Lower prostate cancer risk in men with elevated plasma lycopene levels: Results of a prospective analysis

Cancer Research

Volumn 59, Issue 6, 1999, Pages 1225-1230

  Gann, Peter H ^c   Ma, Jing ^a   Giovannucci, Edward ^a,b   Willett, Walter ^b   Sacks, Frank M ^b   Hennekens, Charles H ^a,b   Stampfer, Meir J ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CAROTENE; LYCOPENE;

ADULT; AGED; ARTICLE; CANCER PREVENTION; CANCER RISK; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC VALUE; DIET SUPPLEMENTATION; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROSTATE CANCER; TOMATO;

ADULT; AGED; AGED, 80 AND OVER; ANTIOXIDANTS; ASPIRIN; BETA CAROTENE; CAROTENOIDS; CASE-CONTROL STUDIES; COHORT STUDIES; DOUBLE-BLIND METHOD; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PROSTATIC NEOPLASMS; RANDOMIZED CONTROLLED TRIALS; RISK FACTORS;

EID: 0033559952     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Steinmetz, K. A., and Potter, J. D. Vegetables, fruit, and cancer. II. Mechanisms, Cancer Causes Control, 2: 427-442, 1991.
2. Kolonel, L. N. Nutrition and prostate cancer. Cancer Causes Control, 7: 83-94, 1996.
3. Giovannucci, E., Ascherio, A., Rimm, E. B., Stampfer, M. J., Colditz, O. A., and Willett, W. C. Intake of carotenoids and retinol in relation to risk of prostate cancer. J. Natl. Cancer Inst. (Bethesda), 87: 1767-1776, 1995.
4. Mills, P. K., Beeson, W. L., Phillips, R. L., and Fraser, G. E. Cohort study of diet, lifestyle, and prostate cancer in Adventist men. Cancer (Phila.), 64: 598-604, 1989.
5. Hsing, A. W., Comstock, G. W., Abbey, H., and Polk, B. F. Serologic precursors of cancer: retinol, carotenoids, and tocopherol and risk of prostate cancer. J. Natl. Cancer Inst. (Bethesda), 82: 941-946, 1990.
6. Gerster, H. The potential role of lycopene for human health. J. Am. Coll. Nutr., 16: 109-126, 1997.
7. Stahl, W., and Sies, H. Lycopene: a biologically important carotenoid for humans? Arch. Biochem. Biophys., 336: 1-9, 1996.
8. Hennekens, C. H., Buring, J. E., Manson, J. E., Stampfer, M., Rosner, B., Cook, N. R., Belanger, C., LaMotte, F., Gaziano, J. M., Ridker, P. M., Willett, W., and Peto, R. Lack of effect of long-term supplementation with β carotene on the incidence of malignant neoplasms and cardiovascular disease. N. Engl. J. Med., 334: 1145-1149, 1996.
9. Comstock, G. W., Norkus, E. P., Hoffman, S. C., Xu, M. W., and Helzlsouer, K. J. Stability of ascorbic acid, carotenoids, retinol, and tocopherols in plasma stored at -70 degrees C for 4 years. Cancer Epidemiol. Biomark. Prev., 4: 505-507, 1995.
10. Catalona, W. J., and Avioli, L. V. Diagnosis, staging, and surgical management of prostatic carcinoma. Arch. Intern. Med., 147: 361-363, 1987.
11. Rothman, K. J. Modern Epidemiology, pp. 285-310. Boston: Little, Brown, 1986.
12. Clark, L. C. Dalkin, B., Krongrad, A., Combs, G. F., Jr., Turnbull, B. W., Slate, E. H., Witherington, R., Herlong, J. H., Janosko, E., Carpenter, D., Borosso, C., Folk, S., and Rounder, J. Decreased incidence of prostate cancer with selenium supplementation: results of a double-blind cancer prevention trial. Br J. Urol., 81: 730-734, 1998.
13. Yoshizawa, K., Willett, W. C., Morris, S. J., Stampfer, M. J., Spiegelman, D., Rimm, E. B., and Giovannucci, E. Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer. J. Natl. Cancer Inst., 90: 1219-1224, 1998.
14. Heinonen, O. P., Albanes, D., Virtamo, J., Taylor, P. R., Huttunen, J. K., Hartman, A. M., Haapakoski, J., Malila, N., Rautalahti, M., Ripatti, S., Maenpaa, H., Teerenhori, L., Kos, L., Virolainen, M., and Edwards, B. K. Prostate cancer and supplementation with α-tocopherol and β-carotene: incidence and mortality in a controlled trial. J. Natl. Cancer Inst. (Bethesda), 90: 440-446, 1998.
15. Stahl, W., and Sies, H. Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans. J. Nutr., 122: 2161-2166, 1992.
16. Di Mascio, P., Kaiser, S., and Sies, H. Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch. Biochem. Biophys., 274: 532-538, 1989.
17. Miller, N. J., Sampson, J., Candeias, L. P., Bramley, P. M., and Rice-Evans, C. A. Antioxidant activities of carotenes and xanthophylls. FEBS Lett., 384: 240-242, 1996.
18. Trinkler, J. H., Bohm, F., Schalen, W., and Truscott, T. G. Dietary carotenoids protect human cells from damage. J. Photochem. Photobiol., 26: 283-285, 1994.
19. Ripple, M. O., Henry, W. F., Rago, R. P., and Wilding, G. Pro-oxidant-antioxidant shift induced by androgen treatment of human prostate carcinoma cells. J. Natl. Cancer Inst. (Bethesda), 89: 40-48, 1997.
20. Malins, D. C., Polissar, N. L., and Gunselman, S. J. Models of DNA structure achieve almost perfect discrimination between normal prostate, benign prostatic hyperplasia (BPH), and adenocarcinoma and have a high potential for predicting BPH and prostate cancer. Proc. Natl. Acad. Sci. USA, 94: 259-264, 1997.
21. Zhang, L. X., Cooney, R. V., and Bertram, J. S. Carotenoids up-regulate connexin43 gene expression independent of their provitamin A or antioxidant properties. Cancer Res., 52: 5707-5712, 1992.
22. Bankson, D D., Countryman, C. J., and Collins, S. J. Potentiation of the retinoic acid-induced differentiation of HL-60 cells by lycopene. Am. J. Clin. Nutr., 53 (Suppl.): P-13, 1991.
23. Matsushima-Nishiwaki, R., Shidoji, Y., Nishiwaki, S., Yamada, T., Moriwaki, H., and Muto, Y. Suppression by carotenoids of microcystin-induced morphological changes in mouse hepatocytes. Lipids, 30: 1029-1034, 1995.
24. Levy, J., Bosin, E., Feldman, B., Giat, Y., Miinster, A., Danilenko, M., and Sharoni, Y. Lycopene is a more potent inhibitor of human cancer cell proliferation than either α-carotene or β-carotene. Nutr. Cancer, 24: 257-266, 1995.
25. Nagasawa, H., Mitamura, T., Sakamoto, S., and Yamamoto, K. Effects of lycopene on spontaneous mammary tumour development in SHN virgin mice. Anticancer Res., 15: 1173-1178, 1995.
26. Sharoni, Y., Giron, E., Rise, M., and Levy, J. Effects of lycopene-enriched oleoresin on 7,12-dimethyl-benz[a]anthracene-induced rat mammary tumors. Cancer Detect. Prev., 21: 118-123, 1997.
27. Stahl, W., Schwarz, W., Sundquist, A. R., and Sies H. cis-trans isomers of lycopene and β-carotene in human serum and tissues. Arch. Biochem. Biophys., 294: 173-177, 1992.
28. Clinton, S. K., Emenhiser, C., Schwartz, S. J., Bostwick, D. G., Williams, A. W., Moore, B. J., and Erdman, J. W. cis-trans lycopene isomers, carotenoids, and retinol in the human prostate. Cancer Epidemiol. Biomark. Prev., 5: 823-833, 1996.
29. Buiatti, E., Palli, D., Decarli, A., Amadori, D., Avellini, C., Bianchi, S., Biserni, R., Cipriani, F., Cocco, P., Giacosa, A., Marubini, E., Puntoni, R., Vindigni, C., Fraumeni, J., and Blot, W. A case-control study of gastric cancer and diet in Italy. Int. J. Cancer, 44: 611-616, 1989.
30. Franceschi, S., Bidoli, E., La Vecchia, C., Talamini, R., D'Avanzo, B., and Negri, E. Tomatoes and risk of digestive-tract cancers. Int. J. Cancer, 59: 181-184, 1994.
31. Bueno de Mesquita, H. B., Maisonneuve, P., Runia, S., and Moerman, C. J. Intake of foods and nutrients and cancer of the exocrine pancreas: a population-based case-control study in the Netherlands. Int. J. Cancer, 48: 540-549, 1991.
32. Colditz, G. A., Branch, L. G., and Lipnick, RJ. Increased green and yellow vegetable intake and lowered cancer deaths in an elderly population. Am. J. Clin. Nutr., 41: 32-36, 1985.
33. Schuman, L. M., Mandel, J. S., Radke, A., Seal, U., and Halberg, F. Some selected features of the epidemiology of prostatic cancer: Minneapolis-St. Paul, Minnesota, case-control study, 1976-1979. In: Magnus, K. (ed.), Trends in Cancer Incidence: Causes and Practical Implications, pp. 345-354. Washington, DC: Hemisphere, 1982.
34. Le Marchand, L., Hankin, J. H., Kolonel, L. N., and Wilkens, L. R. Vegetable and fruit consumption in relation to prostate cancer risk in Hawaii: a reevaluation of the effect of dietary β-carotene Am. J. Epidemiol., 133: 215-219, 1991.
35. Nomura, A. M. Y., Stemmermann, G. N., Lee, J., and Craft, N. E. Serum micronutrients and prostate cancer in Japanese Americans in Hawaii. Cancer Epidemiol. Biomark. Prev., 6: 487-491, 1997.
36. Graham, S., Haughey, B., Marshall, J., Priore, R., Byers, T., Rzepka, T., Mettlin, C., and Pontes, J. E. Diet in the epidemiology of carcinoma of the prostate gland. J. Natl. Cancer Inst. (Bethesda), 70: 687-692, 1983.
37. West, D. W., Slattery, M. L., Robinson, L. M., French, T. K., and Mahoney, A. W. Adult dietary intake and prostate cancer risk in Utah, a case-control study with special emphasis on aggressive tumors. Cancer Causes Control, 2: 85-94, 1991
38. Kolonel, L. N., Yoshizawa, C. N., and Hankin, J. H. Diet and prostatic cancer: a case-control study in Hawaii. Am. J. Epidemiol., 127: 999-1011, 1988.
39. Talamini, R., Franceschi, S., La Vecchia, C., Serraino, D., Barra, S., and Negri, E. Diet and prostatic cancer: a case-control study in Northern Italy. Nutr. Cancer, 18: 277-286, 1992.
40. Ross, R. K., Shimizu, H., Paganini-Hill, A., Honda, G., and Henderson B. E. Case-control studies of prostate cancer in blacks and whites in Southern California. J. Natl. Cancer Inst. (Bethesda), 78: 869-874, 1987.
41. Hsing, A. W., McLaughlin, J. K., Schuman, L. M., Bjelke, E., Gridley, G., Wacholder, S., Chien, H. T., and Blot, W. J. Diet, tobacco use, and fatal prostate cancer results from the Lutheran Brotherhood Cohort Study. Cancer Res., 50: 6838-6840, 1990.
42. Middleton, B., Byers, T., Marshall, J., and Graham, S. Dietary vitamin A and cancer: a multisite case-control study. Nutr. Cancer, 8: 101-116, 1986.
43. Ohno, Y., Yoshida, O., Oishi, K., Okada, K., Yamabe, H., and Schroeder, F. H. Dietary β-carotene and cancer of the prostate: a case-control study in Kyoto. Japan. Cancer Res., 48: 1331-1336, 1988.
44. Hayes, R. B., Bogdanovica, J. F. A. T., Schroeder, F. H., De Bruijn, A., Raatgever, J. W., Van Der Maas, P. J., Oishi, K., and Yoshida, O. Serum retinol and prostate cancer. Cancer (Phila.), 62: 2021-2026, 1988.
45. Reichman, M. E., Hayes, R. B., Ziegler, R. G., Schatzkin, A., Taylor, P. R., Kahle, L. L., and Fraumeni, J. F., Jr. Serum vitamin A and subsequent development of prostate cancer in the First National Health and Nutrition Examination Survey Epidemiologic Follow-up Study. Cancer Res., 50: 2311-2315, 1990.
46. Knekt, P., Aromaa, A., Maatela, J., Aaran, R., Nikkari, T., Hakama, M., Hakulinen, T., Peto, R., Saxen, E., and Teppo, L. Serum vitamin E and risk of cancer among Finnish men during a 10-year follow-up. Am. J. Epidemiol., 127: 28-41, 1988.
47. Bendich, A., and Shapiro, S. S. Effect of β-carolene and canthaxanthin on the immune response of rats. J. Nutr, 116: 2254-2262, 1986.
48. Xu, M. J., Plezia, P. M., Alberts, D. S., Emerson, S. S., Peng, Y. M., Sayers, S. M., Liu, Y., Ritenbaugh, C , and Gensler, H. L. Reduction in plasma or skin alpha-locopherol concentration with long-term oral administration of beta-carotene in humans and mice. J. Natl. Cancer Inst. (Bethesda), 84: 1559-1565, 1992.
49. Fotouhi, N., Meydani, M., Santos, M. S., Meydani, S. N., Hennekens, C. H., and Gaziano, J. M. Carotenoid and tocopherol concentrations in plasma, peripheral blood mononuclear cells, and red blood cells after long-term β-carotene supplementation in men. Am. J. Clin. Nutr., 63: 553-558, 1996.
50. Gärtner, C., Stahl, W., and Sies, H. Lycopene is more bioavailable from tomato paste than from fresh tomatoes. Am. J. Clin. Nutr., 66: 116-122, 1997.