Selective targeting of TGF-β activation to treat Fibroinflammatory airway disease

Science Translational Medicine

Volumn 6, Issue 241, 2014, Pages

  Minagawa, Shunsuke ^a   Lou, Jianlong ^a   Seed, Robert I ^a   Cormier, Anthony ^a   Wu, Shenping ^a   Cheng, Yifan ^a   Murray, Lynne ^b,c   Tsui, Ping ^b   Connor, Jane ^b   Herbst, Ronald ^b   Govaerts, Cedric ^d   Barker, Tyren ^a   Cambier, Stephanie ^a   Yanagisawa, Haruhiko ^a   Goodsell, Amanda ^a   Hashimoto, Mitsuo ^a   Brand, Oliver J ^a   Cheng, Ran ^a   Ma, Royce ^a   McKnelly, Kate J ^a   Wen, Weihua ^a   Hill, Arthur ^a   Jablons, David ^a   Wolters, Paul ^a   Kitamura, Hideya ^a   Araya, Jun ^e   Barczak, Andrea J ^a   Erle, David J ^a   Reichardt, Louis F ^f   Marks, James D ^a   Baron, Jody L ^a   Nishimura, Stephen L ^a   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MEDIMMUNE   (United States)

^c MEDIMMUNE LTD   (United Kingdom)

^d FREE UNIVERSITY OF BRUSSELS   (Belgium)

^e JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ALPHAVBETA8 INTEGRIN; ANTIBODY; CIGARETTE SMOKE; RECOMBINANT ANTIBODY; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CELL SURFACE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BINDING; DRUG EFFICACY; DRUG TARGETING; ELECTRON MICROSCOPY; EPITOPE MAPPING; FEMALE; FIBROINFLAMMATORY AIRWAY DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDRODYNAMICS; IN VIVO STUDY; LIGAND BINDING; LUNG FIBROSIS; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFLAMMATION; TRANSCRIPTION INITIATION; ANIMAL; METABOLISM; TRACHEITIS; TRANSGENIC MOUSE;

ANIMALS; HUMANS; MICE; MICE, TRANSGENIC; TRACHEITIS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84903780541     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3008074     Document Type: Article

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