The complex interplay between ERK1/2, TGFβ/Smad, and Jagged/Notch signaling pathways in the regulation of epithelial-mesenchymal transition in retinal pigment epithelium cells

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Chen, Xiaoyun ^a   Xiao, Wei ^a   Wang, Wencong ^a   Luo, Lixia ^a   Ye, Shaobi ^a   Liu, Yizhi ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 4; FIBRONECTIN; JAGGED1; MITOGEN ACTIVATED PROTEIN KINASE 1; NERVE CELL ADHESION MOLECULE; NOTCH RECEPTOR; P CADHERIN; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; 1,3 BUTADIENE DERIVATIVE; 1,3 DIOXOLANE DERIVATIVE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; BENZAMIDE DERIVATIVE; CALCIUM BINDING PROTEIN; ENZYME INHIBITOR; MAPK1 PROTEIN, HUMAN; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 3; MULTIPROTEIN COMPLEX; NITRILE; NOTCH3 PROTEIN, HUMAN; SERRATE PROTEINS; SIGNAL PEPTIDE; TRANSFORMING GROWTH FACTOR BETA2;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; HUMAN; HUMAN CELL; PHENOTYPE; PIGMENT EPITHELIUM; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; RETINA DETACHMENT; SIGNAL TRANSDUCTION; UPREGULATION; VITREORETINOPATHY; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL LINE; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; GENETICS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BENZAMIDES; BLOTTING, WESTERN; BUTADIENES; CALCIUM-BINDING PROTEINS; CELL LINE; DIOXOLES; ENZYME INHIBITORS; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MULTIPROTEIN COMPLEXES; NITRILES; RECEPTORS, NOTCH; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMAD PROTEINS; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA2;

EID: 84900407266     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096365     Document Type: Article

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