메뉴 건너뛰기




Volumn 124, Issue 6, 2014, Pages 2299-2306

Cellular and molecular mechanisms in kidney fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

FORKHEAD TRANSCRIPTION FACTOR; FORKHEAD TRANSCRIPTION FACTOR FOXD1; UNCLASSIFIED DRUG;

EID: 84902179695     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI72267     Document Type: Review
Times cited : (494)

References (102)
  • 1
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351(13):1296-1305.
    • (2004) N Engl J Med. , vol.351 , Issue.13 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3    McCulloch, C.E.4    Hsu, C.Y.5
  • 2
    • 58249114250 scopus 로고    scopus 로고
    • Prevalence of CKD in the United States: A sensitivity analysis using the National Health and Nutrition Examination Survey (NHANES) 1999-2004
    • Snyder JJ, Foley RN, Collins AJ. Prevalence of CKD in the United States: a sensitivity analysis using the National Health and Nutrition Examination Survey (NHANES) 1999-2004. Am J Kidney Dis. 2009;53(2):218-228.
    • (2009) Am J Kidney Dis. , vol.53 , Issue.2 , pp. 218-228
    • Snyder, J.J.1    Foley, R.N.2    Collins, A.J.3
  • 3
    • 0024327913 scopus 로고
    • Glomerular localization of type III collagen in human kidney disease
    • Yoshioka K, et al. Glomerular localization of type III collagen in human kidney disease. Kidney Int. 1989;35(5):1203-1211.
    • (1989) Kidney Int. , vol.35 , Issue.5 , pp. 1203-1211
    • Yoshioka, K.1
  • 4
    • 0021249263 scopus 로고
    • The composition of glomerulosclerosis. I. Studies in focal sclerosis, crescentic glomerulonephritis, and membranoproliferative glomerulonephritis
    • Morel-Maroger Striker L, Killen PD, Chi E, Striker GE. The composition of glomerulosclerosis. I. Studies in focal sclerosis, crescentic glomerulonephritis, and membranoproliferative glomerulonephritis. Lab Invest. 1984;51(2):181-192.
    • (1984) Lab Invest. , vol.51 , Issue.2 , pp. 181-192
    • Morel-Maroger Striker, L.1    Killen, P.D.2    Chi, E.3    Striker, G.E.4
  • 5
    • 0026055832 scopus 로고
    • Identification of lymph and blood capillaries by immunohistochemical staining for various basement membrane components
    • Nerlich AG, Schleicher E. Identification of lymph and blood capillaries by immunohistochemical staining for various basement membrane components. Histochemistry. 1991;96(5):449-453.
    • (1991) Histochemistry. , vol.96 , Issue.5 , pp. 449-453
    • Nerlich, A.G.1    Schleicher, E.2
  • 6
    • 0035131924 scopus 로고    scopus 로고
    • Up-regulation of extracellular matrix proteoglycans and collagen type I in human crescentic glomerulonephritis
    • Stokes MB, Hudkins KL, Zaharia V, Taneda S, Alpers CE. Up-regulation of extracellular matrix proteoglycans and collagen type I in human crescentic glomerulonephritis. Kidney Int. 2001;59(2):532-542.
    • (2001) Kidney Int. , vol.59 , Issue.2 , pp. 532-542
    • Stokes, M.B.1    Hudkins, K.L.2    Zaharia, V.3    Taneda, S.4    Alpers, C.E.5
  • 7
    • 0015264624 scopus 로고
    • Dupuytren's contracture: Fibroblast contraction? An ultrastructural study
    • Gabbiani G, Majno G. Dupuytren's contracture: fibroblast contraction? An ultrastructural study. Am J Pathol. 1972;66(1):131-146.
    • (1972) Am J Pathol. , vol.66 , Issue.1 , pp. 131-146
    • Gabbiani, G.1    Majno, G.2
  • 8
    • 84864722077 scopus 로고    scopus 로고
    • Lineage tracing and genetic ablation of ADAM12 (+) perivascular cells identify a major source of profibrotic cells during acute tissue injury
    • Dulauroy S, Di Carlo SE, Langa F, Eberl G, Peduto L. Lineage tracing and genetic ablation of ADAM12 (+) perivascular cells identify a major source of profibrotic cells during acute tissue injury. Nat Med. 2012;18(8):1262-1270.
    • (2012) Nat Med. , vol.18 , Issue.8 , pp. 1262-1270
    • Dulauroy, S.1    Di Carlo, S.E.2    Langa, F.3    Eberl, G.4    Peduto, L.5
  • 9
    • 84872867267 scopus 로고    scopus 로고
    • LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1
    • Ren S, et al. LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1. Proc Natl Acad Sci U S A. 2013;110(4):1440-1445.
    • (2013) Proc Natl Acad Sci U S A. , vol.110 , Issue.4 , pp. 1440-1445
    • Ren, S.1
  • 10
    • 81155131228 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis
    • Chen YT, et al. Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis. Kidney Int. 2011;80(11):1170-1181.
    • (2011) Kidney Int. , vol.80 , Issue.11 , pp. 1170-1181
    • Chen, Y.T.1
  • 11
    • 79951816985 scopus 로고    scopus 로고
    • Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis
    • Lin SL, et al. Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis. Am J Pathol. 2011;178(2):911-923.
    • (2011) Am J Pathol. , vol.178 , Issue.2 , pp. 911-923
    • Lin, S.L.1
  • 12
    • 0015452408 scopus 로고
    • Smooth muscle antigens in platelets: Immunofluorescent detection using human anti-smooth muscle serum
    • Gabbiani G, Ryan GB, Badonnel MC, Majno G. Smooth muscle antigens in platelets: immunofluorescent detection using human anti-smooth muscle serum. Pathol Biol (Paris). 1972;suppl:6-10.
    • (1972) Pathol Biol (Paris) , Issue.SUPPL. , pp. 6-10
    • Gabbiani, G.1    Ryan, G.B.2    Badonnel, M.C.3    Majno, G.4
  • 15
    • 73949096744 scopus 로고    scopus 로고
    • Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis
    • Humphreys BD, et al. Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol. 2010;176(1):85-97.
    • (2010) Am J Pathol. , vol.176 , Issue.1 , pp. 85-97
    • Humphreys, B.D.1
  • 16
    • 57149113728 scopus 로고    scopus 로고
    • Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney
    • Lin SL, Kisseleva T, Brenner DA, Duffield JS. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am J Pathol. 2008;173(6):1617-1627.
    • (2008) Am J Pathol. , vol.173 , Issue.6 , pp. 1617-1627
    • Lin, S.L.1    Kisseleva, T.2    Brenner, D.A.3    Duffield, J.S.4
  • 17
    • 43049125804 scopus 로고    scopus 로고
    • Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells
    • Ichimura T, Asseldonk EJ, Humphreys BD, Gunaratnam L, Duffield JS, Bonventre JV. Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells. J Clin Invest. 2008;118(5):1657-1668.
    • (2008) J Clin Invest. , vol.118 , Issue.5 , pp. 1657-1668
    • Ichimura, T.1    Asseldonk, E.J.2    Humphreys, B.D.3    Gunaratnam, L.4    Duffield, J.S.5    Bonventre, J.V.6
  • 18
    • 22144440464 scopus 로고    scopus 로고
    • Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells
    • Duffield JS, et al. Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest. 2005;115(7):1743-1755.
    • (2005) J Clin Invest. , vol.115 , Issue.7 , pp. 1743-1755
    • Duffield, J.S.1
  • 20
    • 27144493818 scopus 로고    scopus 로고
    • Versican is induced in infiltrating monocytes in myocardial infarction
    • Toeda K, et al. Versican is induced in infiltrating monocytes in myocardial infarction. Mol Cell Biochem. 2005;280(1-2):47-56.
    • (2005) Mol Cell Biochem. , vol.280 , Issue.1-2 , pp. 47-56
    • Toeda, K.1
  • 21
    • 77952394844 scopus 로고    scopus 로고
    • Bone marrow Ly6Chigh monocytes are selectively recruited to injured kidney and differentiate into functionally distinct populations
    • Lin SL, Castano AP, Nowlin BT, Lupher ML, Lupher ML Jr, Duffield JS. Bone marrow Ly6Chigh monocytes are selectively recruited to injured kidney and differentiate into functionally distinct populations. J Immunol. 2009;183(10):6733-6743.
    • (2009) J Immunol. , vol.183 , Issue.10 , pp. 6733-6743
    • Lin, S.L.1    Castano, A.P.2    Nowlin, B.T.3    Lupher, M.L.4    Lupher Jr., M.L.5    Duffield, J.S.6
  • 22
    • 80053394522 scopus 로고    scopus 로고
    • Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice
    • Asada N, et al. Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice. J Clin Invest. 2011;121(10):3981-3990.
    • (2011) J Clin Invest. , vol.121 , Issue.10 , pp. 3981-3990
    • Asada, N.1
  • 23
    • 79551521517 scopus 로고    scopus 로고
    • Epithelialmesenchymal transition (EMT) in kidney fibrosis: Fact or fantasy?
    • Kriz W, Kaissling B, Le Hir M. Epithelialmesenchymal transition (EMT) in kidney fibrosis: fact or fantasy? J Clin Invest. 2011;121(2):468-474.
    • (2011) J Clin Invest. , vol.121 , Issue.2 , pp. 468-474
    • Kriz, W.1    Kaissling, B.2    Le Hir, M.3
  • 24
    • 77957252460 scopus 로고    scopus 로고
    • Tubular overexpression of transforming growth factor-β1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells
    • Koesters R, et al. Tubular overexpression of transforming growth factor-β1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am J Pathol. 2010;177(2):632-643.
    • (2010) Am J Pathol. , vol.177 , Issue.2 , pp. 632-643
    • Koesters, R.1
  • 25
    • 78049449123 scopus 로고    scopus 로고
    • Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans
    • Bielesz B, et al. Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans. J Clin Invest. 2010;120(11):4040-4054.
    • (2010) J Clin Invest. , vol.120 , Issue.11 , pp. 4040-4054
    • Bielesz, B.1
  • 26
    • 77950565076 scopus 로고    scopus 로고
    • Autophagy is a component of epithelial cell fate in obstructive uropathy
    • Li L, Zepeda-Orozco D, Black R, Lin F. Autophagy is a component of epithelial cell fate in obstructive uropathy. Am J Pathol. 2010;176(4):1767- 1778.
    • (2010) Am J Pathol. , vol.176 , Issue.4 , pp. 1767-1778
    • Li, L.1    Zepeda-Orozco, D.2    Black, R.3    Lin, F.4
  • 27
    • 79959754392 scopus 로고    scopus 로고
    • Exploring the origin of the cells responsible for regeneration and fibrosis in the kidney
    • Endo T, et al. Exploring the origin of the cells responsible for regeneration and fibrosis in the kidney. J Am Soc Nephrol. 2010;21:F-FC163.
    • (2010) J Am Soc Nephrol. , vol.21
    • Endo, T.1
  • 28
    • 55749097944 scopus 로고    scopus 로고
    • Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney
    • Mugford JW, Sipila P, McMahon JA, McMahon AP. Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney. Dev Biol. 2008;324(1):88-98.
    • (2008) Dev Biol. , vol.324 , Issue.1 , pp. 88-98
    • Mugford, J.W.1    Sipila, P.2    McMahon, J.A.3    McMahon, A.P.4
  • 29
    • 39749172401 scopus 로고    scopus 로고
    • Intrinsic epithelial cells repair the kidney after injury
    • Humphreys BD, et al. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2008;2(3):284-291.
    • (2008) Cell Stem Cell , vol.2 , Issue.3 , pp. 284-291
    • Humphreys, B.D.1
  • 31
    • 79951678325 scopus 로고    scopus 로고
    • Origin of new cells in the adult kidney: Results from genetic labeling techniques
    • Duffield JS, Humphreys BD. Origin of new cells in the adult kidney: results from genetic labeling techniques. Kidney Int. 2011;79(5):494-501.
    • (2011) Kidney Int. , vol.79 , Issue.5 , pp. 494-501
    • Duffield, J.S.1    Humphreys, B.D.2
  • 32
    • 0014373275 scopus 로고
    • Ultrastructure of mammalian venous capillaries, venules, and small collecting veins
    • Rhodin JA. Ultrastructure of mammalian venous capillaries, venules, and small collecting veins. J Ultrastruct Res. 1968;25(5):452-500.
    • (1968) J Ultrastruct Res. , vol.25 , Issue.5 , pp. 452-500
    • Rhodin, J.A.1
  • 33
    • 0020965804 scopus 로고
    • Fibronectin in the microvasculature: Localization in the pericyte-endothelial interstitium
    • Courtoy PJ, Boyles J. Fibronectin in the microvasculature: localization in the pericyte-endothelial interstitium. J Ultrastruct Res. 1983;83(3):258-273.
    • (1983) J Ultrastruct Res. , vol.83 , Issue.3 , pp. 258-273
    • Courtoy, P.J.1    Boyles, J.2
  • 34
    • 25444463573 scopus 로고    scopus 로고
    • Endothelial/pericyte interactions
    • Armulik A, Abramsson A, Betsholtz C. Endothelial/pericyte interactions. Circ Res. 2005;97(6):512-523.
    • (2005) Circ Res. , vol.97 , Issue.6 , pp. 512-523
    • Armulik, A.1    Abramsson, A.2    Betsholtz, C.3
  • 35
    • 0035015517 scopus 로고    scopus 로고
    • Pericytes: Cell biology and pathology
    • Allt G, Lawrenson JG. Pericytes: cell biology and pathology. Cells Tissues Organs. 2001;169(1):1-11.
    • (2001) Cells Tissues Organs. , vol.169 , Issue.1 , pp. 1-11
    • Allt, G.1    Lawrenson, J.G.2
  • 37
    • 84857111725 scopus 로고    scopus 로고
    • The origin of interstitial myofibroblasts in chronic kidney disease
    • Grgic I, Duffield JS, Humphreys BD. The origin of interstitial myofibroblasts in chronic kidney disease. Pediatr Nephrol. 2012;27(2):183-193.
    • (2012) Pediatr Nephrol. , vol.27 , Issue.2 , pp. 183-193
    • Grgic, I.1    Duffield, J.S.2    Humphreys, B.D.3
  • 38
    • 84871300122 scopus 로고    scopus 로고
    • Transforming growth factor beta-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis
    • Wu CF, et al. Transforming growth factor beta-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis. Am J Pathol. 2013;182(1):118-131.
    • (2013) Am J Pathol. , vol.182 , Issue.1 , pp. 118-131
    • Wu, C.F.1
  • 39
    • 84871215242 scopus 로고    scopus 로고
    • Learning in motion: Pericytes instruct migrating innate leukocytes
    • Alon R, Nourshargh S. Learning in motion: pericytes instruct migrating innate leukocytes. Nat Immunol. 2013;14(1):14-15.
    • (2013) Nat Immunol. , vol.14 , Issue.1 , pp. 14-15
    • Alon, R.1    Nourshargh, S.2
  • 40
    • 84886304100 scopus 로고    scopus 로고
    • Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis
    • Hung C, et al. Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis. Am J Respir Crit Care Med. 2013;188(7):820-830.
    • (2013) Am J Respir Crit Care Med. , vol.188 , Issue.7 , pp. 820-830
    • Hung, C.1
  • 41
    • 84882289111 scopus 로고    scopus 로고
    • Origin and function of myofibroblasts in kidney fibrosis
    • Le Bleu VS, et al. Origin and function of myofibroblasts in kidney fibrosis. Nat Med. 2013;19(8):1047-1053.
    • (2013) Nat Med. , vol.19 , Issue.8 , pp. 1047-1053
    • Le Bleu, V.S.1
  • 42
    • 84860645452 scopus 로고    scopus 로고
    • Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury
    • Schrimpf C, et al. Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury. J Am Soc Nephrol. 2012;23(5):868-883.
    • (2012) J Am Soc Nephrol. , vol.23 , Issue.5 , pp. 868-883
    • Schrimpf, C.1
  • 43
    • 84875748988 scopus 로고    scopus 로고
    • EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury
    • Kida Y, Ieronimakis N, Schrimpf C, Reyes M, Duffield JS. EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury. J Am Soc Nephrol. 2013;24(4):559-572.
    • (2013) J Am Soc Nephrol. , vol.24 , Issue.4 , pp. 559-572
    • Kida, Y.1    Ieronimakis, N.2    Schrimpf, C.3    Reyes, M.4    Duffield, J.S.5
  • 44
    • 84902141624 scopus 로고    scopus 로고
    • Development of the kidney peritubular microvascular niche ex vivo
    • Ligresti G, et al. Development of the kidney peritubular microvascular niche ex vivo. J Am Soc Nephrol. 2013;24:142A.
    • (2013) J Am Soc Nephrol. , vol.24
    • Ligresti, G.1
  • 45
    • 84880998205 scopus 로고    scopus 로고
    • Mural propagation of descending vasa recta responses to mechanical stimulation
    • Zhang Z, Payne K, Cao C, Pallone TL. Mural propagation of descending vasa recta responses to mechanical stimulation. Am J Physiol Renal Physiol. 2013;305(3):F286-F294.
    • (2013) Am J Physiol Renal Physiol. , vol.305 , Issue.3
    • Zhang, Z.1    Payne, K.2    Cao, C.3    Pallone, T.L.4
  • 46
    • 84855511323 scopus 로고    scopus 로고
    • Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition
    • Rock JR, et al. Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition. Proc Natl Acad Sci U S A. 2011;108(52):E1475-E1483.
    • (2011) Proc Natl Acad Sci U S A. , vol.108 , Issue.52
    • Rock, J.R.1
  • 47
    • 60749123442 scopus 로고    scopus 로고
    • A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney
    • Yu J, Carroll TJ, Rajagopal J, Kobayashi A, Ren Q, McMahon AP. A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney. Development. 2009;136(1):161-171.
    • (2009) Development. , vol.136 , Issue.1 , pp. 161-171
    • Yu, J.1    Carroll, T.J.2    Rajagopal, J.3    Kobayashi, A.4    Ren, Q.5    McMahon, A.P.6
  • 49
    • 0036080547 scopus 로고    scopus 로고
    • Control of descending vasa recta pericyte membrane potential by angiotensin II
    • Pallone TL, Huang JM. Control of descending vasa recta pericyte membrane potential by angiotensin II. Am J Physiol Renal Physiol. 2002;282(6):F1064- F1074.
    • (2002) Am J Physiol Renal Physiol. , vol.282 , Issue.6
    • Pallone, T.L.1    Huang, J.M.2
  • 50
    • 0035002936 scopus 로고    scopus 로고
    • Pericyte regulation of renal medullary blood flow
    • Pallone TL, Silldorff EP. Pericyte regulation of renal medullary blood flow. Exp Nephrol. 2001;9(3):165-170.
    • (2001) Exp Nephrol. , vol.9 , Issue.3 , pp. 165-170
    • Pallone, T.L.1    Silldorff, E.P.2
  • 52
    • 39549114844 scopus 로고    scopus 로고
    • Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: Application to cerebral hypoxia
    • Cakir T, Alsan S, Saybasili H, Akin A, Ulgen KO. Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. Theor Biol Med Model. 2007;4:48.
    • (2007) Theor Biol Med Model. , vol.4 , pp. 48
    • Cakir, T.1    Alsan, S.2    Saybasili, H.3    Akin, A.4    Ulgen, K.O.5
  • 53
    • 84861394103 scopus 로고    scopus 로고
    • The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors
    • Acharya A, et al. The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors. Development. 2012;139(12):2139-2149.
    • (2012) Development. , vol.139 , Issue.12 , pp. 2139-2149
    • Acharya, A.1
  • 54
    • 0029091682 scopus 로고
    • Identification and characterization of a fibroblast marker: FSP1
    • Strutz F, et al. Identification and characterization of a fibroblast marker: FSP1. J Cell Biol. 1995;130(2):393-405.
    • (1995) J Cell Biol. , vol.130 , Issue.2 , pp. 393-405
    • Strutz, F.1
  • 55
    • 55249103431 scopus 로고    scopus 로고
    • Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition
    • Zeisberg EM, Potenta SE, Sugimoto H, Zeisberg M, Kalluri R. Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition. J Am Soc Nephrol. 2008;19(12):2282-2287.
    • (2008) J Am Soc Nephrol. , vol.19 , Issue.12 , pp. 2282-2287
    • Zeisberg, E.M.1    Potenta, S.E.2    Sugimoto, H.3    Zeisberg, M.4    Kalluri, R.5
  • 56
    • 84860791933 scopus 로고    scopus 로고
    • Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling
    • Chang L, et al. Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling. Proc Natl Acad Sci U S A. 2012;109(18):6993-6998.
    • (2012) Proc Natl Acad Sci U S A. , vol.109 , Issue.18 , pp. 6993-6998
    • Chang, L.1
  • 57
    • 84879628976 scopus 로고    scopus 로고
    • The contentious ontogeny of fibrosis in the kidney
    • Nelson PJ. The contentious ontogeny of fibrosis in the kidney. Kidney Int. 2013;84(1):14-15.
    • (2013) Kidney Int. , vol.84 , Issue.1 , pp. 14-15
    • Nelson, P.J.1
  • 58
    • 84879693711 scopus 로고    scopus 로고
    • Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model
    • Reich B, et al. Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model. Kidney Int. 2013;84(1):78-89.
    • (2013) Kidney Int. , vol.84 , Issue.1 , pp. 78-89
    • Reich, B.1
  • 59
    • 84902154101 scopus 로고    scopus 로고
    • Myeloid lineage leukocytes retain lineage boundaries in models of kidney disease
    • Gomez I, Nakagawa N, Roach A, Duffield JS. Myeloid lineage leukocytes retain lineage boundaries in models of kidney disease. J Am Soc Nephrol. 2013;24:184A.
    • (2013) J Am Soc Nephrol. , vol.24
    • Gomez, I.1    Nakagawa, N.2    Roach, A.3    Duffield, J.S.4
  • 60
    • 0032403946 scopus 로고    scopus 로고
    • Repression of the mouse M-lysozyme gene involves both hindrance of enhancer factor binding to the methylated enhancer and histone deacetylation
    • Ammerpohl O, Schmitz A, Steinm ller L, Renkawitz R. Repression of the mouse M-lysozyme gene involves both hindrance of enhancer factor binding to the methylated enhancer and histone deacetylation. Nucleic Acids Res. 1998;26(23):5256-5260.
    • (1998) Nucleic Acids Res. , vol.26 , Issue.23 , pp. 5256-5260
    • Ammerpohl, O.1    Schmitz, A.2    Ller, L.S.3    Renkawitz, R.4
  • 61
    • 0033177995 scopus 로고    scopus 로고
    • Conditional gene targeting in macrophages and granulocytes using LysMcre mice
    • Clausen BE, Burkhardt C, Reith W, Renkawitz R, Forster I. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 1999;8(4):265-277.
    • (1999) Transgenic Res. , vol.8 , Issue.4 , pp. 265-277
    • Clausen, B.E.1    Burkhardt, C.2    Reith, W.3    Renkawitz, R.4    Forster, I.5
  • 62
    • 84902161382 scopus 로고    scopus 로고
    • MicroRNAs are critical regulators of FOXD1 progenitors and kidney stroma during nephrogenesis
    • Nakagawa N, Roach A, Gomez IG, Kobayashi A, Duffield JS. MicroRNAs are critical regulators of FOXD1 progenitors and kidney stroma during nephrogenesis. J Am Soc Nephrol. 2013;25:184A.
    • (2013) J Am Soc Nephrol. , vol.25
    • Nakagawa, N.1    Roach, A.2    Gomez, I.G.3    Kobayashi, A.4    Duffield, J.S.5
  • 63
    • 84860633548 scopus 로고    scopus 로고
    • Sonic hedgehog signaling mediates epithelial-mesenchymal communication and promotes renal fibrosis
    • Ding H, et al. Sonic hedgehog signaling mediates epithelial-mesenchymal communication and promotes renal fibrosis. J Am Soc Nephrol. 2012;23(5):801-813.
    • (2012) J Am Soc Nephrol. , vol.23 , Issue.5 , pp. 801-813
    • Ding, H.1
  • 64
    • 77952174830 scopus 로고    scopus 로고
    • Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
    • Yang L, Besschetnova TY, Brooks CR, Shah JV, Bonventre JV. Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat Med. 2010;16(5):535-543.
    • (2010) Nat Med. , vol.16 , Issue.5 , pp. 535-543
    • Yang, L.1    Besschetnova, T.Y.2    Brooks, C.R.3    Shah, J.V.4    Bonventre, J.V.5
  • 65
    • 84879749496 scopus 로고    scopus 로고
    • TLR-2/TLR-4 TREM-1 signaling pathway is dispensable in inflammatory myeloid cells during sterile kidney injury
    • Campanholle G, et al. TLR-2/TLR-4 TREM-1 signaling pathway is dispensable in inflammatory myeloid cells during sterile kidney injury. PLoS One. 2013;8(7):e68640.
    • (2013) PLoS One. , vol.8 , Issue.7
    • Campanholle, G.1
  • 66
    • 84864306054 scopus 로고    scopus 로고
    • Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo
    • Proebstl D, et al. Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. J Exp Med. 2012;209(6):1219- 1234.
    • (2012) J Exp Med. , vol.209 , Issue.6 , pp. 1219-1234
    • Proebstl, D.1
  • 68
    • 84902140588 scopus 로고    scopus 로고
    • Anti-miR21 protects collagen 4A3 deficient mice from progression of alport disease by decreasing oxidative stress
    • Gomez IG, et al. Anti-miR21 protects collagen 4A3 deficient mice from progression of alport disease by decreasing oxidative stress. J Am Soc Nephrol. 2013;24:93A.
    • (2013) J Am Soc Nephrol. , vol.24
    • Gomez, I.G.1
  • 69
    • 84862195154 scopus 로고    scopus 로고
    • Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
    • Kisseleva T, et al. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci U S A. 2012;109(24):9448-9453.
    • (2012) Proc Natl Acad Sci U S A. , vol.109 , Issue.24 , pp. 9448-9453
    • Kisseleva, T.1
  • 70
    • 77952116121 scopus 로고    scopus 로고
    • Methylation determines fibroblast activation and fibrogenesis in the kidney
    • Bechtel W, et al. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat Med. 2010;16(5):544-550.
    • (2010) Nat Med. , vol.16 , Issue.5 , pp. 544-550
    • Bechtel, W.1
  • 72
    • 0035722242 scopus 로고    scopus 로고
    • Glomerular endothelial cells and podocytes jointly synthesize laminin-1 and -11 chains
    • St John PL, Abrahamson DR. Glomerular endothelial cells and podocytes jointly synthesize laminin-1 and -11 chains. Kidney Int. 2001;60(3):1037-1046.
    • (2001) Kidney Int. , vol.60 , Issue.3 , pp. 1037-1046
    • St John, P.L.1    Abrahamson, D.R.2
  • 74
    • 84859846411 scopus 로고    scopus 로고
    • Subtotal ablation of parietal epithelial cells induces crescent formation
    • Sicking EM, et al. Subtotal ablation of parietal epithelial cells induces crescent formation. J Am Soc Nephrol. 2012;23(4):629-640.
    • (2012) J Am Soc Nephrol. , vol.23 , Issue.4 , pp. 629-640
    • Sicking, E.M.1
  • 75
    • 79960109593 scopus 로고    scopus 로고
    • Parietal epithelial cells participate in the formation of sclerotic lesions in focal segmental glomerulosclerosis
    • Smeets B, et al. Parietal epithelial cells participate in the formation of sclerotic lesions in focal segmental glomerulosclerosis. J Am Soc Nephrol. 2011;22(7):1262-1274.
    • (2011) J Am Soc Nephrol. , vol.22 , Issue.7 , pp. 1262-1274
    • Smeets, B.1
  • 76
  • 77
  • 79
    • 84884381509 scopus 로고    scopus 로고
    • M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway
    • Madsen DH, et al. M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway. J Cell Biol. 2013;202(6):951-966.
    • (2013) J Cell Biol. , vol.202 , Issue.6 , pp. 951-966
    • Madsen, D.H.1
  • 80
    • 72849117761 scopus 로고    scopus 로고
    • Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages
    • Atabai K, et al. Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages. J Clin Invest. 2009;119(12):3713-3722.
    • (2009) J Clin Invest. , vol.119 , Issue.12 , pp. 3713-3722
    • Atabai, K.1
  • 81
    • 79551654684 scopus 로고    scopus 로고
    • Distinct macrophage phenotypes contribute to kidney injury and repair
    • Lee S, et al. Distinct macrophage phenotypes contribute to kidney injury and repair. J Am Soc Nephrol. 2011;22(2):317-326.
    • (2011) J Am Soc Nephrol. , vol.22 , Issue.2 , pp. 317-326
    • Lee, S.1
  • 82
    • 77749246063 scopus 로고    scopus 로고
    • Macrophage Wnt7b is critical for kidney repair and regeneration
    • Lin SL, et al. Macrophage Wnt7b is critical for kidney repair and regeneration. Proc Natl Acad Sci U S A. 2010;107(9):4194-4199.
    • (2010) Proc Natl Acad Sci U S A. , vol.107 , Issue.9 , pp. 4194-4199
    • Lin, S.L.1
  • 83
    • 0037693895 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry
    • Visse R, Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res. 2003;92(8):827-839.
    • (2003) Circ Res. , vol.92 , Issue.8 , pp. 827-839
    • Visse, R.1    Nagase, H.2
  • 84
    • 0035794294 scopus 로고    scopus 로고
    • Matrix metalloproteinase 9 protects mice from anti-glomerular basement membrane nephritis through its fibrinolytic activity
    • Lelongt B, Bengatta S, Delauche M, Lund LR, Werb Z, Ronco PM. Matrix metalloproteinase 9 protects mice from anti-glomerular basement membrane nephritis through its fibrinolytic activity. J Exp Med. 2001;193(7):793-802.
    • (2001) J Exp Med. , vol.193 , Issue.7 , pp. 793-802
    • Lelongt, B.1    Bengatta, S.2    Delauche, M.3    Lund, L.R.4    Werb, Z.5    Ronco, P.M.6
  • 85
    • 0033932709 scopus 로고    scopus 로고
    • Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction
    • Ducharme A, et al. Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest. 2000;106(1):55-62.
    • (2000) J Clin Invest. , vol.106 , Issue.1 , pp. 55-62
    • Ducharme, A.1
  • 86
    • 0035947766 scopus 로고    scopus 로고
    • Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration
    • Kajita M, et al. Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration. J Cell Biol. 2001;153(5):893-904.
    • (2001) J Cell Biol. , vol.153 , Issue.5 , pp. 893-904
    • Kajita, M.1
  • 87
    • 84885998702 scopus 로고    scopus 로고
    • Matrix metalloproteinases and their inhibitors in turnover and degradation of extracellular matrix
    • Parks WC, Mecham RP, eds, Berlin, Germany: Springer-Verlag
    • Gill SE, Parks WC. Matrix metalloproteinases and their inhibitors in turnover and degradation of extracellular matrix. In: Parks WC, Mecham RP, eds. Extracellular Matrix Degradation. Berlin, Germany: Springer-Verlag; 2011:1-22.
    • (2011) Extracellular Matrix Degradation , pp. 1-22
    • Gill, S.E.1    Parks, W.C.2
  • 88
    • 0034912450 scopus 로고    scopus 로고
    • PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction
    • Oda T, et al. PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction. Kidney Int. 2001;60(2):587-596.
    • (2001) Kidney Int. , vol.60 , Issue.2 , pp. 587-596
    • Oda, T.1
  • 89
    • 0037192866 scopus 로고    scopus 로고
    • Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: Implications for reversibility of liver fibrosis
    • Murphy FR, et al. Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis. J Biol Chem. 2002;277(13):11069-11076.
    • (2002) J Biol Chem. , vol.277 , Issue.13 , pp. 11069-11076
    • Murphy, F.R.1
  • 90
    • 2142784516 scopus 로고    scopus 로고
    • MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover
    • Holmbeck K, et al. MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell. 1999;99(1):81-92.
    • (1999) Cell , vol.99 , Issue.1 , pp. 81-92
    • Holmbeck, K.1
  • 91
    • 33750495804 scopus 로고    scopus 로고
    • A critical role for the membrane-type 1 matrix metalloproteinase in collagen phagocytosis
    • Lee H, Overall CM, McCulloch CA, Sodek J. A critical role for the membrane-type 1 matrix metalloproteinase in collagen phagocytosis. Mol Biol Cell. 2006;17(11):4812-4826.
    • (2006) Mol Biol Cell , vol.17 , Issue.11 , pp. 4812-4826
    • Lee, H.1    Overall, C.M.2    McCulloch, C.A.3    Sodek, J.4
  • 92
    • 34247149014 scopus 로고    scopus 로고
    • Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis
    • Fallowfield JA, et al. Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis. J Immunol. 2007;178(8):5288-5295.
    • (2007) J Immunol. , vol.178 , Issue.8 , pp. 5288-5295
    • Fallowfield, J.A.1
  • 93
    • 13744255589 scopus 로고    scopus 로고
    • Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
    • Duffield JS, et al. Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J Clin Invest. 2005;115(1):56-65.
    • (2005) J Clin Invest. , vol.115 , Issue.1 , pp. 56-65
    • Duffield, J.S.1
  • 94
    • 84856815842 scopus 로고    scopus 로고
    • Mannose receptor 2 attenuates renal fibrosis
    • Lopez-Guisa JM, et al. Mannose receptor 2 attenuates renal fibrosis. J Am Soc Nephrol. 2012;23(2):236-251.
    • (2012) J Am Soc Nephrol. , vol.23 , Issue.2 , pp. 236-251
    • Lopez-Guisa, J.M.1
  • 95
    • 0034091793 scopus 로고    scopus 로고
    • Discoidin domain receptor 1 is activated independently of beta (1) integrin
    • Vogel W, Brakebusch C, Fassler R, Alves F, Ruggiero F, Pawson T. Discoidin domain receptor 1 is activated independently of beta (1) integrin. J Biol Chem. 2000;275(8):5779-5784.
    • (2000) J Biol Chem. , vol.275 , Issue.8 , pp. 5779-5784
    • Vogel, W.1    Brakebusch, C.2    Fassler, R.3    Alves, F.4    Ruggiero, F.5    Pawson, T.6
  • 97
    • 77956425361 scopus 로고    scopus 로고
    • Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
    • Barry-Hamilton V, et al. Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment. Nat Med. 2010;16(9):1009-1017.
    • (2010) Nat Med. , vol.16 , Issue.9 , pp. 1009-1017
    • Barry-Hamilton, V.1
  • 98
    • 0033638127 scopus 로고    scopus 로고
    • Molecular basis of renal fibrosis
    • Eddy AA. Molecular basis of renal fibrosis. Pediatr Nephrol. 2000;15(3-4):290-301.
    • (2000) Pediatr Nephrol. , vol.15 , Issue.3-4 , pp. 290-301
    • Eddy, A.A.1
  • 99
    • 33748741385 scopus 로고    scopus 로고
    • TIMP-3 inhibits the procollagen N-proteinase ADAMTS-2
    • Wang WM, Ge G, Lim NH, Nagase H, Greenspan DS. TIMP-3 inhibits the procollagen N-proteinase ADAMTS-2. Biochem J. 2006;398(3):515-519.
    • (2006) Biochem J. , vol.398 , Issue.3 , pp. 515-519
    • Wang, W.M.1    Ge, G.2    Lim, N.H.3    Nagase, H.4    Greenspan, D.S.5
  • 100
    • 84908005077 scopus 로고    scopus 로고
    • Translational profiles of medullary myofibroblasts during kidney fibrosis [published online ahead of print March 20, 2014]
    • doi: 10.1681/ASN.2013101143
    • Grgic I, et al. Translational profiles of medullary myofibroblasts during kidney fibrosis [published online ahead of print March 20, 2014]. J Am Soc Nephrol. doi: 10.1681/ASN.2013101143.
    • J Am Soc Nephrol.
    • Grgic, I.1
  • 101
    • 0035870995 scopus 로고    scopus 로고
    • Transgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterility
    • Li SW, et al. Transgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterility. Biochem J. 2001;355(pt 2):271-278.
    • (2001) Biochem J. , vol.355 , Issue.PART 2 , pp. 271-278
    • Li, S.W.1
  • 102
    • 84872867224 scopus 로고    scopus 로고
    • Pericyte progenitors at the crossroads between fibrosis and regeneration
    • Steinhauser ML, Lee RT. Pericyte progenitors at the crossroads between fibrosis and regeneration. Circ Res. 2013;112(2):230-232.
    • (2013) Circ Res. , vol.112 , Issue.2 , pp. 230-232
    • Steinhauser, M.L.1    Lee, R.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.