TRPV1 Potentiates TGFβ-Induction of Corneal Myofibroblast Development through an Oxidative Stress-Mediated p38-SMAD2 Signaling Loop

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Yang, Yuanquan ^a   Wang, Zheng ^b   Yang, Hua ^a   Wang, Lingyan ^b   Gillespie, Stephanie R ^b   Wolosin, J Mario ^b   Bernstein, Audrey M ^b   Reinach, Peter S ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CALCIUM ION; CAPSAZEPINE; FURA 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOPROTEIN; REACTIVE OXYGEN METABOLITE; SMAD2 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; VANILLOID RECEPTOR 1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; CORNEA; CORNEAL MYOFIBROBLAST; DNA TRANSFECTION; FLOW CYTOMETRY; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SPACE; MYOFIBROBLAST; NONHUMAN; ORGAN CULTURE; OXIDATIVE STRESS; PHENOTYPE; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STRESS FIBER; SWINE; WESTERN BLOTTING;

ACTINS; ALKALIES; ANIMALS; CALCIUM; CORNEA; CORNEAL OPACITY; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION; HUMANS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASE 9; MYOFIBROBLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SWINE; TISSUE CULTURE TECHNIQUES; TRANSFORMING GROWTH FACTOR BETA; TRPV CATION CHANNELS;

EID: 84884852239     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077300     Document Type: Article

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