , vol.16 , pp. 303-313
    • Olson, L.E.1    Soriano, P.2
  • 252
    • 0031918208 scopus 로고    scopus 로고
    • Effects of gamma-interferon on keratocyte-induced collagen gel contraction and keratocyte proliferation
    • Pakkar A., Rofougaran R., Lu K., Wee W.R., Isfahani A.K., McDonnell P.J. Effects of gamma-interferon on keratocyte-induced collagen gel contraction and keratocyte proliferation. J. Refract Surg. 1998, 14:152-155.
    • (1998) J. Refract Surg. , vol.14 , pp. 152-155
    • Pakkar, A.1    Rofougaran, R.2    Lu, K.3    Wee, W.R.4    Isfahani, A.K.5    McDonnell, P.J.6
  • 253
    • 0142139197 scopus 로고    scopus 로고
    • FGF-2 antagonizes the TGF-beta1-mediated induction of pericyte alpha-smooth muscle actin expression: a role for myf-5 and Smad-mediated signaling pathways
    • Papetti M., Shujath J., Riley K.N., Herman I.M. FGF-2 antagonizes the TGF-beta1-mediated induction of pericyte alpha-smooth muscle actin expression: a role for myf-5 and Smad-mediated signaling pathways. Investig. Ophthalmol. Vis. Sci. 2003, 44:4994-5005.
    • (2003) Investig. Ophthalmol. Vis. Sci. , vol.44 , pp. 4994-5005
    • Papetti, M.1    Shujath, J.2    Riley, K.N.3    Herman, I.M.4
  • 255
    • 84878256553 scopus 로고    scopus 로고
    • VEGF induces TGF-beta1 expression and myofibroblast transformation after glaucoma surgery
    • Park H.Y., Kim J.H., Park C.K. VEGF induces TGF-beta1 expression and myofibroblast transformation after glaucoma surgery. Am. J. Pathol. 2013, 182:2147-2154.
    • (2013) Am. J. Pathol. , vol.182 , pp. 2147-2154
    • Park, H.Y.1    Kim, J.H.2    Park, C.K.3
  • 256
    • 79953025653 scopus 로고    scopus 로고
    • The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-beta
    • Park J.S., Chu J.S., Tsou A.D., Diop R., Tang Z., Wang A., Li S. The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-beta. Biomaterials 2011, 32:3921-3930.
    • (2011) Biomaterials , vol.32 , pp. 3921-3930
    • Park, J.S.1    Chu, J.S.2    Tsou, A.D.3    Diop, R.4    Tang, Z.5    Wang, A.6    Li, S.7
  • 258
    • 84896538885 scopus 로고    scopus 로고
    • Regulation of plasticity and fibrogenic activity of trabecular meshwork cells by Rho GTPase signaling
    • Pattabiraman P.P., Maddala R., Rao P.V. Regulation of plasticity and fibrogenic activity of trabecular meshwork cells by Rho GTPase signaling. J. Cell Physiol. 2014, 229:927-942.
    • (2014) J. Cell Physiol. , vol.229 , pp. 927-942
    • Pattabiraman, P.P.1    Maddala, R.2    Rao, P.V.3
  • 259
    • 7044274497 scopus 로고    scopus 로고
    • Thy-1 distinguishes human corneal fibroblasts and myofibroblasts from keratocytes
    • Pei Y., Sherry D.M., McDermott A.M. Thy-1 distinguishes human corneal fibroblasts and myofibroblasts from keratocytes. Exp. Eye Res. 2004, 79:705-712.
    • (2004) Exp. Eye Res. , vol.79 , pp. 705-712
    • Pei, Y.1    Sherry, D.M.2    McDermott, A.M.3
  • 260
    • 84902455478 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibits alpha-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A
    • Penke L.R., Huang S.K., White E.S., Peters-Golden M. Prostaglandin E2 inhibits alpha-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A. J. Biol. Chem. 2014, 289:17151-17162.
    • (2014) J. Biol. Chem. , vol.289 , pp. 17151-17162
    • Penke, L.R.1    Huang, S.K.2    White, E.S.3    Peters-Golden, M.4
  • 263
    • 0031690824 scopus 로고    scopus 로고
    • Myofibroblast transformation of cat corneal endothelium by transforming growth factor-beta1, -beta2, and -beta3
    • Petroll W.M., Jester J.V., Bean J.J., Cavanagh H.D. Myofibroblast transformation of cat corneal endothelium by transforming growth factor-beta1, -beta2, and -beta3. Investig. Ophthalmol. Vis. Sci. 1998, 39:2018-2032.
    • (1998) Investig. Ophthalmol. Vis. Sci. , vol.39 , pp. 2018-2032
    • Petroll, W.M.1    Jester, J.V.2    Bean, J.J.3    Cavanagh, H.D.4
  • 264
    • 84961643337 scopus 로고    scopus 로고
    • Fibroblastic transformation of corneal keratocytes by Rac inhibition is modulated by extracellular matrix structure and stiffness
    • Petroll W.M., Lakshman N. Fibroblastic transformation of corneal keratocytes by Rac inhibition is modulated by extracellular matrix structure and stiffness. J. Funct. Biomater. 2015, 6:222-240.
    • (2015) J. Funct. Biomater. , vol.6 , pp. 222-240
    • Petroll, W.M.1    Lakshman, N.2
  • 265
    • 84925382251 scopus 로고    scopus 로고
    • Mechanical interactions and crosstalk between corneal keratocytes and the extracellular matrix
    • Petroll W.M., Miron-Mendoza M. Mechanical interactions and crosstalk between corneal keratocytes and the extracellular matrix. Exp. Eye Res. 2015, 133:49-57.
    • (2015) Exp. Eye Res. , vol.133 , pp. 49-57
    • Petroll, W.M.1    Miron-Mendoza, M.2
  • 266
    • 70849136597 scopus 로고    scopus 로고
    • Connective tissue growth factor-(CTGF, CCN2)-a marker, mediator and therapeutic target for renal fibrosis
    • Phanish M.K., Winn S.K., Dockrell M.E. Connective tissue growth factor-(CTGF, CCN2)-a marker, mediator and therapeutic target for renal fibrosis. Nephron. Exp. Nephrol. 2010, 114:e83-92.
    • (2010) Nephron. Exp. Nephrol. , vol.114 , pp. e83-92
    • Phanish, M.K.1    Winn, S.K.2    Dockrell, M.E.3
  • 267
    • 84915763166 scopus 로고    scopus 로고
    • The extracellular matrix modulates the hallmarks of cancer
    • Pickup M.W., Mouw J.K., Weaver V.M. The extracellular matrix modulates the hallmarks of cancer. EMBO Rep. 2014, 15:1243-1253.
    • (2014) EMBO Rep. , vol.15 , pp. 1243-1253
    • Pickup, M.W.1    Mouw, J.K.2    Weaver, V.M.3
  • 268
    • 77949884327 scopus 로고    scopus 로고
    • Nanoscale topography-induced modulation of fundamental cell behaviors of rabbit corneal keratocytes, fibroblasts, and myofibroblasts
    • Pot S.A., Liliensiek S.J., Myrna K.E., Bentley E., Jester J.V., Nealey P.F., Murphy C.J. Nanoscale topography-induced modulation of fundamental cell behaviors of rabbit corneal keratocytes, fibroblasts, and myofibroblasts. Investig. Ophthalmol. Vis. Sci. 2010, 51:1373-1381.
    • (2010) Investig. Ophthalmol. Vis. Sci. , vol.51 , pp. 1373-1381
    • Pot, S.A.1    Liliensiek, S.J.2    Myrna, K.E.3    Bentley, E.4    Jester, J.V.5    Nealey, P.F.6    Murphy, C.J.7
  • 270
    • 79958779687 scopus 로고    scopus 로고
    • Scar wars: mapping the fate of epithelial-mesenchymal-myofibroblast transition
    • Quaggin S.E., Kapus A. Scar wars: mapping the fate of epithelial-mesenchymal-myofibroblast transition. Kidney Int. 2011, 80:41-50.
    • (2011) Kidney Int. , vol.80 , pp. 41-50
    • Quaggin, S.E.1    Kapus, A.2
  • 271
    • 84864405708 scopus 로고    scopus 로고
    • Investigating the role of substrate stiffness in the persistence of valvular interstitial cell activation
    • Quinlan A.M., Billiar K.L. Investigating the role of substrate stiffness in the persistence of valvular interstitial cell activation. J. Biomed. Mater Res. A 2012, 100:2474-2482.
    • (2012) J. Biomed. Mater Res. A , vol.100 , pp. 2474-2482
    • Quinlan, A.M.1    Billiar, K.L.2
  • 273
    • 34447250376 scopus 로고    scopus 로고
    • Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT?
    • Radisky D.C., Kenny P.A., Bissell M.J. Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT?. J. Cell Biochem. 2007, 101:830-839.
    • (2007) J. Cell Biochem. , vol.101 , pp. 830-839
    • Radisky, D.C.1    Kenny, P.A.2    Bissell, M.J.3
  • 276
    • 70349325817 scopus 로고    scopus 로고
    • Extracellular microfibrils: contextual platforms for TGFbeta and BMP signaling
    • Ramirez F., Rifkin D.B. Extracellular microfibrils: contextual platforms for TGFbeta and BMP signaling. Curr. Opin. Cell Biol. 2009, 21:616-622.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 616-622
    • Ramirez, F.1    Rifkin, D.B.2
  • 278
    • 84883820451 scopus 로고    scopus 로고
    • Unchaining the beast; insights from structural and evolutionary studies on TGFbeta secretion, sequestration, and activation
    • Robertson I.B., Rifkin D.B. Unchaining the beast; insights from structural and evolutionary studies on TGFbeta secretion, sequestration, and activation. Cytokine Growth Factor Rev. 2013, 24:355-372.
    • (2013) Cytokine Growth Factor Rev. , vol.24 , pp. 355-372
    • Robertson, I.B.1    Rifkin, D.B.2
  • 279
    • 0026782189 scopus 로고
    • Inhibition of rat hepatic lipocyte activation in culture by interferon- gamma
    • Rockey D.C., Maher J.J., Jarnagin W.R., Gabbiani G., Friedman S.L. Inhibition of rat hepatic lipocyte activation in culture by interferon- gamma. Hepatology 1992, 16:776-784.
    • (1992) Hepatology , vol.16 , pp. 776-784
    • Rockey, D.C.1    Maher, J.J.2    Jarnagin, W.R.3    Gabbiani, G.4    Friedman, S.L.5
  • 280
    • 0027161705 scopus 로고
    • Induction of alpha-smooth muscle actin by transforming growth factor-beta 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia
    • Rønnov-Jessen L., Petersen O.W. Induction of alpha-smooth muscle actin by transforming growth factor-beta 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia. Lab. Investig. 1993, 68:696-707.
    • (1993) Lab. Investig. , vol.68 , pp. 696-707
    • Rønnov-Jessen, L.1    Petersen, O.W.2
  • 281
    • 0030011880 scopus 로고    scopus 로고
    • A function for filamentous alpha-smooth muscle actin: retardation of motility in fibroblasts
    • Rønnov-Jessen L., Petersen O.W. A function for filamentous alpha-smooth muscle actin: retardation of motility in fibroblasts. J. Cell Biol. 1996, 134:67-80.
    • (1996) J. Cell Biol. , vol.134 , pp. 67-80
    • Rønnov-Jessen, L.1    Petersen, O.W.2
  • 285
    • 0034740034 scopus 로고    scopus 로고
    • Latent TGFbeta binding protein-1 and fibrillin-1 in human capsular opacification and in cultured lens epithelial cells
    • Saika S., Miyamoto T., Tanaka T., Ishida I., Ohnishi Y., Ooshima A. Latent TGFbeta binding protein-1 and fibrillin-1 in human capsular opacification and in cultured lens epithelial cells. Br. J. Ophthalmol. 2001, 85:1362-1366.
    • (2001) Br. J. Ophthalmol. , vol.85 , pp. 1362-1366
    • Saika, S.1    Miyamoto, T.2    Tanaka, T.3    Ishida, I.4    Ohnishi, Y.5    Ooshima, A.6
  • 288
    • 81355160563 scopus 로고    scopus 로고
    • Monocyte development inhibitor PRM-151 decreases corneal myofibroblast generation in rabbits
    • Santhiago M.R., Singh V., Barbosa F.L., Agrawal V., Wilson S.E. Monocyte development inhibitor PRM-151 decreases corneal myofibroblast generation in rabbits. Exp. Eye Res. 2011, 93:786-789.
    • (2011) Exp. Eye Res. , vol.93 , pp. 786-789
    • Santhiago, M.R.1    Singh, V.2    Barbosa, F.L.3    Agrawal, V.4    Wilson, S.E.5
  • 289
    • 84901440560 scopus 로고    scopus 로고
    • Integrins alphavbeta5 and alphavbeta3 promote latent TGF-beta1 activation by human cardiac fibroblast contraction
    • Sarrazy V., Koehler A., Chow M.L., Zimina E., Li C.X., Kato H., Caldarone C.A., Hinz B. Integrins alphavbeta5 and alphavbeta3 promote latent TGF-beta1 activation by human cardiac fibroblast contraction. Cardiovasc Res. 2014, 102:407-417.
    • (2014) Cardiovasc Res. , vol.102 , pp. 407-417
    • Sarrazy, V.1    Koehler, A.2    Chow, M.L.3    Zimina, E.4    Li, C.X.5    Kato, H.6    Caldarone, C.A.7    Hinz, B.8
  • 290
    • 84901044572 scopus 로고    scopus 로고
    • Mechanically and chemically tunable cell culture system for studying the myofibroblast phenotype
    • Saums M.K., Wang W., Han B., Madhavan L., Han L., Lee D., Wells R.G. Mechanically and chemically tunable cell culture system for studying the myofibroblast phenotype. Langmuir 2014, 30:5481-5487.
    • (2014) Langmuir , vol.30 , pp. 5481-5487
    • Saums, M.K.1    Wang, W.2    Han, B.3    Madhavan, L.4    Han, L.5    Lee, D.6    Wells, R.G.7
  • 292
    • 0035699088 scopus 로고    scopus 로고
    • Role of transforming growth factor-beta1 and its latent form binding protein in pseudoexfoliation syndrome
    • Schlotzer-Schrehardt U., Zenkel M., Kuchle M., Sakai L.Y., Naumann G.O. Role of transforming growth factor-beta1 and its latent form binding protein in pseudoexfoliation syndrome. Exp. Eye Res. 2001, 73:765-780.
    • (2001) Exp. Eye Res. , vol.73 , pp. 765-780
    • Schlotzer-Schrehardt, U.1    Zenkel, M.2    Kuchle, M.3    Sakai, L.Y.4    Naumann, G.O.5
  • 293
    • 0025335863 scopus 로고
    • Appearance of alpha-smooth muscle actin in human eye lens cells of anterior capsular cataract and in cultured bovine lens-forming cells
    • Schmitt-Graff A., Pau H., Spahr R., Piper H.M., Skalli O., Gabbiani G. Appearance of alpha-smooth muscle actin in human eye lens cells of anterior capsular cataract and in cultured bovine lens-forming cells. Differentiation 1990, 43:115-122.
    • (1990) Differentiation , vol.43 , pp. 115-122
    • Schmitt-Graff, A.1    Pau, H.2    Spahr, R.3    Piper, H.M.4    Skalli, O.5    Gabbiani, G.6
  • 294
    • 84857396328 scopus 로고    scopus 로고
    • Understanding scarring: scarless fetal wound healing as a model
    • Schwartzfarb E., Kirsner R.S. Understanding scarring: scarless fetal wound healing as a model. J. Investig. Dermatol. 2012, 132:260.
    • (2012) J. Investig. Dermatol. , vol.132 , pp. 260
    • Schwartzfarb, E.1    Kirsner, R.S.2
  • 295
    • 18844382639 scopus 로고    scopus 로고
    • Modulation of alpha-smooth muscle actin expression in fibroblasts by transforming growth factor-beta isoforms: an in vivo and in vitro study
    • Serini G., Gabbiani G. Modulation of alpha-smooth muscle actin expression in fibroblasts by transforming growth factor-beta isoforms: an in vivo and in vitro study. Wound Rep. Reg. 1996, 4:278-287.
    • (1996) Wound Rep. Reg. , vol.4 , pp. 278-287
    • Serini, G.1    Gabbiani, G.2
  • 296
    • 0026505458 scopus 로고
    • Control of scarring in adult wounds by neutralising antibody to transforming growth factor beta
    • Shah M., Foreman D.M., Ferguson M.W. Control of scarring in adult wounds by neutralising antibody to transforming growth factor beta. Lancet 1992, 339:213-214.
    • (1992) Lancet , vol.339 , pp. 213-214
    • Shah, M.1    Foreman, D.M.2    Ferguson, M.W.3
  • 297
    • 0028986030 scopus 로고
    • Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring
    • Shah M., Foreman D.M., Ferguson M.W. Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring. J. Cell Sci. 1995, 108(Pt 3):985-1002.
    • (1995) J. Cell Sci. , vol.108 , pp. 985-1002
    • Shah, M.1    Foreman, D.M.2    Ferguson, M.W.3
  • 299
    • 2442707975 scopus 로고    scopus 로고
    • Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1
    • Shephard P., Martin G., Smola-Hess S., Brunner G., Krieg T., Smola H. Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. Am. J. Pathol. 2004, 164:2055-2066.
    • (2004) Am. J. Pathol. , vol.164 , pp. 2055-2066
    • Shephard, P.1    Martin, G.2    Smola-Hess, S.3    Brunner, G.4    Krieg, T.5    Smola, H.6
  • 300
    • 40749107501 scopus 로고    scopus 로고
    • Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis
    • Shi-Wen X., Leask A., Abraham D. Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis. Cytokine Growth Factor Rev. 2008, 19:133-144.
    • (2008) Cytokine Growth Factor Rev. , vol.19 , pp. 133-144
    • Shi-Wen, X.1    Leask, A.2    Abraham, D.3
  • 304
    • 73649131572 scopus 로고    scopus 로고
    • Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation
    • Simpson R.M., Meran S., Thomas D., Stephens P., Bowen T., Steadman R., Phillips A. Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation. Am. J. Pathol. 2009, 175:1915-1928.
    • (2009) Am. J. Pathol. , vol.175 , pp. 1915-1928
    • Simpson, R.M.1    Meran, S.2    Thomas, D.3    Stephens, P.4    Bowen, T.5    Steadman, R.6    Phillips, A.7
  • 305
    • 0022256413 scopus 로고
    • Localization of the fibronexus at the surface of granulation tissue myofibroblasts using double-label immunogold electron microscopy on ultrathin frozen sections
    • Singer I.I., Kazazis D.M., Kawka D.W. Localization of the fibronexus at the surface of granulation tissue myofibroblasts using double-label immunogold electron microscopy on ultrathin frozen sections. Eur. J. Cell Biol. 1985, 38:94-101.
    • (1985) Eur. J. Cell Biol. , vol.38 , pp. 94-101
    • Singer, I.I.1    Kazazis, D.M.2    Kawka, D.W.3
  • 306
    • 84896026207 scopus 로고    scopus 로고
    • TGFbeta and PDGF-B signaling blockade inhibits myofibroblast development from both bone marrow-derived and keratocyte-derived precursor cells in vivo
    • Singh V., Jaini R., Torricelli A.A., Santhiago M.R., Singh N., Ambati B.K., Wilson S.E. TGFbeta and PDGF-B signaling blockade inhibits myofibroblast development from both bone marrow-derived and keratocyte-derived precursor cells in vivo. Exp. Eye Res. 2014, 121:35-40.
    • (2014) Exp. Eye Res. , vol.121 , pp. 35-40
    • Singh, V.1    Jaini, R.2    Torricelli, A.A.3    Santhiago, M.R.4    Singh, N.5    Ambati, B.K.6    Wilson, S.E.7
  • 307
    • 84887370727 scopus 로고    scopus 로고
    • A method to generate enhanced GFP+ chimeric mice to study the role of bone marrow-derived cells in the eye
    • Singh V., Jaini R., Torricelli A.A., Tuohy V.K., Wilson S.E. A method to generate enhanced GFP+ chimeric mice to study the role of bone marrow-derived cells in the eye. Exp. Eye Res. 2013, 116:366-370.
    • (2013) Exp. Eye Res. , vol.116 , pp. 366-370
    • Singh, V.1    Jaini, R.2    Torricelli, A.A.3    Tuohy, V.K.4    Wilson, S.E.5
  • 311
    • 0022881517 scopus 로고
    • A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation
    • Skalli O., Ropraz P., Trzeciak A., Benzonana G., Gillessen D., Gabbiani G. A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J. Cell Biol. 1986, 103:2787-2796.
    • (1986) J. Cell Biol. , vol.103 , pp. 2787-2796
    • Skalli, O.1    Ropraz, P.2    Trzeciak, A.3    Benzonana, G.4    Gillessen, D.5    Gabbiani, G.6
  • 313
    • 34247382146 scopus 로고    scopus 로고
    • Opposite effects of TGF-beta1 and IFN-gamma on transdifferentiation of myofibroblast in human gingival cell cultures
    • Sobral L.M., Montan P.F., Martelli-Junior H., Graner E., Coletta R.D. Opposite effects of TGF-beta1 and IFN-gamma on transdifferentiation of myofibroblast in human gingival cell cultures. J. Clin. Periodontol. 2007, 34:397-406.
    • (2007) J. Clin. Periodontol. , vol.34 , pp. 397-406
    • Sobral, L.M.1    Montan, P.F.2    Martelli-Junior, H.3    Graner, E.4    Coletta, R.D.5
  • 315
    • 84904258110 scopus 로고    scopus 로고
    • TRPV4 channel inhibits TGF-beta1-induced proliferation of hepatic stellate cells
    • Song Y., Zhan L., Yu M., Huang C., Meng X., Ma T., Zhang L., Li J. TRPV4 channel inhibits TGF-beta1-induced proliferation of hepatic stellate cells. PLoS One 2014, 9:e101179.
    • (2014) PLoS One , vol.9 , pp. e101179
    • Song, Y.1    Zhan, L.2    Yu, M.3    Huang, C.4    Meng, X.5    Ma, T.6    Zhang, L.7    Li, J.8
  • 316
    • 70149085707 scopus 로고    scopus 로고
    • Fibroblasts-a diverse population at the center of it all
    • Sorrell J.M., Caplan A.I. Fibroblasts-a diverse population at the center of it all. Int. Rev. Cell Mol. Biol. 2009, 276:161-214.
    • (2009) Int. Rev. Cell Mol. Biol. , vol.276 , pp. 161-214
    • Sorrell, J.M.1    Caplan, A.I.2
  • 317
    • 84887087639 scopus 로고    scopus 로고
    • Differential topical susceptibility to TGFbeta in intact and injured regions of the epithelium: key role in myofibroblast transition
    • Speight P., Nakano H., Kelley T.J., Hinz B., Kapus A. Differential topical susceptibility to TGFbeta in intact and injured regions of the epithelium: key role in myofibroblast transition. Mol. Biol. Cell 2013, 24:3326-3336.
    • (2013) Mol. Biol. Cell , vol.24 , pp. 3326-3336
    • Speight, P.1    Nakano, H.2    Kelley, T.J.3    Hinz, B.4    Kapus, A.5
  • 318
    • 84884577440 scopus 로고    scopus 로고
    • Wounded embryonic corneas exhibit nonfibrotic regeneration and complete innervation
    • Spurlin J.W., Lwigale P.Y. Wounded embryonic corneas exhibit nonfibrotic regeneration and complete innervation. Investig. Ophthalmol. Vis. Sci. 2013, 54:6334-6344.
    • (2013) Investig. Ophthalmol. Vis. Sci. , vol.54 , pp. 6334-6344
    • Spurlin, J.W.1    Lwigale, P.Y.2
  • 319
    • 33646870587 scopus 로고    scopus 로고
    • Corneal integrins and their functions
    • Stepp M.A. Corneal integrins and their functions. Exp. Eye Res. 2006, 83:3-15.
    • (2006) Exp. Eye Res. , vol.83 , pp. 3-15
    • Stepp, M.A.1
  • 322
    • 84857788858 scopus 로고    scopus 로고
    • Thrombospondin1 in tissue repair and fibrosis: TGF-beta-dependent and independent mechanisms
    • Sweetwyne M.T., Murphy-Ullrich J.E. Thrombospondin1 in tissue repair and fibrosis: TGF-beta-dependent and independent mechanisms. Matrix Biol. 2012, 31:178-186.
    • (2012) Matrix Biol. , vol.31 , pp. 178-186
    • Sweetwyne, M.T.1    Murphy-Ullrich, J.E.2
  • 324
    • 84930925721 scopus 로고    scopus 로고
    • Expression of α-smooth muscle actin determines the fate of mesenchymal stromal cells
    • Talele N., Fradette J., Davies J.E., Kapus A., Hinz B. Expression of α-smooth muscle actin determines the fate of mesenchymal stromal cells. Stem Cell Rep. 2015, 4:1016-1030.
    • (2015) Stem Cell Rep. , vol.4 , pp. 1016-1030
    • Talele, N.1    Fradette, J.2    Davies, J.E.3    Kapus, A.4    Hinz, B.5
  • 325
    • 84919665592 scopus 로고    scopus 로고
    • MicroRNA-29 mediates TGFbeta1-induced extracellular matrix synthesis by targeting Wnt/beta-catenin pathway in human orbital fibroblasts
    • Tan J., Tong B.D., Wu Y.J., Xiong W. MicroRNA-29 mediates TGFbeta1-induced extracellular matrix synthesis by targeting Wnt/beta-catenin pathway in human orbital fibroblasts. Int. J. Clin. Exp. Pathol. 2014, 7:7571-7577.
    • (2014) Int. J. Clin. Exp. Pathol. , vol.7 , pp. 7571-7577
    • Tan, J.1    Tong, B.D.2    Wu, Y.J.3    Xiong, W.4
  • 327
    • 77958018183 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in corneal function, biology and pathology
    • Tandon A., Tovey J.C., Sharma A., Gupta R., Mohan R.R. Role of transforming growth factor beta in corneal function, biology and pathology. Curr. Mol. Med. 2010, 10:565-578.
    • (2010) Curr. Mol. Med. , vol.10 , pp. 565-578
    • Tandon, A.1    Tovey, J.C.2    Sharma, A.3    Gupta, R.4    Mohan, R.R.5
  • 328
  • 330
    • 0030734064 scopus 로고    scopus 로고
    • Effect of topical anti-transforming growth factor-beta on corneal stromal haze after photorefractive keratectomy in rabbits
    • Thom S.B., Myers J.S., Rapuano C.J., Eagle R.C., Siepser S.B., Gomes J.A. Effect of topical anti-transforming growth factor-beta on corneal stromal haze after photorefractive keratectomy in rabbits. J. Cataract. Refract Surg. 1997, 23:1324-1330.
    • (1997) J. Cataract. Refract Surg. , vol.23 , pp. 1324-1330
    • Thom, S.B.1    Myers, J.S.2    Rapuano, C.J.3    Eagle, R.C.4    Siepser, S.B.5    Gomes, J.A.6
  • 332
    • 84860004951 scopus 로고    scopus 로고
    • Substratum stiffness and latrunculin B regulate matrix gene and protein expression in human trabecular meshwork cells
    • Thomasy S.M., Wood J.A., Kass P.H., Murphy C.J., Russell P. Substratum stiffness and latrunculin B regulate matrix gene and protein expression in human trabecular meshwork cells. Investig. Ophthalmol. Vis. Sci. 2012, 53:952-958.
    • (2012) Investig. Ophthalmol. Vis. Sci. , vol.53 , pp. 952-958
    • Thomasy, S.M.1    Wood, J.A.2    Kass, P.H.3    Murphy, C.J.4    Russell, P.5
  • 334
    • 84918773694 scopus 로고    scopus 로고
    • Cellular and extracellular matrix modulation of corneal stromal opacity
    • Torricelli A.A., Wilson S.E. Cellular and extracellular matrix modulation of corneal stromal opacity. Exp. Eye Res. 2014, 129:151-160.
    • (2014) Exp. Eye Res. , vol.129 , pp. 151-160
    • Torricelli, A.A.1    Wilson, S.E.2
  • 335
    • 84896973126 scopus 로고    scopus 로고
    • TGF-beta activation and function in immunity
    • Travis M.A., Sheppard D. TGF-beta activation and function in immunity. Annu. Rev. Immunol. 2014, 32:51-82.
    • (2014) Annu. Rev. Immunol. , vol.32 , pp. 51-82
    • Travis, M.A.1    Sheppard, D.2
  • 338
    • 33748563578 scopus 로고    scopus 로고
    • Immunohistochemical localization of EGF, TGF-alpha, TGF-beta, and their receptors in rat corneas during healing of excimer laser ablation
    • Tuli S.S., Liu R., Chen C., Blalock T.D., Goldstein M., Schultz G.S. Immunohistochemical localization of EGF, TGF-alpha, TGF-beta, and their receptors in rat corneas during healing of excimer laser ablation. Curr. Eye Res. 2006, 31:709-719.
    • (2006) Curr. Eye Res. , vol.31 , pp. 709-719
    • Tuli, S.S.1    Liu, R.2    Chen, C.3    Blalock, T.D.4    Goldstein, M.5    Schultz, G.S.6
  • 339
    • 84874958737 scopus 로고    scopus 로고
    • Function and fate of myofibroblasts after myocardial infarction
    • Turner N.A., Porter K.E. Function and fate of myofibroblasts after myocardial infarction. Fibrogenes. Tissue Repair 2013, 6:5.
    • (2013) Fibrogenes. Tissue Repair , vol.6 , pp. 5
    • Turner, N.A.1    Porter, K.E.2
  • 340
    • 77954938543 scopus 로고    scopus 로고
    • Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells
    • Twarock S., Tammi M.I., Savani R.C., Fischer J.W. Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells. J. Biol. Chem. 2010, 285:23274-23282.
    • (2010) J. Biol. Chem. , vol.285 , pp. 23274-23282
    • Twarock, S.1    Tammi, M.I.2    Savani, R.C.3    Fischer, J.W.4
  • 342
    • 56249141146 scopus 로고    scopus 로고
    • Antitransforming growth factor-beta therapy in fibrosis: recent progress and implications for systemic sclerosis
    • Varga J., Pasche B. Antitransforming growth factor-beta therapy in fibrosis: recent progress and implications for systemic sclerosis. Curr. Opin. Rheumatol. 2008, 20:720-728.
    • (2008) Curr. Opin. Rheumatol. , vol.20 , pp. 720-728
    • Varga, J.1    Pasche, B.2
  • 344
    • 70449517272 scopus 로고    scopus 로고
    • Periostin differentially induces proliferation, contraction and apoptosis of primary Dupuytren's disease and adjacent palmar fascia cells
    • Vi L., Feng L., Zhu R.D., Wu Y., Satish L., Gan B.S., O'Gorman D.B. Periostin differentially induces proliferation, contraction and apoptosis of primary Dupuytren's disease and adjacent palmar fascia cells. Exp. Cell Res. 2009, 315:3574-3586.
    • (2009) Exp. Cell Res. , vol.315 , pp. 3574-3586
    • Vi, L.1    Feng, L.2    Zhu, R.D.3    Wu, Y.4    Satish, L.5    Gan, B.S.6    O'Gorman, D.B.7
  • 346
    • 0026702586 scopus 로고
    • Proliferative retinal diseases: myofibroblasts cause chronic vitreoretinal traction
    • Walshe R., Esser P., Wiedemann P., Heimann K. Proliferative retinal diseases: myofibroblasts cause chronic vitreoretinal traction. Br. J. Ophthalmol. 1992, 76:550-552.
    • (1992) Br. J. Ophthalmol. , vol.76 , pp. 550-552
    • Walshe, R.1    Esser, P.2    Wiedemann, P.3    Heimann, K.4
  • 347
    • 6344281040 scopus 로고    scopus 로고
    • Proteomic profiling of bone marrow mesenchymal stem cells upon transforming growth factor beta1 stimulation
    • Wang D., Park J.S., Chu J.S., Krakowski A., Luo K., Chen D.J., Li S. Proteomic profiling of bone marrow mesenchymal stem cells upon transforming growth factor beta1 stimulation. J. Biol. Chem. 2004, 279:43725-43734.
    • (2004) J. Biol. Chem. , vol.279 , pp. 43725-43734
    • Wang, D.1    Park, J.S.2    Chu, J.S.3    Krakowski, A.4    Luo, K.5    Chen, D.J.6    Li, S.7
  • 348
    • 84863746756 scopus 로고    scopus 로고
    • Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus
    • Wang H., Haeger S.M., Kloxin A.M., Leinwand L.A., Anseth K.S. Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus. PLoS One 2012, 7:e39969.
    • (2012) PLoS One , vol.7 , pp. e39969
    • Wang, H.1    Haeger, S.M.2    Kloxin, A.M.3    Leinwand, L.A.4    Anseth, K.S.5
  • 350
    • 67649981446 scopus 로고    scopus 로고
    • Modulation of TGFbeta1-dependent myofibroblast differentiation by hyaluronan
    • Webber J., Jenkins R.H., Meran S., Phillips A., Steadman R. Modulation of TGFbeta1-dependent myofibroblast differentiation by hyaluronan. Am. J. Pathol. 2009, 175:148-160.
    • (2009) Am. J. Pathol. , vol.175 , pp. 148-160
    • Webber, J.1    Jenkins, R.H.2    Meran, S.3    Phillips, A.4    Steadman, R.5
  • 354
    • 0038676258 scopus 로고    scopus 로고
    • Regulation of wound healing by growth factors and cytokines
    • Werner S., Grose R. Regulation of wound healing by growth factors and cytokines. Physiol. Rev. 2003, 83:835-870.
    • (2003) Physiol. Rev. , vol.83 , pp. 835-870
    • Werner, S.1    Grose, R.2
  • 355
    • 33745341213 scopus 로고    scopus 로고
    • The keratocyte: corneal stromal cell with variable repair phenotypes
    • West-Mays J.A., Dwivedi D.J. The keratocyte: corneal stromal cell with variable repair phenotypes. Int. J. Biochem. Cell Biol. 2006, 38:1625-1631.
    • (2006) Int. J. Biochem. Cell Biol. , vol.38 , pp. 1625-1631
    • West-Mays, J.A.1    Dwivedi, D.J.2
  • 356
    • 84861689519 scopus 로고    scopus 로고
    • Corneal myofibroblast biology and pathobiology: generation, persistence, and transparency
    • Wilson S.E. Corneal myofibroblast biology and pathobiology: generation, persistence, and transparency. Exp. Eye Res. 2012, 99:78-88.
    • (2012) Exp. Eye Res. , vol.99 , pp. 78-88
    • Wilson, S.E.1
  • 357
    • 34547856274 scopus 로고    scopus 로고
    • Apoptosis in the initiation, modulation and termination of the corneal wound healing response
    • Wilson S.E., Chaurasia S.S., Medeiros F.W. Apoptosis in the initiation, modulation and termination of the corneal wound healing response. Exp. Eye Res. 2007, 85:305-311.
    • (2007) Exp. Eye Res. , vol.85 , pp. 305-311
    • Wilson, S.E.1    Chaurasia, S.S.2    Medeiros, F.W.3
  • 358
    • 0034928852 scopus 로고    scopus 로고
    • The corneal wound healing response: cytokine-mediated interaction of the epithelium, stroma, and inflammatory cells
    • Wilson S.E., Mohan R.R., Mohan R.R., Ambrosio R., Hong J., Lee J. The corneal wound healing response: cytokine-mediated interaction of the epithelium, stroma, and inflammatory cells. Prog. Retin Eye Res. 2001, 20:625-637.
    • (2001) Prog. Retin Eye Res. , vol.20 , pp. 625-637
    • Wilson, S.E.1    Mohan, R.R.2    Mohan, R.R.3    Ambrosio, R.4    Hong, J.5    Lee, J.6
  • 360
    • 58149269409 scopus 로고    scopus 로고
    • Bone marrow-derived human mesenchymal stem cells become quiescent on soft substrates but remain responsive to chemical or mechanical stimuli
    • Winer J.P., Janmey P.A., McCormick M.E., Funaki M. Bone marrow-derived human mesenchymal stem cells become quiescent on soft substrates but remain responsive to chemical or mechanical stimuli. Tissue Eng. Part A 2009, 15:147-154.
    • (2009) Tissue Eng. Part A , vol.15 , pp. 147-154
    • Winer, J.P.1    Janmey, P.A.2    McCormick, M.E.3    Funaki, M.4
  • 361
    • 49049110677 scopus 로고    scopus 로고
    • Integrins and the activation of latent transforming growth factor beta1-an intimate relationship
    • Wipff P.J., Hinz B. Integrins and the activation of latent transforming growth factor beta1-an intimate relationship. Eur. J. Cell Biol. 2008, 87:601-615.
    • (2008) Eur. J. Cell Biol. , vol.87 , pp. 601-615
    • Wipff, P.J.1    Hinz, B.2
  • 362
    • 37249044357 scopus 로고    scopus 로고
    • Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix
    • Wipff P.J., Rifkin D.B., Meister J.J., Hinz B. Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix. J. Cell Biol. 2007, 179:1311-1323.
    • (2007) J. Cell Biol. , vol.179 , pp. 1311-1323
    • Wipff, P.J.1    Rifkin, D.B.2    Meister, J.J.3    Hinz, B.4
  • 363
    • 84898792564 scopus 로고    scopus 로고
    • Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis
    • Wollin L., Maillet I., Quesniaux V., Holweg A., Ryffel B. Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis. J. Pharmacol. Exp. Ther. 2014, 349:209-220.
    • (2014) J. Pharmacol. Exp. Ther. , vol.349 , pp. 209-220
    • Wollin, L.1    Maillet, I.2    Quesniaux, V.3    Holweg, A.4    Ryffel, B.5
  • 365
    • 84876800337 scopus 로고    scopus 로고
    • Macrophage biology in development, homeostasis and disease
    • Wynn T.A., Chawla A., Pollard J.W. Macrophage biology in development, homeostasis and disease. Nature 2013, 496:445-455.
    • (2013) Nature , vol.496 , pp. 445-455
    • Wynn, T.A.1    Chawla, A.2    Pollard, J.W.3
  • 366
    • 84863702343 scopus 로고    scopus 로고
    • Mechanisms of fibrosis: therapeutic translation for fibrotic disease
    • Wynn T.A., Ramalingam T.R. Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat. Med. 2012, 18:1028-1040.
    • (2012) Nat. Med. , vol.18 , pp. 1028-1040
    • Wynn, T.A.1    Ramalingam, T.R.2
  • 368
    • 70349229692 scopus 로고    scopus 로고
    • Hypoxia reduces TGFbeta1-induced corneal keratocyte myofibroblast transformation
    • Xing D., Bonanno J.A. Hypoxia reduces TGFbeta1-induced corneal keratocyte myofibroblast transformation. Mol. Vis. 2009, 15:1827-1834.
    • (2009) Mol. Vis. , vol.15 , pp. 1827-1834
    • Xing, D.1    Bonanno, J.A.2
  • 369
    • 84961636517 scopus 로고    scopus 로고
    • Markers for distinguishing cultured human corneal endothelial cells from corneal stromal myofibroblasts
    • Yamaguchi M., Shima N., Kimoto M., Ebihara N., Murakami A., Yamagami S. Markers for distinguishing cultured human corneal endothelial cells from corneal stromal myofibroblasts. Curr. Eye Res. 2014, 1-7.
    • (2014) Curr. Eye Res. , pp. 1-7
    • Yamaguchi, M.1    Shima, N.2    Kimoto, M.3    Ebihara, N.4    Murakami, A.5    Yamagami, S.6
  • 370
    • 84864291003 scopus 로고    scopus 로고
    • A selective inhibitor of the rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma
    • Yamamoto M., Quantock A.J., Young R.D., Okumura N., Ueno M., Sakamoto Y., Kinoshita S., Koizumi N. A selective inhibitor of the rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma. Mol. Vis. 2012, 18:1727-1739.
    • (2012) Mol. Vis. , vol.18 , pp. 1727-1739
    • Yamamoto, M.1    Quantock, A.J.2    Young, R.D.3    Okumura, N.4    Ueno, M.5    Sakamoto, Y.6    Kinoshita, S.7    Koizumi, N.8
  • 371
    • 84884852239 scopus 로고    scopus 로고
    • TRPV1 potentiates TGFbeta-induction of corneal myofibroblast development through an oxidative stress-mediated p38-SMAD2 signaling loop
    • Yang Y., Wang Z., Yang H., Wang L., Gillespie S.R., Wolosin J.M., Bernstein A.M., Reinach P.S. TRPV1 potentiates TGFbeta-induction of corneal myofibroblast development through an oxidative stress-mediated p38-SMAD2 signaling loop. PLoS One 2013, 8:e77300.
    • (2013) PLoS One , vol.8 , pp. e77300
    • Yang, Y.1    Wang, Z.2    Yang, H.3    Wang, L.4    Gillespie, S.R.5    Wolosin, J.M.6    Bernstein, A.M.7    Reinach, P.S.8
  • 373
    • 0032923511 scopus 로고    scopus 로고
    • Interferon-gamma inhibits the myofibroblastic phenotype of rat palatal fibroblasts induced by transforming growth factor-beta1 in vitro
    • Yokozeki M., Baba Y., Shimokawa H., Moriyama K., Kuroda T. Interferon-gamma inhibits the myofibroblastic phenotype of rat palatal fibroblasts induced by transforming growth factor-beta1 in vitro. FEBS Lett. 1999, 442:61-64.
    • (1999) FEBS Lett. , vol.442 , pp. 61-64
    • Yokozeki, M.1    Baba, Y.2    Shimokawa, H.3    Moriyama, K.4    Kuroda, T.5
  • 375
    • 78650552589 scopus 로고    scopus 로고
    • Forcing form and function: biomechanical regulation of tumor evolution
    • Yu H., Mouw J.K., Weaver V.M. Forcing form and function: biomechanical regulation of tumor evolution. Trends Cell Biol. 2011, 21:47-56.
    • (2011) Trends Cell Biol. , vol.21 , pp. 47-56
    • Yu, H.1    Mouw, J.K.2    Weaver, V.M.3
  • 376
    • 77955602944 scopus 로고    scopus 로고
    • Resolved: EMT produces fibroblasts in the kidney
    • Zeisberg M., Duffield J.S. Resolved: EMT produces fibroblasts in the kidney. J. Am. Soc. Nephrol. 2010, 21:1247-1253.
    • (2010) J. Am. Soc. Nephrol. , vol.21 , pp. 1247-1253
    • Zeisberg, M.1    Duffield, J.S.2
  • 377
    • 80053279083 scopus 로고    scopus 로고
    • Platelet-derived growth factor involvement in myocardial remodeling following infarction
    • Zhao W., Zhao T., Huang V., Chen Y., Ahokas R.A., Sun Y. Platelet-derived growth factor involvement in myocardial remodeling following infarction. J. Mol. Cell Cardiol. 2011, 51:830-838.
    • (2011) J. Mol. Cell Cardiol. , vol.51 , pp. 830-838
    • Zhao, W.1    Zhao, T.2    Huang, V.3    Chen, Y.4    Ahokas, R.A.5    Sun, Y.6
  • 379
    • 84865408942 scopus 로고    scopus 로고
    • Specificity of latent TGF-beta binding protein (LTBP) incorporation into matrix: role of fibrillins and fibronectin
    • Zilberberg L., Todorovic V., Dabovic B., Horiguchi M., Courousse T., Sakai L.Y., Rifkin D.B. Specificity of latent TGF-beta binding protein (LTBP) incorporation into matrix: role of fibrillins and fibronectin. J. Cell Physiol. 2012, 227:3828-3836.
    • (2012) J. Cell Physiol. , vol.227 , pp. 3828-3836
    • Zilberberg, L.1    Todorovic, V.2    Dabovic, B.3    Horiguchi, M.4    Courousse, T.5    Sakai, L.Y.6    Rifkin, D.B.7


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