메뉴 건너뛰기




Volumn 24, Issue 19, 2005, Pages 3400-3410

Wound-healing defect of CD18-/- mice due to a decrease in TGF-β1 and myofibroblast differentiation

Author keywords

Cellular differentiation; Growth factors; Integrins; Myofibroblast; Wound healing

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD18 ANTIGEN; FIBRONECTIN; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

EID: 27144534924     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600809     Document Type: Article
Times cited : (134)

References (62)
  • 3
    • 0032853437 scopus 로고    scopus 로고
    • Trauma-hemorrhage delays wound healing potentially by increasing pro-inflammatory cytokines at the wound site
    • Angele MK, Knoferl MW, Ayala A, Albina JE, Cioffi WG, Bland KI, Chaudry IH (1999) Trauma-hemorrhage delays wound healing potentially by increasing pro-inflammatory cytokines at the wound site. Surgery 126: 279-285
    • (1999) Surgery , vol.126 , pp. 279-285
    • Angele, M.K.1    Knoferl, M.W.2    Ayala, A.3    Albina, J.E.4    Cioffi, W.G.5    Bland, K.I.6    Chaudry, I.H.7
  • 4
    • 0025255615 scopus 로고
    • Structure and function of the leukocyte adhesion molecules CD11/CD18
    • Arnaout MA (1990) Structure and function of the leukocyte adhesion molecules CD11/CD18. Blood 75: 1037-1050
    • (1990) Blood , vol.75 , pp. 1037-1050
    • Arnaout, M.A.1
  • 5
    • 0028086164 scopus 로고
    • Dependence of collagen remodelling on alpha-smooth muscle actin expression by fibroblasts
    • Arora PD, McCulloch CA (1994) Dependence of collagen remodelling on alpha-smooth muscle actin expression by fibroblasts. J Cell Physiol 159: 161-175
    • (1994) J Cell Physiol , vol.159 , pp. 161-175
    • Arora, P.D.1    McCulloch, C.A.2
  • 6
    • 0032938967 scopus 로고    scopus 로고
    • Mast cells and their mediators in cutaneous wound healing - Active participants or innocent bystanders?
    • Artuc M, Hermes B, Steckelings UM, Grutzkau A, Henz BM (1999) Mast cells and their mediators in cutaneous wound healing - active participants or innocent bystanders? Exp Dermatol 8: 1-16
    • (1999) Exp Dermatol , vol.8 , pp. 1-16
    • Artuc, M.1    Hermes, B.2    Steckelings, U.M.3    Grutzkau, A.4    Henz, B.M.5
  • 9
    • 0034878046 scopus 로고    scopus 로고
    • Expression of TGF-beta and its receptors in murine fetal and adult dermal wounds
    • Cowin AJ, Holmes TM, Brosnan P, Ferguson MW (2001) Expression of TGF-beta and its receptors in murine fetal and adult dermal wounds. Eur J Dermatol 11: 424-431
    • (2001) Eur J Dermatol , vol.11 , pp. 424-431
    • Cowin, A.J.1    Holmes, T.M.2    Brosnan, P.3    Ferguson, M.W.4
  • 10
    • 0033926275 scopus 로고    scopus 로고
    • Delayed wound healing in immunodeficient TGF-beta 1 knockout mice
    • Crowe MJ, Doetschman T, Greenhalgh DG (2000) Delayed wound healing in immunodeficient TGF-beta 1 knockout mice. J Invest Dermatol 115: 3-11
    • (2000) J Invest Dermatol , vol.115 , pp. 3-11
    • Crowe, M.J.1    Doetschman, T.2    Greenhalgh, D.G.3
  • 12
    • 0027212686 scopus 로고
    • Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
    • Desmoulière A, Geinoz A, Gabbiani F, Gabbiani G (1993) Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 122: 103-111
    • (1993) J Cell Biol , vol.122 , pp. 103-111
    • Desmoulière, A.1    Geinoz, A.2    Gabbiani, F.3    Gabbiani, G.4
  • 14
    • 0027392719 scopus 로고
    • Transforming growth factor-beta 1 enhances polymorphonuclear leucocyte accumulation in dermal inflammation and transendothelial migration by a priming action
    • Drake WT, Issekutz AC (1993) Transforming growth factor-beta 1 enhances polymorphonuclear leucocyte accumulation in dermal inflammation and transendothelial migration by a priming action. Immunology 78: 197-204
    • (1993) Immunology , vol.78 , pp. 197-204
    • Drake, W.T.1    Issekutz, A.C.2
  • 15
    • 0023676777 scopus 로고
    • Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells
    • Dustin ML, Springer TA (1988) Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells. J Cell Biol 107: 321-331
    • (1988) J Cell Biol , vol.107 , pp. 321-331
    • Dustin, M.L.1    Springer, T.A.2
  • 16
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM (1998) Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 101: 890-898
    • (1998) J Clin Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 17
    • 0035846941 scopus 로고    scopus 로고
    • Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts
    • Fadok VA, de Cathelineau A, Daleke DL, Henson PM, Bratton DL (2001) Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts. J Biol Chem 276: 1071-1077
    • (2001) J Biol Chem , vol.276 , pp. 1071-1077
    • Fadok, V.A.1    De Cathelineau, A.2    Daleke, D.L.3    Henson, P.M.4    Bratton, D.L.5
  • 19
    • 0027292168 scopus 로고
    • Signaling properties of CR3 (CD11b/CD18) and CR1 (CD35) in relation to phagocytosis of complement-opsonized particles
    • Fallman M, Andersson R, Andersson T (1993) Signaling properties of CR3 (CD11b/CD18) and CR1 (CD35) in relation to phagocytosis of complement-opsonized particles. J Immunol 151: 330-338
    • (1993) J Immunol , vol.151 , pp. 330-338
    • Fallman, M.1    Andersson, R.2    Andersson, T.3
  • 20
    • 0025727898 scopus 로고
    • Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: Implications for TGF-beta-driven synovial inflammation and hyperplasia
    • Fava RA, Olsen NJ, Postlethwaite AE, Broadley KN, Davidson JM, Nanney LB, Lucas C, Townes AS (1991) Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: implications for TGF-beta-driven synovial inflammation and hyperplasia. J Exp Med 173: 1121-1132
    • (1991) J Exp Med , vol.173 , pp. 1121-1132
    • Fava, R.A.1    Olsen, N.J.2    Postlethwaite, A.E.3    Broadley, K.N.4    Davidson, J.M.5    Nanney, L.B.6    Lucas, C.7    Townes, A.S.8
  • 21
    • 0037033795 scopus 로고    scopus 로고
    • The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure
    • Feugate JE, Li Q, Wong L, Martins-Green M (2002) The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure. J Cell Biol 156: 161-172
    • (2002) J Cell Biol , vol.156 , pp. 161-172
    • Feugate, J.E.1    Li, Q.2    Wong, L.3    Martins-Green, M.4
  • 23
    • 0035159094 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin expression upregulates fibroblast contractile activity
    • Hinz B, Celetta G, Tomasek JJ, Gabbiani G, Chaponnier C (2001a) Alpha-smooth muscle actin expression upregulates fibroblast contractile activity. Mol Biol Cell 12: 2730-2741
    • (2001) Mol Biol Cell , vol.12 , pp. 2730-2741
    • Hinz, B.1    Celetta, G.2    Tomasek, J.J.3    Gabbiani, G.4    Chaponnier, C.5
  • 24
    • 0037632844 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts
    • Hinz B, Dugina V, Ballestrem C, Wehrle-Haller B, Chaponnier C (2003) Alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts. Mol Biol Cell 14: 2508-2519
    • (2003) Mol Biol Cell , vol.14 , pp. 2508-2519
    • Hinz, B.1    Dugina, V.2    Ballestrem, C.3    Wehrle-Haller, B.4    Chaponnier, C.5
  • 25
    • 0034856168 scopus 로고    scopus 로고
    • Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation
    • Hinz B, Mastrangelo D, Iselin CE, Chaponnier C, Gabbiani G (2001b) Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation. Am J Pathol 159: 1009-1020
    • (2001) Am J Pathol , vol.159 , pp. 1009-1020
    • Hinz, B.1    Mastrangelo, D.2    Iselin, C.E.3    Chaponnier, C.4    Gabbiani, G.5
  • 26
    • 0028942106 scopus 로고
    • Human neutrophils lose their surface Fc gamma RIII and acquire Annexin V binding sites during apoptosis in vitro
    • Homburg CH, de Haas M, von dem Borne AE, Verhoeven AJ, Reutelingsperger CP, Roos D (1995) Human neutrophils lose their surface Fc gamma RIII and acquire Annexin V binding sites during apoptosis in vitro. Blood 85: 532-540
    • (1995) Blood , vol.85 , pp. 532-540
    • Homburg, C.H.1    De Haas, M.2    Von Dem Borne, A.E.3    Verhoeven, A.J.4    Reutelingsperger, C.P.5    Roos, D.6
  • 27
    • 0028966515 scopus 로고
    • CD11/CD18-independent transendothelial migration of human polymorphonuclear leukocytes and monocytes: Involvement of distinct and unique mechanisms
    • Issekutz AC, Chuluyan HE, Lopes N (1995) CD11/CD18-independent transendothelial migration of human polymorphonuclear leukocytes and monocytes: involvement of distinct and unique mechanisms. J Leukoc Biol 57: 553-561
    • (1995) J Leukoc Biol , vol.57 , pp. 553-561
    • Issekutz, A.C.1    Chuluyan, H.E.2    Lopes, N.3
  • 30
    • 0029872881 scopus 로고    scopus 로고
    • The dynamics of inflammatory cytokines in the healing process of mouse skin wound: A preliminary study for possible wound age determination
    • Kondo T, Ohshima T (1996) The dynamics of inflammatory cytokines in the healing process of mouse skin wound: a preliminary study for possible wound age determination. Int J Legal Med 108: 231-236
    • (1996) Int J Legal Med , vol.108 , pp. 231-236
    • Kondo, T.1    Ohshima, T.2
  • 31
    • 0030885763 scopus 로고    scopus 로고
    • Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins
    • Kuijpers TW, Van Lier RA, Hamann D, de Boer M, Thung LY, Weening RS, Verhoeven AJ, Roos D (1997) Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins. J Clin Invest 100: 1725-1733
    • (1997) J Clin Invest , vol.100 , pp. 1725-1733
    • Kuijpers, T.W.1    Van Lier, R.A.2    Hamann, D.3    De Boer, M.4    Thung, L.Y.5    Weening, R.S.6    Verhoeven, A.J.7    Roos, D.8
  • 33
    • 0035036832 scopus 로고    scopus 로고
    • The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter
    • Luhn K, Wild MK, Eckhardt M, Gerardy-Schahn R, Vestweber D (2001) The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter. Nat Genet 28: 69-72
    • (2001) Nat Genet , vol.28 , pp. 69-72
    • Luhn, K.1    Wild, M.K.2    Eckhardt, M.3    Gerardy-Schahn, R.4    Vestweber, D.5
  • 35
    • 0030934532 scopus 로고    scopus 로고
    • Wound healing - Aiming for perfect skin regeneration
    • Martin P (1997) Wound healing - aiming for perfect skin regeneration. Science 276: 75-81
    • (1997) Science , vol.276 , pp. 75-81
    • Martin, P.1
  • 36
    • 0033485401 scopus 로고    scopus 로고
    • Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells
    • McDonald PP, Fadok VA, Bratton D, Henson PM (1999) Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells. J Immunol 163: 6164-6172
    • (1999) J Immunol , vol.163 , pp. 6164-6172
    • McDonald, P.P.1    Fadok, V.A.2    Bratton, D.3    Henson, P.M.4
  • 37
    • 0032416392 scopus 로고    scopus 로고
    • Complement-dependent clearance of apoptotic cells by human macrophages
    • Mevorach D, Mascarenhas JO, Gershov D, Elkon KB (1998) Complement-dependent clearance of apoptotic cells by human macrophages. J Exp Med 188: 2313-2320
    • (1998) J Exp Med , vol.188 , pp. 2313-2320
    • Mevorach, D.1    Mascarenhas, J.O.2    Gershov, D.3    Elkon, K.B.4
  • 39
    • 0024043131 scopus 로고
    • Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: Implications for wound healing
    • Montesano R, Orci L (1988) Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing. Proc Natl Acad Sci USA 85: 4894-4897
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4894-4897
    • Montesano, R.1    Orci, L.2
  • 40
    • 1642285950 scopus 로고    scopus 로고
    • Impairment of skin wound healing in beta-1, 4-galactosyltransferase- deficient mice with reduced leukocyte recruitment
    • Mori R, Kondo T, Nishie T, Ohshima T, Asano M (2004) Impairment of skin wound healing in beta-1, 4-galactosyltransferase-deficient mice with reduced leukocyte recruitment. Am J Pathol 164: 1303-1314
    • (2004) Am J Pathol , vol.164 , pp. 1303-1314
    • Mori, R.1    Kondo, T.2    Nishie, T.3    Ohshima, T.4    Asano, M.5
  • 42
    • 0035313060 scopus 로고    scopus 로고
    • Nonphlogistic clearance of late apoptotic neutrophils by macrophages: Efficient phagocytosis independent of beta 2 integrins
    • Ren Y, Stuart L, Lindberg FP, Rosenkranz AR, Chen Y, Mayadas TN, Savill J (2001) Nonphlogistic clearance of late apoptotic neutrophils by macrophages: efficient phagocytosis independent of beta 2 integrins. J Immunol 166: 4743-4750
    • (2001) J Immunol , vol.166 , pp. 4743-4750
    • Ren, Y.1    Stuart, L.2    Lindberg, F.P.3    Rosenkranz, A.R.4    Chen, Y.5    Mayadas, T.N.6    Savill, J.7
  • 45
    • 0031828004 scopus 로고    scopus 로고
    • The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1
    • Serini G, Bochaton-Piallat ML, Ropraz P, Geinoz A, Borsi L, Zardi L, Gabbiani G (1998) The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1. J Cell Biol 142: 873-881
    • (1998) J Cell Biol , vol.142 , pp. 873-881
    • Serini, G.1    Bochaton-Piallat, M.L.2    Ropraz, P.3    Geinoz, A.4    Borsi, L.5    Zardi, L.6    Gabbiani, G.7
  • 46
    • 0033178473 scopus 로고    scopus 로고
    • Mechanisms of myofibroblast activity and phenotypic modulation
    • Serini G, Gabbiani G (1999) Mechanisms of myofibroblast activity and phenotypic modulation. Exp Cell Res 250: 273-283
    • (1999) Exp Cell Res , vol.250 , pp. 273-283
    • Serini, G.1    Gabbiani, G.2
  • 47
    • 0015383163 scopus 로고
    • The neutrophilic leukocyte in wound repair a study with anti-neutrophil serum
    • Simpson DM, Ross R (1972) The neutrophilic leukocyte in wound repair a study with anti-neutrophil serum. J Clin Invest 51: 2009-2023
    • (1972) J Clin Invest , vol.51 , pp. 2009-2023
    • Simpson, D.M.1    Ross, R.2
  • 48
    • 0033517356 scopus 로고    scopus 로고
    • Cutaneous wound healing
    • Singer AJ, Clark RA (1999) Cutaneous wound healing. N Engl J Med 341: 738-746
    • (1999) N Engl J Med , vol.341 , pp. 738-746
    • Singer, A.J.1    Clark, R.A.2
  • 49
    • 0035375048 scopus 로고    scopus 로고
    • Cell adhesion and migration properties of beta 2-integrin negative polymorphonuclear granulocytes on defined extracellular matrix molecules. Relevance for leukocyte extravasation
    • Sixt M, Hallmann R, Wendler O, Scharffetter-Kochanek K, Sorokin LM (2001) Cell adhesion and migration properties of beta 2-integrin negative polymorphonuclear granulocytes on defined extracellular matrix molecules. Relevance for leukocyte extravasation. J Biol Chem 276: 18878-18887
    • (2001) J Biol Chem , vol.276 , pp. 18878-18887
    • Sixt, M.1    Hallmann, R.2    Wendler, O.3    Scharffetter-Kochanek, K.4    Sorokin, L.M.5
  • 50
    • 0022881517 scopus 로고
    • A monoclonal antibody against alpha-smooth muscle actin: A new probe for smooth muscle differentiation
    • Skalli O, Ropraz P, Trzeciak A, Benzonana G, Gillessen D, Gabbiani G (1986) A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol 103: 2787-2796
    • (1986) J Cell Biol , vol.103 , pp. 2787-2796
    • Skalli, O.1    Ropraz, P.2    Trzeciak, A.3    Benzonana, G.4    Gillessen, D.5    Gabbiani, G.6
  • 51
    • 0022438545 scopus 로고
    • The importance of the Mac-1, LFA-1 glycoprotein family in monocyte and granulocyte adherence, chemotaxis, and migration into inflammatory sites: Insights from an experiment of nature
    • Springer TA, Anderson DC (1986) The importance of the Mac-1, LFA-1 glycoprotein family in monocyte and granulocyte adherence, chemotaxis, and migration into inflammatory sites: insights from an experiment of nature. Ciba Found Symp 118: 102-126
    • (1986) Ciba Found Symp , vol.118 , pp. 102-126
    • Springer, T.A.1    Anderson, D.C.2
  • 52
    • 0024592732 scopus 로고
    • Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1
    • Staunton DE, Dustin ML, Springer TA (1989) Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1. Nature 339: 61-64
    • (1989) Nature , vol.339 , pp. 61-64
    • Staunton, D.E.1    Dustin, M.L.2    Springer, T.A.3
  • 54
    • 0027431908 scopus 로고
    • Resistance of mice to experimental leishmaniasis is associated with more rapid appearance of mature macrophages in vitro and in vivo
    • Sunderkötter C, Kunz M, Steinbrink K, Meinardus-Hager G, Goebeler M, Bildau H, Sorg C (1993) Resistance of mice to experimental leishmaniasis is associated with more rapid appearance of mature macrophages in vitro and in vivo. J Immunol 151: 4891-4901
    • (1993) J Immunol , vol.151 , pp. 4891-4901
    • Sunderkötter, C.1    Kunz, M.2    Steinbrink, K.3    Meinardus-Hager, G.4    Goebeler, M.5    Bildau, H.6    Sorg, C.7
  • 60
    • 0032873467 scopus 로고    scopus 로고
    • A role for beta(2) integrins (CD11/CD18) in the regulation of cytokine gene expression of polymorphonuclear neutrophils during the inflammatory response
    • Walzog B, Weinmann P, Jeblonski F, Scharffetter-Kochanek K, Bommert K, Gaehtgens P (1999b) A role for beta(2) integrins (CD11/CD18) in the regulation of cytokine gene expression of polymorphonuclear neutrophils during the inflammatory response. FASEB J 13: 1855-1865
    • (1999) FASEB J , vol.13 , pp. 1855-1865
    • Walzog, B.1    Weinmann, P.2    Jeblonski, F.3    Scharffetter-Kochanek, K.4    Bommert, K.5    Gaehtgens, P.6
  • 61
    • 0037438678 scopus 로고    scopus 로고
    • A role for apoptosis in the control of neutrophil homeostasis in the circulation: Insights from CD18-deficient mice
    • Weinmann P, Scharffetter-Kochanek K, Forlow SB, Peters T, Walzog B (2003) A role for apoptosis in the control of neutrophil homeostasis in the circulation: insights from CD18-deficient mice. Blood 101: 739-746
    • (2003) Blood , vol.101 , pp. 739-746
    • Weinmann, P.1    Scharffetter-Kochanek, K.2    Forlow, S.B.3    Peters, T.4    Walzog, B.5
  • 62
    • 0038676258 scopus 로고    scopus 로고
    • Regulation of wound healing by growth factors and cytokines
    • Werner S, Grose R (2003) Regulation of wound healing by growth factors and cytokines. Physiol Rev 83: 835-870
    • (2003) Physiol Rev , vol.83 , pp. 835-870
    • Werner, S.1    Grose, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.