TGFβ and PDGF-B signaling blockade inhibits myofibroblast development from both bone marrow-derived and keratocyte-derived precursor cells invivo

Experimental Eye Research

Volumn 121, Issue , 2014, Pages 35-40

  Singh, Vivek ^a,c   Jaini, Ritika ^a   Torricelli, André A M ^a   Santhiago, Marcony R ^a   Singh, Nirbhai ^b   Ambati, Bala K ^b   Wilson, Steven E ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c L V PRASAD EYE INSTITUTE   (India)

Author keywords

Bone marrow derived cells; Cornea; Haze; Immunocytochemistry; Keratocytes; Myofibroblasts; Opacity; Plateletderived growth factor; Stroma; Transforming growth factor beta

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; PLASMID VECTOR; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW TRANSPLANTATION; CELL MATURATION; CELL SELECTION; CONTROLLED STUDY; CORNEA CELL; ENDOPLASMIC RETICULUM; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; KERATECTOMY; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

BONE MARROW-DERIVED CELLS; CORNEA; HAZE; IMMUNOCYTOCHEMISTRY; KERATOCYTES; MYOFIBROBLASTS; OPACITY; PLATELETDERIVED GROWTH FACTOR; STROMA; TRANSFORMING GROWTH FACTOR BETA;

ACTINS; ANIMALS; BONE MARROW CELLS; CORNEAL KERATOCYTES; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; MICE; MICE, INBRED C57BL; MYOFIBROBLASTS; PHOTOREFRACTIVE KERATECTOMY; PLASMIDS; PROTO-ONCOGENE PROTEINS C-SIS; SIGNAL TRANSDUCTION; STEM CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84896026207     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2014.02.013     Document Type: Article

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