-
1
-
-
84655175061
-
Understanding fibrosis in systemic sclerosis: Shifting paradigms, emerging opportunities
-
Bhattacharyya S, Wei J, Varga J. Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities. Nat Rev Rheumatol. 2012;8:42-54.
-
(2012)
Nat Rev Rheumatol.
, vol.8
, pp. 42-54
-
-
Bhattacharyya, S.1
Wei, J.2
Varga, J.3
-
3
-
-
33847348491
-
Systemic sclerosis: A prototypic multisystem fibrotic disorder
-
DOI 10.1172/JCI31139
-
Varga J, Abraham D. Systemic sclerosis: a prototypic multisystem fibrotic disorder. J Clin Invest. 2007;117:557-67. (Pubitemid 46348510)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.3
, pp. 557-567
-
-
Varga, J.1
Abraham, D.2
-
4
-
-
0043074631
-
Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population
-
DOI 10.1002/art.11073
-
Mayes MD, Lacey Jr JV, Beebe-Dimmer J, et al. Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population. Arthritis Rheum. 2003;48:2246-55. (Pubitemid 36959206)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.8
, pp. 2246-2255
-
-
Mayes, M.D.1
Lacey Jr., J.V.2
Beebe-Dimmer, J.3
Gillespie, B.W.4
Cooper, B.5
Laing, T.J.6
Schottenfeld, D.7
-
5
-
-
0015359850
-
Connective tissue synthesis by scleroderma skin fibroblasts in cell culture
-
Leroy EC. Connective tissue synthesis by scleroderma skin fibroblasts in cell culture. J Exp Med. 1972;135:1351-62.
-
(1972)
J Exp Med.
, vol.135
, pp. 1351-1362
-
-
Leroy, E.C.1
-
6
-
-
84859073207
-
Recent developments in myofibroblast biology: Paradigms for connective tissue remodeling
-
Hinz B, Phan SH, Thannickal VJ, et al. Recent developments in myofibroblast biology: paradigms for connective tissue remodeling. Am J Pathol. 2012;180:1340-55.
-
(2012)
Am J Pathol.
, vol.180
, pp. 1340-1355
-
-
Hinz, B.1
Phan, S.H.2
Thannickal, V.J.3
-
7
-
-
0016283728
-
Platelets as a source of fibroblast growthpromoting activity
-
Kohler N, Lipton A. Platelets as a source of fibroblast growthpromoting activity. Exp Cell Res. 1974;87:297-301.
-
(1974)
Exp Cell Res.
, vol.87
, pp. 297-301
-
-
Kohler, N.1
Lipton, A.2
-
8
-
-
1842280753
-
A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro
-
Ross R, Glomset J, Kariya B, Harker L. A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Proc Natl Acad Sci USA. 1974;71:1207-10.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, pp. 1207-1210
-
-
Ross, R.1
Glomset, J.2
Kariya, B.3
Harker, L.4
-
9
-
-
44149090296
-
Role of platelet-derived growth factors in physiology and medicine
-
DOI 10.1101/gad.1653708
-
Andrae J, Gallini R, Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes Dev. 2008;22:1276-312. (Pubitemid 351717519)
-
(2008)
Genes and Development
, vol.22
, Issue.10
, pp. 1276-1312
-
-
Andrae, J.1
Gallini, R.2
Betsholtz, C.3
-
10
-
-
84862190770
-
B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin
-
Daoussis D, Tsamandas AC, Liossis SN, et al. B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin. Arthritis Res Ther. 2012;14:R145.
-
(2012)
Arthritis Res Ther.
, vol.14
-
-
Daoussis, D.1
Tsamandas, A.C.2
Liossis, S.N.3
-
11
-
-
0024539072
-
Immunohistologic demonstration of platelet-derived growth factor (PDGF) and sis-oncogene expression in scleroderma
-
Gay S, Jones Jr RE, Huang GQ, Gay RE. Immunohistologic demonstration of platelet-derived growth factor (PDGF) and sisoncogene expression in scleroderma. J Invest Dermatol. 1989;92:301-3. (Pubitemid 19061278)
-
(1989)
Journal of Investigative Dermatology
, vol.92
, Issue.2
, pp. 301-303
-
-
Gay, S.1
Jones Jr., R.E.2
Huang, G.-Q.3
Gay, R.E.4
-
12
-
-
0025014021
-
Increased expression of platelet-derived growth factor type B receptors in the skin of patients with systemic sclerosis
-
Klareskog L, Gustafsson R, Scheynius A, Hallgren R. Increased expression of platelet-derived growth factor type B receptors in the skin of patients with systemic sclerosis. Arthritis Rheum. 1990;33:1534-41. (Pubitemid 20362097)
-
(1990)
Arthritis and Rheumatism
, vol.33
, Issue.10
, pp. 1534-1541
-
-
Klareskog, L.1
Gustafsson, R.2
Scheynius, A.3
Hallgren, R.4
-
13
-
-
0032929924
-
Activation of microvascular pericytes in autoimmune Raynaud's phenomenon and systemic sclerosis
-
DOI 10.1002/1529-0131(199905)42:5<930::AID-ANR11>3.0.CO;2-1
-
Rajkumar VS, Sundberg C, Abraham DJ, et al. Activation of microvascular pericytes in autoimmune Raynaud's phenomenon and systemic sclerosis. Arthritis Rheum. 1999;42:930-41. (Pubitemid 29215003)
-
(1999)
Arthritis and Rheumatism
, vol.42
, Issue.5
, pp. 930-941
-
-
Rajkumar, V.S.1
Sundberg, C.2
Abraham, D.J.3
Rubin, K.4
Black, C.M.5
-
14
-
-
0024549655
-
Increased plasma levels of platelet-derived growth factor activity in patients with progressive systemic sclerosis
-
Pandolfi A, Florita M, Altomare G, et al. Increased plasma levels of platelet-derived growth factor activity in patients with progressive systemic sclerosis. Proc Soc Exp Biol Med. 1989;191:1-4. (Pubitemid 19126434)
-
(1989)
Proceedings of the Society for Experimental Biology and Medicine
, vol.191
, Issue.1
, pp. 1-4
-
-
Pandolfi, A.1
Florita, M.2
Altomare, G.3
Pigatto, P.4
Donati, M.B.5
Poggi, A.6
-
15
-
-
0028973641
-
Elevated levels of platelet derived growth factor and transforming growth factor-beta 1 in bronchoalveolar lavage fluid from patients with scleroderma
-
Ludwicka A, Ohba T, Trojanowska M, et al. Elevated levels of platelet derived growth factor and transforming growth factor-beta 1 in bronchoalveolar lavage fluid from patients with scleroderma. J Rheumatol. 1995;22:1876-83.
-
(1995)
J Rheumatol.
, vol.22
, pp. 1876-1883
-
-
Ludwicka, A.1
Ohba, T.2
Trojanowska, M.3
-
17
-
-
59649093844
-
Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis
-
Olson LE, Soriano P. Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis. Dev Cell. 2009;16:303-13.
-
(2009)
Dev Cell.
, vol.16
, pp. 303-313
-
-
Olson, L.E.1
Soriano, P.2
-
18
-
-
33846247466
-
Postnatal induction of transforming growth factor β signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma
-
DOI 10.1002/art.22328
-
Sonnylal S, Denton CP, Zheng B, et al. Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma. Arthritis Rheum. 2007;56:334-44. (Pubitemid 46106207)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.1
, pp. 334-344
-
-
Sonnylal, S.1
Denton, C.P.2
Zheng, B.3
Keene, D.R.4
He, R.5
Adams, H.P.6
VanPelt, C.S.7
Geng, Y.J.8
Deng, J.M.9
Behringer, R.R.10
De Crombrugghe, B.11
-
19
-
-
0032875460
-
Mechanism of action and in vivo role of platelet-derived growth factor
-
Heldin CH, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev. 1999;79:1283-316. (Pubitemid 29473317)
-
(1999)
Physiological Reviews
, vol.79
, Issue.4
, pp. 1283-1316
-
-
Heldin, C.-H.1
Westermark, B.2
-
20
-
-
2942682928
-
Regulation of PDGF and its receptors in fibrotic diseases
-
DOI 10.1016/j.cytogfr.2004.03.006, PII S1359610104000164
-
Bonner JC. Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev. 2004;15:255-73. (Pubitemid 38781050)
-
(2004)
Cytokine and Growth Factor Reviews
, vol.15
, Issue.4
, pp. 255-273
-
-
Bonner, J.C.1
-
21
-
-
33745277147
-
Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis
-
Baroni SS, Santillo M, Bevilacqua F, et al. Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis. N Engl J Med. 2006;354:2667-76.
-
(2006)
N Engl J Med.
, vol.354
, pp. 2667-2676
-
-
Baroni, S.S.1
Santillo, M.2
Bevilacqua, F.3
-
22
-
-
65249139405
-
Lack of evidence of stimulatory autoantibodies to platelet-derived growth factor receptor in patients with systemic sclerosis
-
Classen JF, Henrohn D, Rorsman F, et al. Lack of evidence of stimulatory autoantibodies to platelet-derived growth factor receptor in patients with systemic sclerosis. Arthritis Rheum. 2009;60:1137-44.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1137-1144
-
-
Classen, J.F.1
Henrohn, D.2
Rorsman, F.3
-
23
-
-
65249190778
-
Lack of detection of agonist activity by antibodies to platelet-derived growth factor receptor alpha in a subset of normal and systemic sclerosis patient sera
-
Loizos N, Lariccia L, Weiner J, et al. Lack of detection of agonist activity by antibodies to platelet-derived growth factor receptor alpha in a subset of normal and systemic sclerosis patient sera. Arthritis Rheum. 2009;60:1145-51.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1145-1151
-
-
Loizos, N.1
Lariccia, L.2
Weiner, J.3
-
24
-
-
0142243109
-
Roles of PDGF in animal development
-
DOI 10.1242/dev.00721
-
Hoch RV, Soriano P. Roles of PDGF in animal development. Development. 2003;130:4769-84. (Pubitemid 37321862)
-
(2003)
Development
, vol.130
, Issue.20
, pp. 4769-4784
-
-
Hoch, R.V.1
Soriano, P.2
-
25
-
-
0032774661
-
Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle
-
Karlsson L, Bondjers C, Betsholtz C. Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle. Development. 1999;126:2611-21. (Pubitemid 29338623)
-
(1999)
Development
, vol.126
, Issue.12
, pp. 2611-2621
-
-
Karlsson, L.1
Bondjers, C.2
Betsholtz, C.3
-
26
-
-
6944220086
-
A specific requirement for PDGF-C in palate formation and PDGFR-α signaling
-
DOI 10.1038/ng1415
-
Ding H, Wu X, Bostrom H, et al. A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling. Nat Genet. 2004;36:1111-6. (Pubitemid 41184474)
-
(2004)
Nature Genetics
, vol.36
, Issue.10
, pp. 1111-1116
-
-
Ding, H.1
Wu, X.2
Bostrom, H.3
Kim, I.4
Wong, N.5
Tsoi, B.6
O'Rourke, M.7
Koh, G.Y.8
Soriano, P.9
Betsholtz, C.10
Hart, T.C.11
Marazita, M.L.12
Field, L.L.13
Tam, P.P.L.14
Nagy, A.15
-
27
-
-
0030808324
-
The PDGFα receptor is required for neural crest cell development and for normal patterning of the somites
-
Soriano P. The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites. Development. 1997;124:2691-700. (Pubitemid 27354815)
-
(1997)
Development
, vol.124
, Issue.14
, pp. 2691-2700
-
-
Soriano, P.1
-
28
-
-
15844370315
-
PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis
-
DOI 10.1016/S0092-8674(00)81270-2
-
Bostrom H, Willetts K, Pekny M, et al. PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell. 1996;85:863-73. (Pubitemid 26192137)
-
(1996)
Cell
, vol.85
, Issue.6
, pp. 863-873
-
-
Bostrom, H.1
Willetts, K.2
Pekny, M.3
Leveen, P.4
Lindahl, P.5
Hedstrand, H.6
Pekna, M.7
Hellstrom, M.8
Gebre-Medhin, S.9
Schalling, M.10
Nilsson, M.11
Kurland, S.12
Tornell, J.13
Heath, J.K.14
Betsholtz, C.15
-
29
-
-
0033832891
-
Abnormal gastrointestinal development in PDGF-A and PDGFR-(alpha) deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis
-
Karlsson L, Lindahl P, Heath JK, Betsholtz C. Abnormal gastrointestinal development in PDGF-A and PDGFR-(alpha) deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis. Development. 2000;127:3457-66.
-
(2000)
Development.
, vol.127
, pp. 3457-3466
-
-
Karlsson, L.1
Lindahl, P.2
Heath, J.K.3
Betsholtz, C.4
-
30
-
-
0030756325
-
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
-
DOI 10.1126/science.277.5323.242
-
Lindahl P, Johansson BR, Leveen P, Betsholtz C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science. 1997;277:242-5. (Pubitemid 27446080)
-
(1997)
Science
, vol.277
, Issue.5323
, pp. 242-245
-
-
Lindahl, P.1
Johansson, B.R.2
Leveen, P.3
Betsholtz, C.4
-
31
-
-
79958799319
-
Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling
-
Smith CL, Baek ST, Sung CY, Tallquist MD. Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling. Circ Res. 2011;108:e15-26.
-
(2011)
Circ Res.
, vol.108
-
-
Smith, C.L.1
Baek, S.T.2
Sung, C.Y.3
Tallquist, M.D.4
-
32
-
-
0032768156
-
Role of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
-
Hellstrom M, Kalen M, Lindahl P, et al. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development. 1999;126:3047-55. (Pubitemid 29378170)
-
(1999)
Development
, vol.126
, Issue.14
, pp. 3047-3055
-
-
Hellstrom, M.1
Kalen, M.2
Lindahl, P.3
Abramsson, A.4
Betsholtz, C.5
-
33
-
-
84859465056
-
In vivo identification of bipotential adipocyte progenitors recruited by beta3- adrenoceptor activation and high-fat feeding
-
Lee YH, Petkova AP, Mottillo EP, Granneman JG. In vivo identification of bipotential adipocyte progenitors recruited by beta3- adrenoceptor activation and high-fat feeding. Cell Metab. 2012;15:480-91.
-
(2012)
Cell Metab.
, vol.15
, pp. 480-491
-
-
Lee, Y.H.1
Petkova, A.P.2
Mottillo, E.P.3
Granneman, J.G.4
-
34
-
-
53549130485
-
White fat progenitor cells reside in the adipose vasculature
-
Tang W, Zeve D, Suh JM, et al. White fat progenitor cells reside in the adipose vasculature. Science. 2008;322:583-6.
-
(2008)
Science
, vol.322
, pp. 583-586
-
-
Tang, W.1
Zeve, D.2
Suh, J.M.3
-
35
-
-
75949096894
-
Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis
-
Joe AW, Yi L, Natarajan A, et al. Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis. Nat Cell Biol. 2010;12:153-63.
-
(2010)
Nat Cell Biol.
, vol.12
, pp. 153-163
-
-
Joe, A.W.1
Yi, L.2
Natarajan, A.3
-
36
-
-
75949130333
-
Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle
-
Uezumi A, Fukada S, Yamamoto N, et al. Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle. Nat Cell Biol. 2010;12:143-52.
-
(2010)
Nat Cell Biol.
, vol.12
, pp. 143-152
-
-
Uezumi, A.1
Fukada, S.2
Yamamoto, N.3
-
37
-
-
84864722077
-
Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury
-
Dulauroy S, Di Carlo SE, Langa F, et al. Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury. Nat Med. 2012;18:1262-70.
-
(2012)
Nat Med.
, vol.18
, pp. 1262-1270
-
-
Dulauroy, S.1
Di Carlo, S.E.2
Langa, F.3
-
38
-
-
77951732927
-
Decreased lymphatic vessel counts in patients with systemic sclerosis: Association with fingertip ulcers
-
Akhmetshina A, Beer J, Zwerina K, et al. Decreased lymphatic vessel counts in patients with systemic sclerosis: association with fingertip ulcers. Arthritis Rheum. 2010;62:1513-22.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 1513-1522
-
-
Akhmetshina, A.1
Beer, J.2
Zwerina, K.3
-
39
-
-
84862491030
-
Aberrant mural cell recruitment to lymphatic vessels and impaired lymphatic drainage in a murine model of pulmonary fibrosis
-
Meinecke AK, Nagy N, Lago GD, et al. Aberrant mural cell recruitment to lymphatic vessels and impaired lymphatic drainage in a murine model of pulmonary fibrosis. Blood. 2012;119:5931-42.
-
(2012)
Blood.
, vol.119
, pp. 5931-5942
-
-
Meinecke, A.K.1
Nagy, N.2
Lago, G.D.3
-
40
-
-
84863632660
-
Follicular dendritic cells emerge from ubiquitous perivascular precursors
-
Krautler NJ, Kana V, Kranich J, et al. Follicular dendritic cells emerge from ubiquitous perivascular precursors. Cell. 2012;150:194-206.
-
(2012)
Cell.
, vol.150
, pp. 194-206
-
-
Krautler, N.J.1
Kana, V.2
Kranich, J.3
-
41
-
-
0042845995
-
Transgenic overexpression of platelet-derived growth factor-C in the mouse heart induces cardiac fibrosis, hypertrophy, and dilated cardiomyopathy
-
Ponten A, Li X, Thoren P, et al. Transgenic overexpression of platelet-derived growth factor-C in the mouse heart induces cardiac fibrosis, hypertrophy, and dilated cardiomyopathy. Am J Pathol. 2003;163:673-82. (Pubitemid 36909428)
-
(2003)
American Journal of Pathology
, vol.163
, Issue.2
, pp. 673-682
-
-
Ponten, A.1
Li, X.2
Thoren, P.3
Aase, K.4
Sjoblom, T.5
Ostman, A.6
Eriksson, U.7
-
42
-
-
27944503433
-
Platelet-derived growth factor D induces cardiac fibrosis and proliferation of vascular smooth muscle cells in heart-specific transgenic mice
-
DOI 10.1161/01.RES.0000190590.31545.d4
-
Ponten A, Folestad EB, Pietras K, Eriksson U. Platelet-derived growth factor D induces cardiac fibrosis and proliferation of vascular smooth muscle cells in heart-specific transgenic mice. Circ Res. 2005;97:1036-45. (Pubitemid 41668917)
-
(2005)
Circulation Research
, vol.97
, Issue.10
, pp. 1036-1045
-
-
Ponten, A.1
Folestad, E.B.2
Pietras, K.3
Eriksson, U.4
-
43
-
-
20044385758
-
Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma
-
DOI 10.1073/pnas.0409722102
-
Campbell JS, Hughes SD, Gilbertson DG, et al. Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma. Proc Natl Acad Sci USA. 2005;102:3389-94. (Pubitemid 40328055)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.9
, pp. 3389-3394
-
-
Campbell, J.S.1
Hughes, S.D.2
Gilbertson, D.G.3
Palmer, T.E.4
Holdren, M.S.5
Haran, A.C.6
Odell, M.M.7
Bauer, R.L.8
Ren, H.-P.9
Haugen, H.S.10
Yeh, M.M.11
Fausto, N.12
-
44
-
-
79958239247
-
PDGFRbeta signaling regulates mural cell plasticity and inhibits fat development
-
Olson LE, Soriano P. PDGFRbeta Signaling Regulates Mural Cell Plasticity and Inhibits Fat Development. Dev Cell. 2011;20:815-26.
-
(2011)
Dev Cell.
, vol.20
, pp. 815-826
-
-
Olson, L.E.1
Soriano, P.2
-
45
-
-
1642297200
-
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression
-
DOI 10.1038/nature02382
-
Wang Z, Wang DZ, Hockemeyer D, et al. Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature. 2004;428:185-9. (Pubitemid 38374315)
-
(2004)
Nature
, vol.428
, Issue.6979
, pp. 185-189
-
-
Wang, Z.1
Wang, D.-Z.2
Hockemeyer, D.3
McAnally, J.4
Nordheim, A.5
Olson, E.N.6
-
46
-
-
37349045796
-
CXCL10 (α) and CCL2 (β) chemokines in systemic sclerosis - A longitudinal study
-
DOI 10.1093/rheumatology/kem313
-
Antonelli A, Ferri C, Fallahi P, et al. CXCL10 (alpha) and CCL2 (beta) chemokines in systemic sclerosis-a longitudinal study. Rheumatol (Oxford). 2008;47:45-9. (Pubitemid 350286260)
-
(2008)
Rheumatology
, vol.47
, Issue.1
, pp. 45-49
-
-
Antonelli, A.1
Ferri, C.2
Fallahi, P.3
Ferrari, S.M.4
Giuggioli, D.5
Colaci, M.6
Manfredi, A.7
Frascerra, S.8
Franzoni, F.9
Galetta, F.10
Ferrannini, E.11
-
47
-
-
0036007120
-
An allelic series at the PDGFαR locus indicates unequal contributions of distinct signaling pathways during development
-
DOI 10.1016/S1534-5807(01)00103-4
-
Klinghoffer RA, Hamilton TG, Hoch R, Soriano P. An allelic series at the PDGFalphaR locus indicates unequal contributions of distinct signaling pathways during development. Dev Cell. 2002;2:103-13. (Pubitemid 34065910)
-
(2002)
Developmental Cell
, vol.2
, Issue.1
, pp. 103-113
-
-
Klinghoffer, R.A.1
Hamilton, T.G.2
Hoch, R.3
Soriano, P.4
-
48
-
-
2342419356
-
Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development
-
Tallquist MD, French WJ, Soriano P. Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. PLoS Biol. 2003;1:E52.
-
(2003)
PLoS Biol.
, vol.1
-
-
Tallquist, M.D.1
French, W.J.2
Soriano, P.3
-
49
-
-
33846209989
-
Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis
-
DOI 10.1002/art.22314
-
Distler JH, Jungel A, Huber LC, et al. Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. Arthritis Rheum. 2007;56:311-22. (Pubitemid 46106205)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.1
, pp. 311-322
-
-
Distler, J.H.W.1
Jungel, A.2
Huber, L.C.3
Schulze-Horsel, U.4
Zwerina, J.5
Gay, R.E.6
Michel, B.A.7
Hauser, T.8
Schett, G.9
Gay, S.10
Distler, O.11
-
50
-
-
58249120518
-
Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of established fibrosis
-
Akhmetshina A, Venalis P, Dees C, et al. Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of established fibrosis. Arthritis Rheum. 2009;60:219-24.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 219-224
-
-
Akhmetshina, A.1
Venalis, P.2
Dees, C.3
-
51
-
-
80155204477
-
A one-year, phase I/IIa, open-label pilot trial of imatinib mesylate in the treatment of systemic sclerosis-associated active interstitial lung disease
-
Khanna D, Saggar R, Mayes MD, et al. A one-year, phase I/IIa, open-label pilot trial of imatinib mesylate in the treatment of systemic sclerosis-associated active interstitial lung disease. Arthritis Rheum. 2011;63:3540-6.
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 3540-3546
-
-
Khanna, D.1
Saggar, R.2
Mayes, M.D.3
-
52
-
-
80155206225
-
Imatinib in active diffuse cutaneous systemic sclerosis: Results of a six-month, randomized, double-blind, placebo-controlled, proof-of-concept pilot study at a single center
-
Pope J, McBain D, Petrlich L, et al. Imatinib in active diffuse cutaneous systemic sclerosis: results of a six-month, randomized, double-blind, placebo-controlled, proof-of-concept pilot study at a single center. Arthritis Rheum. 2011;63:3547-51.
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 3547-3551
-
-
Pope, J.1
McBain, D.2
Petrlich, L.3
-
53
-
-
79955860261
-
Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: Results of a 1-year, phase IIa, single-arm, open-label clinical trial
-
Spiera RF, Gordon JK, Mersten JN, et al. Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 1-year, phase IIa, single-arm, open-label clinical trial. Ann Rheum Dis. 2011;70:1003-9.
-
(2011)
Ann Rheum Dis.
, vol.70
, pp. 1003-1009
-
-
Spiera, R.F.1
Gordon, J.K.2
Mersten, J.N.3
-
54
-
-
84861824342
-
Sunitinib inhibits the phosphorylation of platelet-derived growth factor receptor beta in the skin of mice with scleroderma-like features and prevents the development of the disease
-
Kavian N, Servettaz A, Marut W, et al. Sunitinib inhibits the phosphorylation of platelet-derived growth factor receptor beta in the skin of mice with scleroderma-like features and prevents the development of the disease. Arthritis Rheum. 2012;64:1990-2000.
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 1990-2000
-
-
Kavian, N.1
Servettaz, A.2
Marut, W.3
-
55
-
-
74949085470
-
Cardiac mast cells cause atrial fibrillation through PDGF-A-mediated fibrosis in pressure-overloaded mouse hearts
-
Liao CH, Akazawa H, Tamagawa M, et al. Cardiac mast cells cause atrial fibrillation through PDGF-A-mediated fibrosis in pressure-overloaded mouse hearts. J Clin Invest. 2010;120:242-53.
-
(2010)
J Clin Invest.
, vol.120
, pp. 242-253
-
-
Liao, C.H.1
Akazawa, H.2
Tamagawa, M.3
-
56
-
-
34047123693
-
Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling
-
DOI 10.1016/j.cardiores.2006.11.028, PII S0008636306005165
-
Zymek P, Nah DY, Bujak M, et al. Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling. Cardiovasc Res. 2007;74:313-22. (Pubitemid 46517506)
-
(2007)
Cardiovascular Research
, vol.74
, Issue.2
, pp. 313-322
-
-
Zymek, P.1
Nah, D.-Y.2
Bujak, M.3
Ren, G.4
Koerting, A.5
Leucker, T.6
Huebener, P.7
Taffet, G.8
Entman, M.9
Frangogiannis, N.G.10
-
57
-
-
41849133613
-
Phenotypical and functional characteristics of in vitro expanded bone marrow mesenchymal stem cells from patients with systemic sclerosis
-
DOI 10.1136/ard.2007.071233
-
Larghero J, Farge D, Braccini A, et al. Phenotypical and functional characteristics of in vitro expanded bone marrow mesenchymal stem cells from patients with systemic sclerosis. Ann Rheum Dis. 2008;67:443-9. (Pubitemid 351498421)
-
(2008)
Annals of the Rheumatic Diseases
, vol.67
, Issue.4
, pp. 443-449
-
-
Larghero, J.1
Farge, D.2
Braccini, A.3
Lecourt, S.4
Scherberich, A.5
Fois, E.6
Verrecchia, F.7
Daikeler, T.8
Gluckman, E.9
Tyndall, A.10
Bocelli-Tyndall, C.11
|