Case-control study on beneficial effect of regular consumption of apples on colorectal cancer risk in a population with relatively low intake of fruits and vegetables

European Journal of Cancer Prevention

Volumn 19, Issue 1, 2010, Pages 42-47

  Jedrychowski, Wieslaw ^a   Maugeri, Umberto ^b   Popiela, Tadeusz ^a   Kulig, Jan ^a   Sochacka Tatara, Elzbieta ^a   Pac, Agnieszka ^a   Sowa, Agata ^a   Musial, Agnieszka ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b IRCCS   (Italy)

Author keywords

Apple consumption; Case control study; Colorectal cancer risk

Indexed keywords

FLAVONOID; POLYPHENOL;

ADULT; AGED; APPLE; ARTICLE; CANCER INHIBITION; CANCER RISK; CASE CONTROL STUDY; CELL PROLIFERATION; COLORECTAL CANCER; CONTROLLED STUDY; DEMOGRAPHY; DIETARY INTAKE; FEMALE; FRUIT; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PRIORITY JOURNAL; RISK ASSESSMENT; SMOKING; VEGETABLE;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; EATING; FEEDING BEHAVIOR; FEMALE; FRUIT; HUMANS; MALE; MALUS; MIDDLE AGED; POPULATION; RISK FACTORS; VEGETABLES;

EID: 75149132767     PISSN: 09598278     EISSN: None     Source Type: Journal    
DOI: 10.1097/CEJ.0b013e328333d0cc     Document Type: Article

References (42)

1. Ames B, Shigenaga M, Hagen T (1993). Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci 90:7915-7922.
2. Arts IC, Jacobs DR Jr, Gross M, Harnack LJ, Folsom AR (2002). Dietary catechins and cancer incidence among postmenopausal women: the Iowa Women's Health Study (United States). Cancer Causes Control 13:373-382.
3. Block G, Patterson B, Subar A (1992). Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 18:1-29.
4. Bobe G, Sansbury LB, Albert PS, Cross AJ, Kahle L, Ashby J, et al. (2007). Dietary flavonoids and colorectal adenoma recurrence in the Polyp Prevention Trial. Cancer Epidemiol Biomarkers Prev 17:1344-1353.
5. Boyer J, Liu LH (2004). Apple phytochemicals and their health benefits. Nutr J 3 :5.
6. Butland B, Fehily A, Elwood P (2000). Diet, lung function, and lung decline in a cohort of 2512 middle aged men. Thorax 55:102-108.
7. De Oliviera M, Sichieri R, Moura A (2003).Weight loss associated with a daily intake of three apples or three pears among overweight women. Nutr 19:253-256.
8. Deneo-Pellegrini H, De Stefani E, Ronco A (1996). Vegetables, fruits, and risk of colorectal cancer. A case-control study from Uruguay. Nutr Cancer 25:297-304.
9. Doll R, Peto R (1981). The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. J Natl Cancer Inst 66:1191-1308.
10. Eberhardt M, Lee C, Liu RH (2000). Antioxidant activity of fresh apples. Nature 4 05:903-904.
11. Gallus C, Talamini R, Giacosa A, Montella M, Ramazzotti V, Franceschi S, et al. (2005). Does an apple a day keep the oncologist away? Ann Oncol 16: 1 841-1844.
12. Haenszel W, Kurihara M (1968). Studies of Japanese migrants. I. Mortality from cancer and other diseases among Japanese in the United States. J Natl Cancer Inst 40:43-68.
13. Hollman P, Katan M (1997). Absorption, metabolism and health effects of dietary flavonoids in man. Biomed Pharmacother 5:305-310.
14. Hollman PC, de Vries JH, van Leeuwen SD, Mengelers MJ, Katan MB (1995). Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers. Am J Clin Nutr 62:1276-1282.
15. Hollman PC, van Trijp JM, Buysman MN, van der Gaag MS, Mengelers MJ, de Vries JH, Katan MB (1997). Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man. FEBS Lett 418:152-156.
16. Hubbard G, Wolffram S, Lovegrove J, Gibbins JM (2003). The role of polyphenolic compounds in the diet as inhibitors of platelet function. Proc Nutr Soc 62:469-478.
17. Knekt P, Järvinen R, Reunanen A, Maatela J (1996). Flavonoid intake and coronary mortality in Finland: a cohort study. BMJ 312:478-481.
18. Knekt P, Isotupa S, Rissanen H, Heliö vaara M, Järvinen R, Häkkinen S, et al. (2000). Quercetin intake and the incidence of cerebrovascular disease. Eur Clin Nutr 54:415-417.
19. Knekt P, Kumpulainen J, Jarvinen R, Rissanen H, Heliö vaara M, Reunanen A, et al. (2002). Flavonoid intake and risk of chronic diseases. Am J Clin Nutr 7 6:560-568.
20. Koushik A, Hunter DJ, Spiegelman D, Beeson WL, van den Brandt PA, Buring JE, et al. (2007). Fruits, vegetables, and colon cancer risk in a pooled analysis of 1 4 cohort studies. J Natl Cancer Inst 99:1471-1483.
21. Kuhnau J (1976). The flavonoids. A class of semi-essential food components: their role in human nutrition. World Rev Nutr Diet 24:117-191.
22. La Vecchia C, Tavani A (1998). Fruit and vegetables, and human cancer. Eur J Cancer Prev 7:3-8.
23. Lee KW, Kim YJ, Kim DO, Lee HJ, Lee CY (2003). Major phenolics in apple and their contribution to the total antioxidant capacity. J Agric Food Chem 5 1:6516-6520.
24. Lee MJ,Wang ZY, Li H, Chen L, Sun Y, Gobbo S, et al. (1995). Analysis of plasma and urinary tea polyphenols in human subjects. Cancer Epidemiol Biomarkers Prev 4:393-399.
25. Lin J, Zhang SM,Wu K,Willett WC, Fuchs CS, Giovannucci E (2006). Flavonoid intake and colorectal cancer risk in men and women. Am J Epidemiol 1 64:644-651. (Pubitemid 44453493)
26. Manach C, Scalbert A, Morand C, Rémé sy C, Jimé nez L (2004). Polyphenols: food sources and bioavailability. Am J Clin Nutr 79:727-747.
27. Margetts BM, Pietinen P, Ribolo E (1997). EPIC European prospective investigation into cancer and nutrition. Validation studies on dietary assessment methods. Int J Epidemiol 26 (Suppl 1):1-189.
28. Ross JA, Kasum CM (2002). Dietary flavonoids: bioavailability, metabolic effects, and safety. Annu Rev Nutr 22:19-34.
29. Rossi M, Negri E, Talamini R, Bosetti C, Parpinel M, Gnagnarella P, et al. (2006). Flavonoids and colorectal cancer in Italy. Cancer Epidemiol Biomarkers Prev 1 5:1555-1558.
30. Sesso H, Gaziano JM, Liu S, Bering JE (2003). Flavonoid intake and risk of cardiovascular disease in women. Am J Clin Nutr 77:1400-1408. (Pubitemid 39655272)
31. Shaheen SO, Sterne JA, Thompson RL, Songhurst CE, Margetts BM, Burney PG (2001). Dietary antioxidants and asthma in adults-population based case-control study. Am J Respir Crit Care Med 164: 1 823-1828.
32. Spencer JP (2003). Metabolism of tea flavonoids in the gastrointestinal tract. J Nutr 133 (Suppl):3255S-3261S.
33. Sun J, Chu YF,Wu X, Liu RH (2002). Antioxidant and antiproliferative activities of common fruits. J Agric Food Chem 50:7449-7454. (Pubitemid 35424917)
34. Tabak C, Arts IC, Smit HA, Heederik D, Kromhout D (2001). Chronic obstructive pulmonary disease and intake of catechins, flavonols, and flavones: the Morgen Study. Am J Respir Crit Care Med 164:61-64.
35. Van der Sluis A, Dekker M, de Jager A, Jongen WM (2001). Activity and concentration of polyphenolic antioxidants in apple: effect of cultivar, harvest year, and storage conditions. J Agric Food Chern 49:3606-3613.
36. Vinson J, Su X, Zubik L, Bose P (2001). Phenol antioxidant quantity and quality in foods: fruits. J Agric Food Chem 49:5315-5321.
37. Wang L, Lee IM, Zhang SM, Blumberg JB, Buring JE, Sesso HD (2009). Dietary intake of selected flavonols, flavones, and flavonoid-rich foods and risk of cancer in middle-aged and older women. Am J Clin Nutr 89:905-912.
38. Willett W (1995). Diet, nutrition, and avoidable cancer. Environ Health Perspect 1 03:165-170.
39. Wolfe K, Liu RH (2003). Apple peels as a value-added food ingredient. J Agric Food Chern 51:1676-1683.
40. Wolfe K, Wu X, Liu RH (2003). Antioxidant activity of apple peels. J Agric Food Chem 51:609-614.
41. World Cancer Research Fund/American Institute for Cancer Research (2007). Food, nutrition, physical activity, and the prevention of cancer: a global perspective. Washington DC: AICR.
42. Yang CS, Landau JM, Huang MT, Newmark HL (2001). Inhibition of carcinogenesis by dietary polyphenolic compounds. Ann Rev Nutr 21:381-406.