메뉴 건너뛰기




Volumn 34, Issue 3, 2008, Pages 209-217

Effect of Ccapsaicin on tNOX (ENOX2) protein expression in stomach cancer cells

Author keywords

Apoptosis; Capsaicin; Downregulation; SCM cells; Tumor associated NADH oxidase (tNOX, also as ENOX2)

Indexed keywords

AGENTS ACTING ON THE PERIPHERAL NERVOUS AND NEUROMUSCULAR SYSTEMS; CAPSAICIN; OXIDOREDUCTASE; TUMOR ASSOCIATED NADH OXIDASE; TUMOR-ASSOCIATED NADH OXIDASE;

EID: 74049102383     PISSN: 09516433     EISSN: 18728081     Source Type: Journal    
DOI: 10.3233/BIO-2009-1074     Document Type: Article
Times cited : (32)

References (36)
  • 1
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • B.B. Aggarwal and S. Shishodia, Molecular targets of dietary agents for prevention and therapy of cancer, Biochem Parmacol 71 (2006), 1397-1421.
    • (2006) Biochem Parmacol , vol.71 , pp. 1397-1421
    • Aggarwal, B.B.1    Shishodia, S.2
  • 2
    • 55849096218 scopus 로고    scopus 로고
    • A comparative proteomic analysis for capsaicin-induced apoptosis between human hepatocarcinoma (HepG2) and human neuroblastoma (SK-N-SH) cells
    • Y.M. Baek, H.J. Hwang, S.W. Kim, H.S. Hwang, S.H. Lee, J.A. Kim and J.W. Yun, A comparative proteomic analysis for capsaicin-induced apoptosis between human hepatocarcinoma (HepG2) and human neuroblastoma (SK-N-SH) cells, Proteomics 8 (2008), 4748-4767.
    • (2008) Proteomics , vol.8 , pp. 4748-4767
    • Baek, Y.M.1    Hwang, H.J.2    Kim, S.W.3    Hwang, H.S.4    Lee, S.H.5    Kim, J.A.6    Yun, J.W.7
  • 3
    • 34249792353 scopus 로고    scopus 로고
    • Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation
    • M. Bhutani, A.K. Pathak, A.S. Nair, A.B. Kunnumakkara, S. Guha, G. Sethi and B.B., Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation, Clin Cancer Res 13 (2007), 3024-3032.
    • (2007) Clin Cancer Res , vol.13 , pp. 3024-3032
    • Bhutani, M.1    Pathak, A.K.2    Nair, A.S.3    Kunnumakkara, A.B.4    Guha, S.5    Sethi, G.6    B.B.7
  • 4
    • 0026772314 scopus 로고
    • Stimulation of NADH oxidase activity from rat liver plasma membranes by growth factors and hormones is decreased or absent with hepatoma plasma membranes
    • M. Bruno, A.O. Brightman, J. Lawrence, D. Werderitsh, D.M. Morré and D.J Morré, Stimulation of NADH oxidase activity from rat liver plasma membranes by growth factors and hormones is decreased or absent with hepatoma plasma membranes, Biochemistry J 284 (1992), 625-628.
    • (1992) Biochemistry J , vol.284 , pp. 625-628
    • Bruno, M.1    Brightman, A.O.2    Lawrence, J.3    Werderitsh, D.4    Morré, D.M.5    Morré, D.J.6
  • 5
    • 34249714358 scopus 로고    scopus 로고
    • Effect of polyclonal antisera to recombinant tNOX protein on the growth of transformed cells
    • C.F. Chen, S. Huang, S.C. Liu and P.J. Chueh, Effect of polyclonal antisera to recombinant tNOX protein on the growth of transformed cells, BioFactors 28 (2006), 119-133.
    • (2006) BioFactors , vol.28 , pp. 119-133
    • Chen, C.F.1    Huang, S.2    Liu, S.C.3    Chueh, P.J.4
  • 6
    • 33947304343 scopus 로고    scopus 로고
    • TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells-mechanisms behind a possible new "hot" cancer treatment
    • J. Chow, M. Norng, J. Chang and J. Chai, TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells-mechanisms behind a possible new "hot" cancer treatment, Biochim Biophys Acta 1773 (2007), 565-576.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 565-576
    • Chow, J.1    Norng, M.2    Chang, J.3    Chai, J.4
  • 7
    • 0033922168 scopus 로고    scopus 로고
    • Cell membrane redox systems and transformation
    • P.J. Chueh, Cell membrane redox systems and transformation, Antioxidants & Redox Signaling 2 (2000), 177-187.
    • (2000) Antioxidants & Redox Signaling , vol.2 , pp. 177-187
    • Chueh, P.J.1
  • 8
    • 0037133540 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a tumor-associated, growth-related, and time-keeping hydroquinone (NADH) oxidase (tNOX) of the HeLa cell surface
    • P.J. Chueh, C. Kim, N. Cho, D.M. Morré and D.J. Morré, Molecular cloning and characterization of a tumor-associated, growth-related, and time-keeping hydroquinone (NADH) oxidase (tNOX) of the HeLa cell surface, Biochemistry 41 (2002), 3732-3742.
    • (2002) Biochemistry , vol.41 , pp. 3732-3742
    • Chueh, P.J.1    Kim, C.2    Cho, N.3    Morré, D.M.4    Morré, D.J.5
  • 9
    • 0031172858 scopus 로고    scopus 로고
    • A 33.5 kD heat- and protease-resistant NADH oxidase inhibited by capsaicin from sera of cancer patients
    • P.J. Chueh, D.J. Morré, F.E.Wilkinson, J. Gibson and D.M. Morré, A 33.5 kD heat- and protease-resistant NADH oxidase inhibited by capsaicin from sera of cancer patients, Arch Biochem Biophys 342 (1997), 38-47.
    • (1997) Arch Biochem Biophys , vol.342 , pp. 38-47
    • Chueh, P.J.1    Morré, D.J.2    Wilkinson, F.E.3    Gibson, J.4    Morré, D.M.5
  • 10
    • 0037203806 scopus 로고    scopus 로고
    • A site-directed mutagenesis analysis of tNOX functional domains
    • P.J. Chueh, D.M. Morré and D.J. Morré. A site-directed mutagenesis analysis of tNOX functional domains, Biochim Biophys Acta 1594 (2002), 74-83.
    • (2002) Biochim Biophys Acta , vol.1594 , pp. 74-83
    • Chueh, P.J.1    Morré, D.M.2    Morré, D.J.3
  • 11
    • 13444304185 scopus 로고    scopus 로고
    • Tnox is both necessary and sufficient as a cellular target for the anticancer actions of capsaicin and the green tea catechin (-)-epigallocatechin-3-gallate
    • P.J. Chueh, L.-Y. Wu, D.M. Morré and D.J. Morré, tNOX is both necessary and sufficient as a cellular target for the anticancer actions of capsaicin and the green tea catechin (-)-epigallocatechin-3-gallate, BioFactors 20 (2004), 249-263.
    • (2004) BioFactors , vol.20 , pp. 249-263
    • Chueh, P.J.1    Wu, L.-Y.2    Morré, D.M.3    Morré, D.J.4
  • 12
    • 0025871477 scopus 로고
    • Capsaicin: Cellular targets, mechanisms of action, and selectivity for thin sensory neurons
    • P. Holzer, Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons, Pharmacol Rev 43 (1994), 143-201.
    • (1994) Pharmacol Rev , vol.43 , pp. 143-201
    • Holzer, P.1
  • 13
    • 12144286272 scopus 로고    scopus 로고
    • Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: Implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species
    • K. Ito, T. Nakazato, A. Murakami, K. Yamato, Y. Miyakawa, T.Yamada, N. Hozumi, H. Ohigashi, Y. Ikeda and M. Kizaki, Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species, Clin Cancer Res 10 (2004), 2120-2130.
    • (2004) Clin Cancer Res , vol.10 , pp. 2120-2130
    • Ito, K.1    Nakazato, T.2    Murakami, A.3    Yamato, K.4    Miyakawa, Y.5    Yamada, T.6    Hozumi, N.7    Ohigashi, H.8    Ikeda, Y.9    Kizaki, M.10
  • 14
    • 0842304283 scopus 로고    scopus 로고
    • Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: Implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species
    • K. Ito, T. Nakazato, K. Yamato, Y. Miyakawa, T. Yamada, N. Hozumi, K. Segawa, Y. Ikeda and M. Kizaki, Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species, Cancer Res 64 (2004), 1071-1078.
    • (2004) Cancer Res , vol.64 , pp. 1071-1078
    • Ito, K.1    Nakazato, T.2    Yamato, K.3    Miyakawa, Y.4    Yamada, T.5    Hozumi, N.6    Segawa, K.7    Ikeda, Y.8    Kizaki, M.9
  • 15
    • 33847785854 scopus 로고    scopus 로고
    • Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin
    • W. Johnson, Jr., Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin, Int J Toxicol 26 (2007) 3-106.
    • (2007) Int J Toxicol , vol.26 , pp. 3-106
    • Johnson, W.1
  • 17
    • 34247898927 scopus 로고    scopus 로고
    • Involvement of AMPK signaling cascade in capsaicininduced apoptosis of HT-29 colon cancer cells
    • Y.M. Kim, J.T. Hwang, D.W. Kwak, Y.K. Lee and O.J. Park, Involvement of AMPK signaling cascade in capsaicininduced apoptosis of HT-29 colon cancer cells, Ann N Y Acad Sci 1095 (2007), 496-503.
    • (2007) Ann N Y Acad Sci , vol.1095 , pp. 496-503
    • Kim, Y.M.1    Hwang, J.T.2    Kwak, D.W.3    Lee, Y.K.4    Park, O.J.5
  • 18
    • 0030713333 scopus 로고    scopus 로고
    • Capsaicin can alter the expression of tumor forming-related genes which might be followed by induction of apoptosis of a Korean stomach cancer cell line, SNU-1
    • J.D. Kim, J.M. Kim and J.O. Pyo, Capsaicin can alter the expression of tumor forming-related genes which might be followed by induction of apoptosis of a Korean stomach cancer cell line, SNU-1, Cancer Lett 120 (1997), 235-241.
    • (1997) Cancer Lett , vol.120 , pp. 235-241
    • Kim, J.D.1    Kim, J.M.2    Pyo, J.O.3
  • 19
    • 4644295000 scopus 로고    scopus 로고
    • Capsaicin, a spicy component of hot pepper, induces apoptosis by activation of the peroxisome proliferators-activated receptor gamma in HT-29 human colon cancer cells
    • C.S. Kim, W.H. Park, J.Y. Park, J.H. Kang, M.O. Kim, T. Kawada, H. Yoo, I.S. Han and R. Yu, Capsaicin, a spicy component of hot pepper, induces apoptosis by activation of the peroxisome proliferators-activated receptor gamma in HT-29 human colon cancer cells, J Med Food 7 (2004), 267-273.
    • (2004) J Med Food , vol.7 , pp. 267-273
    • Kim, C.S.1    Park, W.H.2    Park, J.Y.3    Kang, J.H.4    Kim, M.O.5    Kawada, T.6    Yoo, H.7    Han, I.S.8    Yu, R.9
  • 20
    • 1842431016 scopus 로고    scopus 로고
    • Involvement of NADPH oxidase-mediated generation of reactive oxygen species in the apototic cell death by capsaicin in HepG2 human hepatoma cells
    • Y.S. Lee, Y.S. Kang, J.S. Lee, S. Nicolova and J.A. Kim, Involvement of NADPH oxidase-mediated generation of reactive oxygen species in the apototic cell death by capsaicin in HepG2 human hepatoma cells, Free Radic Res 38 (2004), 405-412.
    • (2004) Free Radic Res , vol.38 , pp. 405-412
    • Lee, Y.S.1    Kang, Y.S.2    Lee, J.S.3    Nicolova, S.4    Kim, J.A.5
  • 21
    • 36849021716 scopus 로고    scopus 로고
    • RNAinterference targeting tNOXattenuates cell migration via a mechanism that involved membrane association of Rac
    • S.C. Liu, J.J.Yang, K.N. Shao and P.J. Chueh, RNAinterference targeting tNOXattenuates cell migration via a mechanism that involved membrane association of Rac, Biochem Biophys Res Commun 365 (2008), 672-677.
    • (2008) Biochem Biophys Res Commun , vol.365 , pp. 672-677
    • Liu, S.C.1    Yang, J.J.2    Shao, K.N.3    Chueh, P.J.4
  • 23
    • 53049104152 scopus 로고    scopus 로고
    • Stress-induced downregulation of tumorassociated NADH oxidase during apoptosis in transformed cell
    • L.C. Mao, H.M. Wang, Y.Y. Lin, T.K. Chang, Y.H. Hsin and P.J. Chueh, Stress-induced downregulation of tumorassociated NADH oxidase during apoptosis in transformed cell, FEBS Lett 582 (2008), 3445-3450.
    • (2008) FEBS Lett , vol.582 , pp. 3445-3450
    • Mao, L.C.1    Wang, H.M.2    Lin, Y.Y.3    Chang, T.K.4    Hsin, Y.H.5    Chueh, P.J.6
  • 25
    • 0029608917 scopus 로고
    • NADH oxidase activity of HeLa plasma membranes inhibited by the antitumor sulfonylurea N-(4- methylphenylsulfonyl)-N’-(4-chlorophenyl) urea (LY181984) at an external site
    • D.J. Morré, NADH oxidase activity of HeLa plasma membranes inhibited by the antitumor sulfonylurea N-(4- methylphenylsulfonyl)-N’-(4-chlorophenyl) urea (LY181984) at an external site, Biochim Biophys Acta 1240 (1995), 201-208.
    • (1995) Biochim Biophys Acta , vol.1240 , pp. 201-208
    • Morré, D.J.1
  • 26
    • 0034308086 scopus 로고    scopus 로고
    • Preferential inhibition by (-)-epigallocatechin-3-gallate of the cell surface NADH oxidase and growth of transformed cells in culture
    • Morré, D.J., A. Bridge, L.-Y. Wu and D.M. Morré, Preferential inhibition by (-)-epigallocatechin-3-gallate of the cell surface NADH oxidase and growth of transformed cells in culture, Biochem Pharmacol 60 (2000), 937-946.
    • (2000) Biochem Pharmacol , vol.60 , pp. 937-946
    • Morré, D.J.1    Bridge, A.2    Wu, L.-Y.3    Morré, D.M.4
  • 27
    • 0028925916 scopus 로고
    • Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture
    • D.J. Morré, P.J. Chueh and D.M. Morré, Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture, Proc Natl Acad Sci USA 92 (1995), 1831-1835.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1831-1835
    • Morré, D.J.1    Chueh, P.J.2    Morré, D.M.3
  • 29
    • 0036378890 scopus 로고    scopus 로고
    • Capsaicin regulates vascular endothelial cell growth factor expression by modulation of hypoxia inducing factor-1alpha in human malignant melanoma cells
    • P.S. Patel, S. Yang, A. Li, M.L. Varnev and R.K. Singh, Capsaicin regulates vascular endothelial cell growth factor expression by modulation of hypoxia inducing factor-1alpha in human malignant melanoma cells, J Cancer Res Clin Oncol 128 (2002), 461-468.
    • (2002) J Cancer Res Clin Oncol , vol.128 , pp. 461-468
    • Patel, P.S.1    Yang, S.2    Li, A.3    Varnev, M.L.4    Singh, R.K.5
  • 31
    • 34848895758 scopus 로고    scopus 로고
    • Apoptosis induced by capsaicin in prostate PC-3 cells invovles ceramide accumulation, neutral sphingomyelinase, and JNK activation
    • A.M. Sánchez, S. Malagarie-Cazenave, N. Olea, D. Vara, A. Chiloeches and I. Díaz-Laviada, Apoptosis induced by capsaicin in prostate PC-3 cells invovles ceramide accumulation, neutral sphingomyelinase, and JNK activation, Apoptosis 12 (2007), 2013-2024.
    • (2007) Apoptosis , vol.12 , pp. 2013-2024
    • Sánchez, A.M.1    Malagarie-Cazenave, S.2    Olea, N.3    Vara, D.4    Chiloeches, A.5    Díaz-Laviada, I.6
  • 32
    • 31444437266 scopus 로고    scopus 로고
    • Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin
    • A.M. Sánchez, M.G. Sánchez, S. Malagarie-Cazenave, N. Olea and I. Díaz-Laviada, Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin, Apoptosis 11 (2006), 89-99.
    • (2006) Apoptosis , vol.11 , pp. 89-99
    • Sánchez, A.M.1    Sánchez, M.G.2    Malagarie-Cazenave, S.3    Olea, N.4    Díaz-Laviada, I.5
  • 33
    • 0037019748 scopus 로고    scopus 로고
    • More than spice: Capsaicin in hot chili peppers makes tumor cells commit suicide
    • Y.J. Surh, More than spice: capsaicin in hot chili peppers makes tumor cells commit suicide, J Natl Cancer Inst 94 (2002), 1263-1265.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1263-1265
    • Surh, Y.J.1
  • 34
    • 32544439717 scopus 로고    scopus 로고
    • Apoptosis induction by dohevanil, a DHA substitutive analog of capsaicin, in MCF-7 cells
    • Tuoya, N. Baba, Y. Shimoishi, Y. Murata, M. Tada, M. Koseki and K. Takahata, Apoptosis induction by dohevanil, a DHA substitutive analog of capsaicin, in MCF-7 cells, Life Sci 78 (2006), 1515-1519.
    • (2006) Life Sci , vol.78 , pp. 1515-1519
    • Baba, T.N.1    Shimoishi, Y.2    Murata, Y.3    Tada, M.4    Koseki, M.5    Takahata, K.6
  • 35
    • 34247859081 scopus 로고    scopus 로고
    • Mouse embryonic fibroblast cells from transgenic mice overexpressing tNOX exhibit an altered growth and drug response phenotype
    • K. Yagiz, L.-Y. Wu, C.P. Kuntz, D.J. Morré and D.M. Morré, Mouse embryonic fibroblast cells from transgenic mice overexpressing tNOX exhibit an altered growth and drug response phenotype, J Cell Biochem 101 (2007), 295-306.
    • (2007) J Cell Biochem , vol.101 , pp. 295-306
    • Yagiz, K.1    Wu, L.-Y.2    Kuntz, C.P.3    Morré, D.J.4    Morré, D.M.5
  • 36
    • 56349151331 scopus 로고    scopus 로고
    • In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway
    • R. Zhang, I. Humphreys, R.P., Sahu, Y. Shi and S.K. Srivastava, In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway, Apoptosis 13 (2008), 1465-1478.
    • (2008) Apoptosis , vol.13 , pp. 1465-1478
    • Zhang, R.1    Humphreys, I.2    Sahu, R.P.3    Shi, Y.4    Srivastava, S.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.