Platelet-derived growth factor involvement in myocardial remodeling following infarction

Journal of Molecular and Cellular Cardiology

Volumn 51, Issue 5, 2011, Pages 830-838

  Zhao, Wenyuan ^a   Zhao, Tieqiang ^a   Huang, Valerie ^a   Chen, Yuanjian ^a   Ahokas, Robert A ^a   Sun, Yao ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Cardiac repair remodeling; Myocardial infarction; PDGF; PDGFR; Rat

Indexed keywords

MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PLATELET DERIVED GROWTH FACTOR C; PLATELET DERIVED GROWTH FACTOR D;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; FIBROGENESIS; GENE EXPRESSION; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LEYDIG CELL; MACROPHAGE; MALE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; TISSUE REPAIR;

ANIMALS; AUTORADIOGRAPHY; BLOTTING, WESTERN; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; ENDOMYOCARDIAL FIBROSIS; ENDOTHELIAL CELLS; GENE EXPRESSION; MACROPHAGES; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOFIBROBLASTS; ORGAN SPECIFICITY; PLATELET-DERIVED GROWTH FACTOR; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; VENTRICULAR REMODELING;

RATTUS;

EID: 80053279083     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.06.023     Document Type: Article

References (34)

1. Hoch R.V., Soriano P. Roles of PDGF in animal development. Development 2003, 130:4769-4784.
2. Li H., Fredriksson L., Li X., Eriksson U. PDGF-D is a potent transforming and angiogenic growth factor. Oncogene 2003, 22:1501-1510.
3. Wang Z., Kong D., Banerjee S., Li Y., Adsay N.V., Abbruzzese J., et al. Down-regulation of platelet-derived growth factor-D inhibits cell growth and angiogenesis through inactivation of Notch-1 and nuclear factor-kappaB signaling. Cancer Res 2007, 67:11377-11385.
4. Heldin C.H., Westermark B. Platelet-derived growth factors: a family of isoforms that bind to two distinct receptors. Br Med Bull 1989, 45:453-464.
5. Taylor C.C. Platelet-derived growth factor activates porcine thecal cell phosphatidylinositol-3-kinase-Akt/PKB and ras-extracellular signal-regulated kinase-1/2 kinase signaling pathways via the platelet-derived growth factor-beta receptor. Endocrinology 2000, 141:1545-1553.
6. Karvinen H., Rutanen J., Leppanen O., Lach R., Levonen A.L., Eriksson U., et al. PDGF-C and -D and their receptors PDGFR-alpha and PDGFR-beta in atherosclerotic human arteries. Eur J Clin Invest 2009, 39:320-327.
7. Perez J., Torres R.A., Rocic P., Cismowski M.J., Weber D.S., Darley-Usmar V.M., et al. PYK2 signaling is required for PDGF-dependent vascular smooth muscle cell proliferation. Am J Physiol Cell Physiol 2011, 301:C242-C251.
8. Trojanowska M. Role of PDGF in fibrotic diseases and systemic sclerosis. Rheumatology (Oxford) 2008, 47(Suppl. 5):v2-v4.
9. Ross R., Bowen-Pope D.F., Raines E.W. Platelet-derived growth factor and its role in health and disease. Philos Trans R Soc Lond B Biol Sci 1990, 327:155-169.
10. Bonner J.C. Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev 2004, 15:255-273.
11. Powell D.W., Mifflin R.C., Valentich J.D., Crowe S.E., Saada J.I., West A.B. Myofibroblasts. I. Paracrine cells important in health and disease. Am J Physiol 1999, 277:C1-C9.
12. Kinnman N., Francoz C., Barbu V., Wendum D., Rey C., Hultcrantz R., et al. The myofibroblastic conversion of peribiliary fibrogenic cells distinct from hepatic stellate cells is stimulated by platelet-derived growth factor during liver fibrogenesis. Lab Invest 2003, 83:163-173.
13. Tangkijvanich P., Santiskulvong C., Melton A.C., Rozengurt E., Yee H.F. p38 MAP kinase mediates platelet-derived growth factor-stimulated migration of hepatic myofibroblasts. J Cell Physiol 2002, 191:351-361.
14. McGowan S.E., Grossmann R.E., Kimani P.W., Holmes A.J. Platelet-derived growth factor receptor-alpha-expressing cells localize to the alveolar entry ring and have characteristics of myofibroblasts during pulmonary alveolar septal formation. Anat Rec (Hoboken) 2008, 291:1649-1661.
15. Borkham-Kamphorst E., van Roeyen C.R., Ostendorf T., Floege J., Gressner A.M., Weiskirchen R. Pro-fibrogenic potential of PDGF-D in liver fibrosis. J Hepatol 2007, 46:1064-1074.
16. Czochra P., Klopcic B., Meyer E., Herkel J., Garcia-Lazaro J.F., Thieringer F., et al. Liver fibrosis induced by hepatic overexpression of PDGF-B in transgenic mice. J Hepatol 2006, 45:419-428.
17. Floege J., Eitner F., Alpers C.E. A new look at platelet-derived growth factor in renal disease. J Am Soc Nephrol 2008, 19:12-23.
18. Shih A.H., Holland E.C. Platelet-derived growth factor (PDGF) and glial tumorigenesis. Cancer Lett 2006, 232:139-147.
19. Sun Y., Cleutjens J.P., Diaz-Arias A.A., Weber K.T. Cardiac angiotensin converting enzyme and myocardial fibrosis in the rat. Cardiovasc Res 1994, 28:1423-1432.
20. Weber K.T., Sun Y., Cleutjens J.P. Structural remodeling of the infarcted rat heart. EXS 1996, 76:489-499.
21. Zhao W., Zhao D., Yan R., Sun Y. Cardiac oxidative stress and remodeling following infarction: role of NADPH oxidase. Cardiovasc Pathol 2009, 18:156-166.
22. Martinez Rosas M. Cardiac remodeling and inflammation. Arch Cardiol Mex 2006, 76(Suppl. 4):S58-S66.
23. Nah D.Y., Rhee M.Y. The inflammatory response and cardiac repair after myocardial infarction. Korean Circ J 2009, 39:393-398.
24. Zhao T, Zhao W, Chen Y, Ahokas RA, Sun Y. Acidic and basic fibroblast growth factors involved in cardiac angiogenesis following infarction. Int J Cardiol in press.
25. Sun Y., Weber K.T. Angiotensin II receptor binding following myocardial infarction in the rat. Cardiovasc Res 1994, 28:1623-1628.
26. Zhao W., Zhao T., Chen Y., Ahokas R.A., Sun Y. Reactive oxygen species promote angiogenesis in the infarcted rat heart. Int J Exp Pathol 2009, 90:621-629.
27. Frangogiannis N.G., Smith C.W., Entman M.L. The inflammatory response in myocardial infarction. Cardiovasc Res 2002, 53:31-47.
28. Sun Y., Weber K.T. Infarct scar: a dynamic tissue. Cardiovasc Res 2000, 46:250-256.
29. Weber K.T., Sun Y., Tyagi S.C., Cleutjens J.P. Collagen network of the myocardium: function, structural remodeling and regulatory mechanisms. J Mol Cell Cardiol 1994, 26:279-292.
30. Kumagai S., Ohtani H., Nagai T., Funa K., Hiwatashi N.O., Shimosegawa, et al. Platelet-derived growth factor and its receptors are expressed in areas of both active inflammation and active fibrosis in inflammatory bowel disease. Tohoku J Exp Med 2001, 195:21-33.
31. Takeuchi H., Kanzawa T., Kondo Y., Kondo S. Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells. Br J Cancer 2004, 90:1069-1075.
32. Taneda S., Hudkins K.L., Topouzis S., Gilbertson D.G., Ophascharoensuk V., Truong L., et al. Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury. J Am Soc Nephrol 2003, 14:2544-2555.
33. McKaig B.C., Hughes K., Tighe P.J., Mahida Y.R. Differential expression of TGF-beta isoforms by normal and inflammatory bowel disease intestinal myofibroblasts. Am J Physiol Cell Physiol 2002, 282:C172-C182.
34. Shim A.H., Liu H., Focia P.J., Chen X., Lin P.C., He X. Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex. Proc Natl Acad Sci U S A 2010, 107:11307-11312.