-
1
-
-
61749097816
-
TGF-b superfamily signaling in embryonic development and homeostasis
-
Wu, M. Y. & Hill, C. S. TGF-b superfamily signaling in embryonic development and homeostasis. Dev. Cell 16, 329-343 (2009).
-
(2009)
Dev. Cell
, vol.16
, pp. 329-343
-
-
Wu, M.Y.1
Hill, C.S.2
-
2
-
-
44449085619
-
-
(edsDerynck, R. & Miyazono, K.) Ch. 2 (Cold Spring Harbor Laboratory Press
-
Derynck, R. & Miyazono, K. in The TGF-b Family (edsDerynck, R. & Miyazono, K.) Ch. 2, 29-43 (Cold Spring Harbor Laboratory Press, 2008).
-
(2008)
The TGF-b Family
, pp. 29-43
-
-
Derynck, R.1
Miyazono, K.2
-
3
-
-
0034604110
-
Role of transforming growth factor in human disease
-
DOI 10.1056/NEJM200005043421807
-
Blobe, G. C., Schiemann, W. P. & Lodish, H. F.Role of transforminggrowth factor b in human disease. N. Engl. J. Med. 342, 1350-1358 (2000). (Pubitemid 30408720)
-
(2000)
New England Journal of Medicine
, vol.342
, Issue.18
, pp. 1350-1358
-
-
Blobe, G.C.1
Schiemann, W.P.2
Lodish, H.F.3
-
4
-
-
0025373853
-
Requirement for activin A and transforming growth factor-b 1 pro-regions in homodimer assembly
-
Gray, A. M. & Mason, A. J. Requirement for activin A and transforming growth factor-b 1 pro-regions in homodimer assembly. Science 247, 1328-1330 (1990).
-
(1990)
Science
, vol.247
, pp. 1328-1330
-
-
Gray, A.M.1
Mason, A.J.2
-
5
-
-
2942653435
-
Integrin aVb6-mediated activation of latent TGF-b requires the latent TGF-b binding protein-1
-
Annes, J. P., Chen, Y., Munger, J. S. & Rifkin, D. B. Integrin aVb6-mediated activation of latent TGF-b requires the latent TGF-b binding protein-1. J. Cell Biol. 165, 723-734 (2004).
-
(2004)
J. Cell Biol.
, vol.165
, pp. 723-734
-
-
Annes, J.P.1
Chen, Y.2
Munger, J.S.3
Rifkin, D.B.4
-
6
-
-
72449194274
-
Biogenesis and function of fibrillin assemblies
-
Ramirez, F. & Sakai, L. Y. Biogenesis and function of fibrillin assemblies. Cell Tissue Res. 339, 71-82 (2010).
-
(2010)
Cell Tissue Res.
, vol.339
, pp. 71-82
-
-
Ramirez, F.1
Sakai, L.Y.2
-
7
-
-
33947265169
-
Absence of integrin-mediated TGF1 activation in vivo recapitulates the phenotype of TGF1-null mice
-
DOI 10.1083/jcb.200611044
-
Yang, Z. et al. Absence of integrin-mediated TGFb1 activation in vivo recapitulates the phenotype of TGFb1-null mice. J. Cell Biol. 176, 787-793 (2007). (Pubitemid 46425539)
-
(2007)
Journal of Cell Biology
, vol.176
, Issue.6
, pp. 787-793
-
-
Yang, Z.1
Mu, Z.2
Dabovic, B.3
Jurukovski, V.4
Yu, D.5
Sung, J.6
Xiong, X.7
Munger, J.S.8
-
8
-
-
49049110677
-
Integrins and the activation of latent transforming growth factor b1-an intimate relationship
-
Wipff, P. J. & Hinz, B. Integrins and the activation of latent transforming growth factor b1-an intimate relationship. Eur. J. Cell Biol. 87, 601-615 (2008).
-
(2008)
Eur. J. Cell Biol.
, vol.87
, pp. 601-615
-
-
Wipff, P.J.1
Hinz, B.2
-
9
-
-
61949349656
-
Mice that lack activity of aVb6- andaVb8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice
-
Aluwihare, P. et al. Mice that lack activity of aVb6- andaVb8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice. J. Cell Sci. 122, 227-232 (2009).
-
(2009)
J. Cell Sci.
, vol.122
, pp. 227-232
-
-
Aluwihare, P.1
-
10
-
-
0033524949
-
The integrin v6 binds and activates latent TGF1: A mechanism for regulating pulmonary inflammation and fibrosis
-
DOI 10.1016/S0092-8674(00)80545-0
-
Munger, J. S. et al. The integrin aVb6 binds and activates latent TGF b1: A mechanism for regulating pulmonary inflammation and fibrosis. Cell 96, 319-328 (1999). (Pubitemid 29077586)
-
(1999)
Cell
, vol.96
, Issue.3
, pp. 319-328
-
-
Munger, J.S.1
Huang, X.2
Kawakatsu, H.3
Griffiths, M.J.D.4
Dalton, S.L.5
Wu, J.6
Pittet, J.-F.7
Kaminski, N.8
Garat, C.9
Matthay, M.A.10
Rifkin, D.B.11
Sheppard, D.12
-
11
-
-
57749085683
-
Perturbation of transforming growth factor (TGF)-b1 association with latent TGF-b binding protein yields inflammation and tumors
-
Yoshinaga, K. et al. Perturbation of transforming growth factor (TGF)-b1 association with latent TGF-b binding protein yields inflammation and tumors. Proc. Natl Acad. Sci. USA 105, 18758-18763 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 18758-18763
-
-
Yoshinaga, K.1
-
12
-
-
56649103902
-
Searching protein structure databases with DaliLite v.3
-
DOI 10.1093/bioinformatics/btn507
-
Holm, L., Kaariainen, S., Rosenstrom, P. & Schenkel, A. Searching protein structure databases with DaliLite v.3. Bioinformatics 24, 2780-2781 (2008). (Pubitemid 352722625)
-
(2008)
Bioinformatics
, vol.24
, Issue.23
, pp. 2780-2781
-
-
Holm, L.1
Kaariainen, S.2
Rosenstrom, P.3
Schenkel, A.4
-
13
-
-
0027122245
-
Crystal structure of transforming growth factor-b2: An unusual fold for the superfamily
-
Daopin, S., Piez, K. A., Ogawa, Y. & Davies, D. R. Crystal structure of transforming growth factor-b2: an unusual fold for the superfamily. Science 257, 369-373 (1992).
-
(1992)
Science
, vol.257
, pp. 369-373
-
-
Daopin, S.1
Piez, K.A.2
Ogawa, Y.3
Davies, D.R.4
-
14
-
-
0026633842
-
An unusual feature revealed by the crystal structure at 2.2A? resolution of humantransforming growth factor-b2
-
Schlunegger, M. P. & Grutter, M. G. An unusual feature revealed by the crystal structure at 2.2A? resolution of humantransforming growth factor-b2. Nature 358, 430-434 (1992).
-
(1992)
Nature
, vol.358
, pp. 430-434
-
-
Schlunegger, M.P.1
Grutter, M.G.2
-
15
-
-
77952005098
-
Ternary complex of transforming growthfactor-b1reveals isoformspecific ligand recognition and receptor recruitment in the superfamily
-
Radaev, S. et al.Ternary complex of transforming growthfactor-b1reveals isoformspecific ligand recognition and receptor recruitment in the superfamily. J. Biol. Chem. 285, 14806-14814 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 14806-14814
-
-
Radaev, S.1
-
16
-
-
0025324976
-
The pro domain of pre-pro-transforming growth factor 1 when independently expressed is a functional binding protein for the mature growth factor
-
DOI 10.1021/bi00481a014
-
Gentry, L. E. & Nash, B. W. The pro domain of pre-pro-transforming growth factor b1 when independently expressed is a functional binding protein for the mature growth factor. Biochemistry 29, 6851-6857 (1990). (Pubitemid 20225485)
-
(1990)
Biochemistry
, vol.29
, Issue.29
, pp. 6851-6857
-
-
Gentry, L.E.1
Nash, B.W.2
-
17
-
-
1542327546
-
Mutations of the anti-mullerian hormone gene in patients with persistent Mullerian duct syndrome: Biosynthesis, secretion, and processing of the abnormal proteins and analysis using a three-dimensional model
-
DOI 10.1210/me.2003-0358
-
Belville, C. et al. Mutations of the anti-Mü llerian hormone gene in patients with persistent Mü llerian duct syndrome: biosynthesis, secretion, and processing of the abnormal proteins and analysis using a three-dimensional model. Mol. Endocrinol. 18, 708-721 (2004). (Pubitemid 38328214)
-
(2004)
Molecular Endocrinology
, vol.18
, Issue.3
, pp. 708-721
-
-
Belville, C.1
Van Vlijmen, H.2
Ehrenfels, C.3
Pepinsky, B.4
Rezaie, A.R.5
Picard, J.-Y.6
Josso, N.7
Di Clemente, N.8
Cate, R.L.9
-
18
-
-
77952784624
-
Two distinct regions of latency-associated peptide coordinate stability of the latent transforming growth factor-b1 complex
-
Walton, K. L. et al. Two distinct regions of latency-associated peptide coordinate stability of the latent transforming growth factor-b1 complex. J. Biol. Chem. 285, 17029-17037 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 17029-17037
-
-
Walton, K.L.1
-
19
-
-
67349187409
-
Bone morphogenetic protein heterodimers assemble heteromeric type i receptor complexes to pattern the dorsoventral axis
-
Little, S. C. & Mullins, M. C. Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis. Nature Cell Biol. 11, 637-643 (2009).
-
(2009)
Nature Cell Biol.
, vol.11
, pp. 637-643
-
-
Little, S.C.1
Mullins, M.C.2
-
20
-
-
0242383972
-
Solution structure of the third TB domain from LTBP1 provides insight into assembly of the large latent complex that sequesters latent TGF
-
DOI 10.1016/j.jmb.2003.09.053
-
Lack, J. et al. Solutionstructure of the thirdTBdomain fromLTBP1provides insight into assembly of the large latent complex that sequesters latent TGF-b. J. Mol. Biol. 334, 281-291 (2003). (Pubitemid 37357267)
-
(2003)
Journal of Molecular Biology
, vol.334
, Issue.2
, pp. 281-291
-
-
Lack, J.1
O'Leary, J.M.2
Knott, V.3
Yuan, X.4
Rifkin, D.B.5
Handford, P.A.6
Downing, A.K.7
-
21
-
-
9644291591
-
Amino acid requirements for formation of the TGF-latent TGF- binding protein complexes
-
DOI 10.1016/j.jmb.2004.10.039, PII S0022283604013312
-
Chen, Y. et al. Amino acid requirements for formation of the TGF-b-latent TGF-b binding protein complexes. J. Mol. Biol. 345, 175-186 (2005). (Pubitemid 39572834)
-
(2005)
Journal of Molecular Biology
, vol.345
, Issue.1
, pp. 175-186
-
-
Chen, Y.1
Ali, T.2
Todorovic, V.3
O'Leary, J.M.4
Kristina Downing, A.5
Rifkin, D.B.6
-
22
-
-
34247891506
-
Structural basis of integrin regulation and signaling
-
DOI 10.1146/annurev.immunol.25.022106.141618
-
Luo, B.-H., Carman, C. V. & Springer, T. A. Structural basis of integrin regulation and signaling. Annu. Rev. Immunol. 25, 619-647 (2007). (Pubitemid 46697919)
-
(2007)
Annual Review of Immunology
, vol.25
, pp. 619-647
-
-
Luo, B.-H.1
Carman, C.V.2
Springer, T.A.3
-
23
-
-
33846940059
-
Mechanical unfolding of proteins: Insights into biology, structure and folding
-
DOI 10.1016/j.sbi.2007.01.006, PII S0959440X07000073, Foldinf and Binding / Protein-Nucleic Interactions
-
Forman, J. R. & Clarke, J. Mechanical unfolding of proteins: insights into biology, structure and folding. Curr. Opin. Struct. Biol. 17, 58-66 (2007). (Pubitemid 46240817)
-
(2007)
Current Opinion in Structural Biology
, vol.17
, Issue.1
, pp. 58-66
-
-
Forman, J.R.1
Clarke, J.2
-
24
-
-
30744450220
-
Camurati-Engelmann disease: Review of the clinical, radiological, and molecular data of 24 families and implications for diagnosis and treatment
-
DOI 10.1136/jmg.2005.033522
-
Janssens, K. et al. Camurati-Engelmann disease: reviewof the clinical, radiological, and molecular data of 24 families and implications for diagnosis and treatment. J. Med. Genet. 43, 1-11 (2005). (Pubitemid 43099989)
-
(2006)
Journal of Medical Genetics
, vol.43
, Issue.1
, pp. 1-11
-
-
Janssens, K.1
Vanhoenacker, F.2
Bonduelle, M.3
Verbruggen, L.4
Van Maldergem, L.5
Ralston, S.6
Guanabens, N.7
Migone, N.8
Wientroub, S.9
Divizia, M.T.10
Bergmann, C.11
Bennett, C.12
Simsek, S.13
Melancon, S.14
Cundy, T.15
Van Hul, W.16
-
25
-
-
66149084397
-
A common biosynthetic pathway governs the dimerization and secretion of inhibin andrelated transforming growth factor b (TGFb) ligands
-
Walton, K. L. et al. A common biosynthetic pathway governs the dimerization and secretion of inhibin andrelated transforming growth factor b (TGFb) ligands. J. Biol. Chem. 284, 9311-9320 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 9311-9320
-
-
Walton, K.L.1
-
26
-
-
43749111385
-
Identification of a novel pool of extracellular pro-myostatin in skeletal muscle
-
Anderson, S. B., Goldberg, A. L. & Whitman, M. Identification of a novel pool of extracellular pro-myostatin in skeletal muscle. J. Biol. Chem. 283, 7027-7035 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 7027-7035
-
-
Anderson, S.B.1
Goldberg, A.L.2
Whitman, M.3
-
27
-
-
46649104796
-
Targeting of bonemorphogenetic protein growth factor complexes to fibrillin
-
Sengle, G. et al. Targeting of bonemorphogenetic protein growth factor complexes to fibrillin. J. Biol. Chem. 283, 13874-13888 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13874-13888
-
-
Sengle, G.1
-
28
-
-
0035498979
-
The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor
-
Cui, Y. et al. The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor. Genes Dev. 15, 2797-2802 (2001). (Pubitemid 33042050)
-
(2001)
Genes and Development
, vol.15
, Issue.21
, pp. 2797-2802
-
-
Cui, Y.1
Hackenmiller, R.2
Berg, L.3
Jean, F.4
Nakayama, T.5
Thomas, G.6
Christian, J.L.7
-
29
-
-
53549118575
-
Cripto recruits FurinandPACE4andcontrolsNodal trafficking during proteolytic maturation
-
Blanchet, M. H. et al. Cripto recruits FurinandPACE4andcontrolsNodal trafficking during proteolytic maturation. EMBO J. 27, 2580-2591 (2008).
-
(2008)
EMBO J.
, vol.27
, pp. 2580-2591
-
-
Blanchet, M.H.1
-
30
-
-
0027408040
-
Mullerian inhibiting substance requires its N-terminal domain for maintenance of biological activity, a novel finding within the transforming growth factor- superfamily
-
DOI 10.1210/me.7.2.247
-
Wilson, C. A. et al.Mü llerianinhibitingsubstance requires its N-terminal domainfor maintenance of biological activity, a novel finding within the transforming growth factor-b superfamily. Mol. Endocrinol. 7, 247-257 (1993). (Pubitemid 23066868)
-
(1993)
Molecular Endocrinology
, vol.7
, Issue.2
, pp. 247-257
-
-
Wilson, C.A.1
Di Clemente, N.2
Ehrenfels, C.3
Pepinsky, R.B.4
Josso, N.5
Vigier, B.6
Cate, R.L.7
-
31
-
-
0035877662
-
Lefty proteins exhibit unique processing and activate the MAPK pathway
-
Ulloa, L. et al. Lefty proteins exhibit unique processing and activate the MAPK pathway. J. Biol. Chem. 276, 21387-21396 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21387-21396
-
-
Ulloa, L.1
-
32
-
-
0035543198
-
One-step purification of recombinant proteins using a nanomolar-affinity streptavidin-binding peptide, the SBP-tag
-
DOI 10.1006/prep.2001.1515
-
Keefe, A. D., Wilson, D. S., Seelig, B. & Szostak, J. W. One-step purification of recombinant proteins using a nanomolar-affinity streptavidin-binding peptide, the SBP-Tag. Protein Expr. Purif. 23, 440-446 (2001). (Pubitemid 34067367)
-
(2001)
Protein Expression and Purification
, vol.23
, Issue.3
, pp. 440-446
-
-
Keefe, A.D.1
Wilson, D.S.2
Seelig, B.3
Szostak, J.W.4
-
33
-
-
4444227987
-
Overexpression of human transforming growth factor-1 using a recombinant CHO cell expression system
-
DOI 10.1016/j.pep.2003.06.001, PII S1046592804001986
-
Zou, Z.& Sun, P. D. Overexpression of human transforming growth factor-b1using a recombinant CHO cell expression system. Protein Expr. Purif. 37, 265-272 (2004). (Pubitemid 39187961)
-
(2004)
Protein Expression and Purification
, vol.37
, Issue.2
, pp. 265-272
-
-
Zou, Z.1
Sun, P.D.2
-
34
-
-
0023429489
-
Type 1 transforming growth factor beta: Amplified expression and secretion of mature and precursor polypeptides in Chinese hamster ovary cells
-
Gentry, L. E. et al. Type 1 transforming growth factor beta: amplified expression and secretion of mature and precursor polypeptides in Chinese hamster ovary cells. Mol. Cell. Biol. 7, 3418-3427 (1987).
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 3418-3427
-
-
Gentry, L.E.1
-
35
-
-
0026793735
-
Site-directed mutagenesis of glycosylation sites in the transforming growth factor-beta 1 (TGF beta 1) and TGF beta 2 (414) precursors and of cysteine residues within mature TGF beta 1: Effects on secretion and bioactivity
-
Brunner, A. M. et al. Site-directed mutagenesis of glycosylation sites in the transforming growth factor-beta 1 (TGF beta 1) and TGF beta 2 (414) precursors and of cysteine residues within mature TGF beta 1: effects on secretion and bioactivity. Mol. Endocrinol. 6, 1691-1700 (1992).
-
(1992)
Mol. Endocrinol.
, vol.6
, pp. 1691-1700
-
-
Brunner, A.M.1
-
36
-
-
32944467057
-
Post-crystallization treatments for improving diffraction quality of protein crystals
-
DOI 10.1107/S0907444905019451
-
Heras, B. & Martin, J. L. Post-crystallization treatments for improving diffraction quality of protein crystals. Acta Crystallogr. D 61, 1173-1180 (2005). (Pubitemid 43961288)
-
(2005)
Acta Crystallographica Section D: Biological Crystallography
, vol.61
, Issue.9
, pp. 1173-1180
-
-
Heras, B.1
Martin, J.L.2
-
37
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
DOI 10.1016/S0076-6879(97)76066-X
-
Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307-326 (1997). (Pubitemid 27085611)
-
(1997)
Methods in Enzymology
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
38
-
-
0038786304
-
-
eds Rossmann, M. G. & Arnold, E. V. Ch. 25.2.9 XDS Springer
-
Kabsch, W. in International Tables for Crystallography, Vol. F: Crystallography of Biological Macromolecules (eds Rossmann, M. G. & Arnold, E. V.) Ch. 25.2.9 XDS, 730-734 (Springer, 2001).
-
(2001)
International Tables for Crystallography, Vol. F: Crystallography of Biological Macromolecules
, pp. 730-734
-
-
Kabsch, W.1
-
39
-
-
14244272868
-
PHENIX: Building new software for automated crystallographic structure determination
-
DOI 10.1107/S0907444902016657
-
Adams, P. D. et al. PHENIX: building new software for automated crystallographic structure determination. Acta Crystallogr. D 58, 1948-1954 (2002). (Pubitemid 35337293)
-
(2002)
Acta Crystallographica Section D: Biological Crystallography
, vol.58
, Issue.11
, pp. 1948-1954
-
-
Adams, P.D.1
Grosse-Kunstleve, R.W.2
Hung, L.-W.3
Ioerger, T.R.4
McCoy, A.J.5
Moriarty, N.W.6
Read, R.J.7
Sacchettini, J.C.8
Sauter, N.K.9
Terwilliger, T.C.10
-
40
-
-
74549194551
-
Molecular replacement with MOLREP
-
Vagin, A. & Teplyakov, A. Molecular replacement with MOLREP. Acta Crystallogr. D 66, 22-25 (2010).
-
(2010)
Acta Crystallogr. D
, vol.66
, pp. 22-25
-
-
Vagin, A.1
Teplyakov, A.2
-
41
-
-
0028103275
-
The CCP4 suite: Programs for protein crystallography
-
Bailey, S. The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D 50, 760-763 (1994).
-
(1994)
Acta Crystallogr. D
, vol.50
, pp. 760-763
-
-
Bailey, S.1
-
42
-
-
77950798648
-
Recent developments in classical density modification
-
Cowtan, K. Recent developments in classical density modification. Acta Crystallogr. D 66, 470-478 (2010).
-
(2010)
Acta Crystallogr. D
, vol.66
, pp. 470-478
-
-
Cowtan, K.1
-
44
-
-
34547592557
-
MolProbity: All-atomcontacts and structure validation for proteins and nucleic acids
-
Davis, I. W. et al. MolProbity: all-atomcontacts and structure validation for proteins and nucleic acids. Nucleic Acids Res. 35, W375-W383 (2007).
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Davis, I.W.1
-
45
-
-
0037031906
-
Global conformational earrangements in integrin extracellular domains in outside-in and inside-out signaling
-
DOI 10.1016/S0092-8674(02)00935-2
-
Takagi, J., Petre, B. M., Walz, T. & Springer, T. A. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell 110, 599-611 (2002). (Pubitemid 35247840)
-
(2002)
Cell
, vol.110
, Issue.5
, pp. 599-611
-
-
Takagi, J.1
Petre, B.M.2
Walz, T.3
Springer, T.A.4
-
46
-
-
77957034686
-
Requirement of open headpiece conformation for activation of leukocyte integrin aXb2
-
Chen, X. et al. Requirement of open headpiece conformation for activation of leukocyte integrin aXb2. Proc. Natl Acad. Sci. USA 107, 14727-14732 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 14727-14732
-
-
Chen, X.1
|