Myotubes differentiate optimally on substrates with tissue-like stiffness: Pathological implications for soft or stiff microenvironments

Journal of Cell Biology

Volumn 166, Issue 6, 2004, Pages 877-887

  Engler, Adam J ^a   Griffin, Maureen A ^a   Sen, Shamik ^a   Bönnemann, Carsten G ^b   Sweeney, H Lee ^b,c   Discher, Dennis E ^a,b,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Adhesion; Differentiation; Muscular dystrophy; Myofibrillogenesis; Patterning

Indexed keywords

ACTIN; MYOSIN; VINCULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL CULTURE; CONTROLLED STUDY; FIBROBLAST; MICROENVIRONMENT; MUSCULAR DYSTROPHY; MYOBLAST; MYOTUBE; NONHUMAN; PATHOLOGY; PRIORITY JOURNAL; SARCOMERE; SKELETAL MUSCLE; STRESS FIBER;

ACRYLIC RESINS; ANIMALS; CELL ADHESION; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; ELASTICITY; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; GELS; MICE; MICE, INBRED C3H; MICE, MUTANT STRAINS; MICROSCOPY, ATOMIC FORCE; MODELS, BIOLOGICAL; MUSCLE FIBERS; MUSCLE, SKELETAL; SUBSTRATE SPECIFICITY;

ANIMALIA;

EID: 4544264684     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200405004     Document Type: Article

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