TRPV1 involvement in inflammatory tissue fibrosis in mice

American Journal of Pathology

Volumn 178, Issue 6, 2011, Pages 2654-2664

  Okada, Yuka ^a   Reinach, Peter S ^b   Shirai, Kumi ^a   Kitano, Ai ^a   Kao, Winston W Y ^c   Flanders, Kathleen C ^d   Miyajima, Masayasu ^a   Liu, Hongshan ^c   Zhang, Jianhua ^c   Saika, Shizuya ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 CHLORO N (3 METHOXYPHENYL)CINNAMAMIDE; ALKALI; JYL 1421; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW TRANSPLANTATION; CELL INVASION; CONTROLLED STUDY; CORNEA; FIBROSIS; GENE EXPRESSION; GENOTYPE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KNOCKOUT MOUSE; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SCAR FORMATION; TISSUE INJURY;

EID: 79959385513     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.02.043     Document Type: Article

References (45)

1. Brodovsky SC, McCarty CA, Snibson G, Loughan M, Sullivan L, Daniell M, Taylar HR: Management of alkali burns: an 11-year retrospective review. Ophthalmology 2000, 107:1829-1835
2. Ishizaki M, Zhu G, Hasebe T, Shafer SS, Kao WW-Y: Expression of collagen I, smooth muscle a-actin, and vimentin during the healing of alkali-burned and lacerated corneas. Invest Ophthalmol Vis Sci 1993, 34:3320-3328 (Pubitemid 23346664)
3. Saika S, Kobata S, Hashizume N, Okada Y, Yamanaka O: Epithelial basement membrane in alkali-burned corneas in rats. Immunohistochemical study. Cornea 1993, 12:383-390 (Pubitemid 23249318)
4. Saika S, Uenoyama K, Hiroi K, Tanioka H, Takase K, Hikita M: Ascorbic acid phosphate ester and wound healing in rabbit corneal alkali burns: epithelial basement membrane and stroma. Graefes Arch Clin Exp Ophthalmol 1993, 231:221-227 (Pubitemid 23152846)
5. Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA: Myofibroblasts and mechano-regulation of connective tissue remodeling. Nat Rev Mol Cell Biol 2008, 3:349-363
6. Sridhar MS, Bansal AK, Sangwan VS, Rao GN: Amniotic membrane transplantation in acute chemical and thermal injury. Am J Ophthalmol 2000, 130:124-137
7. Meller D, Pires RT, Mack RJ, Figueiredo F, Heiligenhaus, Park WC, Prabhasawat P, John T, McLeod SD, Steuhl KP, Tseng SC: Amniotic membrane transplantation for acute chemical or thermal burns. Ophthalmology 2000, 107:980-989
8. Pedersen SF, Owsianik G, Nilius B: TRP channels: an overview. Cell Calcium 2005, 38:233-252 (Pubitemid 41283262)
9. Ramsey IS, Delling M, Clapham DE: An introduction to TRP channels. Annu Rev Physiol 2006, 68:619-647
10. Owsianik G, Talavera K, Voets T, Nilius B: Permeation and selectivity of TRP channels. Annu Rev Physiol 2006, 68:685-717
11. Montell C, Birnbaumer L, Flockerzi V: The TRP channels, a remarkably functional family. Cell 2002, 108:595-598 (Pubitemid 34241421)
12. Ciura S, Bourque CW: Transient receptor potential vanilloid 1 is required for intrinsic osmoreception in organum vasculosum lamina terminalis neurons and for normal thirst responses to systemic hyperosmolality. J Neurosci 2006, 26:9069-9075 (Pubitemid 44319398)
13. Steen KH, Reeh PW, Anton F, Handwerker HO: Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro. J Neurosci 1992, 12:86-95
14. García-Hirschfeld J, López-Briones LG, Belmonte C, Valdeolmillos M: Intracellular free calcium responses to protons and capsaicin in cultured trigeminal neurons. Neuroscience 1995, 67:235-43
15. Caterina MJ, Schumacher M, Tominaga M, Rosen TA, Levine JD, Julius D: The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997, 389:816-824 (Pubitemid 27462969)
16. Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Petersen-Zeitz KR, Kolzenburg M, Basbaum AI, Julius D: Impaired nocioception and pain sensation in mice lacking the capsaicin receptor. Science 2000, 288:306-303
17. Davis JB, Gray J, Gunthorpe MJ, Hatcher JP, Davey PT, Overend P, Harries MH, Latcham J, Clapham C, Atkinson K, Hughes SA, Rance K, Grau E, Harper AJ, Pugh PL, Roger DC, Blingham S, Randall A, Sheardown SA: Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature 2000, 405:183-187 (Pubitemid 30313536)
18. Saika S, Miyamoto T, Yamanaka O, Kato T, Ohnishi Y, Flanders KC, Ikeda K, Nakajima Y, Kao WW-Y, Sato M, Muragaki Y, Ooshima A: Therapeutic effect of topical administration of SN50, an inhibitor of nuclear factor-B, in treatment of corneal alkali burns in mice. Am J Pathol 2005, 166:1393-1403 (Pubitemid 40586510)
19. Saika S, Ikeda K, Yamanaka O, Flanders KC, Okada Y, Miyamoto T, Kitano A, Ooshima A, Nakajima Y, Ohnishi Y, Kao WW: Loss of tumor necrosis factor a potentiates transforming growth factor b-mediated pathogenic tissue response during wound healing. Am J Pathol 2006, 168:1848-1860 (Pubitemid 43825305)
20. Varga A, Németh J, Szabhó A, McDougall JJ, Zhang C, Elekes K, Pintér E, Szolcśnyi J, Helyes Z: Effects of the novel TRPV1 receptor antagonist SB366791 in vitro and in vivo in rat. Neurosci Lett 2005, 385:137-142 (Pubitemid 40961650)
21. Jakab B, Helyes Z, Varga A, Bölcskei K, Szabó A, Śndor K, Elekes K, Börzsei R, Keszthelyi D, Pintér E, Petho G, Németh J, Szolcśnyi J: Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat. Eur J Pharmacol 2005, 517:35-44 (Pubitemid 40910250)
22. Flanders KC, Ludecke G, Engels S, Cissel DS, Roberts AB, Kondaiah P, Lafyatis R, Sporn MB, Unsicker K: Localization and actions of transforming growth factor-bs in the embryonic nervous system. Development 1991, 113:183-191
23. Saika S, Ikeda K, Yamanaka O, Flanders KC, Ohnishi Y, Nakajima Y, Muragaki Y, Ooshima A: Adenoviral gene transfer of BMP-7. Id2 or Id3 suppresses injury-induced epithelial-mesenchymal transition of lens epithelium in mice. Am J Physiol Cell Physiol 2006, 290:C282-C289
24. Saika S, Yamanaka O, Okada Y, Tanaka S, Miyamoto T, Sumioka T, Kitano A, Shirai K, Ikeda K: TGF beta in fibroproliferative diseases in the eye. Front Biosci (Schol Ed) 2009, 1:376-90
25. Saika S, Ikeda K, Yamanaka O, Miyamoto T, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Nakajima Y, Kao WW, Flanders KC, Roberts AB: Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali. Am J Pathol 2005, 166:1405-1418 (Pubitemid 40586511)
26. Lukacs NW, Chensue SW, Smith RE, Strieter RM, Warmington K, Wilke C, Kunkel SL. Production of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 alpha by inflammatory granuloma fibroblasts. Am J Pathol 1994, 44:711-718 (Pubitemid 24172060)
27. Helme RD, Andrews PV, Watson BA: Neurogenic inflammation caused by wool fabric in the rat; possible mediation by substance P. Neurosci Lett 1986, 66:333-337 (Pubitemid 16038520)
28. Sehgal PB. Interleukin-6: molecular pathophysiology. J Invest Dermatol 1990, 94:2S-6S. (Pubitemid 20213060)
29. Serini G, Bochaton-Piallat ML, Ropraz P, Geinoz A, Borsi L, Zardi L, Gabbiani G: The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta 1. J Cell Biol 1998, 142:873-881 (Pubitemid 28381502)
30. Tomasek JJ, Gabbiani G, Hinz B, Chponnier C, Brown RA: Myofibroblasts and mechano-regulation of connective tissue remodeling. Nat Rev Mol Cell Biol 2002, 3:349-363 (Pubitemid 34619269)
31. Hester JV, Huang J, Petroll WM, Chavanagh HD: TGFβ induced myofibroblast differentiation of rabbit keratocytes requires synergistic TGFβ. PDGF and integrin signaling. Exp Eye Res 2002, 75:645-657 (Pubitemid 36034629)
32. Desmouliere, A, Darby IA, Gabbiani G: Normal and pathologic soft tissue remodeling: role of the myofibroblast, with special emphasis on liver and kidney fibrosis. Lab Invest 2003, 83:1689-1707 (Pubitemid 38018532)
33. Brodovsky SC, McCarty CA, Snibson G, et al: Management of alkali burns: an 11-year retrospective review. Ophthalmology 2000, 107: 1829-1835
34. Meller D, Pires RT, Mack RJ, Figueiredo F, Heiligenhaus A, Park WC, Prabhasawat P, John T, McLeod SD, Steuhl KP, Tseng SC: Amniotic membrane transplantation for acute chemical or thermal burns. Ophthalmology 2000, 107:980-989
35. Saika S, Yamanaka O, Sumioka T, Miyamoto T, Miyazaki K, Okada Y, Kitano A, Shirai K, Tanaka S, Ikeda K: Fibrotic disorders in the eye: targets of gene therapy. Prog Retin Eye Res 2008, 27:177-196
36. Azar DT. Corneal angiogenic privilege: angiogenic and antiangiogenic factors in corneal avascularity, vasculogenesis, and wound healing (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc 2006, 104:264-302 (Pubitemid 46495064)
37. Papathanassiou M, Theodossiadis PG, Liarakos VS, Rouvas A, Giamarellos-Bourboulis EJ, Vergados IA: Inhibition of corneal neovascularization by subconjunctival bevacizumab in an animal model. Am J Ophthalmol 2008, 145:424-431
38. Saika S: TGFb pathobiology in the eye. Lab Invest 2006, 86:106-115
39. Nassini R, De Siena G, DeCesaris F, Geppetti P: Transient receptor potential channels as novel drug targets in respiratory diseases. Curr Opin Investig Drugs 2010, 11:535-542
40. Szolcsanyi J: Hot target on nociceptors: perspectives, caveats and unique features. Br J Pharmacol 2008, 155:1142-1144
41. Helyes Z, Elekes K, Németh J, Pozsgai G, Śndor K, Kereskai L, Börzsei R, Pintér E, Szabó A, Szolcśnyi J: Role of transient receptor potential vanilloid 1 receptors in endotoxin-induced airway inflammation in the mouse. Am J Physiol Lung Cell Mol Physiol 2007, 292: L1173-L1181 (Pubitemid 47084861)
42. Keeble JE, Brain SD: Capsaicin-induced vasoconstriction in the mouse knee joint: a study using TRPV1 knockout mice. Neurosci Lett 2006, 401:55-58
43. Pan XQ, Gonzalez JA, Chang S, Chacko S, Wein AJ, Malykhina AP: Experimental colitis triggers the release of substance P and calcitonin gene-related peptide in the urinary bladder via TRPV1 signaling pathways. Exp Neurol 2010, 225:262-273
44. Szitter I, Pozsgai G, Sandor K, Elekes K, Kemeny A, Perkecz A, Szolcsanyi J, Helyes Z, Pinter E: The role of transient receptor potential vanilloid 1 (Trpv1) receptors in dextran sulfate-induced colitis in mice. J Mol Neurosci 2010, 42:80-88
45. Shieh KR, Yi CH, Liu TT, Tseng HL, Ho HC, Hsieh HT, Chen CL: Evidence for neurotrophic factors associating with TRPV1 gene expression in the inflamed human esophagus. Neurogastroenterol Motil 2010, 22:971-977