Proinflammatory chemokine induction in keratocytes and inflammatory cell infiltration into the cornea

Investigative Ophthalmology and Visual Science

Volumn 42, Issue 12, 2001, Pages 2795-2803

  Hong, J W ^a   Liu, J J ^a   Lee, J S ^a   Mohan, R R ^a   Woods, D J ^a   He, Y G ^a   Wilson, S E ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR; CYTOKINE; CYTOKINE RECEPTOR; EOSIN; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GRANULOCYTE COLONY STIMULATING FACTOR; HEMATOXYLIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA CELL; CORNEA EPITHELIUM; CORNEA INJURY; CORNEA STROMA; CYTOKINE PRODUCTION; DNA MICROARRAY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INFLAMMATION; INFLAMMATORY CELL; INFLAMMATORY INFILTRATE; MACROPHAGE; MICROINJECTION; MONOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIBONUCLEASE PROTECTION ASSAY; STAINING; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL MOVEMENT; CHEMOKINE CCL2; CHEMOKINES; CORNEAL STROMA; FIBROBLASTS; GENE EXPRESSION PROFILING; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-1; MACROPHAGES; MONOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, CHEMOKINE; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0034766086     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Stromal-epithelial interactions in the cornea
2. Stromal-epithelial interactions in the cornea
3. The corneal wound healing response: Cytokine-mediated interaction of the epithelium, stroma, and inflammatory cells
4. Epidermal growth factor, transforming growth factor alpha, transforming growth factor beta, acidic fibroblast growth factor, basic fibroblast growth factor, and interleukin-1 proteins in the cornea
5. IL-1 upregulates keratinocyte growth factor and hepatocyte growth factor mRNA and protein production by cultured stromal fibroblast cells: Interleukin-1 beta expression in the cornea
6. Epithelial injury induces keratocyte apoptosis: Hypothesized role for the interleukin-1 system in the modulation of corneal tissue organization and wound healing
7. Apoptosis in the cornea: Further characterization of FasFas ligand system
8. Effect of epidermal growth factor, hepatocyte growth factor, and keratinocyte growth factor, on proliferation, motility, and differentiation of human corneal epithelial cells
9. Regulation of paracrine cytokine balance controlling collagenase synthesis by corneal cells
10. Competence for collagenase gene expression by tissue fibroblasts requires activation of an interleukin 1 alpha autocrine loop
11. Effect of PDGF, IL-1 alpha, and BMP2/4 on corneal fibroblast chemotaxis: Expression of the platelet-derived growth factor system in the cornea
12. Modulation of TNF-αinduced apoptosis in corneal fibroblasts by transcription factor NF-kb
13. Lacrimal gland HGF, KGF, and EGF mRNA levels increase after corneal epithelial wounding
14. Keratocyte apoptosis after corneal surgery
15. The second extracellular loop of CCR5 is the major determinant of ligand specificity
16. Recombinant human granulocyte colony-stimulating factor: Effects on normal and leukemic myeloid cells
17. Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor
18. Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors
19. Monocyte chemoattractant protein-2 is a potent agonist of CCR2B
20. Chemokines: Signal lamps for trafficking of T and B cells for development and effector function
21. The detection of a novel neutrophil-activating peptide (ENA-78) using a sensitive ELISA
22. IL-8 and NAP-2 differ in their capacities to bind and chemoattract 293 cells transfected with either IL-8 receptor type A or type B
23. Neutrophil-activating peptides NAP-2 and IL-8 bind to the same sites on neutrophils but interact in different ways: Discrepancies in binding affinities, receptor densities, and biologic effects
24. A mixed-charge pair in human interleukin 4 dominates high-affinity interaction with the receptor alpha chain
25. Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities
26. Interleukin-4 receptors on human blood mononuclear cells
27. Inflammatory response in the early stages of wound healing after excimer laser keratectomy
28. Proinflammatory cytokines induce RANTES and MCP-1 synthesis in human corneal keratocytes but not in corneal epithelial cells: Beta-chemokine synthesis in corneal cells
29. Proteoglycan synthesis by bovine keratocytes and corneal fibroblasts: Maintenance of the keratocyte phenotype in culture
30. Keratocyte and fibroblast phenotypes in the repairing cornea