Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 304, Issue 6, 2013, Pages

  Perepelyuk, Maryna ^a   Terajima, Masahiko ^e   Wang, Andrew Y ^d   Georges, Penelope C ^c   Janmey, Paul A ^b,c   Yamauchi, Mitsuo ^e   Wells, Rebecca G ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^e North Carolina Oral Health Institute   (United States)

Author keywords

Collagen cross linking; Deoxypyridinoline; Extracellular matrix; Liver fibrosis; Pyridinoline

Indexed keywords

COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; DEOXYPYRIDINOLINE; ELASTIN; FIBRILLAR COLLAGEN; PROTEIN LYSINE 6 OXIDASE; PYRIDINOLINE; AMINO ACID;

ANIMAL CELL; ARTICLE; BILE DUCT LIGATION; BILIARY EXCRETION; CELL DIFFERENTIATION; CONTROLLED STUDY; CROSS LINKING; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FIBROBLAST; IN VITRO STUDY; KUPFFER CELL; LIVER FIBROSIS; LIVER INJURY; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; STELLATE CELL; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; FIBROSIS; LIVER; LIVER CELL; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME; TOXIC HEPATITIS; YOUNG MODULUS;

AMINO ACIDS; ANIMALS; COLLAGEN; DISEASE MODELS, ANIMAL; DRUG-INDUCED LIVER INJURY; ELASTIC MODULUS; EXTRACELLULAR MATRIX; FIBROBLASTS; FIBROSIS; HEPATIC STELLATE CELLS; HEPATOCYTES; KUPFFER CELLS; LIVER; PROTEIN-LYSINE 6-OXIDASE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

MLCS; MLOWN;

EID: 84878235678     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00222.2012     Document Type: Article

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