Lineage tracing and genetic ablation of ADAM12 + perivascular cells identify a major source of profibrotic cells during acute tissue injury

Nature Medicine

Volumn 18, Issue 8, 2012, Pages 1262-1270

  Dulauroy, Sophie ^a,b   Di Carlo, Selene E ^a,b   Langa, Francina ^a   Eberl, Gérard ^a,b   Peduto, Lucie ^a,b  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM12 METALLOPROTEINASE; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; INTERSTITIAL COLLAGENASE; METALLOPROTEINASE; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN S 100; SMOOTH MUSCLE ACTIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; WNT1 PROTEIN;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; BLOOD VESSEL WALL; CELL DIFFERENTIATION; CELL EXPANSION; CELL LINEAGE; CELL POPULATION; CELL PROLIFERATION; CELLS; CONTROLLED STUDY; DERMIS; DOWN REGULATION; FIBROSIS; GENE MAPPING; GENETICS; HEALING; IN VITRO STUDY; IN VIVO STUDY; LIVER INJURY; MESENCHYME CELL; MOUSE; MUSCLE; MUSCLE REGENERATION; MYOFIBROBLAST; NEUROMUSCULAR SYNAPSE; NONHUMAN; PERIVASCULAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SCAR FORMATION; SCHWANN CELL; STEM CELL; TISSUE INJURY;

ACUTE DISEASE; ADAM PROTEINS; ADIPOCYTES; ANIMALS; BLOOD VESSELS; CELL LINEAGE; CICATRIX; COBRA CARDIOTOXIN PROTEINS; COLLAGEN; CROSSES, GENETIC; DERMIS; EAR, EXTERNAL; FIBROSIS; FREUND'S ADJUVANT; GENE KNOCKDOWN TECHNIQUES; GENES, REPORTER; LEG INJURIES; MICE; MICE, TRANSGENIC; MUSCLE, SKELETAL; MYOFIBROBLASTS; PARABIOSIS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; SPECIFIC PATHOGEN-FREE ORGANISMS; STROMAL CELLS; WOUND HEALING;

EID: 84864722077     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2848     Document Type: Article

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