Hyaluronan synthesis mediates the fibrotic response of keratocytes to transforming growth factor β

Journal of Biological Chemistry

Volumn 285, Issue 42, 2010, Pages 32012-32019

  Guo, Naxin ^a,b   Li, Xuan ^a   Mann, Mary M ^a   Funderburgh, Martha L ^a   Du, Yiqin ^a   Funderburgh, James L ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DIVISIONS; CELLULAR RESPONSE; COLLAGEN TYPE III; CONCENTRATION-DEPENDENT; EXTRACELLULAR; HYALURONAN; HYALURONAN SYNTHESIS; IN-VITRO; KERATOCYTES; SMOOTH MUSCLE ACTINS; SYNTHASES; TRANSFORMING GROWTH FACTORS; UP-REGULATION; WOUND HEALING;

CELL PROLIFERATION; MUSCLE;

GENE EXPRESSION;

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 3; FIBRONECTIN; HYALURONIC ACID; HYALURONIDASE; HYMECROMONE; LUCIFERASE; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CARBOHYDRATE SYNTHESIS; CELL DIVISION; CELL FUNCTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORNEA CELL; CYTOKINE RELEASE; DRUG MECHANISM; ENZYME INDUCTION; EXTRACELLULAR MATRIX; MYOFIBROBLAST; NONHUMAN; OCULAR FIBROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCAR FORMATION; SIGNAL TRANSDUCTION; UPREGULATION; WOUND HEALING;

ANIMALS; CATTLE; CELLS, CULTURED; CORNEA; FIBROSIS; GLUCURONOSYLTRANSFERASE; HUMANS; HYALURONIC ACID; HYALURONOGLUCOSAMINIDASE; ISOENZYMES; KERATINOCYTES; PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 77957787923     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.127183     Document Type: Article

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