Increased PDGFRα Activation Disrupts Connective Tissue Development and Drives Systemic Fibrosis

Developmental Cell

Volumn 16, Issue 2, 2009, Pages 303-313

  Olson, Lorin E ^a,b   Soriano, Philippe ^a,b  

^a Fred Hutchinson Cancer Research Center   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

DEVBIO; SIGNALING

Indexed keywords

ARF PROTEIN; PHOSPHOTRANSFERASE; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR;

ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL HYPERPLASIA; CONNECTIVE TISSUE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; FIBROBLAST; FIBROSIS; GENE MUTATION; HOMEOSTASIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN DEPLETION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; STROMA; TISSUE GROWTH; TUMOR SUPPRESSOR GENE; ANIMAL; BIOLOGICAL MODEL; CELL PROLIFERATION; FEMALE; LUNG; METABOLISM; MUTATION; TRANSGENIC MOUSE;

MUS;

ANIMALS; CELL PROLIFERATION; CONNECTIVE TISSUE; FEMALE; FIBROBLASTS; FIBROSIS; HOMEOSTASIS; LUNG; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MUTATION; PHENOTYPE; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; SIGNAL TRANSDUCTION;

EID: 59649093844     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2008.12.003     Document Type: Article

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