Inhibitory effects of PPARγ ligands on TGF-β1-induced corneal myofibroblast transformation

American Journal of Pathology

Volumn 184, Issue 5, 2014, Pages 1429-1445

  Jeon, Kye Im ^a   Kulkarni, Ajit ^a   Woeller, Collynn F ^b   Phipps, Richard P ^a,b   Sime, Patricia J ^a,b   Hindman, Holly B ^a,b   Huxlin, Krystel R ^a,b  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOSIN LIGHT CHAIN 2; PROTEIN KINASE B; ROSIGLITAZONE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMOOTH MUSCLE ACTIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA1; TROGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 9-DEOXY-DELTA-9-PROSTAGLANDIN D2; ACTIN; CHROMAN DERIVATIVE; LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN D2; PROTEIN KINASE INHIBITOR; SMAD PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL TRANSFORMATION; CONTROLLED STUDY; CORNEA CELL; CORNEA INJURY; CORNEAL FIBROBLAST; DRUG EFFICACY; DRUG SAFETY; HAZE; INTRACELLULAR SIGNALING; MYOFIBROBLAST; NONHUMAN; PHOTOREFRACTIVE KERATECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; WESTERN BLOTTING; WOUND HEALING; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CAT; CELL NUCLEUS; CORNEA; DRUG EFFECTS; ENZYMOLOGY; FIBROSIS; HUMAN; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSFORMED CELL LINE;

ACTINS; ANIMALS; CATS; CELL LINE, TRANSFORMED; CELL NUCLEUS; CHROMANS; COLLAGEN TYPE I; CORNEA; FIBRONECTINS; FIBROSIS; HUMANS; LIGANDS; MYOFIBROBLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PPAR GAMMA; PROSTAGLANDIN D2; PROTEIN KINASE INHIBITORS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SMAD PROTEINS; THIAZOLIDINEDIONES; TRANSFORMING GROWTH FACTOR BETA1; WOUND HEALING;

EID: 84899515436     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.01.026     Document Type: Article

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