The fibroblast integrin α11β1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation

Journal of Biological Chemistry

Volumn 285, Issue 14, 2010, Pages 10434-10445

  Carracedo, Sergio ^a   Lu, Ning ^a   Popova, Svetlana N ^a   Jonsson, Roland ^a   Eckes, Beate ^b   Gullberg, Donald ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN GELS; COLLAGEN RECEPTORS; CYTOCHALASIN D; CYTOSKELETONS; EXTRACELLULAR MATRICES; FIBROTIC TISSUE; HUMAN CORNEAL; IN-CELL; INTEGRINS; MECHANICAL STRESS; MEDIATED INTERACTION; MOUSE EMBRYONIC FIBROBLASTS; MYOFIBROBLASTS; PROTEIN LEVEL; SMALL INTERFERING RNA; SMOOTH MUSCLE ACTINS; UP-REGULATION;

CELL CULTURE; COLLAGEN; FIBROBLASTS; GELS; GLYCOPROTEINS; PHOSPHORYLATION; RNA; STRESSES;

TISSUE;

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ACTIVIN A; ACTIVIN RECEPTOR LIKE KINASE 4; ACTIVIN RECEPTOR LIKE KINASE 7; ALPHA SMOOTH MUSCLE ACTIN; ALPHA11BETA1 INTEGRIN; COLLAGEN GEL; COLLAGEN RECEPTOR; CYTOCHALASIN D; MESSENGER RNA; PROTEIN SERINE THREONINE KINASE; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; ACTIN; ACTIVIN; ALPHA SMA PROTEIN, MOUSE; COLLAGEN; INTEGRIN; INTEGRIN ALPHA11BETA1; NODAL SIGNALING PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STRESS; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; FIBROBLAST; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MOUSE; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANIMAL EMBRYO; CELL CULTURE; CORNEA; CULTURE TECHNIQUE; CYTOLOGY; CYTOSKELETON; DRUG ANTAGONISM; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; WESTERN BLOTTING;

ACTINS; ACTIVINS; ANIMALS; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; COLLAGEN; CORNEA; CYTOSKELETON; EMBRYO, MAMMALIAN; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INTEGRINS; MICE; MUSCLE, SKELETAL; NODAL SIGNALING LIGANDS; PHENOTYPE; RECEPTORS, COLLAGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77951224978     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.078766     Document Type: Article

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