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Volumn 4 E, Issue 1, 2012, Pages 426-452

New strategies in cancer chemoprevention by phytochemicals

Author keywords

Anti carcinogenic; Cancer; Chemoprevention; Phytochemicals; Review

Indexed keywords

3 INDOLEMETHANOL; ALLYL SULFIDE; BROMELAIN; CAPSAICIN; CURCUMIN; EPIGALLOCATECHIN GALLATE; GENISTEIN; LIMONENE; LUPEOL; LYCOPENE; PLANT MEDICINAL PRODUCT; RESVERATROL; TURMERIC; ANTINEOPLASTIC AGENT;

EID: 84860847973     PISSN: 19450494     EISSN: 19450508     Source Type: Journal    
DOI: 10.2741/389     Document Type: Article
Times cited : (19)

References (324)
  • 1
    • 0028305595 scopus 로고
    • Diet and health: What should we eat
    • WC Willett: Diet and health: what should we eat. Science 254, 532-537 (1994)
    • (1994) Science , vol.254 , pp. 532-537
    • Willett, W.C.1
  • 2
    • 0037177527 scopus 로고    scopus 로고
    • Balancing life-style and genomics research for disease prevention
    • WC Willett: Balancing life-style and genomics research for disease prevention. Science 296, 695-698 (2002)
    • (2002) Science , vol.296 , pp. 695-698
    • Willett, W.C.1
  • 3
    • 35348820076 scopus 로고    scopus 로고
    • A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancer
    • MA Gates, SS Tworoger, JL Hecht, I De Vivo, B Rosner, SE Hankinson: A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancer. Int J Cancer 121(10), 2225-2232 (2007)
    • (2007) Int J Cancer , vol.121 , Issue.10 , pp. 2225-2232
    • Gates, M.1    Tworoger, S.S.2    Hecht, J.L.3    De Vivo, I.4    Rosner, B.5    Hankinson, S.E.6
  • 4
    • 0003748910 scopus 로고
    • National Academy of Sciences, Committee on Diet and Health, National Research Council, National Academy Press Washington, DC
    • National Academy of Sciences, Committee on Diet and Health, National Research Council: Diet and Health: Implications for Reducing Chronic Disease Risk 1989, National Academy Press Washington, DC (1989)
    • (1989) Diet and Health: Implications for Reducing Chronic Disease Risk 1989
  • 5
    • 0003966001 scopus 로고
    • National Academy of Sciences, National Research Council, National Academy Press Washington, DC
    • National Academy of Sciences, National Research Council: Diet, Nutrition, and Cancer 1982, National Academy Press Washington, DC (1982)
    • (1982) Diet, Nutrition, and Cancer 1982
  • 6
    • 0043286304 scopus 로고    scopus 로고
    • Health benefits of fruits and vegetables are from additive and synergistic combination of phytochemicals
    • RH Liu: Health benefits of fruits and vegetables are from additive and synergistic combination of phytochemicals. Am J Clin Nutr 78, 517S-520S (2003)
    • (2003) Am J Clin Nutr , vol.78
    • Liu, R.H.1
  • 7
    • 0026701521 scopus 로고
    • Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence
    • G Block, B Patterson, A Subar: Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 18, 1-29 (1992)
    • (1992) Nutr Cancer , vol.18 , pp. 1-29
    • Block, G.1    Patterson, B.2    Subar, A.3
  • 10
    • 0033760576 scopus 로고    scopus 로고
    • Absorption and DNA protective effects of flavonoid glycosides from an onion meal
    • SP Boyle, VL Dobson, SJ Duthie, JAM Kyle, AR Collins: Absorption and DNA protective effects of flavonoid glycosides from an onion meal. Eur J Nutr 39, 213-223 (2000)
    • (2000) Eur J Nutr , vol.39 , pp. 213-223
    • Boyle, S.P.1    Dobson, V.L.2    Duthie, S.J.3    Kyle, J.4    Collins, A.R.5
  • 11
    • 0037021625 scopus 로고    scopus 로고
    • Antioxidant and antiproliferative activities of fruits
    • J Sun, Y-F Chu, X Wu, RH Liu: Antioxidant and antiproliferative activities of fruits. J Agric Food Chem 50, 7449-7454 (2002)
    • (2002) J Agric Food Chem , vol.50 , pp. 7449-7454
    • Sun, J.1    Chu, Y.-F.2    Wu, X.3    Liu, R.H.4
  • 12
    • 0037048727 scopus 로고    scopus 로고
    • Antioxidant activity of grains
    • KK Adom, RH Liu: Antioxidant activity of grains. J Agric Food Chem 50, 6182-6187 (2002)
    • (2002) J Agric Food Chem , vol.50 , pp. 6182-6187
    • Adom, K.K.1    Liu, R.H.2
  • 13
    • 0346849601 scopus 로고    scopus 로고
    • Phytochemicals and antioxidant activity of wheat varieties
    • KK Adom, ME Sorrells, RH Liu: Phytochemicals and antioxidant activity of wheat varieties. J Agric Food Chem 51, 7825-7834 (2003)
    • (2003) J Agric Food Chem , vol.51 , pp. 7825-7834
    • Adom, K.K.1    Sorrells, M.E.2    Liu, R.H.3
  • 15
    • 8444248818 scopus 로고    scopus 로고
    • Soy and isoflavone intake are associated with reduced risk of ovarian cancer in southeast china
    • M Zhang, X Xie, AH Lee, CW Binns: Soy and isoflavone intake are associated with reduced risk of ovarian cancer in southeast china. Nutr Cancer 49(2), 125-130 (2004)
    • (2004) Nutr Cancer , vol.49 , Issue.2 , pp. 125-130
    • Zhang, M.1    Xie, X.2    Lee, A.H.3    Binns, C.W.4
  • 16
    • 70449370068 scopus 로고    scopus 로고
    • Korean Meta-Analysis (KORMA) Study Group: Soy intake and risk of endocrine-related gynaecological cancer: A meta-analysis
    • SK Myung, W Ju, HJ Choi, SC Kim: Korean Meta-Analysis (KORMA) Study Group: Soy intake and risk of endocrine-related gynaecological cancer: a meta-analysis. BJOG 116(13), 1697-705 (2009)
    • (2009) BJOG , vol.116 , Issue.13 , pp. 1697-1705
    • Myung, S.K.1    Ju, W.2    Choi, H.J.3    Kim, S.C.4
  • 17
    • 31044452040 scopus 로고    scopus 로고
    • Effects of soy protein and soy phytochemicals on mammary tumor development in female transgenic mice over-expressing human pituitary growth hormone
    • J Hickey, A Bartke, T Winters, N Henry, W Banz: Effects of soy protein and soy phytochemicals on mammary tumor development in female transgenic mice over-expressing human pituitary growth hormone. J Med Food 8(4), 556-559 (2005)
    • (2005) J Med Food , vol.8 , Issue.4 , pp. 556-559
    • Hickey, J.1    Bartke, A.2    Winters, T.3    Henry, N.4    Banz, W.5
  • 18
    • 66149134904 scopus 로고    scopus 로고
    • Protective effects of Asian dietary items on cancers - Soy and ginseng
    • J Kim: Protective effects of Asian dietary items on cancers - soy and ginseng. Asian Pac J Cancer Prev 9(4), 543-558 (2008)
    • (2008) Asian Pac J Cancer Prev , vol.9 , Issue.4 , pp. 543-558
    • Kim, J.1
  • 19
    • 0033869533 scopus 로고    scopus 로고
    • Decreased ovarian hormones during a soya diet: Implications for breast cancer prevention
    • LJ Lu, KE Anderson, JJ Grady, F Kohen, M Nagamani: Decreased ovarian hormones during a soya diet: implications for breast cancer prevention. Cancer Res 60(15), 4112-4121(2000)
    • (2000) Cancer Res , vol.60 , Issue.15 , pp. 4112-4121
    • Lu, L.J.1    Anderson, K.E.2    Grady, J.J.3    Kohen, F.4    Nagamani, M.5
  • 20
    • 0011714009 scopus 로고    scopus 로고
    • Increased urinary excretion of 2-hydroxyestrone but not 16alpha-hydroxyestrone in premenopausal women during a soya diet containing isoflavones
    • LJ Lu, M Cree, S Josyula, M Nagamani, JJ Grady, KE Anderson: Increased urinary excretion of 2-hydroxyestrone but not 16alpha-hydroxyestrone in premenopausal women during a soya diet containing isoflavones. Cancer Res 60(5), 1299-1305 (2000)
    • (2000) Cancer Res , vol.60 , Issue.5 , pp. 1299-1305
    • Lu, L.J.1    Cree, M.2    Josyula, S.3    Nagamani, M.4    Grady, J.J.5    Anderson, K.E.6
  • 21
    • 0027179061 scopus 로고
    • Inhibition of tumor promoter induced hydrogen peroxide formation in vitro and in vivo by genistein
    • H Wei, L Wei, K Frenkel, R Bowen, S Barnes: Inhibition of tumor promoter induced hydrogen peroxide formation in vitro and in vivo by genistein. Nutr Cancer 20, 1-12 (1993)
    • (1993) Nutr Cancer , vol.20 , pp. 1-12
    • Wei, H.1    Wei, L.2    Frenkel, K.3    Bowen, R.4    Barnes, S.5
  • 22
    • 0038386061 scopus 로고    scopus 로고
    • Phytoestrogens and breast cancer
    • H Adlercreutz: Phytoestrogens and breast cancer. J Steroid Biochem Mol Biol 83(1-5), 113-118 (2002)
    • (2002) J Steroid Biochem Mol Biol , vol.83 , Issue.1-5 , pp. 113-118
    • Adlercreutz, H.1
  • 23
    • 50249177143 scopus 로고    scopus 로고
    • Genistein induces G2/M cell cycle arrest via stable activation of ERK1/2 pathway in MDA-MB-231 breast cancer cells
    • Z Li, J Li, B Mo, C Hu, H Liu, H Qi, X Wang, J Xu: Genistein induces G2/M cell cycle arrest via stable activation of ERK1/2 pathway in MDA-MB-231 breast cancer cells. Cell Biol Toxicol 24(5), 401-409 (2008)
    • (2008) Cell Biol Toxicol , vol.24 , Issue.5 , pp. 401-409
    • Li, Z.1    Li, J.2    Mo, B.3    Hu, C.4    Liu, H.5    Qi, H.6    Wang, X.7    Xu, J.8
  • 24
    • 0033971810 scopus 로고    scopus 로고
    • The potential of soybean foods as a chemoprevention approach for human urinary tract cancer
    • SJ Su, TM Yeh, HY Lei, NH Chow: The potential of soybean foods as a chemoprevention approach for human urinary tract cancer. Clin Cancer Res 6(1), 230-236 (2000)
    • (2000) Clin Cancer Res , vol.6 , Issue.1 , pp. 230-236
    • Su, S.J.1    Yeh, T.M.2    Lei, H.Y.3    Chow, N.H.4
  • 25
    • 0038308563 scopus 로고    scopus 로고
    • Effects of soy isoflavones on apoptosis induction and G2-M arrest in human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity
    • SJ Su, NH Chow, ML Kung, TC Hung, KL Chang: Effects of soy isoflavones on apoptosis induction and G2-M arrest in human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity. Nutr Cancer 45(1), 113-123 (2003)
    • (2003) Nutr Cancer , vol.45 , Issue.1 , pp. 113-123
    • Su, S.J.1    Chow, N.H.2    Kung, M.L.3    Hung, T.C.4    Chang, K.L.5
  • 27
    • 76749136204 scopus 로고    scopus 로고
    • Differential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cells
    • A Hsu, TM Bray, WG Helferich, DR Doerge, E Ho: Differential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cells. Exp Biol Med (Maywood) 235(1), 90-97 (2010)
    • (2010) Exp Biol Med (Maywood) , vol.235 , Issue.1 , pp. 90-97
    • Hsu, A.1    Bray, T.M.2    Helferich, W.G.3    Doerge, D.R.4    Ho, E.5
  • 28
    • 32944478433 scopus 로고    scopus 로고
    • Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis
    • AV Singh, AA Franke, GL Blackburn, JR Zhou: Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis. Cancer Res 66(3), 1851-1858 (2006)
    • (2006) Cancer Res , vol.66 , Issue.3 , pp. 1851-1858
    • Singh, A.V.1    Franke, A.A.2    Blackburn, G.L.3    Zhou, J.R.4
  • 29
    • 51749113325 scopus 로고    scopus 로고
    • Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway
    • Z Li, J Li, B Mo, C Hu, H Liu, H Qi, X Wang, J Xu: Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway. Toxicol In vitro 22(7), 1749-1753 (2008)
    • (2008) Toxicol in Vitro , vol.22 , Issue.7 , pp. 1749-1753
    • Li, Z.1    Li, J.2    Mo, B.3    Hu, C.4    Liu, H.5    Qi, H.6    Wang, X.7    Xu, J.8
  • 30
    • 4444331727 scopus 로고    scopus 로고
    • Cellular and physiological effects of soy flavonoids
    • T Valachovicova, V Slivova, D Sliva: Cellular and physiological effects of soy flavonoids. Mini Rev Med Chem 4(8), 881-887 (2004)
    • (2004) Mini Rev Med Chem , vol.4 , Issue.8 , pp. 881-887
    • Valachovicova, T.1    Slivova, V.2    Sliva, D.3
  • 31
    • 16644367866 scopus 로고    scopus 로고
    • Soy isoflavones suppress invasiveness of breast cancer cells by the inhibition of NF-kappaB/AP-1-dependent and -independent pathways
    • T Valachovicova, V Slivova, H Bergman, J Shuherk, D Sliva: Soy isoflavones suppress invasiveness of breast cancer cells by the inhibition of NF-kappaB/AP-1-dependent and -independent pathways. Int J Oncol 25(5), 1389-1395 (2004)
    • (2004) Int J Oncol , vol.25 , Issue.5 , pp. 1389-1395
    • Valachovicova, T.1    Slivova, V.2    Bergman, H.3    Shuherk, J.4    Sliva, D.5
  • 32
    • 77953608981 scopus 로고    scopus 로고
    • Long-term genistein treatment of MCF-7 cells decreases acetylated histone 3 expression and alters growth responses to mitogens and histone deacetylase inhibitors
    • Epub ahead of print
    • K Jawaid, SR Crane, JL Nowers, M Lacey, SA Whitehead: Long-term genistein treatment of MCF-7 cells decreases acetylated histone 3 expression and alters growth responses to mitogens and histone deacetylase inhibitors. J Steroid Biochem Mol Biol [Epub ahead of print] (2010)
    • J Steroid Biochem Mol Biol , vol.2010
    • Jawaid, K.1    Crane, S.R.2    Nowers, J.L.3    Lacey, M.4    Whitehead, S.A.5
  • 33
    • 0035527495 scopus 로고    scopus 로고
    • Isoflavones inhibit proliferation of ovarian cancer cells in vitro via an estrogen receptor-dependent pathway
    • X Chen, JJ Anderson: Isoflavones inhibit proliferation of ovarian cancer cells in vitro via an estrogen receptor-dependent pathway. Nutr Cancer 41(1-2), 165-171 (2001)
    • (2001) Nutr Cancer , vol.41 , Issue.1-2 , pp. 165-171
    • Chen, X.1    Anderson, J.J.2
  • 35
    • 77953229172 scopus 로고    scopus 로고
    • Daidzein effect on hormone refractory prostate cancer in vitro and in vivo compared to genistein and soy extract: Potentiation of radiotherapy
    • V Singh-Gupta, H Zhang, CK Yunker, Z Ahmad, D Zwier, FH Sarkar, GG Hillman: Daidzein effect on hormone refractory prostate cancer in vitro and in vivo compared to genistein and soy extract: potentiation of radiotherapy. Pharm Res 27(6), 1115-1127 (2010)
    • (2010) Pharm Res , vol.27 , Issue.6 , pp. 1115-1127
    • Singh-Gupta, V.1    Zhang, H.2    Yunker, C.K.3    Ahmad, Z.4    Zwier, D.5    Sarkar, F.H.6    Hillman, G.G.7
  • 37
    • 0037312591 scopus 로고    scopus 로고
    • Genistein and daidzein down-regulate prostate androgen-regulated transcript-1 (PART-1) gene expression induced by dihydrotestosterone in human prostate LNCaP cancer cells
    • L Yu, GL Blackburn, JR Zhou: Genistein and daidzein down-regulate prostate androgen-regulated transcript-1 (PART-1) gene expression induced by dihydrotestosterone in human prostate LNCaP cancer cells. J Nutr 133(2), 389-392 (2003)
    • (2003) J Nutr , vol.133 , Issue.2 , pp. 389-392
    • Yu, L.1    Blackburn, G.L.2    Zhou, J.R.3
  • 38
    • 0030507470 scopus 로고    scopus 로고
    • Inhibition of N-methyl-N-nitrosourea-induced mammary tumors in rats by the soybean isoflavones
    • AI Constantinou, RG Mehta, A Vaughan: Inhibition of N-methyl-N- nitrosourea-induced mammary tumors in rats by the soybean isoflavones. Anticancer Res 16(6A), 3293-3298 (1996)
    • (1996) Anticancer Res , vol.16 , Issue.6 A , pp. 3293-3298
    • Constantinou, A.I.1    Mehta, R.G.2    Vaughan, A.3
  • 39
    • 0029957108 scopus 로고    scopus 로고
    • Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats
    • WB Murrill, NM Brown, JX Zhang, PA Manzolillo, S Barnes, CA Lamartiniere: Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats. Carcinogenesis 17(7), 1451-1457 (1996)
    • (1996) Carcinogenesis , vol.17 , Issue.7 , pp. 1451-1457
    • Murrill, W.B.1    Brown, N.M.2    Zhang, J.X.3    Manzolillo, P.A.4    Barnes, S.5    Lamartiniere, C.A.6
  • 41
    • 69749125067 scopus 로고    scopus 로고
    • Antitumor and antiangiogenic activity of soy phytoestrogen on 7, 12-dimethylbenz [alpha] anthracene-induced mammary tumors following ovariectomy in Sprague-Dawley rats
    • X Kang, S Jin, Q Zhang: Antitumor and antiangiogenic activity of soy phytoestrogen on 7, 12-dimethylbenz [alpha] anthracene-induced mammary tumors following ovariectomy in Sprague-Dawley rats. J Food Sci 74(7), H237- H242 (2009)
    • (2009) J Food Sci , vol.74 , Issue.7
    • Kang, X.1    Jin, S.2    Zhang, Q.3
  • 42
    • 0032839509 scopus 로고    scopus 로고
    • Soybean phytochemicals inhibit the growth of transplantable human prostate carcinoma and tumor angiogenesis in mice
    • JR Zhou, ET Gugger, T Tanaka, Y Guo, GL Blackburn, SK Clinton: Soybean phytochemicals inhibit the growth of transplantable human prostate carcinoma and tumor angiogenesis in mice. J Nut 129(9), 1628-1635 (1999)
    • (1999) J Nut , vol.129 , Issue.9 , pp. 1628-1635
    • Zhou, J.R.1    Gugger, E.T.2    Tanaka, T.3    Guo, Y.4    Blackburn, G.L.5    Clinton, S.K.6
  • 43
    • 0036788365 scopus 로고    scopus 로고
    • Inhibition of orthotopic growth and metastasis of androgen-sensitive human prostate tumors in mice by bioactive soybean components
    • JR Zhou, L Yu, Y Zhong, RL Nassr, AA Franke, SM Gaston, GL Blackburn: Inhibition of orthotopic growth and metastasis of androgen-sensitive human prostate tumors in mice by bioactive soybean components. Prostate 53(2), 143-153 (2002)
    • (2002) Prostate , vol.53 , Issue.2 , pp. 143-153
    • Zhou, J.R.1    Yu, L.2    Zhong, Y.3    Nassr, R.L.4    Franke, A.A.5    Gaston, S.M.6    Blackburn, G.L.7
  • 44
    • 27744485649 scopus 로고    scopus 로고
    • Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells
    • A Tyagi, RP Singh, C Agarwal, S Siriwardana, RA Sclafani, R Agarwal: Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells. Carcinogenesis 26 (11): 1978-1987 (2005)
    • (2005) Carcinogenesis , vol.26 , Issue.11 , pp. 1978-1987
    • Tyagi, A.1    Singh, R.P.2    Agarwal, C.3    Siriwardana, S.4    Sclafani, R.A.5    Agarwal, R.6
  • 45
    • 0034902229 scopus 로고    scopus 로고
    • Resveratrol causes WAF-1/p21-mediated G(1)-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells
    • N Ahmad, VM Adhami, F Afaq, DK Feyes, H Mukhtar: Resveratrol causes WAF-1/p21-mediated G(1)-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells. Clin Cancer Res 7(5), 1466-1473 (2001)
    • (2001) Clin Cancer Res , vol.7 , Issue.5 , pp. 1466-1473
    • Ahmad, N.1    Adhami, V.M.2    Afaq, F.3    Feyes, D.K.4    Mukhtar, H.5
  • 46
    • 1842732153 scopus 로고    scopus 로고
    • Modulation of androgen receptor-dependent transcription by resveratrol and genistein in prostate cancer cells
    • S Gao, GZ Liu, Z Wang: Modulation of androgen receptor-dependent transcription by resveratrol and genistein in prostate cancer cells. Prostate 59(2), 214-225 (2004)
    • (2004) Prostate , vol.59 , Issue.2 , pp. 214-225
    • Gao, S.1    Liu, G.Z.2    Wang, Z.3
  • 47
    • 33947219035 scopus 로고    scopus 로고
    • Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer- derived cell lines
    • DA Benitez, E Pozo-Guisado, A Alvarez-Barrientos, PM Fernandez-Salguero, EA Castellón: Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer- derived cell lines. J Androl 28(2), 282-293 (2007)
    • (2007) J Androl , vol.28 , Issue.2 , pp. 282-293
    • Benitez, D.A.1    Pozo-Guisado, E.2    Alvarez-Barrientos, A.3    Fernandez-Salguero, P.M.4    Castellón, E.A.5
  • 49
    • 77954922243 scopus 로고    scopus 로고
    • Bcl-2 modulates resveratrol-induced ros production by regulating mitochondrial respiration in tumor cells
    • Epub ahead of print
    • IC Low, ZX Chen, S Pervaiz: Bcl-2 Modulates Resveratrol-induced ROS Production by Regulating Mitochondrial Respiration in Tumor Cells. Antioxid Redox Signal [Epub ahead of print] (2010)
    • Antioxid Redox Signal , vol.2010
    • Low, I.C.1    Chen, Z.X.2    Pervaiz, S.3
  • 50
    • 33745089904 scopus 로고    scopus 로고
    • Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3′-kinase/Akt pathway and Bcl-2 family proteins
    • MH Aziz, M Nihal, VX Fu, DF Jarrard, N Ahmad: Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3′-kinase/Akt pathway and Bcl-2 family proteins. Mol Cancer Ther 5(5), 1335-1341 (2006)
    • (2006) Mol Cancer Ther , vol.5 , Issue.5 , pp. 1335-1341
    • Aziz, M.H.1    Nihal, M.2    Fu, V.X.3    Jarrard, D.F.4    Ahmad, N.5
  • 51
    • 4143140856 scopus 로고    scopus 로고
    • Trans-3,4,5′-Trihydroxystibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells
    • Z Cao, J Fang, C Xia, X Shi, BH Jiang : trans-3,4,5′- Trihydroxystibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells. Clin Cancer Res 10(15), 5253-5263 (2004)
    • (2004) Clin Cancer Res , vol.10 , Issue.15 , pp. 5253-5263
    • Cao, Z.1    Fang, J.2    Xia, C.3    Shi, X.4    Jiang, B.H.5
  • 54
    • 3042656673 scopus 로고    scopus 로고
    • Resveratrol suppresses growth of Ishikawa cells through down-regulation of EGF
    • M Kaneuchi, M Sasaki, Y Tanaka, R Yamamoto, N Sakuragi, R Dahiya: Resveratrol suppresses growth of Ishikawa cells through down-regulation of EGF. Int J Oncol 23(4), 1167-1172 (2003)
    • (2003) Int J Oncol , vol.23 , Issue.4 , pp. 1167-1172
    • Kaneuchi, M.1    Sasaki, M.2    Tanaka, Y.3    Yamamoto, R.4    Sakuragi, N.5    Dahiya, R.6
  • 55
    • 33750839605 scopus 로고    scopus 로고
    • Resveratrol interferes with AKT activity and triggers apoptosis in human uterine cancer cells
    • E Sexton, C Van Themsche, K LeBlanc, S Parent, P Lemoine, E Asselin: Resveratrol interferes with AKT activity and triggers apoptosis in human uterine cancer cells. Mol Cancer 5, 45 (2006)
    • (2006) Mol Cancer , vol.5 , pp. 45
    • Sexton, E.1    Van Themsche, C.2    Leblanc, K.3    Parent, S.4    Lemoine, P.5    Asselin, E.6
  • 56
    • 1442326130 scopus 로고    scopus 로고
    • Resveratrol antagonizes EGFR-dependent Erk1/2 activation in human androgenindependent prostate cancer cells with associated isozymeselective PKC alpha inhibition
    • JR Stewart, CA O'Brian: Resveratrol antagonizes EGFR-dependent Erk1/2 activation in human androgenindependent prostate cancer cells with associated isozymeselective PKC alpha inhibition. Invest New Drugs 22(2), 107-117 (2004)
    • (2004) Invest New Drugs , vol.22 , Issue.2 , pp. 107-117
    • Stewart, J.R.1    O'Brian, C.A.2
  • 57
    • 46049093970 scopus 로고    scopus 로고
    • Resveratrol inhibits tumor necrosis factor-alpha-mediated matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells
    • H Yu, C Pan, S Zhao, Z Wang, H Zhang, W Wu: Resveratrol inhibits tumor necrosis factor-alpha-mediated matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells. Biomed Pharmacother 62(6), 366-372 (2008)
    • (2008) Biomed Pharmacother , vol.62 , Issue.6 , pp. 366-372
    • Yu, H.1    Pan, C.2    Zhao, S.3    Wang, Z.4    Zhang, H.5    Wu, W.6
  • 58
    • 33646111188 scopus 로고    scopus 로고
    • Use of resveratrol to improve the effectiveness of cisplatin and doxorubicin: Study in human gynecologic cancer cell lines and in rodent heart
    • YA Rezk, SS Balulad, RS Keller, JA Bennett: Use of resveratrol to improve the effectiveness of cisplatin and doxorubicin: study in human gynecologic cancer cell lines and in rodent heart. Am J Obstet Gynecol 194(5), e23-e26 (2006)
    • (2006) Am J Obstet Gynecol , vol.194 , Issue.5
    • Rezk, Y.A.1    Balulad, S.S.2    Keller, R.S.3    Bennett, J.A.4
  • 59
    • 0036733776 scopus 로고    scopus 로고
    • Suppression of 7,12-Dimethylbenz(a)anthracene-induced Mammary Carcinogenesis in Rats by Resveratrol Role of Nuclear Factor-{kappa}B, Cyclooxygenase 2, and Matrix Metalloprotease 9
    • S Banerjee, C Bueso-Ramos, BB Aggarwal: Suppression of 7,12-Dimethylbenz(a)anthracene-induced Mammary Carcinogenesis in Rats by Resveratrol. Role of Nuclear Factor-{kappa}B, Cyclooxygenase 2, and Matrix Metalloprotease 9. Cancer Research 62, 4945-4954 (2002)
    • (2002) Cancer Research , vol.62 , pp. 4945-4954
    • Banerjee, S.1    Bueso-Ramos, C.2    Aggarwal, B.B.3
  • 60
    • 34248573038 scopus 로고    scopus 로고
    • Non-genomic action of resveratrol on androgen and oestrogen receptors in prostate cancer: Modulation of the phosphoinositide 3-kinase pathway
    • DA Benitez, E Pozo-Guisado, M Clementi, E Castellón, PM Fernandez-Salguero: Non-genomic action of resveratrol on androgen and oestrogen receptors in prostate cancer: modulation of the phosphoinositide 3-kinase pathway. Br J Cancer 96(10), 1595-1604 (2007)
    • (2007) Br J Cancer , vol.96 , Issue.10 , pp. 1595-1604
    • Benitez, D.A.1    Pozo-Guisado, E.2    Clementi, M.3    Castellón, E.4    Fernandez-Salguero, P.M.5
  • 61
    • 70349736107 scopus 로고    scopus 로고
    • Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: Eukaryotic elongation factor 1A2 as a potential target
    • MH Lee, BY Choi, JK Kundu, YK Shin, HK Na, YJ Surh: Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: eukaryotic elongation factor 1A2 as a potential target.Cancer Res 69(18), 7449-7458 (2009)
    • (2009) Cancer Res , vol.69 , Issue.18 , pp. 7449-7458
    • Lee, M.H.1    Choi, B.Y.2    Kundu, J.K.3    Shin, Y.K.4    Na, H.K.5    Surh, Y.J.6
  • 63
    • 58349100590 scopus 로고    scopus 로고
    • Suppression of prostate cancer growth by resveratrol in the transgenic rat for adenocarcinoma of prostate (TRAP) model
    • A Seeni, S Takahashi, K Takeshita, M Tang, S Sugiura, SY Sato, T Shirai: Suppression of prostate cancer growth by resveratrol in the transgenic rat for adenocarcinoma of prostate (TRAP) model. Asian Pac J Cancer Prev 9(1), 7-14 (2008)
    • (2008) Asian Pac J Cancer Prev , vol.9 , Issue.1 , pp. 7-14
    • Seeni, A.1    Takahashi, S.2    Takeshita, K.3    Tang, M.4    Sugiura, S.5    Sato, S.Y.6    Shirai, T.7
  • 64
    • 62549154478 scopus 로고    scopus 로고
    • Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: Inhibition of cell proliferation and induction of apoptosis
    • A Bishayee, N Dhir: Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis. Chem Biol Interact 179(2-3), 131-144 (2009)
    • (2009) Chem Biol Interact , vol.179 , Issue.2-3 , pp. 131-144
    • Bishayee, A.1    Dhir, N.2
  • 65
    • 77953231047 scopus 로고    scopus 로고
    • Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis
    • Epub ahead of print
    • A Bishayee, A Waghray, KF Barnes, T Mbimba, D Bhatia, M Chatterjee, AS Darvesh: Suppression of the Inflammatory Cascade is Implicated in Resveratrol Chemoprevention of Experimental Hepatocarcinogenesis. Pharm Res [Epub ahead of print] (2010)
    • Pharm Res , vol.2010
    • Bishayee, A.1    Waghray, A.2    Barnes, K.F.3    Mbimba, T.4    Bhatia, D.5    Chatterjee, M.6    Darvesh, A.S.7
  • 66
    • 0032994292 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of resveratrol
    • M Jang, JM Pezzuto: Cancer chemopreventive activity of resveratrol. Drugs Exp Clin Res 25(2-3), 65-77 (1999)
    • (1999) Drugs Exp Clin Res , vol.25 , Issue.2-3 , pp. 65-77
    • Jang, M.1    Pezzuto, J.M.2
  • 67
    • 16444382588 scopus 로고    scopus 로고
    • Resveratrol inhibits phorbol ester-induced cyclooxygenase-2 expression in mouse skin: MAPKs and AP-1 as potential molecular targets
    • JK Kundu, KS Chun, SO Kim, YJ Surh: Resveratrol inhibits phorbol ester-induced cyclooxygenase-2 expression in mouse skin: MAPKs and AP-1 as potential molecular targets. Biofactors 21(1-4), 33-39 (2004)
    • (2004) Biofactors , vol.21 , Issue.1-4 , pp. 33-39
    • Kundu, J.K.1    Chun, K.S.2    Kim, S.O.3    Surh, Y.J.4
  • 68
    • 33745728903 scopus 로고    scopus 로고
    • Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity
    • JK Kundu, YK Shin, SH Kim, YJ Surh: Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity. Carcinogenesis 27(7), 1465-1474 (2006)
    • (2006) Carcinogenesis , vol.27 , Issue.7 , pp. 1465-1474
    • Kundu, J.K.1    Shin, Y.K.2    Kim, S.H.3    Surh, Y.J.4
  • 70
    • 0027018318 scopus 로고
    • Cancer incidence in five continents: Classification
    • CS Muir: Cancer incidence in five continents: Classification. IARC Sci Publ 120, 25-30 (1992)
    • (1992) IARC Sci Publ , vol.120 , pp. 25-30
    • Muir, C.S.1
  • 71
    • 0031739933 scopus 로고    scopus 로고
    • Alcohol and other beverage use and prostate cancer risk among Canadian men
    • MG Jain, GT Hislop, GR Howe, JD Burch, P Ghadirian: Alcohol and other beverage use and prostate cancer risk among Canadian men. Int J Cancer 78, 707-711 (1998)
    • (1998) Int J Cancer , vol.78 , pp. 707-711
    • Jain, M.G.1    Hislop, G.T.2    Howe, G.R.3    Burch, J.D.4    Ghadirian, P.5
  • 72
    • 0345256385 scopus 로고    scopus 로고
    • Protective effect of green tea against prostate cancer: A case-control study in southeast China
    • L Jian, LP Xie, AH Lee, CW Binns: Protective effect of green tea against prostate cancer: a case-control study in southeast China. Int J Cancer 108, 130-135 (2004)
    • (2004) Int J Cancer , vol.108 , pp. 130-135
    • Jian, L.1    Xie, L.P.2    Lee, A.H.3    Binns, C.W.4
  • 73
    • 31544473720 scopus 로고    scopus 로고
    • Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: A preliminary report from a one-year proof-ofprinciple study
    • S Bettuzzi, M Brausi, F Rizzi, G Castagnetti, G Peracchia, A Corti: Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-ofprinciple study. Cancer Res 66(2), 1234-1240 (2006)
    • (2006) Cancer Res , vol.66 , Issue.2 , pp. 1234-1240
    • Bettuzzi, S.1    Brausi, M.2    Rizzi, F.3    Castagnetti, G.4    Peracchia, G.5    Corti, A.6
  • 77
    • 0032730946 scopus 로고    scopus 로고
    • Two stages of cancer prevention with green tea
    • H Fujiki: Two stages of cancer prevention with green tea. J Cancer Res Clin Oncol 125, 589-597(1999)
    • (1999) J Cancer Res Clin Oncol , vol.125 , pp. 589-597
    • Fujiki, H.1
  • 79
    • 0030799429 scopus 로고    scopus 로고
    • Inhibition of tumor promoter-induced activator protein-1 activation and cell transformation by tea polyphenols -epigallocatechin gallate and the aflavins
    • Z Dong, W Ma, C Huang, CS Yang: Inhibition of tumor promoter-induced activator protein-1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate and the aflavins. Cancer Res 57, 4414-4419 (1997)
    • (1997) Cancer Res , vol.57 , pp. 4414-4419
    • Dong, Z.1    Ma, W.2    Huang, C.3    Yang, C.S.4
  • 80
    • 0035918278 scopus 로고    scopus 로고
    • Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo
    • S Nam, DM Smith, QP Dou: Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo. J Biol Chem 276, 13322-13330 (2001)
    • (2001) J Biol Chem , vol.276 , pp. 13322-13330
    • Nam, S.1    Smith, D.M.2    Dou, Q.P.3
  • 81
    • 42549158556 scopus 로고    scopus 로고
    • Green tea polyphenol and epigallocatechin gallate induce apoptosis and inhibit invasion in human breast cancer cells
    • RL Thangapazham, N Passi, RK Maheshwari: Green tea polyphenol and epigallocatechin gallate induce apoptosis and inhibit invasion in human breast cancer cells. Cancer Biol Ther 6(12), 1938-1943 (2007)
    • (2007) Cancer Biol Ther , vol.6 , Issue.12 , pp. 1938-1943
    • Thangapazham, R.L.1    Passi, N.2    Maheshwari, R.K.3
  • 82
    • 0037455718 scopus 로고    scopus 로고
    • Inhibition of ultraviolet B-mediated activation of nuclear factor B in normal human epidermal keratinocytes by green tea constituent (-)-epigallocatechin-3-gallate
    • F Afaq, VM Adhami, N Ahmad, H Mukhtar: Inhibition of ultraviolet B-mediated activation of nuclear factor B in normal human epidermal keratinocytes by green tea constituent (-)-epigallocatechin-3-gallate. Oncogene 22, 1035-1044 (2003)
    • (2003) Oncogene , vol.22 , pp. 1035-1044
    • Afaq, F.1    Adhami, V.M.2    Ahmad, N.3    Mukhtar, H.4
  • 83
    • 1942532874 scopus 로고    scopus 로고
    • Essential role of caspases in epigallocatechin-3-gallatemediated inhibition of nuclear factor kB and induction of apoptosis
    • S Gupta, K Hastak, F Afaq, N Ahmad, H Mukhtar: Essential role of caspases in epigallocatechin-3-gallatemediated inhibition of nuclear factor kB and induction of apoptosis. Oncogene 23, 2507-2522 (2004)
    • (2004) Oncogene , vol.23 , pp. 2507-2522
    • Gupta, S.1    Hastak, K.2    Afaq, F.3    Ahmad, N.4    Mukhtar, H.5
  • 84
    • 17644401337 scopus 로고    scopus 로고
    • Epigallocatechin gallate and polyphenon e inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells
    • M Shimizu, A Deguchi, JT Lim, H Moriwaki, L Kopelovich, IB Weinstein: (-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells. Clin Cancer Res 11, 2735-2746 (2005)
    • (2005) Clin Cancer Res , vol.11 , pp. 2735-2746
    • Shimizu, M.1    Deguchi, A.2    Lim, J.T.3    Moriwaki, H.4    Kopelovich, L.5    Weinstein, I.B.6
  • 85
    • 0037108115 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1ß-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes
    • S Ahmed, A Rahman, A Hasnain, M Lalonde, VM Goldberg, TM Haqqi: Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1ß-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes. Free Radic Biol Med 33, 1097-1105 (2002)
    • (2002) Free Radic Biol Med , vol.33 , pp. 1097-1105
    • Ahmed, S.1    Rahman, A.2    Hasnain, A.3    Lalonde, M.4    Goldberg, V.M.5    Haqqi, T.M.6
  • 86
    • 11144333537 scopus 로고    scopus 로고
    • Green tea constituent epigallocatechin-3-gallate selectively inhibits COX-2 without affecting COX-1 expression in human prostate carcinoma cells
    • T Hussain, S Gupta, VM Adhami, H Mukhtar: Green tea constituent epigallocatechin-3-gallate selectively inhibits COX-2 without affecting COX-1 expression in human prostate carcinoma cells. Int J Cancer 113, 660-669 (2005)
    • (2005) Int J Cancer , vol.113 , pp. 660-669
    • Hussain, T.1    Gupta, S.2    Adhami, V.M.3    Mukhtar, H.4
  • 87
    • 33745058978 scopus 로고    scopus 로고
    • AD Le: Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxiaand serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells
    • Q Zhang, X Tang, Q Lu, Z Zhang, J Rao, AD Le: Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxiaand serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells. Mol Cancer Ther 5(5), 1227-1238 (2006)
    • (2006) Mol Cancer Ther , vol.5 , Issue.5 , pp. 1227-1238
    • Zhang, Q.1    Tang, X.2    Lu, Q.3    Zhang, Z.4    Rao, J.5
  • 88
    • 34248363654 scopus 로고    scopus 로고
    • Green tea catechin inhibits ephrin-A1-mediated cell migration and angiogenesis of human umbilical vein endothelial cells
    • FY Tang, EP Chiang, CJ Shih: Green tea catechin inhibits ephrin-A1-mediated cell migration and angiogenesis of human umbilical vein endothelial cells. J Nutr Biochem 18(6), 391-399 (2007)
    • (2007) J Nutr Biochem , vol.18 , Issue.6 , pp. 391-399
    • Tang, F.Y.1    Chiang, E.P.2    Shih, C.J.3
  • 89
    • 17144383220 scopus 로고    scopus 로고
    • VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: Implication for apoptosis resistance
    • YK Lee, TD Shanafelt, ND Bone, AK Strege, DF Jelinek, NE Kay: VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance. Leukemia 19, 513-523 (2005)
    • (2005) Leukemia , vol.19 , pp. 513-523
    • Lee, Y.K.1    Shanafelt, T.D.2    Bone, N.D.3    Strege, A.K.4    Jelinek, D.F.5    Kay, N.E.6
  • 90
    • 0346687606 scopus 로고    scopus 로고
    • Inhibition of the vascularendothelial growth factor-induced intracellular signaling and mitogenesis of human endothelial cells by epigallocatechin-3 gallate
    • T Neuhaus, S Pabst, S Stier, AA Weber, K Schrör, A Sachinidis, H Vetter, YD Ko : Inhibition of the vascularendothelial growth factor-induced intracellular signaling and mitogenesis of human endothelial cells by epigallocatechin-3 gallate. Eur J Pharmacol 483, 223-227(2004)
    • (2004) Eur J Pharmacol , vol.483 , pp. 223-227
    • Neuhaus, T.1    Pabst, S.2    Stier, S.3    Weber, A.A.4    Schrör, K.5    Sachinidis, A.6    Vetter, H.7    Ko, Y.D.8
  • 91
    • 0036842094 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate decreases VEGF production in head and neck and breast carcinoma cells by inhibiting EGFR-related pathways of signal transduction
    • M Masuda, M Suzui, JT Lim, A Deguchi, JW Soh, IB Weinstein: Epigallocatechin-3-gallate decreases VEGF production in head and neck and breast carcinoma cells by inhibiting EGFR-related pathways of signal transduction. J Exp Ther Oncol 2(6), 350-359 (2002)
    • (2002) J Exp Ther Oncol , vol.2 , Issue.6 , pp. 350-359
    • Masuda, M.1    Suzui, M.2    Lim, J.T.3    Deguchi, A.4    Soh, J.W.5    Weinstein, I.B.6
  • 92
    • 66749093527 scopus 로고    scopus 로고
    • Inhibitory effect of (-)-epigallocatechin and (-)-epigallocatechin gallate against heregulin beta1-induced migration/invasion of the MCF-7 breast carcinoma cell line
    • Y Kushima, K Iida, Y Nagaoka, Y Kawaratani, T Shirahama, M Sakaguchi, K Baba, Y Hara, S Uesato: Inhibitory effect of (-)-epigallocatechin and (-)-epigallocatechin gallate against heregulin beta1-induced migration/invasion of the MCF-7 breast carcinoma cell line. Biol Pharm Bull 32(5), 899-904 (2009)
    • (2009) Biol Pharm Bull , vol.32 , Issue.5 , pp. 899-904
    • Kushima, Y.1    Iida, K.2    Nagaoka, Y.3    Kawaratani, Y.4    Shirahama, T.5    Sakaguchi, M.6    Baba, K.7    Hara, Y.8    Uesato, S.9
  • 93
    • 0034282993 scopus 로고    scopus 로고
    • Stimulatory effect of oral administration of green tea or caffeine on ultraviolet light-induced increases in epidermal wildtype p53, p21(WAF1/CIP1), and apoptotic sunburn cells in SKH-1 mice
    • YP Lu, YR Lou, XH Li, JG Xie, D Brash, MT Huang, AH Conney: Stimulatory effect of oral administration of green tea or caffeine on ultraviolet light-induced increases in epidermal wildtype p53, p21(WAF1/CIP1), and apoptotic sunburn cells in SKH-1 mice. Cancer Res 60, 4785-4791 (2000)
    • (2000) Cancer Res , vol.60 , pp. 4785-4791
    • Lu, Y.P.1    Lou, Y.R.2    Li, X.H.3    Xie, J.G.4    Brash, D.5    Huang, M.T.6    Conney, A.H.7
  • 94
    • 3042595837 scopus 로고    scopus 로고
    • Inhibition of lung carcinogenesis and effects on angiogenesis and apoptosis in A/J mice by oral administration of green tea
    • J Liao, GY Yang, ES Park, X Meng, KKL Ho, D Jia, DN Seril, CS Yang: Inhibition of lung carcinogenesis and effects on angiogenesis and apoptosis in A/J mice by oral administration of green tea. Nutr Cancer 48(1), 44-53 (2004)
    • (2004) Nutr Cancer , vol.48 , Issue.1 , pp. 44-53
    • Liao, J.1    Yang, G.Y.2    Park, E.S.3    Meng, X.4    Ho, K.5    Jia, D.6    Seril, D.N.7    Yang, C.S.8
  • 95
    • 0035964175 scopus 로고    scopus 로고
    • Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols
    • USA
    • S Gupta, K Hastak, N Ahmad, JS Lewin, H Mukhtar: Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols. Proc Natl Acad Sci USA 8: 10350-10355 (2001)
    • (2001) Proc Natl Acad Sci , vol.8 , pp. 10350-10355
    • Gupta, S.1    Hastak, K.2    Ahmad, N.3    Lewin, J.S.4    Mukhtar, H.5
  • 96
    • 9244263047 scopus 로고    scopus 로고
    • Oral consumption of green tea polyphenols inhibits insulin-like growth factor-I-induced signaling in an autochthonous mouse model of prostate cancer
    • VM Adhami, IA Siddiqui, N Ahmad, S Gupta, H Mukhtar: Oral consumption of green tea polyphenols inhibits insulin-like growth factor-I-induced signaling in an autochthonous mouse model of prostate cancer. Cancer Res 64, 8715-8722 (2004)
    • (2004) Cancer Res , vol.64 , pp. 8715-8722
    • Adhami, V.M.1    Siddiqui, I.A.2    Ahmad, N.3    Gupta, S.4    Mukhtar, H.5
  • 99
    • 75149132767 scopus 로고    scopus 로고
    • Case-control study on beneficial effect of regular consumption of apples on colorectal cancer risk in a population with relatively low intake of fruits and vegetables
    • W Jedrychowski, U Maugeri, T Popiela, J Kulig, E Sochacka-Tatara, A Pac, A Sowa, A Musial: Case-control study on beneficial effect of regular consumption of apples on colorectal cancer risk in a population with relatively low intake of fruits and vegetables. Eur J Cancer Prev 19(1), 42-47 (2010)
    • (2010) Eur J Cancer Prev , vol.19 , Issue.1 , pp. 42-47
    • Jedrychowski, W.1    Maugeri, U.2    Popiela, T.3    Kulig, J.4    Sochacka-Tatara, E.5    Pac, A.6    Sowa, A.7    Musial, A.8
  • 100
    • 33646250198 scopus 로고    scopus 로고
    • Modulation of oxidative cell damage by reconstituted mixtures of phenolic apple juice extracts in human colon cell lines
    • S Schaefer, M Baum, G Eisenbrand, C Janzowski: Modulation of oxidative cell damage by reconstituted mixtures of phenolic apple juice extracts in human colon cell lines. Mol Nutr Food Res 50(4-5), 413-417 (2006)
    • (2006) Mol Nutr Food Res , vol.50 , Issue.4-5 , pp. 413-417
    • Schaefer, S.1    Baum, M.2    Eisenbrand, G.3    Janzowski, C.4
  • 101
    • 43049118613 scopus 로고    scopus 로고
    • Apple polyphenols modulate expression of selected genes related to toxicological defence and stress response in human colon adenoma cells
    • S Veeriah, C Miene, N Habermann, T Hofmann, S Klenow, J Sauer, F Böhmer, S Wölfl, BL Pool-Zobel. Apple polyphenols modulate expression of selected genes related to toxicological defence and stress response in human colon adenoma cells. Int J Cancer 122(12), 2647-2655 (2008)
    • (2008) Int J Cancer , vol.122 , Issue.12 , pp. 2647-2655
    • Veeriah, S.1    Miene, C.2    Habermann, N.3    Hofmann, T.4    Klenow, S.5    Sauer, J.6    Böhmer, F.7    Wölfl, S.8    Pool-Zobel, B.L.9
  • 102
    • 70350031363 scopus 로고    scopus 로고
    • GSTT2, a phase II gene induced by apple polyphenols, protects colon epithelial cells against genotoxic damage
    • A Petermann, C Miene, G Schulz-Raffelt, K Palige, J Hölzer, M Glei, FD Böhmer: GSTT2, a phase II gene induced by apple polyphenols, protects colon epithelial cells against genotoxic damage. Mol Nutr Food Res 53(10), 1245-1253 (2009)
    • (2009) Mol Nutr Food Res , vol.53 , Issue.10 , pp. 1245-1253
    • Petermann, A.1    Miene, C.2    Schulz-Raffelt, G.3    Palige, K.4    Hölzer, J.5    Glei, M.6    Böhmer, F.D.7
  • 105
    • 58849115079 scopus 로고    scopus 로고
    • Apple phytochemical extracts inhibit proliferation of estrogen-dependent and estrogenindependent human breast cancer cells through cell cycle modulation
    • J Sun, RH Liu: Apple phytochemical extracts inhibit proliferation of estrogen-dependent and estrogenindependent human breast cancer cells through cell cycle modulation. J Agric Food Chem 56(24), 11661-11667 (2008)
    • (2008) J Agric Food Chem , vol.56 , Issue.24 , pp. 11661-11667
    • Sun, J.1    Liu, R.H.2
  • 106
    • 34247571021 scopus 로고    scopus 로고
    • Effect of selected phytochemicals and apple extracts on NF-kappaB activation in human breast cancer MCF-7 cells
    • H Yoon, RH Liu: Effect of selected phytochemicals and apple extracts on NF-kappaB activation in human breast cancer MCF-7 cells. J Agric Food Chem 55(8), 3167-3173 (2007)
    • (2007) J Agric Food Chem , vol.55 , Issue.8 , pp. 3167-3173
    • Yoon, H.1    Liu, R.H.2
  • 107
    • 34250659001 scopus 로고    scopus 로고
    • Triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for apple's anticancer activity
    • X He, RH Liu: Triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for apple's anticancer activity. J Agric Food Chem 55(11), 4366-4370 (2007)
    • (2007) J Agric Food Chem , vol.55 , Issue.11 , pp. 4366-4370
    • He, X.1    Liu, R.H.2
  • 108
    • 77951983939 scopus 로고    scopus 로고
    • Antiproliferative effects of apple peel extract against cancer cells
    • S Reagan-Shaw, D Eggert, H Mukhtar, N Ahmad: Antiproliferative effects of apple peel extract against cancer cells. Nutr Cancer 62(4), 517-524 (2010)
    • (2010) Nutr Cancer , vol.62 , Issue.4 , pp. 517-524
    • Reagan-Shaw, S.1    Eggert, D.2    Mukhtar, H.3    Ahmad, N.4
  • 109
    • 15444371406 scopus 로고    scopus 로고
    • Apples prevent mammary tumors in rats
    • RH Liu, J Liu, B Chen: Apples prevent mammary tumors in rats. J Agric Food Chem 3(6), 2341-2343 (2005)
    • (2005) J Agric Food Chem , vol.3 , Issue.6 , pp. 2341-2343
    • Liu, R.H.1    Liu, J.2    Chen, B.3
  • 111
    • 59849110185 scopus 로고    scopus 로고
    • Fresh apples suppress mammary carcinogenesis and proliferative activity and induce apoptosis in mammary tumors of the Sprague-Dawley rat
    • JR Liu, HW Dong, BQ Chen, P Zhao, RH Liu: Fresh apples suppress mammary carcinogenesis and proliferative activity and induce apoptosis in mammary tumors of the Sprague-Dawley rat. J Agric Food Chem 57(1), 297-304 (2009)
    • (2009) J Agric Food Chem , vol.57 , Issue.1 , pp. 297-304
    • Liu, J.R.1    Dong, H.W.2    Chen, B.Q.3    Zhao, P.4    Liu, R.H.5
  • 112
    • 77952300961 scopus 로고    scopus 로고
    • Ursolic acid attenuates oxidative stressmediated hepatocellular carcinoma induction by diethylnitrosamine in male Wistar rats
    • R Gayathri, DK Priya, GR Gunassekaran, D Sakthisekaran: Ursolic acid attenuates oxidative stressmediated hepatocellular carcinoma induction by diethylnitrosamine in male Wistar rats. Asian Pac J Cancer Prev 10(5), 933-938 (2009)
    • (2009) Asian Pac J Cancer Prev , vol.10 , Issue.5 , pp. 933-938
    • Gayathri, R.1    Priya, D.K.2    Gunassekaran, G.R.3    Sakthisekaran, D.4
  • 113
    • 24944571147 scopus 로고    scopus 로고
    • C Fähndrich, A Bub, H Dietrich, B Watzl, F Will, K Briviba, G Rechkemmer: Cloudy apple juice decreases DNA damage, hyperproliferation and aberrant crypt foci development in the distal colon of DMH-initiated rats
    • SW Barth, C Fähndrich, A Bub, H Dietrich, B Watzl, F Will, K Briviba, G Rechkemmer: Cloudy apple juice decreases DNA damage, hyperproliferation and aberrant crypt foci development in the distal colon of DMH-initiated rats. Carcinogenesis 26(8), 1414-1421 (2005)
    • (2005) Carcinogenesis , vol.26 , Issue.8 , pp. 1414-1421
    • Barth, S.W.1
  • 114
    • 22844436771 scopus 로고    scopus 로고
    • Chemopreventive properties of apple procyanidins on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis
    • F Gossé, S Guyot, S Roussi, A Lobstein, B Fischer, N Seiler, F Raul: Chemopreventive properties of apple procyanidins on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis. Carcinogenesis 26(7), 1291-1295 (2005)
    • (2005) Carcinogenesis , vol.26 , Issue.7 , pp. 1291-1295
    • Gossé, F.1    Guyot, S.2    Roussi, S.3    Lobstein, A.4    Fischer, B.5    Seiler, N.6    Raul, F.7
  • 115
    • 38949214030 scopus 로고    scopus 로고
    • Potentiation of apple procyanidintriggered apoptosis by the polyamine oxidase inactivator MDL 72527 in human colon cancer-derived metastatic cells
    • F Gossé, S Roussi, S Guyot, A Schoenfelder, A Mann, JP Bergerat, N Seiler, F Raul: Potentiation of apple procyanidintriggered apoptosis by the polyamine oxidase inactivator MDL 72527 in human colon cancer-derived metastatic cells. Int J Oncol 29(2), 423-428 (2006)
    • (2006) Int J Oncol , vol.29 , Issue.2 , pp. 423-428
    • Gossé, F.1    Roussi, S.2    Guyot, S.3    Schoenfelder, A.4    Mann, A.5    Bergerat, J.P.6    Seiler, N.7    Raul, F.8
  • 116
    • 0030990628 scopus 로고    scopus 로고
    • Anticarcinogenic action of apple pectin on fecal enzyme activities and mucosal or portal prostaglandin E2 levels in experimental rat colon carcinogenesis
    • K Tazawa, H Okami, I Yamashita, Y Ohnishi, K Kobashi, M Fujimaki: Anticarcinogenic action of apple pectin on fecal enzyme activities and mucosal or portal prostaglandin E2 levels in experimental rat colon carcinogenesis. J Exp Clin Cancer Res 16(1)33-38 (1997)
    • (1997) J Exp Clin Cancer Res , vol.16 , Issue.1 , pp. 33-38
    • Tazawa, K.1    Okami, H.2    Yamashita, I.3    Ohnishi, Y.4    Kobashi, K.5    Fujimaki, M.6
  • 117
    • 0029066820 scopus 로고
    • Effects of apple pectin on fecal bacterial enzymes in azoxymethane-induced rat colon carcinogenesis
    • H Ohkami, K Tazawa, I Yamashita, T Shimizu, K Murai, K Kobashi, M Fujimaki: Effects of apple pectin on fecal bacterial enzymes in azoxymethane-induced rat colon carcinogenesis. Jpn J Cancer Res 86(6), 523-529 (1995)
    • (1995) Jpn J Cancer Res , vol.86 , Issue.6 , pp. 523-529
    • Ohkami, H.1    Tazawa, K.2    Yamashita, I.3    Shimizu, T.4    Murai, K.5    Kobashi, K.6    Fujimaki, M.7
  • 118
    • 0025367269 scopus 로고
    • Serologic precursors of cancer. Retinol, carotenoids, and tocopherol and risk of prostate cancer
    • AW Hsing, GW Comstock, H Abbey, BF Polk: Serologic precursors of cancer. Retinol, carotenoids, and tocopherol and risk of prostate cancer. J Natl Cancer Inst 82(11), 941-946 (1990)
    • (1990) J Natl Cancer Inst , vol.82 , Issue.11 , pp. 941-946
    • Hsing, A.W.1    Comstock, G.W.2    Abbey, H.3    Polk, B.F.4
  • 120
    • 0033559952 scopus 로고    scopus 로고
    • Lower prostate cancer risk in men with elevated plasma lycopene levels: Results of a prospective analysis
    • PH Gann, J Ma, E Giovannucci, W Willett, FM Sacks, CH Hennekens, MJ Stampfer: Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. Cancer Res 59(6), 1225-1230 (1999)
    • (1999) Cancer Res , vol.59 , Issue.6 , pp. 1225-1230
    • Gann, P.H.1    Ma, J.2    Giovannucci, E.3    Willett, W.4    Sacks, F.M.5    Hennekens, C.6    Stampfer, M.J.7
  • 121
    • 0034650166 scopus 로고    scopus 로고
    • Invited commentary: Tomatoes, lycopene, and prostate cancer How strong is the evidence?
    • AR Kristal, JH Cohen: Invited commentary: tomatoes, lycopene, and prostate cancer: How strong is the evidence? Am J Epidemiol 151(2), 124-127 (2000)
    • (2000) Am J Epidemiol , vol.151 , Issue.2 , pp. 124-127
    • Kristal, A.R.1    Cohen, J.H.2
  • 123
    • 73649125017 scopus 로고    scopus 로고
    • Circulating carotenoids, mammographic density, and subsequent risk of breast cancer
    • RM Tamimi, GA Colditz, SE Hankinson: Circulating carotenoids, mammographic density, and subsequent risk of breast cancer. Cancer Res 69(24), 9323-9329 (2009)
    • (2009) Cancer Res , vol.69 , Issue.24 , pp. 9323-9329
    • Tamimi, R.M.1    Colditz, G.A.2    Hankinson, S.E.3
  • 125
    • 33747333302 scopus 로고    scopus 로고
    • Effect of the consumption of tomato paste on plasma prostate-specific antigen levels in patients with benign prostate hyperplasia
    • MS Edinger, WJ Koff: Effect of the consumption of tomato paste on plasma prostate-specific antigen levels in patients with benign prostate hyperplasia. Braz J Med Biol Res 39(8), 1115-1119 (2006)
    • (2006) Braz J Med Biol Res , vol.39 , Issue.8 , pp. 1115-1119
    • Edinger, M.S.1    Koff, W.J.2
  • 127
    • 77957763728 scopus 로고    scopus 로고
    • The carotenoid lycopene differentially regulates phase i and II enzymes in dimethylbenz[a]anthracene-induced MCF-7 cells
    • Epub ahead of print
    • H Wang, LK Leung: The carotenoid lycopene differentially regulates phase I and II enzymes in dimethylbenz[a]anthracene-induced MCF-7 cells. Nutrition [Epub ahead of print] (2010)
    • Nutrition , vol.2010
    • Wang, H.1    Leung, L.K.2
  • 129
    • 34248208035 scopus 로고    scopus 로고
    • Effect of lycopene on insulin-like growth factor-I, IGF binding protein-3 and IGF type-I receptor in prostate cancer cells
    • P Kanagaraj, MR Vijayababu, B Ravisankar, J Anbalagan, MM Aruldhas, J Arunakaran: Effect of lycopene on insulin-like growth factor-I, IGF binding protein-3 and IGF type-I receptor in prostate cancer cells. J Cancer Res Clin Oncol 133(6), 351-359 (2007)
    • (2007) J Cancer Res Clin Oncol , vol.133 , Issue.6 , pp. 351-359
    • Kanagaraj, P.1    Vijayababu, M.R.2    Ravisankar, B.3    Anbalagan, J.4    Aruldhas, M.M.5    Arunakaran, J.6
  • 130
    • 0025955567 scopus 로고
    • Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: Relationship to their cancer chemopreventive action
    • LX Zhang, RV Cooney, JS Bertram: Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: relationship to their cancer chemopreventive action. Carcinogenesis 12(11), 2109-2114 (1991)
    • (1991) Carcinogenesis , vol.12 , Issue.11 , pp. 2109-2114
    • Zhang, L.X.1    Cooney, R.V.2    Bertram, J.S.3
  • 131
    • 34547606014 scopus 로고    scopus 로고
    • Lycopene affects proliferation and apoptosis of four malignant cell lines
    • Jul
    • H Salman, M Bergman, M Djaldetti, H Bessler. Lycopene affects proliferation and apoptosis of four malignant cell lines. Biomed Pharmacother 61(6), 366-369 (2007 Jul)
    • (2007) Biomed Pharmacother , vol.61 , Issue.6 , pp. 366-369
    • Salman, H.1    Bergman, M.2    Djaldetti, M.3    Bessler, H.4
  • 132
    • 33947590535 scopus 로고    scopus 로고
    • Lycopene differentially induces quiescence and apoptosis in androgen-responsive and -independent prostate cancer cell lines
    • NI Ivanov, SP Cowell, P Brown, PS Rennie, ES Guns, ME Cox. Lycopene differentially induces quiescence and apoptosis in androgen-responsive and -independent prostate cancer cell lines. Clin Nutr 26(2), 252-263 (2007)
    • (2007) Clin Nutr , vol.26 , Issue.2 , pp. 252-263
    • Ivanov, N.I.1    Cowell, S.P.2    Brown, P.3    Rennie, P.S.4    Guns, E.S.5    Cox, M.E.6
  • 134
    • 0141513736 scopus 로고    scopus 로고
    • Lycopene increases urokinase receptor and fails to inhibit growth or connexin expression in a metastatically passaged prostate cancer cell line: A brief communication
    • K Forbes, K Gillette, I Sehgal: Lycopene increases urokinase receptor and fails to inhibit growth or connexin expression in a metastatically passaged prostate cancer cell line: a brief communication. Exp Biol Med (Maywood) 228(8), 967-71 (2003)
    • (2003) Exp Biol Med (Maywood) , vol.228 , Issue.8 , pp. 967-971
    • Forbes, K.1    Gillette, K.2    Sehgal, I.3
  • 136
    • 0029127636 scopus 로고
    • Effects of lycopene on spontaneous mammary tumour development in SHN virgin mice
    • H Nagasawa, T Mitamura, S Sakamoto, K Yamamoto: Effects of lycopene on spontaneous mammary tumour development in SHN virgin mice. Anticancer Res 15(4), 1173-1178 (1995)
    • (1995) Anticancer Res , vol.15 , Issue.4 , pp. 1173-1178
    • Nagasawa, H.1    Mitamura, T.2    Sakamoto, S.3    Yamamoto, K.4
  • 137
    • 0041829262 scopus 로고    scopus 로고
    • The potential for strategies using micronutrients and heterocyclic drugs to treat invasive gliomas
    • HK Rooprai, M Christidou, GJ Pilkington: The potential for strategies using micronutrients and heterocyclic drugs to treat invasive gliomas. Acta Neurochir (Wien) 145(8), 683-690 (2003)
    • (2003) Acta Neurochir (Wien) , vol.145 , Issue.8 , pp. 683-690
    • Rooprai, H.K.1    Christidou, M.2    Pilkington, G.J.3
  • 139
    • 0031889526 scopus 로고    scopus 로고
    • Inhibitory effect of tomato juice on rat urinary bladder carcinogenesis after N-butyl-N-(4-hydroxybutyl)nitrosamine initiation
    • E Okajima, M Tsutsumi, S Ozono, H Akai, A Denda, H Nishino, S Oshima, H Sakamoto, Y Konishi: Inhibitory effect of tomato juice on rat urinary bladder carcinogenesis after N-butyl-N-(4-hydroxybutyl)nitrosamine initiation. Jpn J Cancer Res 89(1), 22-26 (1998)
    • (1998) Jpn J Cancer Res , vol.89 , Issue.1 , pp. 22-26
    • Okajima, E.1    Tsutsumi, M.2    Ozono, S.3    Akai, H.4    Denda, A.5    Nishino, H.6    Oshima, S.7    Sakamoto, H.8    Konishi, Y.9
  • 141
    • 0030272801 scopus 로고    scopus 로고
    • Inhibitory effects of natural carotenoids, alpha-carotene, betacarotene, lycopene and lutein, on colonic aberrant crypt foci formation in rats
    • T Narisawa, Y Fukaura, M Hasebe, M Ito, R Aizawa, M Murakoshi, S Uemura, F Khachik, H Nishino: Inhibitory effects of natural carotenoids, alpha-carotene, betacarotene, lycopene and lutein, on colonic aberrant crypt foci formation in rats. Cancer Lett 107(1), 137-142 (1996)
    • (1996) Cancer Lett , vol.107 , Issue.1 , pp. 137-142
    • Narisawa, T.1    Fukaura, Y.2    Hasebe, M.3    Ito, M.4    Aizawa, R.5    Murakoshi, M.6    Uemura, S.7    Khachik, F.8    Nishino, H.9
  • 143
    • 0030726136 scopus 로고    scopus 로고
    • Dietary lycopene decreases the initiation of liver preneoplastic foci by diethylnitrosamine in the rat
    • P Astorg, S Gradelet, R Bergès, M Suschetet: Dietary lycopene decreases the initiation of liver preneoplastic foci by diethylnitrosamine in the rat. Nutr Cancer 29(1), 60-68 (1997)
    • (1997) Nutr Cancer , vol.29 , Issue.1 , pp. 60-68
    • Astorg, P.1    Gradelet, S.2    Bergès, R.3    Suschetet, M.4
  • 145
    • 1342301632 scopus 로고    scopus 로고
    • Effects of tomato sauce consumption on apoptotic cell death in prostate benign hyperplasia and carcinoma
    • HS Kim, P Bowen, L Chen, C Duncan, L Ghosh, R Sharifi, K Christov: Effects of tomato sauce consumption on apoptotic cell death in prostate benign hyperplasia and carcinoma. Nutr Cancer 47(1), 40-47 (2003)
    • (2003) Nutr Cancer , vol.47 , Issue.1 , pp. 40-47
    • Kim, H.S.1    Bowen, P.2    Chen, L.3    Duncan, C.4    Ghosh, L.5    Sharifi, R.6    Christov, K.7
  • 146
    • 33751080151 scopus 로고    scopus 로고
    • Serum testosterone is reduced following short-term phytofluene, lycopene, or tomato powder consumption in F344 rats
    • JK Campbell, CK Stroud, MT Nakamura, MA Lila, JW Erdman Jr: Serum testosterone is reduced following short-term phytofluene, lycopene, or tomato powder consumption in F344 rats. J Nutr 136(11), 2813-2819 (2006)
    • (2006) J Nutr , vol.136 , Issue.11 , pp. 2813-2819
    • Campbell, J.K.1    Stroud, C.K.2    Nakamura, M.T.3    Lila, M.4    Erdman Jr., J.W.5
  • 147
    • 28244492833 scopus 로고    scopus 로고
    • A novel dietary triterpene Lupeol induces fas-mediated apoptotic death of androgensensitive prostate cancer cells and inhibits tumor growth in a xenograft model
    • M Saleem, MH Kweon, JM Yun, VM Adhami, N Khan, DN Syed, H Mukhtar: A novel dietary triterpene Lupeol induces fas-mediated apoptotic death of androgensensitive prostate cancer cells and inhibits tumor growth in a xenograft model. Cancer Res 65(23), 11203-11213 (2005)
    • (2005) Cancer Res , vol.65 , Issue.23 , pp. 11203-11213
    • Saleem, M.1    Kweon, M.H.2    Yun, J.M.3    Adhami, V.M.4    Khan, N.5    Syed, D.N.6    Mukhtar, H.7
  • 148
    • 60849136358 scopus 로고    scopus 로고
    • Lupeol, a dietary triterpene, inhibited growth, and induced apoptosis through down-regulation of DR3 in SMMC7721 cells
    • L Zhang, Y Zhang, L Zhang, X Yang, Z Lv: Lupeol, a dietary triterpene, inhibited growth, and induced apoptosis through down-regulation of DR3 in SMMC7721 cells. Cancer Invest 27(2), 163-170 (2009)
    • (2009) Cancer Invest , vol.27 , Issue.2 , pp. 163-170
    • Zhang, L.1    Zhang, Y.2    Zhang, L.3    Yang, X.4    Lv, Z.5
  • 149
    • 56749185228 scopus 로고    scopus 로고
    • Regulation of signaling pathways involved in lupeol induced inhibition of proliferation and induction of apoptosis in human prostate cancer cells
    • S Prasad, N Nigam, N Kalra, Y Shukla: Regulation of signaling pathways involved in lupeol induced inhibition of proliferation and induction of apoptosis in human prostate cancer cells. Mol Carcinog 47(12), 916-924 (2008)
    • (2008) Mol Carcinog , vol.47 , Issue.12 , pp. 916-924
    • Prasad, S.1    Nigam, N.2    Kalra, N.3    Shukla, Y.4
  • 150
    • 70350317603 scopus 로고    scopus 로고
    • Induction of apoptosis by lupeol in human epidermoid carcinoma A431 cells through regulation of mitochondrial, Akt/PKB and NFkappaB signaling pathways
    • S Prasad, E Madan, N Nigam, P Roy, J George, Y Shukla: Induction of apoptosis by lupeol in human epidermoid carcinoma A431 cells through regulation of mitochondrial, Akt/PKB and NFkappaB signaling pathways. Cancer Biol Ther 8(17), 1632-6139 (2009)
    • (2009) Cancer Biol Ther , vol.8 , Issue.17 , pp. 1632-6139
    • Prasad, S.1    Madan, E.2    Nigam, N.3    Roy, P.4    George, J.5    Shukla, Y.6
  • 153
    • 69549111679 scopus 로고    scopus 로고
    • Lupeol triterpene, a novel diet-based microtubule targeting agent: Disrupts survivin/cFLIP activation in prostate cancer cells
    • M Saleem, I Murtaza, O Witkowsky, AM Kohl, N Maddodi: Lupeol triterpene, a novel diet-based microtubule targeting agent: disrupts survivin/cFLIP
    • (2009) Biochem Biophys Res Commun , vol.388 , Issue.3 , pp. 576-582
    • Saleem, M.1    Murtaza, I.2    Witkowsky, O.3    Kohl, A.M.4    Maddodi, N.5
  • 154
    • 34548763142 scopus 로고    scopus 로고
    • Lupeol suppresses cisplatininduced nuclear factor-kappaB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model
    • TK Lee, RT Poon, JY Wo, S Ma, XY Guan, JN Myers, P Altevogt, AP Yuen: Lupeol suppresses cisplatininduced nuclear factor-kappaB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model. Cancer Res 67, 8800-8809 (2007)
    • (2007) Cancer Res , vol.67 , pp. 8800-8809
    • Lee, T.K.1    Poon, R.T.2    Wo, J.Y.3    Ma, S.4    Guan, X.Y.5    Myers, J.N.6    Altevogt, P.7    Yuen, A.P.8
  • 155
    • 61849102896 scopus 로고    scopus 로고
    • Lupeol induces p53 and cyclin-B-mediated G2/M arrest and targets apoptosis through activation of caspase in mouse skin
    • N Nigam, S Prasad, J George, Y Shukla: Lupeol induces p53 and cyclin-B-mediated G2/M arrest and targets apoptosis through activation of caspase in mouse skin. Biochem Biophys Res Commun 381(2), 253-258 (2009)
    • (2009) Biochem Biophys Res Commun , vol.381 , Issue.2 , pp. 253-258
    • Nigam, N.1    Prasad, S.2    George, J.3    Shukla, Y.4
  • 156
    • 40349087601 scopus 로고    scopus 로고
    • Protective effects of lupeol and mango extract against androgen induced oxidative stress in Swiss albino mice
    • S Prasad, N Kalra, M Singh, Y Shukla: Protective effects of lupeol and mango extract against androgen induced oxidative stress in Swiss albino mice. Asian J Androl 10(2), 313-318 (2008)
    • (2008) Asian J Androl , vol.10 , Issue.2 , pp. 313-318
    • Prasad, S.1    Kalra, N.2    Singh, M.3    Shukla, Y.4
  • 157
    • 38749089810 scopus 로고    scopus 로고
    • Induction of apoptosis by lupeol and mango extract in mouse prostate and LNCaP cells
    • S Prasad, N Kalra, Y Shukla: Induction of apoptosis by lupeol and mango extract in mouse prostate and LNCaP cells. Nutr Cancer 60(1), 120-30 (2008)
    • (2008) Nutr Cancer , vol.60 , Issue.1 , pp. 120-130
    • Prasad, S.1    Kalra, N.2    Shukla, Y.3
  • 158
    • 67650651898 scopus 로고    scopus 로고
    • Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells
    • N Nigam, K Bhui, S Prasad, J George, Y Shukla: [6]-Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells. Chem Biol Interact 181(1), 77-84 (2009)
    • (2009) Chem Biol Interact , vol.181 , Issue.1 , pp. 77-84
    • Nigam, N.1    Bhui, K.2    Prasad, S.3    George, J.4    Shukla, Y.5
  • 159
    • 75749154453 scopus 로고    scopus 로고
    • Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a]P-induced mouse skin tumorigenesis
    • N Nigam, J George, S Srivastava, P Roy, K Bhui, M Singh, Y Shukla: Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a]P-induced mouse skin tumorigenesis. Cancer Chemother Pharmacol 65(4), 687-696 (2010)
    • (2010) Cancer Chemother Pharmacol , vol.65 , Issue.4 , pp. 687-696
    • Nigam, N.1    George, J.2    Srivastava, S.3    Roy, P.4    Bhui, K.5    Singh, M.6    Shukla, Y.7
  • 160
    • 33750685296 scopus 로고    scopus 로고
    • [6]-Gingerol induces cell cycle arrest and cell death of mutant p53-expressing pancreatic cancer cells
    • YJ Park, J Wen, S Bang, SW Park, SY Song: [6]-Gingerol induces cell cycle arrest and cell death of mutant p53-expressing pancreatic cancer cells. Yonsei Med J 47(5), 688-697 (2006)
    • (2006) Yonsei Med J , vol.47 , Issue.5 , pp. 688-697
    • Park, Y.J.1    Wen, J.2    Bang, S.3    Park, S.W.4    Song, S.Y.5
  • 161
    • 40749083585 scopus 로고    scopus 로고
    • Multiple mechanisms are involved in 6- gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells
    • SH Lee, M Cekanova, SJ Baek: Multiple mechanisms are involved in 6- gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells. Mol Carcinog 47, 197-208 (2008)
    • (2008) Mol Carcinog , vol.47 , pp. 197-208
    • Lee, S.H.1    Cekanova, M.2    Baek, S.J.3
  • 162
    • 77957062924 scopus 로고    scopus 로고
    • 6-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun Nterminal kinase pathways in human breast cancer cells
    • Epub ahead of print
    • YL Hsu, CY Chen, MF Hou, EM Tsai, YJ Jong, CH Hung, PL Kuo: 6-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun Nterminal kinase pathways in human breast cancer cells. Mol Nutr Food Res [Epub ahead of print] (2010)
    • (2010) Mol Nutr Food Res
    • Hsu, Y.L.1    Chen, C.Y.2    Hou, M.F.3    Tsai, E.M.4    Jong, Y.J.5    Hung, C.6    Kuo, P.L.7
  • 164
    • 38049068003 scopus 로고    scopus 로고
    • In vitro and in vivo modulation of testosterone mediated alterations in apoptosis related proteins by [6]-gingerol
    • Y Shukla, S Prasad, C Tripathi, M Singh, J George, N Kalra: In vitro and in vivo modulation of testosterone mediated alterations in apoptosis related proteins by [6]-gingerol. Mol Nutr Food Res 51, 1492-1502 (2007)
    • (2007) Mol Nutr Food Res , vol.51 , pp. 1492-1502
    • Shukla, Y.1    Prasad, S.2    Tripathi, C.3    Singh, M.4    George, J.5    Kalra, N.6
  • 165
    • 48649093632 scopus 로고    scopus 로고
    • 6-Shogaol induces apoptosis in human colorectal carcinoma cells via ROS production, caspase activation, and GADD 153 expression
    • Pan MH, Hsieh MC, Kuo JM, Lai CS, Wu H, Sang S, Ho CT. 6-Shogaol induces apoptosis in human colorectal carcinoma cells via ROS production, caspase activation, and GADD 153 expression. Mol Nutr Food Res 52(5): 527-37. (2008)
    • (2008) Mol Nutr Food Res , vol.52 , Issue.5 , pp. 527-537
    • Pan, M.H.1    Hsieh, M.C.2    Kuo, J.M.3    Lai, C.S.4    Wu, H.5    Sang, S.6    Ho, C.T.7
  • 166
    • 21544454944 scopus 로고    scopus 로고
    • Inhibitory effects of [6] gingerly on PMA-induced COX-2 expression and activation of NF-kappaB and p38 MAPK in mouse skin
    • SO Kim, KS Chun, JK Kundu, YJ Surh: Inhibitory effects of [6]-gingerly on PMA-induced COX-2 expression and activation of NF-kappaB and p38 MAPK in mouse skin. Biofactors 21, 27-31 (2004)
    • (2004) Biofactors , vol.21 , pp. 27-31
    • Kim, S.O.1    Chun, K.S.2    Kundu, J.K.3    Surh, Y.J.4
  • 167
    • 57349177876 scopus 로고    scopus 로고
    • Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionineinduced hepatoma rats
    • SH Habib, S Makpol, NA Abdul Hamid, S Das, WZ Ngah, YA Yusof: Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionineinduced hepatoma rats. Clinics (Sao Paulo) 63(6), 807-813 (2008)
    • (2008) Clinics (Sao Paulo) , vol.63 , Issue.6 , pp. 807-813
    • Habib, S.H.1    Makpol, S.2    Abdul Hamid, N.A.3    Das, S.4    Ngah, W.Z.5    Yusof, Y.A.6
  • 168
    • 70350317873 scopus 로고    scopus 로고
    • 6-Shogaol, an Active Constituent of Dietary Ginger, Induces Autophagy by Inhibiting the AKT/mTOR Pathway in Human Non-Small Cell Lung Cancer A549 Cells
    • Epub ahead of print
    • JY Hung, YL Hsu, CT Li, YC Ko, WC Ni, MS Huang, PL Kuo: 6-Shogaol, an Active Constituent of Dietary Ginger, Induces Autophagy by Inhibiting the AKT/mTOR Pathway in Human Non-Small Cell Lung Cancer A549 Cells. J Agric Food Chem [Epub ahead of print] (2009)
    • (2009) J Agric Food Chem
    • Hung, J.Y.1    Hsu, Y.L.2    Li, C.T.3    Ko, Y.C.4    Ni, W.C.5    Huang, M.S.6    Kuo, P.L.7
  • 169
    • 0035110888 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6] gingerol
    • AM Bode, WY Ma, YJ Surh, Z Dong: Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6]-gingerol. Cancer Res 61, 850-853 (2001)
    • (2001) Cancer Res , vol.61 , pp. 850-853
    • Bode, A.M.1    Ma, W.Y.2    Surh, Y.J.3    Dong, Z.4
  • 170
  • 171
    • 65649106460 scopus 로고    scopus 로고
    • Ginger's (Zingiber officinale Roscoe) inhibition of rat colonic adenocarcinoma cells proliferation and angiogenesis in vitro
    • AC Brown, C Shah, J Liu, JT Pham, JG Zhang, MR Jadus: Ginger's (Zingiber officinale Roscoe) inhibition of rat colonic adenocarcinoma cells proliferation and angiogenesis in vitro. Phytother Res 23(5), 640-645 (2009)
    • (2009) Phytother Res , vol.23 , Issue.5 , pp. 640-645
    • Brown, A.C.1    Shah, C.2    Liu, J.3    Pham, J.T.4    Zhang, J.G.5    Jadus, M.R.6
  • 172
    • 0030042774 scopus 로고    scopus 로고
    • Inhibition of tumor promotion in SENCAR mouse skin by ethanol extract of Zingiber officinale rhizome
    • SK Katiyar, R Agarwal, H Mukhtar: Inhibition of tumor promotion in SENCAR mouse skin by ethanol extract of Zingiber officinale rhizome. Cancer Res 56(5), 1023-1030 (1996)
    • (1996) Cancer Res , vol.56 , Issue.5 , pp. 1023-1030
    • Katiyar, S.K.1    Agarwal, R.2    Mukhtar, H.3
  • 173
  • 174
    • 0032547010 scopus 로고    scopus 로고
    • Inhibitory effects of [6] gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice
    • KK Park, KS Chun, JM Lee, SS Lee, YJ Surh: Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice. Cancer Lett 129(2), 139-144 (1998)
    • (1998) Cancer Lett , vol.129 , Issue.2 , pp. 139-144
    • Park, K.K.1    Chun, K.S.2    Lee, J.M.3    Lee, S.S.4    Surh, Y.J.5
  • 175
    • 17844362777 scopus 로고    scopus 로고
    • [6] -Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin
    • SO Kim, JK Kundu, YK Shin, JH Park, MH Cho, TY Kim, YJ Surh: [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin. Oncogene 24(15), 2558-2567 (2005)
    • (2005) Oncogene , vol.24 , Issue.15 , pp. 2558-2567
    • Kim, S.O.1    Kundu, J.K.2    Shin, Y.K.3    Park, J.H.4    Cho, M.H.5    Kim, T.Y.6    Surh, Y.J.7
  • 176
    • 34047135039 scopus 로고    scopus 로고
    • [6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo
    • JK Kim, Y Kim, KM Na, YJ Surh, TY Kim: [6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo. Free Radic Res 41(5), 603-614 (2007)
    • (2007) Free Radic Res , vol.41 , Issue.5 , pp. 603-614
    • Kim, J.K.1    Kim, Y.2    Na, K.M.3    Surh, Y.J.4    Kim, T.Y.5
  • 177
    • 0035922173 scopus 로고    scopus 로고
    • Antioxidative and antitumor promoting effects of [6] paradol and its homologs
    • WY Chung, YJ Jung, YJ Surh, SS Lee, KK Park: Antioxidative and antitumor promoting effects of [6]-paradol and its homologs. Mutat Res 496(1-2), 199-206 (2001)
    • (2001) Mutat Res , vol.496 , Issue.1-2 , pp. 199-206
    • Chung, W.Y.1    Jung, Y.J.2    Surh, Y.J.3    Lee, S.S.4    Park, K.K.5
  • 178
    • 0028925916 scopus 로고
    • Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture
    • DJ Morre, PJ Chueh, DM Morre: Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture. Proc Natl Acad Sci USA 92, 1831-1835 (1995)
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1831-1835
    • Morre, D.J.1    Chueh, P.J.2    Morre, D.M.3
  • 180
    • 0035946942 scopus 로고    scopus 로고
    • Capsaicin potentiates 1, 25-dihydoxyvitamin D3- and all-trans retinoic acidinduced differentiation of human promyelocytic leukemia HL-60 cells
    • SN Kang, SW Chung, TS Kim: Capsaicin potentiates 1, 25-dihydoxyvitamin D3- and all-trans retinoic acidinduced differentiation of human promyelocytic leukemia HL-60 cells. Eur J Pharmacol 420(2-3), 83-90 (2001)
    • (2001) Eur J Pharmacol , vol.420 , Issue.2-3 , pp. 83-90
    • Kang, S.N.1    Chung, S.W.2    Kim, T.S.3
  • 181
    • 0037355052 scopus 로고    scopus 로고
    • Capsaicin inhibits growth of adult T-cell leukemia cells
    • J Zhang, M Nagasaki, Y Tanaka, S Morikawa: Capsaicin inhibits growth of adult T-cell leukemia cells. Leuk Res 27, 275-283 (2003)
    • (2003) Leuk Res , vol.27 , pp. 275-283
    • Zhang, J.1    Nagasaki, M.2    Tanaka, Y.3    Morikawa, S.4
  • 182
    • 0030713333 scopus 로고    scopus 로고
    • Capsaicin can alter the expression of tumor formingrelated genes which might be followed by induction of apoptosis of a Korean stomach cancer cell line, SNU-1
    • JD Kim, JM Kim, JO Pyo, SY Kim, BS Kim, R Yu, IS Han: Capsaicin can alter the expression of tumor formingrelated genes which might be followed by induction of apoptosis of a Korean stomach cancer cell line, SNU-1. Cancer Lett 120, 235-241 (1997)
    • (1997) Cancer Lett , vol.120 , pp. 235-241
    • Kim, J.D.1    Kim, J.M.2    Pyo, J.O.3    Kim, S.Y.4    Kim, B.S.5    Yu, R.6    Han, I.S.7
  • 185
    • 74049102383 scopus 로고    scopus 로고
    • Effect of capsaicin on tNOX (ENOX2) protein expression in stomach cancer cells
    • HM Wang, PJ Chueh, SP Chang, CL Yang, KN Shao: Effect of capsaicin on tNOX (ENOX2) protein expression in stomach cancer cells. Biofactors 34(3), 209-217 (2009)
    • (2009) Biofactors , vol.34 , Issue.3 , pp. 209-217
    • Wang, H.M.1    Chueh, P.J.2    Chang, S.P.3    Yang, C.L.4    Shao, K.N.5
  • 186
    • 77649187285 scopus 로고    scopus 로고
    • Capsaicin mediates cell death in bladder cancer T24 cells through reactive oxygen species production and mitochondrial depolarization
    • ZH Yang, XH Wang, HP Wang, LQ Hu, XM Zheng, SW Li: Capsaicin mediates cell death in bladder cancer T24 cells through reactive oxygen species production and mitochondrial depolarization. Urology 75(3), 735-741 (2010)
    • (2010) Urology , vol.75 , Issue.3 , pp. 735-741
    • Yang, Z.1    Wang, X.H.2    Wang, H.P.3    Hu, L.Q.4    Zheng, X.M.5    Li, S.W.6
  • 187
    • 74449084136 scopus 로고    scopus 로고
    • Capsaicin causes cell-cycle arrest and apoptosis in ERpositive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway
    • NH Thoennissen, J O'Kelly, D Lu, GB Iwanski, DT La, S Abbassi, A Leiter, B Karlan, R Mehta, HP Koeffler: Capsaicin causes cell-cycle arrest and apoptosis in ERpositive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway. Oncogene 29(2), 285-296 (2010)
    • (2010) Oncogene , vol.29 , Issue.2 , pp. 285-296
    • Thoennissen, N.H.1    O'Kelly, J.2    Lu, D.3    Iwanski, G.B.4    La S Abbassi, D.T.5    Leiter, A.6    Karlan, B.7    Mehta, R.8    Koeffler, H.P.9
  • 188
    • 4644295000 scopus 로고    scopus 로고
    • Capsaicin, a spicy component of hot pepper, induces apoptosis by activation of the peroxisome proliferator-activated receptor gamma in HT-29 human colon cancer cells
    • CS Kim, WH Park, JY Park, JH Kang, MO Kim, T Kawada, H Yoo, IS Han, R Yu: Capsaicin, a spicy component of hot pepper, induces apoptosis by activation of the peroxisome proliferator-activated receptor gamma in HT-29 human colon cancer cells. J Med Food 7(3), 267-273 (2004)
    • (2004) J Med Food , vol.7 , Issue.3 , pp. 267-273
    • Kim, C.S.1    Park, W.H.2    Park, J.Y.3    Kang, J.H.4    Kim, M.O.5    Kawada, T.6    Yoo, H.7    Han, I.S.8    Yu, R.9
  • 189
    • 0037428673 scopus 로고    scopus 로고
    • Roles of JNK-1 and p38 in selective induction of apoptosis by capsaicin in ras-transformed human breast epithelial cells
    • HJ Kang, Y Soh, MS Kim, EJ Lee, YJ Surh, HR Kim, SH Kim, A Moon: Roles of JNK-1 and p38 in selective induction of apoptosis by capsaicin in ras-transformed human breast epithelial cells. Int J Cancer 103(4), 475-482 (2003)
    • (2003) Int J Cancer , vol.103 , Issue.4 , pp. 475-482
    • Kang, H.J.1    Soh, Y.2    Kim, M.S.3    Lee, E.J.4    Surh, Y.J.5    Kim, H.R.6    Kim, S.H.7    Moon, A.8
  • 190
    • 0034490854 scopus 로고    scopus 로고
    • Inhibitory effects of curcumin and capsaicin on phorbol ester-induced activation of eukaryotic transcription factors, NF-kB and AP-1
    • Y-J Surh, SS Han, Y-S Keum, H-J Seo, SS Lee: Inhibitory effects of curcumin and capsaicin on phorbol ester-induced activation of eukaryotic transcription factors, NF-kB and AP-1. Biofactors 12,107-112 (2000)
    • (2000) Biofactors , vol.12 , pp. 107-112
    • Surh, Y.-J.1    Han, S.S.2    Keum, Y.-S.3    Seo, H.-J.4    Lee, S.S.5
  • 191
    • 0030588541 scopus 로고    scopus 로고
    • Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is a potent inhibitor of nuclear transcription factor-kappa B activation by diverse agents
    • S Singh, K Natarajan, BB Aggarwal: Capsaicin (8-methyl-N-vanillyl-6- nonenamide) is a potent inhibitor of nuclear transcription factor-kappa B activation by diverse agents. J Immunol 157, 4412-4420 (1996)
    • (1996) J Immunol , vol.157 , pp. 4412-4420
    • Singh, S.1    Natarajan, K.2    Aggarwal, B.B.3
  • 193
    • 57349126316 scopus 로고    scopus 로고
    • Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathway
    • DH Shin, OH Kim, HS Jun, MK Kang: Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathway. Exp Mol Med 40(5), 486-494 (2008)
    • (2008) Exp Mol Med , vol.40 , Issue.5 , pp. 486-494
    • Shin, D.H.1    Kim, O.H.2    Jun, H.S.3    Kang, M.K.4
  • 194
    • 0026502351 scopus 로고
    • Studies on capsaicin inhibition of chemically-induced lipid peroxidation in the lung and liver tissues of rat
    • AK De, JJ Ghosh: Studies on capsaicin inhibition of chemically-induced lipid peroxidation in the lung and liver tissues of rat. Phytotherapy Research 6, 34-37 (1992)
    • (1992) Phytotherapy Research , vol.6 , pp. 34-37
    • De, A.K.1    Ghosh, J.J.2
  • 195
    • 0009481159 scopus 로고    scopus 로고
    • Capsaicin inhibits exercise induced lipid peroxidation in cardiac and skeletal muscles of rat
    • C Toskulkao, S Tekittipong: Capsaicin inhibits exercise induced lipid peroxidation in cardiac and skeletal muscles of rat. Phytotherapy Research 6: 34-37 (1996)
    • (1996) Phytotherapy Research , vol.6 , pp. 34-37
    • Toskulkao, C.1    Tekittipong, S.2
  • 196
    • 0029069908 scopus 로고
    • Effect of capsaicin and chilli on ethanol induced gastric mucosal injury in the rat
    • JY Kang, CT Teng, A Wee, FC Chen: Effect of capsaicin and chilli on ethanol induced gastric mucosal injury in the rat. Gut 36, 664-669 (1995)
    • (1995) Gut , vol.36 , pp. 664-669
    • Kang, J.Y.1    Teng, C.T.2    Wee, A.3    Chen, F.C.4
  • 197
    • 0034634270 scopus 로고    scopus 로고
    • Capsaicin protects against ethanol-induced oxidative injury in the gastrointestinal mucosa of rats
    • JS Park, MA Choi, BS Kim, IS Han, T Kurata, R Yu: Capsaicin protects against ethanol-induced oxidative injury in the gastrointestinal mucosa of rats. Life Sciences 67, 3087-3093 (2000)
    • (2000) Life Sciences , vol.67 , pp. 3087-3093
    • Park, J.S.1    Choi, M.2    Kim, B.S.3    Han, I.S.4    Kurata, T.5    Yu, R.6
  • 198
    • 0030994775 scopus 로고    scopus 로고
    • Effects of capsaicin on chemically induced two-stage mouse skin carcinogenesis
    • KK Park, YJ Surh: Effects of capsaicin on chemically induced two-stage mouse skin carcinogenesis. Cancer Lett 114, 183-184 (1997)
    • (1997) Cancer Lett , vol.114 , pp. 183-184
    • Park, K.K.1    Surh, Y.J.2
  • 199
    • 0035953182 scopus 로고    scopus 로고
    • Capsaicin suppresses phorbol ester-induced activation of NFkB/ Rel and AP-1 transcription factors in sedmis
    • SS Han, YS Keum, HJ Seo, KS Chun, SS Lee, YJ Surh: Capsaicin suppresses phorbol ester-induced activation of NFkB/ Rel and AP-1 transcription factors in sedmis. Cancer Lett 164, 119-126 (2001)
    • (2001) Cancer Lett , vol.164 , pp. 119-126
    • Han, S.S.1    Keum, Y.S.2    Seo, H.J.3    Chun, K.S.4    Lee, S.S.5    Surh, Y.J.6
  • 200
    • 56349151331 scopus 로고    scopus 로고
    • In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway
    • R Zhang, I Humphreys, RP Sahu, Y Shi, SK Srivastava: In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway. Apoptosis 13(12), 1465-1478 (2008)
    • (2008) Apoptosis , vol.13 , Issue.12 , pp. 1465-1478
    • Zhang, R.1    Humphreys, I.2    Sahu, R.P.3    Shi, Y.4    Srivastava, S.K.5
  • 201
    • 74049129532 scopus 로고    scopus 로고
    • Capsaicin alleviates the imbalance in xenobiotic metabolizing enzymes and tumor markers during experimental lung tumorigenesis
    • P Anandakumar, S Kamaraj, S Jagan, G Ramakrishnan, C Naveenkumar, S Asokkumar, T Devaki: Capsaicin alleviates the imbalance in xenobiotic metabolizing enzymes and tumor markers during experimental lung tumorigenesis. Mol Cell Biochem 331(1-2), 135-143 (2009)
    • (2009) Mol Cell Biochem , vol.331 , Issue.1-2 , pp. 135-143
    • Anandakumar, P.1    Kamaraj, S.2    Jagan, S.3    Ramakrishnan, G.4    Naveenkumar, C.5    Asokkumar, S.6    Devaki, T.7
  • 202
    • 77649180336 scopus 로고    scopus 로고
    • Bromelain's activity and potential as an anti-cancer agent: Current evidence and perspectives
    • K Chobotova, AB Vernallis, FA Majid: Bromelain's activity and potential as an anti-cancer agent: Current evidence and perspectives. Cancer Lett 290(2), 148-156 (2010)
    • (2010) Cancer Lett , vol.290 , Issue.2 , pp. 148-156
    • Chobotova, K.1    Vernallis, A.B.2    Majid, F.A.3
  • 203
    • 0023954191 scopus 로고
    • Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application: An update
    • SJ Taussig, S Batkin: Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application: An update. J Ethnopharmacol 22, 191-203 (1988)
    • (1988) J Ethnopharmacol , vol.22 , pp. 191-203
    • Taussig, S.J.1    Batkin, S.2
  • 204
    • 0015452986 scopus 로고
    • [Anticancer treatment and bromelains]
    • G Gerard: [Anticancer treatment and bromelains]. Agressologie 13(4), 261-274 (1972)
    • (1972) Agressologie , vol.13 , Issue.4 , pp. 261-274
    • Gerard, G.1
  • 205
    • 0022353891 scopus 로고
    • Inhibition of Tumour Growth in vitro by Bromelain: An Extract of the Pineapple Plant (Ananas comosus)
    • SJ Taussig, J Szekerczes, S Batkin: Inhibition of Tumour Growth in vitro by Bromelain: an Extract of the Pineapple Plant (Ananas comosus). Planta Med 51(6), 538-539 (1985)
    • (1985) Planta Med , vol.51 , Issue.6 , pp. 538-539
    • Taussig, S.J.1    Szekerczes, J.2    Batkin, S.3
  • 206
    • 0023720671 scopus 로고
    • Antimetastatic effect of bromelain with or without its proteolytic and anticoagulant activity
    • S Batkin, SJ Taussig, J Szekerezes: Antimetastatic effect of bromelain with or without its proteolytic and anticoagulant activity. J Cancer Res Clin Oncol 114, 507 (1988)
    • (1988) J Cancer Res Clin Oncol , vol.114 , pp. 507
    • Batkin, S.1    Taussig, S.J.2    Szekerezes, J.3
  • 207
    • 16344363014 scopus 로고    scopus 로고
    • Modulation of murine tumor growth and colonization by bromelaine: An extract of the pineapple plant (Ananas comosum L.)
    • J Beuth, JM Braun: Modulation of murine tumor growth and colonization by bromelaine: an extract of the pineapple plant (Ananas comosum L.). In vivo 19(2), 483-485 (2005)
    • (2005) In Vivo , vol.19 , Issue.2 , pp. 483-485
    • Beuth, J.1    Braun, J.M.2
  • 208
    • 36849030829 scopus 로고    scopus 로고
    • Regulation of p53, nuclear factor kappaB and cyclooxygenase-2 expression by bromelain through targeting mitogen-activated protein kinase pathway in mouse skin
    • N Kalra, K Bhui, P Roy, S Srivastava, J George, S Prasad, Y Shukla: Regulation of p53, nuclear factor kappaB and cyclooxygenase-2 expression by bromelain through targeting mitogen-activated protein kinase pathway in mouse skin. Toxicol Appl Pharmacol 226(1), 30-37 (2008)
    • (2008) Toxicol Appl Pharmacol , vol.226 , Issue.1 , pp. 30-37
    • Kalra, N.1    Bhui, K.2    Roy, P.3    Srivastava, S.4    George, J.5    Prasad, S.6    Shukla, Y.7
  • 209
    • 67649968417 scopus 로고    scopus 로고
    • Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumor-initiation triggering mitochondrial death pathway
    • K Bhui, S Prasad, J George, Y Shukla: Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumor-initiation triggering mitochondrial death pathway. Cancer Lett 282(2), 167-176 (2009)
    • (2009) Cancer Lett , vol.282 , Issue.2 , pp. 167-176
    • Bhui, K.1    Prasad, S.2    George, J.3    Shukla, Y.4
  • 210
    • 0033227511 scopus 로고    scopus 로고
    • Effects of oral bromelain administration on the impaired immunocytotoxicity of mononuclear cells from mammary tumor patients
    • K Eckert, E Grabowska, R Stange, U Schneider, K Eschmann, HR Maurer: Effects of oral bromelain administration on the impaired immunocytotoxicity of mononuclear cells from mammary tumor patients. Oncol Rep 6(6), 1191-1199 (1999)
    • (1999) Oncol Rep , vol.6 , Issue.6 , pp. 1191-1199
    • Eckert, K.1    Grabowska, E.2    Stange, R.3    Schneider, U.4    Eschmann, K.5    Maurer, H.R.6
  • 212
    • 0037236792 scopus 로고    scopus 로고
    • Anticancer potential of curcumin: Preclinical and clinical studies
    • BB Aggarwal, A Kumar, AC Bharti: Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res 23: 363-398 (2003)
    • (2003) Anticancer Res , vol.23 , pp. 363-398
    • Aggarwal, B.B.1    Kumar, A.2    Bharti, A.C.3
  • 213
    • 11844302922 scopus 로고    scopus 로고
    • Constitutive activation of transcription factor AP-1 in cervical cancer and suppression of human papillomavirus (HPV) transcription and AP-1 activity in HeLa cells by curcumin
    • BK Prusty, BC Das: Constitutive activation of transcription factor AP-1 in cervical cancer and suppression of human papillomavirus (HPV) transcription and AP-1 activity in HeLa cells by curcumin. Int J Cancer 113(6), 951-960 (2005)
    • (2005) Int J Cancer , vol.113 , Issue.6 , pp. 951-960
    • Prusty, B.K.1    Das, B.C.2
  • 214
    • 33646730760 scopus 로고    scopus 로고
    • Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis
    • CS Divya, MR Pillai: Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis. Mol Carcinog 45(5), 320-332 (2006)
    • (2006) Mol Carcinog , vol.45 , Issue.5 , pp. 320-332
    • Divya, C.S.1    Pillai, M.R.2
  • 215
    • 0028867742 scopus 로고
    • Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]
    • S Singh, BB Aggarwal: Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J Biol Chem 270, 24995-25000 (1995)
    • (1995) J Biol Chem , vol.270 , pp. 24995-25000
    • Singh, S.1    Aggarwal, B.B.2
  • 217
    • 0029147685 scopus 로고
    • Postnatal modulation of hepatic biotransformation system enzymes via translactational exposure of F1 mouse pups to turmeric and curcumin
    • A Singh, SP Singh, R Bamezai: Postnatal modulation of hepatic biotransformation system enzymes via translactational exposure of F1 mouse pups to turmeric and curcumin. Cancer Lett 96(1), 87-93 (1995)
    • (1995) Cancer Lett , vol.96 , Issue.1 , pp. 87-93
    • Singh, A.1    Singh, S.P.2    Bamezai, R.3
  • 218
    • 0026029402 scopus 로고
    • Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis
    • MT Huang, T Lusz, T Ferraro, TF Abidi, JD Laskin, AH Conney: Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Research 51, 813-819 (1991)
    • (1991) Cancer Research , vol.51 , pp. 813-819
    • Huang, M.T.1    Lusz, T.2    Ferraro, T.3    Abidi, T.F.4    Laskin, J.D.5    Conney, A.H.6
  • 219
    • 33646877856 scopus 로고    scopus 로고
    • Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells
    • Z Wang, Y Zhang, S Banerjee, Y Li, FH Sarkar: Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells. Cancer 106(11), 2503-2513 (2006)
    • (2006) Cancer , vol.106 , Issue.11 , pp. 2503-2513
    • Wang, Z.1    Zhang, Y.2    Banerjee, S.3    Li, Y.4    Sarkar, F.H.5
  • 220
    • 0141955061 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells
    • AC Bharti, N Donato, BB Aggarwal: Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells. J Immunol 171, 3863-3871 (2003)
    • (2003) J Immunol , vol.171 , pp. 3863-3871
    • Bharti, A.C.1    Donato, N.2    Aggarwal, B.B.3
  • 221
    • 0037299799 scopus 로고    scopus 로고
    • Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells
    • MS Squires, EA Hudson, L Howells, S Sale, CE Houghton, JL Jones, LH Fox, M Dickens, SA Prigent, MM Manson: Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells. Biochem Pharmacol 65(3), 361-376 (2003)
    • (2003) Biochem Pharmacol , vol.65 , Issue.3 , pp. 361-376
    • Squires, M.S.1    Hudson, E.A.2    Howells, L.3    Sale, S.4    Houghton, C.E.5    Jones, J.L.6    Fox, L.H.7    Dickens, M.8    Prigent, S.A.9    Manson, M.M.10
  • 223
    • 23044494635 scopus 로고    scopus 로고
    • Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria
    • X Gao, D Deeb, H Jiang, YB Liu, SA Dulchavsky, SC Gautam: Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria. J Exp Ther Oncol 5(1), 39-48 (2005)
    • (2005) J Exp Ther Oncol , vol.5 , Issue.1 , pp. 39-48
    • Gao, X.1    Deeb, D.2    Jiang, H.3    Liu, Y.B.4    Dulchavsky, S.A.5    Gautam, S.C.6
  • 224
    • 0027189562 scopus 로고
    • Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol- 13-acetateinduced increase in ornithine decarboxylase mRNA in mouse epidermis
    • YP Lu, RL Chang, MT Huang, AH Conney: Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol- 13-acetateinduced increase in ornithine decarboxylase mRNA in mouse epidermis. Carcinogenesis 14, 293-297 (1993)
    • (1993) Carcinogenesis , vol.14 , pp. 293-297
    • Lu, Y.P.1    Chang, R.L.2    Huang, M.T.3    Conney, A.H.4
  • 225
    • 0031418195 scopus 로고    scopus 로고
    • Inhibitory effects of topical application of low doses of curcumin on 12-Otetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis
    • MT Huang, W Ma, P Yen, JG Xie, J Han, K Frenkel, D Grunberger, AH Conney: Inhibitory effects of topical application of low doses of curcumin on 12-Otetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis. Carcinogenesis 18, 83-88 (1997)
    • (1997) Carcinogenesis , vol.18 , pp. 83-88
    • Huang, M.T.1    Ma, W.2    Yen, P.3    Xie, J.G.4    Han, J.5    Frenkel, K.6    Grunberger, D.7    Conney, A.H.8
  • 226
  • 227
    • 0028043644 scopus 로고
    • Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger RNAs in mouse skin
    • SS Kakar, D Roy: Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger RNAs in mouse skin. Cancer Lett 87, 85-89 (1994)
    • (1994) Cancer Lett , vol.87 , pp. 85-89
    • Kakar, S.S.1    Roy, D.2
  • 228
    • 0028872989 scopus 로고
    • Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound
    • CV Rao, A Rivenson, B Simi, BS Reddy: Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res 55(2), 259-266 (1995)
    • (1995) Cancer Res , vol.55 , Issue.2 , pp. 259-266
    • Rao, C.V.1    Rivenson, A.2    Simi, B.3    Reddy, B.S.4
  • 229
    • 0030939425 scopus 로고    scopus 로고
    • The dietary pigment curcumin reduces endothelial tissue factor gene expression by inhibiting binding of AP-1 to the DNA and activation of NF-kappa B
    • A Bierhaus, Y Zhang, P Quehenberger, T Luther, M Haase, M Müller, N Mackman, R Ziegler, PP Nawroth: The dietary pigment curcumin reduces endothelial tissue factor gene expression by inhibiting binding of AP-1 to the DNA and activation of NF-kappa B. Thromb Haemost 77(4), 772-782 (1997)
    • (1997) Thromb Haemost , vol.77 , Issue.4 , pp. 772-782
    • Bierhaus, A.1    Zhang, Y.2    Quehenberger, P.3    Luther, T.4    Haase, M.5    Müller, M.6    Mackman, N.7    Ziegler, R.8    Nawroth, P.P.9
  • 233
    • 0034718294 scopus 로고    scopus 로고
    • Isothiocyanates, glutathione Stransferase M1 and T1 polymorphisms and lung cancer risk: A prospective study of men in Shanghai, China
    • SJ London, J-M Yuan, FL Chung, YT Gao, GA Coetzee, MC Yu, RK Ross: Isothiocyanates, glutathione Stransferase M1 and T1 polymorphisms and lung cancer risk: a prospective study of men in Shanghai, China. Lancet 356, 724-729 (2000)
    • (2000) Lancet , vol.356 , pp. 724-729
    • London, S.J.1    Yuan, J.-M.2    Chung, F.L.3    Gao, Y.T.4    Coetzee, G.A.5    Yu, M.C.6    Ross, R.K.7
  • 235
    • 0142062138 scopus 로고    scopus 로고
    • Chapter 17: Genital human papillomavirus infections - Current and prospective therapies
    • M Stanley: Chapter 17: Genital human papillomavirus infections - current and prospective therapies. J Natl Cancer Inst Monogr 117-124 (2003)
    • (2003) J Natl Cancer Inst Monogr , pp. 117-124
    • Stanley, M.1
  • 237
    • 0031755999 scopus 로고    scopus 로고
    • Dietary indole derivatives induce apoptosis in human breast cancer cells
    • FA Fares, X Ge, S Yannai, G Rennert: Dietary indole derivatives induce apoptosis in human breast cancer cells. Adv Exp Med Biol 451, 153-157 (1998)
    • (1998) Adv Exp Med Biol , vol.451 , pp. 153-157
    • Fares, F.A.1    Ge, X.2    Yannai, S.3    Rennert, G.4
  • 238
    • 0032512820 scopus 로고    scopus 로고
    • Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling
    • CM Cover, SJ Hsieh, SH Tran, G Hallden, GS Kim, LF Bjeldanes, GL Firestone: Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling. J Biol Chem 273, 3838-3847 (1998)
    • (1998) J Biol Chem , vol.273 , pp. 3838-3847
    • Cover, C.M.1    Hsieh, S.J.2    Tran, S.H.3    Hallden, G.4    Kim, G.S.5    Bjeldanes, L.F.6    Firestone, G.L.7
  • 239
    • 0035942499 scopus 로고    scopus 로고
    • Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells
    • SR Chinni, Y Li, S Upadhyay, PK Koppolu, FH Sarkar: Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells. Oncogene 20(23), 2927-2936 (2001)
    • (2001) Oncogene , vol.20 , Issue.23 , pp. 2927-2936
    • Chinni, S.R.1    Li, Y.2    Upadhyay, S.3    Koppolu, P.K.4    Sarkar, F.H.5
  • 240
    • 0035208658 scopus 로고    scopus 로고
    • Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium
    • DZ Chen, M Qi, KJ Auborn, TH Carter: Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium. J Nutr 131, 3294-3302 (2001)
    • (2001) J Nutr , vol.131 , pp. 3294-3302
    • Chen, D.Z.1    Qi, M.2    Auborn, K.J.3    Carter, T.H.4
  • 241
    • 0038402729 scopus 로고    scopus 로고
    • Indole-3-carbinol and 3,3′-diindolylmethane induce apoptosis in human prostate cancer cells
    • M Nachshon-Kedmi, S Yannai, A Haj, FA Fares: Indole-3-carbinol and 3,3′-diindolylmethane induce apoptosis in human prostate cancer cells. Food Chem Toxicol 41, 745-752 (2003)
    • (2003) Food Chem Toxicol , vol.41 , pp. 745-752
    • Nachshon-Kedmi, M.1    Yannai, S.2    Haj, A.3    Fares, F.A.4
  • 242
    • 0042173140 scopus 로고    scopus 로고
    • A new indole-3-carbinol tetrameric derivative inhibits cyclindependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines
    • G Brandi, M Paiardini, B Cervasi, C Fiorucci, P Filippone, C De Marco, N Zaffaroni, M Magnani: A new indole-3-carbinol tetrameric derivative inhibits cyclindependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines. Cancer Res 63, 4028-4036 (2003)
    • (2003) Cancer Res , vol.63 , pp. 4028-4036
    • Brandi, G.1    Paiardini, M.2    Cervasi, B.3    Fiorucci, C.4    Filippone, P.5    De Marco, C.6    Zaffaroni, N.7    Magnani, M.8
  • 243
    • 0037662260 scopus 로고    scopus 로고
    • Indole-3-carbinol and 3-3′-diindolylmethane antiproliferative signaling pathways control cell-cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions
    • GL Firestone, LF Bjeldanes: Indole-3-carbinol and 3-3′- diindolylmethane antiproliferative signaling pathways control cell-cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions. J Nutr 133 (7 Suppl.), 2448S-255S (2003)
    • (2003) J Nutr , vol.133 , Issue.7 SUPPL.
    • Firestone, G.L.1    Bjeldanes, L.F.2
  • 244
    • 76749161020 scopus 로고    scopus 로고
    • Indole-3-carbinol induces apoptosis through p53 and activation of caspase-8 pathway in lung cancer A549 cells
    • HS Choi, MC Cho, HG Lee, DY Yoon: Indole-3-carbinol induces apoptosis through p53 and activation of caspase-8 pathway in lung cancer A549 cells. Food Chem Toxicol 48(3), 883-890 (2010)
    • (2010) Food Chem Toxicol , vol.48 , Issue.3 , pp. 883-890
    • Choi, H.S.1    Cho, M.C.2    Lee, H.G.3    Yoon, D.Y.4
  • 245
    • 3042642131 scopus 로고    scopus 로고
    • Inactivation of Akt and NF-kappaB play important roles during indole-3-carbinol-induced apoptosis in breast cancer cells
    • KW Rahman, Y Li, FH Sarkar: Inactivation of Akt and NF-kappaB play important roles during indole-3-carbinol-induced apoptosis in breast cancer cells. Nutr Cancer 48, 84-94 (2004)
    • (2004) Nutr Cancer , vol.48 , pp. 84-94
    • Rahman, K.W.1    Li, Y.2    Sarkar, F.H.3
  • 246
    • 77953784229 scopus 로고    scopus 로고
    • Direct inhibition of elastase activity by indole-3-carbinol triggers a CD40-TRAF regulatory cascade that disrupts NF-kappaB transcriptional activity in human breast cancer cells
    • I Aronchik, LF Bjeldanes, GL Firestone: Direct inhibition of elastase activity by indole-3-carbinol triggers a CD40-TRAF regulatory cascade that disrupts NF-kappaB transcriptional activity in human breast cancer cells. Cancer Res 70(12), 4961-4971 (2010)
    • (2010) Cancer Res , vol.70 , Issue.12 , pp. 4961-4971
    • Aronchik, I.1    Bjeldanes, L.F.2    Firestone, G.L.3
  • 247
    • 31544436372 scopus 로고    scopus 로고
    • Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells
    • CT Brew, I Aronchik, JC Hsu, JH Sheen, RB Dickson, LF Bjeldanes, GL Firestone: Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells. Int J Cancer 118(4), 857-868 (2006)
    • (2006) Int J Cancer , vol.118 , Issue.4 , pp. 857-868
    • Brew, C.T.1    Aronchik, I.2    Hsu, J.C.3    Sheen, J.H.4    Dickson, R.B.5    Bjeldanes, L.F.6    Firestone, G.L.7
  • 248
    • 0034531726 scopus 로고    scopus 로고
    • Indole-3-carbinol is a negative regulator of estrogen receptor-alpha signaling in human tumor cells
    • Q Meng, F Yuan, ID Goldberg, EM Rosen, K Auborn, S Fan: Indole-3-carbinol is a negative regulator of estrogen receptor-alpha signaling in human tumor cells. J Nutr 130, 2927-2931 (2000)
    • (2000) J Nutr , vol.130 , pp. 2927-2931
    • Meng, Q.1    Yuan, F.2    Goldberg, I.D.3    Rosen, E.M.4    Auborn, K.5    Fan, S.6
  • 249
    • 0035527492 scopus 로고    scopus 로고
    • Abrogation of estrogen-mediated cellular and biochemical effects by indole-3-carbinol
    • BT Ashok, Y Chen, X Liu, HL Bradlow, A Mittelman, RK Tiwari: Abrogation of estrogen-mediated cellular and biochemical effects by indole-3-carbinol. Nutr Cancer 41, 180-187 (2001)
    • (2001) Nutr Cancer , vol.41 , pp. 180-187
    • Ashok, B.T.1    Chen, Y.2    Liu, X.3    Bradlow, H.L.4    Mittelman, A.5    Tiwari, R.K.6
  • 250
    • 33751544458 scopus 로고    scopus 로고
    • Indole-3-carbinol selectively uncouples expression and activity of estrogen receptor subtypes in human breast cancer cells
    • SN Sundar, V Kerekatte, CN Equinozio, VB Doan, LF Bjeldanes, GL Firestone: Indole-3-carbinol selectively uncouples expression and activity of estrogen receptor subtypes in human breast cancer cells. Mol Endocrinol 20(12), 3070-3082 (2006)
    • (2006) Mol Endocrinol , vol.20 , Issue.12 , pp. 3070-3082
    • Sundar, S.N.1    Kerekatte, V.2    Equinozio, C.N.3    Doan, V.B.4    Bjeldanes, L.F.5    Firestone, G.L.6
  • 251
    • 0344844481 scopus 로고    scopus 로고
    • Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells
    • J Zhang, B A JC Hsu, B A MA Kinseth, LF Bjeldanes, GL Firestone: Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells. Cancer 98(11), 2511-2520 (2003)
    • (2003) Cancer , vol.98 , Issue.11 , pp. 2511-2520
    • Zhang, J.1    Hsu, J.C.2    Kinseth, M.A.3    Bjeldanes, L.F.4    Firestone, G.L.5
  • 252
    • 27744484361 scopus 로고    scopus 로고
    • Indole-3-carbinol inhibition of androgen receptor expression and downregulation of androgen responsiveness in human prostate cancer cells
    • JC Hsu, J Zhang, A Dev, A Wing, LF Bjeldanes, GL Firestone: Indole-3-carbinol inhibition of androgen receptor expression and downregulation of androgen responsiveness in human prostate cancer cells. Carcinogenesis 26(11), 1896-1904 (2005)
    • (2005) Carcinogenesis , vol.26 , Issue.11 , pp. 1896-1904
    • Hsu, J.C.1    Zhang, J.2    Dev, A.3    Wing, A.4    Bjeldanes, L.F.5    Firestone, G.L.6
  • 253
    • 77950667476 scopus 로고    scopus 로고
    • Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER) alpha protein degradation in breast cancer cells disrupting an ERalpha-GATA3 transcriptional cross-regulatory loop
    • CN Marconett, SN Sundar, KM Poindexter, TR Stueve, LF Bjeldanes, GL Firestone: Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER) alpha protein degradation in breast cancer cells disrupting an ERalpha-GATA3 transcriptional cross-regulatory loop. Mol Biol Cell 21(7), 1166-1177 (2010)
    • (2010) Mol Biol Cell , vol.21 , Issue.7 , pp. 1166-1177
    • Marconett, C.N.1    Sundar, S.N.2    Poindexter, K.M.3    Stueve, T.R.4    Bjeldanes, L.F.5    Firestone, G.L.6
  • 254
    • 59849109215 scopus 로고    scopus 로고
    • Indole-3-carbinol inhibits Sp1-induced matrix metalloproteinase-2 expression to attenuate migration and invasion of breast cancer cells
    • WC Hung, HC Chang: Indole-3-carbinol inhibits Sp1-induced matrix metalloproteinase-2 expression to attenuate migration and invasion of breast cancer cells. J Agric Food Chem 57(1), 76-82 (2009)
    • (2009) J Agric Food Chem , vol.57 , Issue.1 , pp. 76-82
    • Hung, W.C.1    Chang, H.C.2
  • 255
    • 0037469098 scopus 로고    scopus 로고
    • Modulation of vinca-alkaloid induced P-glycoprotein expression by indole-3-carbinol
    • A Arora, Y Shukla: Modulation of vinca-alkaloid induced P-glycoprotein expression by indole-3-carbinol. Cancer Lett. 189, 167-173 (2003)
    • (2003) Cancer Lett. , vol.189 , pp. 167-173
    • Arora, A.1    Shukla, Y.2
  • 256
    • 0030041159 scopus 로고    scopus 로고
    • Reversal of multidrug resistance in vivo by dietary administration of the phytochemical indole-3-carbinol
    • JG Christensen, GA LeBlanc: Reversal of multidrug resistance in vivo by dietary administration of the phytochemical indole-3-carbinol. Cancer Res 56, 574-581 (1996)
    • (1996) Cancer Res , vol.56 , pp. 574-581
    • Christensen, J.G.1    Leblanc, G.A.2
  • 257
    • 0033567096 scopus 로고    scopus 로고
    • Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice
    • L Jin, M Qi, DZ Chen, A Anderson, GY Yang, JM Arbeit, KJ Auborn: Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice. Cancer Res 59(16), 3991-3997 (1999)
    • (1999) Cancer Res , vol.59 , Issue.16 , pp. 3991-3997
    • Jin, L.1    Qi, M.2    Chen, D.Z.3    Anderson, A.4    Yang, G.Y.5    Arbeit, J.M.6    Auborn, K.J.7
  • 258
    • 48349127559 scopus 로고    scopus 로고
    • Review: Indole-3-carbinol as a chemoprotective agent in breast and prostate cancer
    • HL Bradlow: Review: Indole-3-carbinol as a chemoprotective agent in breast and prostate cancer. In vivo 22(4), 441-445 (2008)
    • (2008) In Vivo , vol.22 , Issue.4 , pp. 441-445
    • Bradlow, H.L.1
  • 260
    • 41149086283 scopus 로고    scopus 로고
    • Protective effects of isothiocyanates alone or in combination with vitamin C towards N-nitrosodibutylamine or Nnitrosopiperidine-induced oxidative DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay
    • A García, AI Haza, N Arranz, J Rafter, P Morales: Protective effects of isothiocyanates alone or in combination with vitamin C towards N-nitrosodibutylamine or Nnitrosopiperidine-induced oxidative DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. J Appl Toxicol 28(2), 196-204 (2008)
    • (2008) J Appl Toxicol , vol.28 , Issue.2 , pp. 196-204
    • García, A.1    Haza, A.I.2    Arranz, N.3    Rafter, J.4    Morales, P.5
  • 261
    • 33646530484 scopus 로고    scopus 로고
    • Indole-3-carbinol prevents PTEN loss in cervical cancer in vivo
    • M Qi, AE Anderson, DZ Chen, S Sun, KJ Auborn: Indole-3-carbinol prevents PTEN loss in cervical cancer in vivo. Mol Med 11(1-12), 59-63 (2005)
    • (2005) Mol Med , vol.11 , Issue.1-12 , pp. 59-63
    • Qi, M.1    Anderson, A.E.2    Chen, D.Z.3    Sun, S.4    Auborn, K.J.5
  • 262
    • 0036685480 scopus 로고    scopus 로고
    • Modulations of P450 mRNA in liver and mammary gland and P450 activities and metabolism of estrogen in liver by treatment of rats with indole-3-carbinol
    • TL Horn, MA Reichert, RL Bliss, D Malejka-Giganti: Modulations of P450 mRNA in liver and mammary gland and P450 activities and metabolism of estrogen in liver by treatment of rats with indole-3-carbinol. Biochem Pharmacol 64(3), 393-404 (2002)
    • (2002) Biochem Pharmacol , vol.64 , Issue.3 , pp. 393-404
    • Horn, T.L.1    Reichert, M.2    Bliss, R.L.3    Malejka-Giganti, D.4
  • 263
    • 62349095729 scopus 로고    scopus 로고
    • Dose-dependent inhibition of tobacco smoke carcinogeninduced lung tumorigenesis in A/J mice by indole-3-carbinol
    • F Kassie, I Matise, M Negia, P Upadhyaya, SS Hecht: Dose-dependent inhibition of tobacco smoke carcinogeninduced lung tumorigenesis in A/J mice by indole-3-carbinol. Cancer Prev Res (Phila Pa) 1(7), 568-576 (2008)
    • (2008) Cancer Prev Res (Phila Pa , vol.1 , Issue.7 , pp. 568-576
    • Kassie, F.1    Matise, I.2    Negia, M.3    Upadhyaya, P.4    Hecht, S.S.5
  • 264
    • 77649198519 scopus 로고    scopus 로고
    • Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myoinositol in A/J mice
    • F Kassie, S Kalscheuer, I Matise, L Ma, T Melkamu, P Upadhyaya, SS Hecht: Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myoinositol in A/J mice. Carcinogenesis 31(2), 239-245 (2010)
    • (2010) Carcinogenesis , vol.31 , Issue.2 , pp. 239-245
    • Kassie, F.1    Kalscheuer, S.2    Matise, I.3    Ma, L.4    Melkamu, T.5    Upadhyaya, P.6    Hecht, S.S.7
  • 265
    • 37349014596 scopus 로고    scopus 로고
    • Effects of prepubertal indole-3-carbinol treatment on development of N-methyl-N-nitrosourea-induced mammary carcinomas in female Sprague-Dawley rats
    • N Shimano, N Uehara, Y Kiyozuka, N Shikata, A Tsubura: Effects of prepubertal indole-3-carbinol treatment on development of N-methyl-N- nitrosourea-induced mammary carcinomas in female Sprague-Dawley rats. In vivo 21(6), 983-988 (2007)
    • (2007) In Vivo , vol.21 , Issue.6 , pp. 983-988
    • Shimano, N.1    Uehara, N.2    Kiyozuka, Y.3    Shikata, N.4    Tsubura, A.5
  • 266
    • 33750541268 scopus 로고    scopus 로고
    • Down-regulation of androgen receptor by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells
    • MM Bhuiyan, Y Li, S Banerjee, F Ahmed, Z Wang, S Ali, FH Sarkar: Down-regulation of androgen receptor by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells. Cancer Res 66(20), 10064-10072 (2006)
    • (2006) Cancer Res , vol.66 , Issue.20 , pp. 10064-10072
    • Bhuiyan, M.M.1    Li, Y.2    Banerjee, S.3    Ahmed, F.4    Wang, Z.5    Ali, S.6    Sarkar, F.H.7
  • 267
    • 34547135737 scopus 로고    scopus 로고
    • Regulation of FOXO3a/betacatenin/GSK-3beta signaling by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cancer cells
    • Y Li, Z Wang, D Kong, S Murthy, QP Dou, S Sheng, GP Reddy, FH Sarkar: Regulation of FOXO3a/betacatenin/GSK-3beta signaling by 3,3′- diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cancer cells. J Biol Chem 282(29), 21542-21550 (2007)
    • (2007) J Biol Chem , vol.282 , Issue.29 , pp. 21542-21550
    • Li, Y.1    Wang, Z.2    Kong, D.3    Murthy, S.4    Dou, Q.P.5    Sheng, S.6    Reddy, G.P.7    Sarkar, F.H.8
  • 268
    • 0031715037 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane
    • I Chen, A McDougal, F Wang, S Safe: Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane. Carcinogenesis 19(9), 1631-1639 (1998)
    • (1998) Carcinogenesis , vol.19 , Issue.9 , pp. 1631-1639
    • Chen, I.1    McDougal, A.2    Wang, F.3    Safe, S.4
  • 269
    • 33845964968 scopus 로고    scopus 로고
    • Activation of caspase-8 contributes to 3,3′-Diindolylmethane- induced apoptosis in colon cancer cells
    • EJ Kim, SY Park, HK Shin, DY Kwon, YJ Surh, JH Park: Activation of caspase-8 contributes to 3,3′-Diindolylmethane-induced apoptosis in colon cancer cells. J Nutr 137(1), 31-36 (2007)
    • (2007) J Nutr , vol.137 , Issue.1 , pp. 31-36
    • Kim, E.J.1    Park, S.Y.2    Shin, H.K.3    Kwon, D.Y.4    Surh, Y.J.5    Park, J.H.6
  • 270
    • 29644444307 scopus 로고    scopus 로고
    • 3,3′-Diindolylmethane downregulates pro-survival pathway in hormone independent prostate cancer
    • VP Garikapaty, BT Ashok, K Tadi, A Mittelman, RK Tiwari: 3,3′-Diindolylmethane downregulates pro-survival pathway in hormone independent prostate cancer. Biochem Biophys Res Commun 340(2), 718-725 (2006)
    • (2006) Biochem Biophys Res Commun , vol.340 , Issue.2 , pp. 718-725
    • Garikapaty, V.P.1    Ashok, B.T.2    Tadi, K.3    Mittelman, A.4    Tiwari, R.K.5
  • 272
    • 12844249890 scopus 로고    scopus 로고
    • Identification of estrogen receptor alpha as a gene down regulated by indole-3-carbinol in human breast cancer cell MCF-7: A cDNA microarray approach
    • Oct 14-18, 2002, Boston MA
    • TTY Wang, MJ Milner, YS Kim: Identification of estrogen receptor alpha as a gene down regulated by indole-3-carbinol in human breast cancer cell MCF-7: a cDNA microarray approach. Proceedings; Frontier in Cancer Prevention Research (Oct 14-18, 2002, Boston MA), 150 (2002)
    • (2002) Proceedings; Frontier in Cancer Prevention Research , vol.150
    • Wang, T.T.Y.1    Milner, M.J.2    Kim, Y.S.3
  • 274
    • 0842334473 scopus 로고    scopus 로고
    • Potent ligand-independent estrogen receptor activation by 3,3′-di-indolylmethane is mediated by cross talk between the protein kinase A and mitogen-activated protein kinase signaling pathways
    • H Leong, JE Riby, GL Firestone, LF Bjeldanes: Potent ligand-independent estrogen receptor activation by 3,3′-di-indolylmethane is mediated by cross talk between the protein kinase A and mitogen-activated protein kinase signaling pathways. Mol Endocrinol 18, 291-302 (2004)
    • (2004) Mol Endocrinol , vol.18 , pp. 291-302
    • Leong, H.1    Riby, J.E.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 275
    • 0035161486 scopus 로고    scopus 로고
    • Cytostatic effects of 3,3′-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-alpha expression
    • H Leong, GL Firestone, LF Bjeldanes: Cytostatic effects of 3,3′-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-alpha expression. Carcinogenesis 22, 1809-1817 (2001)
    • (2001) Carcinogenesis , vol.22 , pp. 1809-1817
    • Leong, H.1    Firestone, G.L.2    Bjeldanes, L.F.3
  • 276
    • 35948988561 scopus 로고    scopus 로고
    • Inactivation of NFkappaB by 3,3′-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells
    • KM Rahman, S Ali, A Aboukameel, SH Sarkar, Z Wang, PA Philip, WA Sakr, A Raz: Inactivation of NFkappaB by 3,3′-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells. Mol Cancer Ther 6(10), 2757-2765 (2007)
    • (2007) Mol Cancer Ther , vol.6 , Issue.10 , pp. 2757-2765
    • Rahman, K.M.1    Ali, S.2    Aboukameel, A.3    Sarkar, S.H.4    Wang, Z.5    Philip, P.A.6    Sakr, W.A.7    Raz, A.8
  • 277
    • 17844381889 scopus 로고    scopus 로고
    • 3,3′-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice
    • X Chang, JC Tou, C Hong, HA Kim, JE Riby, GL Firestone, LF Bjeldanes: 3,3′-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice. Carcinogenesis 26(4), 771-778 (2005)
    • (2005) Carcinogenesis , vol.26 , Issue.4 , pp. 771-778
    • Chang, X.1    Tou, J.C.2    Hong, C.3    Kim, H.A.4    Riby, J.E.5    Firestone, G.L.6    Bjeldanes, L.F.7
  • 278
    • 72249116503 scopus 로고    scopus 로고
    • Oral administration of 3,3′-diindolylmethane inhibits lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice
    • EJ Kim, M Shin, H Park, JE Hong, HK Shin, J Kim, DY Kwon, JH Park: Oral administration of 3,3′-diindolylmethane inhibits lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice. J Nutr 139(12), 2373-2379 (2009)
    • (2009) J Nutr , vol.139 , Issue.12 , pp. 2373-2379
    • Kim, E.J.1    Shin, M.2    Park, H.3    Hong, J.E.4    Shin, H.K.5    Kim, J.6    Kwon, D.Y.7    Park, J.H.8
  • 279
    • 0021073686 scopus 로고
    • Protective effect of citrus fruit on esophageal cancer
    • AJ Tuyns: Protective effect of citrus fruit on esophageal cancer. Nutrition and Cancer 5, 195-200 (1983)
    • (1983) Nutrition and Cancer , vol.5 , pp. 195-200
    • Tuyns, A.J.1
  • 281
    • 0031960393 scopus 로고    scopus 로고
    • Diet and squamous-cell cancer of the oesophagus: A French multicentre case-control study
    • G Launoy, C Milan, NE Day, MP Pienkowski, M Gignoux, J Faivre: Diet and squamous-cell cancer of the oesophagus: a French multicentre case-control study. Int J Cancer 76(1), 7-12. (1998)
    • (1998) Int J Cancer , vol.76 , Issue.1 , pp. 7-12
    • Launoy, G.1    Milan, C.2    Day, N.E.3    Pienkowski, M.P.4    Gignoux, M.5    Faivre, J.6
  • 282
    • 0033637602 scopus 로고    scopus 로고
    • Citrus peel use is associated with reduced risk of squamous cell carcinoma of the skin
    • IA Hakim, RB Harris, C Ritenbaugh. Citrus peel use is associated with reduced risk of squamous cell carcinoma of the skin. Nutr Cancer 37(2), 161-168 (2000)
    • (2000) Nutr Cancer , vol.37 , Issue.2 , pp. 161-168
    • Hakim, I.A.1    Harris, R.B.2    Ritenbaugh, C.3
  • 283
    • 0035729956 scopus 로고    scopus 로고
    • Differential inhibition of human cancer cell proliferation by citrus limonoids
    • Q Tian, EG Miller, H Ahmad, L Tang, BS Patil: Differential inhibition of human cancer cell proliferation by citrus limonoids. Nutr Cancer 40(2), 180-184 (2001)
    • (2001) Nutr Cancer , vol.40 , Issue.2 , pp. 180-184
    • Tian, Q.1    Miller, E.G.2    Ahmad, H.3    Tang, L.4    Patil, B.S.5
  • 284
    • 0032980875 scopus 로고    scopus 로고
    • Prevention and therapy of cancer by dietary monoterpenes
    • PL Crowell: Prevention and therapy of cancer by dietary monoterpenes. J Nutr: 129,775S-778S (1999)
    • (1999) J Nutr , vol.129
    • Crowell, P.L.1
  • 285
    • 0032905653 scopus 로고    scopus 로고
    • Inhibition by dlimonene of gastric carcinogenesis induced by N-methyl-N'-nitro-Nnitrosoguanidine in Wistar rats
    • N Uedo, M Tatsuta, H Iishi, et al: Inhibition by dlimonene of gastric carcinogenesis induced by N-methyl-N'-nitro-Nnitrosoguanidine in Wistar rats. Cancer Lett 137,131-136 (1999)
    • (1999) Cancer Lett , vol.137 , pp. 131-136
    • Uedo, N.1    Tatsuta, M.2    Iishi, H.3
  • 286
    • 0033609728 scopus 로고    scopus 로고
    • Attenuation by dlimonene of sodium chloride-enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats
    • H Yano, M Tatsuta, H Iishi, et al: Attenuation by dlimonene of sodium chloride-enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N- nitrosoguanidine in Wistar rats. Int J Cancer 82,665-668 (1999)
    • (1999) Int J Cancer , vol.82 , pp. 665-668
    • Yano, H.1    Tatsuta, M.2    Iishi, H.3
  • 287
    • 2442497423 scopus 로고    scopus 로고
    • Effects of dietary anticarcinogens and nonsteroidal anti-inflammatory drugs on rat gastrointestinal UDP-glucuronosyltransferases
    • EM Van der Logt, HM Roelofs, EM van Lieshout, FM Nagengast, WH Peters: Effects of dietary anticarcinogens and nonsteroidal anti-inflammatory drugs on rat gastrointestinal UDP-glucuronosyltransferases. Anticancer Res 24(B), 843-849 (2004)
    • (2004) Anticancer Res , vol.2 , Issue.B , pp. 843-849
    • Logt Der E.Van1    Roelofs, H.M.2    Van Lieshout, E.M.3    Nagengast, F.M.4    Peters, W.H.5
  • 290
    • 0023870472 scopus 로고
    • Anti-carcinogenic activity of d-limonene during the initiation and promotion/progression stages of DMBA-induced rat mammary carcinogenesis
    • CE Elson, TH Maltzman, JL Boston, MA Tanner, MN Gould: Anti-carcinogenic activity of d-limonene during the initiation and promotion/progression stages of DMBA-induced rat mammary carcinogenesis. Carcinogenesis 9,331-332 (1988)
    • (1988) Carcinogenesis , vol.9 , pp. 331-332
    • Elson, C.E.1    Maltzman, T.H.2    Boston, J.L.3    Tanner, M.4    Gould, M.N.5
  • 291
    • 0024519869 scopus 로고
    • The prevention of nitrosomethylurea-induced mammary tumors by d-limonene and orange oil
    • TH Maltzman, LM Hurt, CE Elson, MA Tanner, MN Gould: The prevention of nitrosomethylurea-induced mammary tumors by d-limonene and orange oil. Carcinogenesis 10, 781-783 (1989)
    • (1989) Carcinogenesis , vol.10 , pp. 781-783
    • Maltzman, T.H.1    Hurt, L.M.2    Elson, C.E.3    Tanner, M.4    Gould, M.N.5
  • 292
    • 0020587373 scopus 로고
    • Inhibition of neoplasia by minor dietary constituents
    • LW Wattenberg: Inhibition of neoplasia by minor dietary constituents. Cancer Res 43, 2448S-2453S (1983)
    • (1983) Cancer Res , vol.43
    • Wattenberg, L.W.1
  • 294
    • 0025933489 scopus 로고
    • The presence of alpha 2uglobulin is necessary for d-limonene promotion of male rat kidney tumors
    • DR Dietrich, JA Swenberg: The presence of alpha 2uglobulin is necessary for d-limonene promotion of male rat kidney tumors. Cancer Res 51, 3512-3521 (1991)
    • (1991) Cancer Res , vol.51 , pp. 3512-3521
    • Dietrich, D.R.1    Swenberg, J.A.2
  • 295
    • 0024378052 scopus 로고
    • Inhibition of N-nitrosodiethylamine carcinogenesis in mice by naturally occurring organosulfur compounds and monoterpenes
    • LW Wattenberg, VL Sparnins, G Barany: Inhibition of N-nitrosodiethylamine carcinogenesis in mice by naturally occurring organosulfur compounds and monoterpenes. Cancer Res 49, 2689-2692 (1989)
    • (1989) Cancer Res , vol.49 , pp. 2689-2692
    • Wattenberg, L.W.1    Sparnins, V.L.2    Barany, G.3
  • 296
    • 0025975780 scopus 로고
    • Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone carcinogenesis in mice by d-limonene and citrus fruit oils
    • 296
    • LW Wattenberg, JB Coccia: Inhibition of 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone carcinogenesis in mice by d-limonene and citrus fruit oils. Carcinogenesis 12, 115-117 (1991) 296.
    • (1991) Carcinogenesis , vol.12 , pp. 115-117
    • Wattenberg, L.W.1    Coccia, J.B.2
  • 297
    • 0028229474 scopus 로고
    • Limonene chemoprevention of mammary carcinoma induction following direct in situ transfer of v-Ha-ras
    • MN Gould, CJ Moore, R Zhang, B Wang, WS Kennan, JD Haag: Limonene chemoprevention of mammary carcinoma induction following direct in situ transfer of v-Ha-ras. Cancer Res 54, 3540-3543 (1994)
    • (1994) Cancer Res , vol.54 , pp. 3540-3543
    • Gould, M.N.1    Moore, C.J.2    Zhang, R.3    Wang, B.4    Kennan, W.S.5    Haag, J.D.6
  • 298
    • 0030011886 scopus 로고    scopus 로고
    • Inhibitory effects of d-limonene on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats
    • T Kawamori, T Tanaka, Y Hirose, M Ohnishi, H Mori: Inhibitory effects of d-limonene on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats. Carcinogenesis 17, 369-372 (1996)
    • (1996) Carcinogenesis , vol.17 , pp. 369-372
    • Kawamori, T.1    Tanaka, T.2    Hirose, Y.3    Ohnishi, M.4    Mori, H.5
  • 300
    • 0016430368 scopus 로고
    • Studies on the metabolism of d-Limonene (p-Mentha-1,8-diene III. Effects of d-Limonene on the lipids and drugmetabolizing enzymes in rat livers
    • T Ariyoshi, M Arakaki, K Ideguchi, Y Ishizuka, K Noda: Studies on the metabolism of d-Limonene (p-Mentha-1,8-diene). III. Effects of d-Limonene on the lipids and drugmetabolizing enzymes in rat livers. Xenobiotica 5(1), 33-38 (1975)
    • (1975) Xenobiotica , vol.5 , Issue.1 , pp. 33-38
    • Ariyoshi, T.1    Arakaki, M.2    Ideguchi, K.3    Ishizuka, Y.4    Noda, K.5
  • 301
    • 0025948240 scopus 로고
    • Effects of monoterpenoids on in vivo DMBA-DNA adduct formation and on phase i hepatic metabolizing enzymes
    • TH Maltzman, M Christou, MN Gould, CR Jefcoate: Effects of monoterpenoids on in vivo DMBA-DNA adduct formation and on phase I hepatic metabolizing enzymes. Carcinogenesis 12(11), 2081-2087 (1991)
    • (1991) Carcinogenesis , vol.12 , Issue.11 , pp. 2081-2087
    • Maltzman, T.H.1    Christou, M.2    Gould, M.N.3    Jefcoate, C.R.4
  • 302
    • 0033194729 scopus 로고    scopus 로고
    • D-limonene chemoprevention of hepatocarcinogenesis in AKR mice: Inhibition of c-jun and c-myc
    • RK Giri, T Parija, BR Das: D-limonene chemoprevention of hepatocarcinogenesis in AKR mice: inhibition of c-jun and c-myc. Oncol Rep 6, 1123-1127 (1999)
    • (1999) Oncol Rep , vol.6 , pp. 1123-1127
    • Giri, R.K.1    Parija, T.2    Das, B.R.3
  • 303
    • 0035427196 scopus 로고    scopus 로고
    • Inhibition by d-limonene of experimental hepatocarcinogenesis in Sprague-Dawley rats does not involve p21(ras) plasma membrane association
    • I Kaji, M Tatsuta, H Iishi, M Baba, A Inoue, H Kasugai: Inhibition by d-limonene of experimental hepatocarcinogenesis in Sprague-Dawley rats does not involve p21(ras) plasma membrane association. Int J Cancer 93, 441-444 (2001)
    • (2001) Int J Cancer , vol.93 , pp. 441-444
    • Kaji, I.1    Tatsuta, M.2    Iishi, H.3    Baba, M.4    Inoue, A.5    Kasugai, H.6
  • 304
    • 84883385806 scopus 로고    scopus 로고
    • Norman: University of Oklahoma Press
    • Norman: University of Oklahoma Press.Nunn J. Ancient Egyptian medicine p. 1-240 (1996)
    • (1996) Nunn J. Ancient Egyptian Medicine , pp. 1-240
  • 305
    • 0001502075 scopus 로고
    • Tumor inhibition by a sulfhydryl-blocking agent related to an active principle of garlic (Allium sativum)
    • AS Weisberger, J Pensky: Tumor inhibition by a sulfhydryl-blocking agent related to an active principle of garlic (Allium sativum). Cancer Res18, 1301-1308 (1958)
    • (1958) Cancer Res , vol.18 , pp. 1301-1308
    • Weisberger, A.S.1    Pensky, J.2
  • 307
    • 0027462434 scopus 로고
    • Garlic and its significance for the prevention of cancer in humans: A critical review
    • E Dorant, PA van den Brandt, RA Goldbohm, RJ Hermus, F Sturmans: Garlic and its significance for the prevention of cancer in humans: a critical review. Br J Cancer 67, 424-429 (1993)
    • (1993) Br J Cancer , vol.67 , pp. 424-429
    • Dorant, E.1    Brandt Den P.Van2    Goldbohm, R.A.3    Hermus, R.J.4    Sturmans, F.5
  • 310
    • 0035126524 scopus 로고    scopus 로고
    • Antiproliferative effects of allium derivatives from garlic
    • JT Pinto, RS Rivlin: Antiproliferative effects of allium derivatives from garlic. J Nutr 131, 1058S-1060S (2001)
    • (2001) J Nutr , vol.131
    • Pinto, J.T.1    Rivlin, R.S.2
  • 311
    • 0035732772 scopus 로고    scopus 로고
    • Relative activities of organosulfur compounds derived from onions and garlic in increasing tissue activities of quinine reductase and glutathione transferase in rat tissues
    • R Munday, CM Munday: Relative activities of organosulfur compounds derived from onions and garlic in increasing tissue activities of quinine reductase and glutathione transferase in rat tissues. Nutr Cancer 40, 205-210 (2001)
    • (2001) Nutr Cancer , vol.40 , pp. 205-210
    • Munday, R.1    Munday, C.M.2
  • 314
    • 0029859071 scopus 로고    scopus 로고
    • Chemoprevention of mammary cancer by diallyl selenide, a novel organoselenium compound
    • K El-Bayoumy, Y Chae, P Upadhyaya, C Ip: Chemoprevention of mammary cancer by diallyl selenide, a novel organoselenium compound. Anticancer Res 16, 2911-2915 (1996)
    • (1996) Anticancer Res , vol.16 , pp. 2911-2915
    • El-Bayoumy, K.1    Chae, Y.2    Upadhyaya, P.3    Ip, C.4
  • 315
    • 0028061908 scopus 로고
    • Evaluation of chemopreventive agents against breast cancer and proposed strategies for future clinical intervention trials
    • K EI-Bayoumy: Evaluation of chemopreventive agents against breast cancer and proposed strategies for future clinical intervention trials. Carcinogenesis 15, 2395-2420 (1994)
    • (1994) Carcinogenesis , vol.15 , pp. 2395-2420
    • Ei-Bayoumy, K.1
  • 316
    • 0025030412 scopus 로고
    • Chemoprevention of 1,2-dimethylhydrazine-induced colon cancer in mice by naturally occurring organosulfur compounds
    • H Sumiyoshi, MJ Wargovich: Chemoprevention of 1,2-dimethylhydrazine- induced colon cancer in mice by naturally occurring organosulfur compounds. Cancer Res 50, 5084-5087 (1990)
    • (1990) Cancer Res , vol.50 , pp. 5084-5087
    • Sumiyoshi, H.1    Wargovich, M.J.2
  • 317
    • 0025760882 scopus 로고
    • Differential induction of glutathione transferase isoenzymes of mice stomach by diallyl sulfide, a naturally occurring anticarcinogen
    • AK Maurya, SV Singh: Differential induction of glutathione transferase isoenzymes of mice stomach by diallyl sulfide, a naturally occurring anticarcinogen. Cancer Lett 57, 121-129 (1991)
    • (1991) Cancer Lett , vol.57 , pp. 121-129
    • Maurya, A.K.1    Singh, S.V.2
  • 318
    • 0035126521 scopus 로고    scopus 로고
    • Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic
    • CS Yang, SK Chhabra, JY Hong, TJ Smith: Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic. J Nutr 131,1041s-1045s (2001)
    • (2001) J Nutr , vol.131
    • Yang, C.S.1    Chhabra, S.K.2    Hong, J.Y.3    Smith, T.J.4
  • 319
    • 77950280661 scopus 로고    scopus 로고
    • Diallyl trisulfide inhibits phorbol ester-induced tumor promotion, activation of AP-1, and expression of COX-2 in mouse skin by blocking JNK and Akt signaling
    • S Shrotriya, JK Kundu, HK Na, YJ Surh: Diallyl trisulfide inhibits phorbol ester-induced tumor promotion, activation of AP-1, and expression of COX-2 in mouse skin by blocking JNK and Akt signaling. Cancer Res 70(5), 1932-1940 (2010)
    • (2010) Cancer Res , vol.70 , Issue.5 , pp. 1932-1940
    • Shrotriya, S.1    Kundu, J.K.2    Na, H.K.3    Surh, Y.J.4
  • 320
    • 0023739534 scopus 로고
    • Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione Stransferase activity in the mouse
    • VL Sparnins, G Barany, LW Wattenberg: Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione Stransferase activity in the mouse. Carcinogenesis 9(1), 131-134 (1988)
    • (1988) Carcinogenesis , vol.9 , Issue.1 , pp. 131-134
    • Sparnins, V.L.1    Barany, G.2    Wattenberg, L.W.3
  • 321
    • 0024273970 scopus 로고
    • Chemoprevention of N-nitrosomethylbenzylamineinduced esophageal cancer in rats by the naturally occurring thieother, diallyl sulfide
    • MJ Wargovich, C Woods, VW Eng, LC Stephens, K Gray: Chemoprevention of N-nitrosomethylbenzylamineinduced esophageal cancer in rats by the naturally occurring thieother, diallyl sulfide. Cancer Res 48, 6872-6875 (1988)
    • (1988) Cancer Res , vol.48 , pp. 6872-6875
    • Wargovich, M.J.1    Woods, C.2    Eng, V.W.3    Stephens, L.C.4    Gray, K.5
  • 322
    • 0023221785 scopus 로고
    • Diallyl sulfide, a flavor component of garlic (Allium sativum), inhibits dimethylhydrazine-induced colon cancer
    • MJ Wargovich: Diallyl sulfide, a flavor component of garlic (Allium sativum), inhibits dimethylhydrazine-induced colon cancer. Carcinogenesis 8,487-489 (1987)
    • (1987) Carcinogenesis , vol.8 , pp. 487-489
    • Wargovich, M.J.1
  • 323
    • 4143124756 scopus 로고    scopus 로고
    • Modulation of altered hepatic foci induction by diallyl sulphide in Wistar rats
    • A Singh, A Arora, Y Shukla: Modulation of altered hepatic foci induction by diallyl sulphide in Wistar rats. Eur J Cancer Prev 13(4), 263-269 (2004)
    • (2004) Eur J Cancer Prev , vol.13 , Issue.4 , pp. 263-269
    • Singh, A.1    Arora, A.2    Shukla, Y.3


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