Induction of α-smooth muscle actin expression and myofibroblast transformation in cultured corneal keratocytes

Cornea

Volumn 15, Issue 5, 1996, Pages 505-516

  Jester, James V ^a   Barry Lane, Patricia A ^a   Cavanagh, H Dwight ^a   Petroll, W Matthew ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Actin; 5 1 Integrin; Cornea; Fibroblasts; Myofibroblasts

Indexed keywords

ALPHA ACTIN; HEPARIN; INTEGRIN; TRANSFORMING GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY AFFINITY; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL TRANSFORMATION; CORNEA CELL; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RABBIT; RECEPTOR BINDING;

ACTINS; ANIMALS; BLOTTING, WESTERN; CELL DIVISION; CELLS, CULTURED; CORNEA; FIBROBLAST GROWTH FACTOR 2; FIBROBLASTS; FIBRONECTINS; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HEPARIN; MUSCLE, SMOOTH; PRECIPITIN TESTS; RABBITS; RECEPTORS, FIBRONECTIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0029743832     PISSN: 02773740     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Hay ED, Revel JP. Fine structure of the developing avian cornea. In: Wolsky A, Tarrytown NY, Chen PS, eds. Monographs in developmental biology. Basel, Switzerland: S. Karger, 1969:47-52.
2. Jester JV, Rodrigues MM, Herman IM. Characterization of avascular corneal wound healing fibroblasts: new insights into the myofibroblast. Am J Pathol 1987;127:140-8.
3. Luttrull J, Smith R, Jester JV. In vitro contractility of avascular corneal wounds in rabbit eyes. Invest Ophthalmol Vis Sci 1985;26:1449-52.
4. Garana RMR, Petroll WM, Chen WT, et al. Radial keratotomy II: role of the myofibroblast in corneal wound contraction. Invest Ophthalmol Vis Sci 1992;33:3271-82.
5. Jester JV, Petroll WM, Barry PA, Cavanagh HD. Expression of α-actin during corneal stromal wound healing. Invest Ophthalmol Vis Sci 1995;36:809-19.
6. Nishida T, Yasumoto K, Otori T, Desaki J. The network structure of corneal fibroblasts in the rat as revealed by scanning electron microscopy. Invest Ophthalmol Vis Sci 1988;29:1887-90.
7. Jester JV, Barry P, Lind G, Petroll WM, Garana R, Cavanagh HD. Corneal keratocytes: in situ and in vitro organization of cytoskeletal contractile proteins. Invest Ophthalmol Vis Sci 1994;35:730-43.
8. Masur SK, Cheung JKH, Antohi S. Identification of integrins in cultured corneal fibroblasts and in isolated keratocytes. Invest Ophthalmol Vis Sci 1993;34:2690-8.
9. Masur SK, Connors RL, Antohi S, Weinstein E, Cheung JKH. Antibody to β1 integrins selects myofibroblasts from cultured corneal fibroblasts. Mol Biol Cell 1993;4:23a.
10. Desmouliere A, Rubbia-Brandt L, Abdiu A, Walz T, Macieira-Coelho A, Gabbiani G. α-Smooth muscle actin is expressed in a subpopulation of cultured and cloned fibroblasts and is modulated by γ-interferon. Exp Cell Res 1992;201:64-73.
11. Desmouliere A, Rubbia-Brandt L, Grau G, Gabbiani G. Heparin induces α-smooth muscle actin expression in cultured fibroblasts and in granulation tissue myofibroblasts. Lab Invest 1992;67:716-25.
12. Desmouliere A, Geinoz A, Gabbiani F, Gabbiani G. Transforming growth factor-β1 induces α-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 1993;122: 103-11.
13. Arciniegas E, Sutton AB, Allen TD, Shor AM. Transforming growth factor beta 1 promotes the differentiation of endothelial cells into smooth muscle-like cells in vitro. J Cell Sci 1992;103:521-9.
14. Ronnov-Jessen L, Petersen OW. Induction of α-smooth muscle actin by transforming growth factor-β1 in quiescent human breast gland fibroblasts. Lab Invest 1993;68:696-707.
15. Verbeek MM, Otte-Holler I, Wesseling P, Ruiter DJ, de Waal RMW. Induction of α-smooth muscle actin expression in cultured human brain pericytes by transforming growth factor-β1. Am J Pathol 1994;144:372-82.
16. β1 induces lens cells to accumulate α-smooth muscle actin, a marker for subcapsular cataracts. Curr Eye Res 1994;13:885-90.
17. Werb Z, Tremble PM, Behrendsten O, Crowley E, Damsky CH. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J Cell Biol 1989;109:877-89.
18. Fukamizu H, Grinnell F. Spatial organization of extracellular matrix and fibroblast activity: effect of serum, transforming growth factor β, and fibronectin. Exp Cell Res 1990;190: 276-82.
19. Darby I, Skalli O, Gabbiani G. α-Smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing. Lab Invest 1990;63:21-9.
20. β1) stimulate fibronectin synthesis and the transdifferentiation of fat-storing cells in the rat liver into myofibroblasts. Virchows Arch B Cell Pathol 1993;63:123-30.
21. Ohji M, SundarRaj N, Thoft RA. Transforming growth factor-β stimulates collagen and fibronectin synthesis by human corneal stromal fibroblasts in vitro. Curr Eye Res 1993;12: 703-9.
22. Romberger DJ, Beckmann JD, Claasen L, Ertl RF, Rennard SI. Modulation of fibronectin production of bovine bronchial epithelial cell by transforming growth factor-β. Am J Respir Cell Mol Biol 1992;7:149-55.
23. Roberts CJ, Birkenmeier TM, McQuillan JJ, et al. Transforming growth factor-β stimulates the expression of fibronectin and of both subunits of the human fibronectin receptor by cultured human lung fibroblasts. J Biol Chem 1988;263:4586-92.
24. Enenstein J, Waleh NS, Kramer RH. Basic FGF and TGF-β differentially modulate integrin expression of human microvascular endothelial cells. Exp Cell Res 1992;203:499-503.
25. Heino J, Ignotz RA, Hemler ME, Crouse C, Massague J. Regulation of cell adhesion receptors by transforming growth factor-β. J Biol Chem 1989;264:380-8.
26. Hongo M, Itoi M, Yamaguchi N, Imanishi J. Distribution of epidermal growth fator (EGF) receptors in rabbit corneal epithelial cells, keratocytes and endothelial cells, and the changes induced by transforming growth factor-β1. Exp Eye
27. Kurosada D, Kato K, Nagamoto Y, Negishi K. Growth factors influence contractility and alpha-smooth muscle actin expression in bovine lens epithelial cells. Invest Ophthalmol Vis Sci 1995;36:1701-8.
28. Pierce GF, Tarpley JE, Yanagihara D, Mustoe TA, Fox GM, Thomason A. Platelet-derived growth factor (BB homodimer), transforming growth factor-β1, and basic fibroblast growth factor in dermal wound healing. Am J Pathol 1992;140:1375-88.
29. Clark RAF. Regulation of fibroplasia in cutaneous wound repair. Am J Med Sci 1993;306:42-8. Res 1992;54:9-16.
30. Clark RAF. Regulation of fibroplasia in cutaneous wound repair. Am J Med Sci 1993;306:42-8. Res 1992;54:9-16.
31. Wilson SE, He Y-G, Lloyd SA. EGF, EGF receptor, basic FGF, TGF beta-1, and IL-1 alpha mRNA in human corneal epithelial cells and stromal fibroblasts. Invest Ophthalmol Vis Sci 1992;33:1756-65.
32. Nishida K, Sotozono C, Adachi W, Yamamoto S, Yokoi N, Kinoshita S. Transforming growth factor-β1, β2 and β3 mRNA expression in human cornea. Curr Eye Res 1994;14: 235-41.
33. Wilson SE, Schultz GS, Chegini N, Weng J, He Y-G. Epidermal growth factor, transforming growth factor alpha, transforming growth factor beta, acidic fibroblast growth factor, basic fibroblast growth factor, and interleukin-1 proteins in the cornea. Exp Eye Res 1994;59:63-72.
34. Nishida K, Kinoshita S, Yokoi N, Kaneda M, Hashimoto K, Yamamoto S. Immunohistochemical localization of transforming growth factor-β1, β2 and β3 latency-associated peptide in human cornea. Invest Ophthalmol Vis Sci 1994;35: 3289-94.
35. Grant MB, Khaw PT, Schultz GW, Adams JL, Shimizu RW. Effects of epidermal growth factor, fibroblast growth factor, and transforming growth factor-β on corneal cell chemotaxis. Invest Ophthalmol Vis Sci 1992;33:3292-301.
36. Fini ME, Girard MT, Matsubara M, Bartlett JD. Unique regulation of the matrix metalloproteinase, gelatinase B. Invest Ophthalmol Vis Sci 1995;36:622-33.
37. Girard MT, Matsubara M, Fini ME. Transforming growth factor-β and interleukin-1 modulate metalloproteinase expression by corneal stromal cells. Invest Ophthalmol Vis Sci 1991;31:2441-54.