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Volumn 26, Issue 11-12, 2010, Pages 1181-1187

The carotenoid lycopene differentially regulates phase I and II enzymes in dimethylbenz[a]anthracene-induced MCF-7 cells

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DIMETHYLBENZ[A]ANTHRACENE; ETHOXYRESORUFIN DEETHYLASE; LYCOPENE;

EID: 77957763728     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nut.2009.11.013     Document Type: Article
Times cited : (41)

References (46)
  • 1
    • 0026539631 scopus 로고
    • Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans
    • Stahl W., Sies H. Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans. J Nutr 1992, 122:2161-2166.
    • (1992) J Nutr , vol.122 , pp. 2161-2166
    • Stahl, W.1    Sies, H.2
  • 2
    • 0030838318 scopus 로고    scopus 로고
    • Relative stability of carotenoid radical cations and homologue tocopheroxyl radicals. A real time kinetic study of antioxidant hierarchy
    • Mortensen A., Skibsted L.H. Relative stability of carotenoid radical cations and homologue tocopheroxyl radicals. A real time kinetic study of antioxidant hierarchy. FEBS Lett 1997, 417:261-266.
    • (1997) FEBS Lett , vol.417 , pp. 261-266
    • Mortensen, A.1    Skibsted, L.H.2
  • 3
    • 0024464691 scopus 로고
    • Lycopene as the most efficient biological carotenoid singlet oxygen quencher
    • Di Mascio P., Kaiser S., Sies H. Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch Biochem Biophys 1989, 274:532-538.
    • (1989) Arch Biochem Biophys , vol.274 , pp. 532-538
    • Di Mascio, P.1    Kaiser, S.2    Sies, H.3
  • 4
    • 0033819464 scopus 로고    scopus 로고
    • Role of antioxidant lycopene in cancer and heart disease
    • Rao A.V., Agarwal S. Role of antioxidant lycopene in cancer and heart disease. J Am Coll Nutr 2000, 19:563-569.
    • (2000) J Am Coll Nutr , vol.19 , pp. 563-569
    • Rao, A.V.1    Agarwal, S.2
  • 5
    • 34047160095 scopus 로고    scopus 로고
    • Carotenoids and human health
    • Rao A.V., Rao L.G. Carotenoids and human health. Pharmacol Res 2007, 55:207-216.
    • (2007) Pharmacol Res , vol.55 , pp. 207-216
    • Rao, A.V.1    Rao, L.G.2
  • 7
    • 18744394900 scopus 로고    scopus 로고
    • Lycopene inhibits proliferation and enhances gap-junction communication of KB-1 human oral tumor cells
    • Livny O., Kaplan I., Reifen R., Polak-Charcon S., Madar Z., Schwartz B. Lycopene inhibits proliferation and enhances gap-junction communication of KB-1 human oral tumor cells. J Nutr 2002, 132:3754-3759.
    • (2002) J Nutr , vol.132 , pp. 3754-3759
    • Livny, O.1    Kaplan, I.2    Reifen, R.3    Polak-Charcon, S.4    Madar, Z.5    Schwartz, B.6
  • 8
    • 36248985688 scopus 로고    scopus 로고
    • Air pollution combustion emissions: characterization of causative agents and mechanisms associated with cancer, reproductive, and cardiovascular effects
    • Lewtas J. Air pollution combustion emissions: characterization of causative agents and mechanisms associated with cancer, reproductive, and cardiovascular effects. Mutat Res 2007, 636:95-133.
    • (2007) Mutat Res , vol.636 , pp. 95-133
    • Lewtas, J.1
  • 9
    • 0030024024 scopus 로고    scopus 로고
    • Aromatic DNA adducts in adjacent tissues of breast cancer patients: clues to breast cancer etiology
    • Li D., Wang M., Dhingra K., Hittelman W.N. Aromatic DNA adducts in adjacent tissues of breast cancer patients: clues to breast cancer etiology. Cancer Res 1996, 56:287-293.
    • (1996) Cancer Res , vol.56 , pp. 287-293
    • Li, D.1    Wang, M.2    Dhingra, K.3    Hittelman, W.N.4
  • 10
    • 0034660372 scopus 로고    scopus 로고
    • An aryl hydrocarbon receptor conformation acts as the functional core of nuclear dioxin signaling
    • Kronenberg S., Esser C., Carlberg C. An aryl hydrocarbon receptor conformation acts as the functional core of nuclear dioxin signaling. Nucleic Acids Res 2000, 28:2286-2291.
    • (2000) Nucleic Acids Res , vol.28 , pp. 2286-2291
    • Kronenberg, S.1    Esser, C.2    Carlberg, C.3
  • 11
    • 0035977882 scopus 로고    scopus 로고
    • Molecular biology of the Ah receptor and its role in carcinogenesis
    • Safe S. Molecular biology of the Ah receptor and its role in carcinogenesis. Toxicol Lett 2001, 120:1-7.
    • (2001) Toxicol Lett , vol.120 , pp. 1-7
    • Safe, S.1
  • 12
    • 0034662379 scopus 로고    scopus 로고
    • Effect of 3'-methoxy-4'-nitroflavone on benzo[a]pyrene toxicity. Aryl hydrocarbon receptor-dependent and -independent mechanisms
    • Dertinger S.D., Lantum H.B., Silverstone A.E., Gasiewicz T.A. Effect of 3'-methoxy-4'-nitroflavone on benzo[a]pyrene toxicity. Aryl hydrocarbon receptor-dependent and -independent mechanisms. Biochem Pharmacol 2000, 60:189-196.
    • (2000) Biochem Pharmacol , vol.60 , pp. 189-196
    • Dertinger, S.D.1    Lantum, H.B.2    Silverstone, A.E.3    Gasiewicz, T.A.4
  • 14
    • 0033514998 scopus 로고    scopus 로고
    • Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas
    • Buters J.T., Sakai S., Richter T., Pineau T., Alexander D.L., Savas U., et al. Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas. Proc Natl Acad Sci USA 1999, 96:1977-1982.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1977-1982
    • Buters, J.T.1    Sakai, S.2    Richter, T.3    Pineau, T.4    Alexander, D.L.5    Savas, U.6
  • 15
    • 0036168607 scopus 로고    scopus 로고
    • Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation
    • Kleiner H.E., Vulimiri S.V., Reed M.J., Uberecken A., DiGiovanni J. Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation. Chem Res Toxicol 2002, 15:226-235.
    • (2002) Chem Res Toxicol , vol.15 , pp. 226-235
    • Kleiner, H.E.1    Vulimiri, S.V.2    Reed, M.J.3    Uberecken, A.4    DiGiovanni, J.5
  • 16
    • 0035872470 scopus 로고    scopus 로고
    • Dibenzoylmethane modulates aryl hydrocarbon receptor function and expression of cytochromes P50 1A1, 1A2, and 1B1
    • MacDonald C.J., Ciolino H.P., Yeh G.C. Dibenzoylmethane modulates aryl hydrocarbon receptor function and expression of cytochromes P50 1A1, 1A2, and 1B1. Cancer Res 2001, 61:3919-3924.
    • (2001) Cancer Res , vol.61 , pp. 3919-3924
    • MacDonald, C.J.1    Ciolino, H.P.2    Yeh, G.C.3
  • 17
    • 0033661491 scopus 로고    scopus 로고
    • Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank
    • Fisher M.B., Vandenbranden M., Findlay K., Burchell B., Thummel K.E., Hall S.D., et al. Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank. Pharmacogenetics 2000, 10:727-739.
    • (2000) Pharmacogenetics , vol.10 , pp. 727-739
    • Fisher, M.B.1    Vandenbranden, M.2    Findlay, K.3    Burchell, B.4    Thummel, K.E.5    Hall, S.D.6
  • 18
    • 0034992376 scopus 로고    scopus 로고
    • The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines
    • Yueh M.F., Nguyen N., Famourzadeh M., Strassburg C.P., Oda Y., Guengerich F.P., et al. The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines. Carcinogenesis 2001, 22:943-950.
    • (2001) Carcinogenesis , vol.22 , pp. 943-950
    • Yueh, M.F.1    Nguyen, N.2    Famourzadeh, M.3    Strassburg, C.P.4    Oda, Y.5    Guengerich, F.P.6
  • 19
    • 0030044294 scopus 로고    scopus 로고
    • Xenobiotic responsive element-mediated transcriptional activation in the UDP-glucuronosyltransferase family 1 gene complex
    • Emi Y., Ikushiro S., Iyanagi T. Xenobiotic responsive element-mediated transcriptional activation in the UDP-glucuronosyltransferase family 1 gene complex. J Biol Chem 1996, 271:3952-3958.
    • (1996) J Biol Chem , vol.271 , pp. 3952-3958
    • Emi, Y.1    Ikushiro, S.2    Iyanagi, T.3
  • 20
    • 0034652640 scopus 로고    scopus 로고
    • Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans
    • Guillemette C., Millikan R.C., Newman B., Housman D.E. Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans. Cancer Res 2000, 60:950-956.
    • (2000) Cancer Res , vol.60 , pp. 950-956
    • Guillemette, C.1    Millikan, R.C.2    Newman, B.3    Housman, D.E.4
  • 21
    • 0029097694 scopus 로고
    • A CYP1A1 restriction fragment length polymorphism is associated with breast cancer in African-American women
    • Taioli E., Trachman J., Chen X., Toniolo P., Garte S.J. A CYP1A1 restriction fragment length polymorphism is associated with breast cancer in African-American women. Cancer Res 1995, 55:3757-3758.
    • (1995) Cancer Res , vol.55 , pp. 3757-3758
    • Taioli, E.1    Trachman, J.2    Chen, X.3    Toniolo, P.4    Garte, S.J.5
  • 24
    • 0036192664 scopus 로고    scopus 로고
    • A food-based formulation provides lycopene with the same bioavailability to humans as that from tomato paste
    • Richelle M., Bortlik K., Liardet S., Hager C., Lambelet P., Baur M., et al. A food-based formulation provides lycopene with the same bioavailability to humans as that from tomato paste. J Nutr 2002, 132:404-408.
    • (2002) J Nutr , vol.132 , pp. 404-408
    • Richelle, M.1    Bortlik, K.2    Liardet, S.3    Hager, C.4    Lambelet, P.5    Baur, M.6
  • 25
    • 0041561001 scopus 로고    scopus 로고
    • A potential protective mechanism of soya isoflavones against 7,12-dimethylbenz[a]anthracene tumour initiation
    • Chan H.Y., Leung L.K. A potential protective mechanism of soya isoflavones against 7,12-dimethylbenz[a]anthracene tumour initiation. Br J Nutr 2003, 90:457-465.
    • (2003) Br J Nutr , vol.90 , pp. 457-465
    • Chan, H.Y.1    Leung, L.K.2
  • 26
    • 10444286767 scopus 로고    scopus 로고
    • Hydroxychalcones exhibit differential effects on XRE transactivation
    • Wang H., Wang Y., Chen Z.Y., Chan F.L., Leung L.K. Hydroxychalcones exhibit differential effects on XRE transactivation. Toxicology 2005, 207:303-313.
    • (2005) Toxicology , vol.207 , pp. 303-313
    • Wang, H.1    Wang, Y.2    Chen, Z.Y.3    Chan, F.L.4    Leung, L.K.5
  • 27
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983, 65:55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 28
    • 0031438078 scopus 로고    scopus 로고
    • Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells
    • Backlund M., Johansson I., Mkrtchian S., Ingelman-Sundberg M. Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells. J Biol Chem 1997, 272:31755-31763.
    • (1997) J Biol Chem , vol.272 , pp. 31755-31763
    • Backlund, M.1    Johansson, I.2    Mkrtchian, S.3    Ingelman-Sundberg, M.4
  • 29
    • 0037203464 scopus 로고    scopus 로고
    • Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer
    • Kris-Etherton P.M., Hecker K.D., Bonanome A., Coval S.M., Binkoski A.E., Hilpert K.F., et al. Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am J Med 2002, 113(suppl 9B):71S-88S.
    • (2002) Am J Med , vol.113 , Issue.SUPPL. 9B
    • Kris-Etherton, P.M.1    Hecker, K.D.2    Bonanome, A.3    Coval, S.M.4    Binkoski, A.E.5    Hilpert, K.F.6
  • 30
    • 0030775363 scopus 로고    scopus 로고
    • Chemoprevention by lycopene of mouse lung neoplasia after combined initiation treatment with DEN, MNU and DMH
    • Kim D.J., Takasuka N., Kim J.M., Sekine K., Ota T., Asamoto M., et al. Chemoprevention by lycopene of mouse lung neoplasia after combined initiation treatment with DEN, MNU and DMH. Cancer Lett 1997, 120:15-22.
    • (1997) Cancer Lett , vol.120 , pp. 15-22
    • Kim, D.J.1    Takasuka, N.2    Kim, J.M.3    Sekine, K.4    Ota, T.5    Asamoto, M.6
  • 31
    • 0030977892 scopus 로고    scopus 로고
    • Effects of lycopene-enriched tomato oleoresin on 7,12-dimethyl-benz[a]anthracene-induced rat mammary tumors
    • Sharoni Y., Giron E., Rise M., Levy J. Effects of lycopene-enriched tomato oleoresin on 7,12-dimethyl-benz[a]anthracene-induced rat mammary tumors. Cancer Detect Prev 1997, 21:118-123.
    • (1997) Cancer Detect Prev , vol.21 , pp. 118-123
    • Sharoni, Y.1    Giron, E.2    Rise, M.3    Levy, J.4
  • 32
    • 0028272001 scopus 로고
    • Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins
    • Gonzalez F.J., Gelboin H.V. Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins. Drug Metab Rev 1994, 26:165-183.
    • (1994) Drug Metab Rev , vol.26 , pp. 165-183
    • Gonzalez, F.J.1    Gelboin, H.V.2
  • 33
    • 0041368576 scopus 로고    scopus 로고
    • The red clover (Trifolium pratense) isoflavone biochanin A modulates the biotransformation pathways of 7,12-dimethylbenz[a]anthracene
    • Chan H.Y., Wang H., Leung L.K. The red clover (Trifolium pratense) isoflavone biochanin A modulates the biotransformation pathways of 7,12-dimethylbenz[a]anthracene. Br J Nutr 2003, 90:87-92.
    • (2003) Br J Nutr , vol.90 , pp. 87-92
    • Chan, H.Y.1    Wang, H.2    Leung, L.K.3
  • 34
    • 33646740154 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbon-induced CYP1B1 activity is suppressed by perillyl alcohol in MCF-7 cells
    • Chan N.L., Wang H., Wang Y., Leung H.Y., Leung L.K. Polycyclic aromatic hydrocarbon-induced CYP1B1 activity is suppressed by perillyl alcohol in MCF-7 cells. Toxicol Appl Pharmacol 2006, 213:98-104.
    • (2006) Toxicol Appl Pharmacol , vol.213 , pp. 98-104
    • Chan, N.L.1    Wang, H.2    Wang, Y.3    Leung, H.Y.4    Leung, L.K.5
  • 35
    • 0032862195 scopus 로고    scopus 로고
    • Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol
    • Ciolino H.P., Yeh G.C. Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol. Mol Pharmacol 1999, 56:760-767.
    • (1999) Mol Pharmacol , vol.56 , pp. 760-767
    • Ciolino, H.P.1    Yeh, G.C.2
  • 36
    • 0033564553 scopus 로고    scopus 로고
    • Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially
    • Ciolino H.P., Daschner P.J., Yeh G.C. Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially. Biochem J 1999, 340(Pt 3):715-722.
    • (1999) Biochem J , vol.340 , Issue.PART 3 , pp. 715-722
    • Ciolino, H.P.1    Daschner, P.J.2    Yeh, G.C.3
  • 37
    • 0028313983 scopus 로고
    • The structure-activity relationships of flavonoids as inhibitors of cytochrome P-450 enzymes in rat liver microsomes and the mutagenicity of 2-amino-3-methyl-imidazo[4,5-f]quinoline
    • Lee H., Wang H.W., Su H.Y., Hao N.J. The structure-activity relationships of flavonoids as inhibitors of cytochrome P-450 enzymes in rat liver microsomes and the mutagenicity of 2-amino-3-methyl-imidazo[4,5-f]quinoline. Mutagenesis 1994, 9:101-106.
    • (1994) Mutagenesis , vol.9 , pp. 101-106
    • Lee, H.1    Wang, H.W.2    Su, H.Y.3    Hao, N.J.4
  • 38
    • 48249134395 scopus 로고    scopus 로고
    • Induction of human UGT1A1 by a complex of dexamethasone-GR dependent on proximal site and independent of PBREM
    • Kuno T., Togawa H., Mizutani T. Induction of human UGT1A1 by a complex of dexamethasone-GR dependent on proximal site and independent of PBREM. Mol Biol Rep 2008, 35:361-367.
    • (2008) Mol Biol Rep , vol.35 , pp. 361-367
    • Kuno, T.1    Togawa, H.2    Mizutani, T.3
  • 39
    • 0029127636 scopus 로고
    • Effects of lycopene on spontaneous mammary tumour development in SHN virgin mice
    • Nagasawa H., Mitamura T., Sakamoto S., Yamamoto K. Effects of lycopene on spontaneous mammary tumour development in SHN virgin mice. Anticancer Res 1995, 15:1173-1178.
    • (1995) Anticancer Res , vol.15 , pp. 1173-1178
    • Nagasawa, H.1    Mitamura, T.2    Sakamoto, S.3    Yamamoto, K.4
  • 40
    • 0035821778 scopus 로고    scopus 로고
    • Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2 complexes
    • Nahum A., Hirsch K., Danilenko M., Watts C.K., Prall O.W., Levy J., et al. Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2 complexes. Oncogene 2001, 20:3428-3436.
    • (2001) Oncogene , vol.20 , pp. 3428-3436
    • Nahum, A.1    Hirsch, K.2    Danilenko, M.3    Watts, C.K.4    Prall, O.W.5    Levy, J.6
  • 41
    • 17144452288 scopus 로고    scopus 로고
    • Lycopene interferes with cell cycle progression and insulin-like growth factor I signaling in mammary cancer cells
    • Karas M., Amir H., Fishman D., Danilenko M., Segal S., Nahum A., et al. Lycopene interferes with cell cycle progression and insulin-like growth factor I signaling in mammary cancer cells. Nutr Cancer 2000, 36:101-111.
    • (2000) Nutr Cancer , vol.36 , pp. 101-111
    • Karas, M.1    Amir, H.2    Fishman, D.3    Danilenko, M.4    Segal, S.5    Nahum, A.6
  • 42
    • 0033008852 scopus 로고    scopus 로고
    • Lycopene and 1,25-dihydroxyvitamin D3 cooperate in the inhibition of cell cycle progression and induction of differentiation in HL-60 leukemic cells
    • Amir H., Karas M., Giat J., Danilenko M., Levy R., Yermiahu T., et al. Lycopene and 1,25-dihydroxyvitamin D3 cooperate in the inhibition of cell cycle progression and induction of differentiation in HL-60 leukemic cells. Nutr Cancer 1999, 33:105-112.
    • (1999) Nutr Cancer , vol.33 , pp. 105-112
    • Amir, H.1    Karas, M.2    Giat, J.3    Danilenko, M.4    Levy, R.5    Yermiahu, T.6
  • 43
    • 0031964487 scopus 로고    scopus 로고
    • Relationships of serum carotenoids, retinol, alpha-tocopherol, and selenium with breast cancer risk: results from a prospective study in Columbia, Missouri (United States)
    • Dorgan J.F., Sowell A., Swanson C.A., Potischman N., Miller R., Schussler N., et al. Relationships of serum carotenoids, retinol, alpha-tocopherol, and selenium with breast cancer risk: results from a prospective study in Columbia, Missouri (United States). Cancer Causes Control 1998, 9:89-97.
    • (1998) Cancer Causes Control , vol.9 , pp. 89-97
    • Dorgan, J.F.1    Sowell, A.2    Swanson, C.A.3    Potischman, N.4    Miller, R.5    Schussler, N.6
  • 44
    • 0033559952 scopus 로고    scopus 로고
    • Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis
    • Gann P.H., Ma J., Giovannucci E., Willett W., Sacks F.M., Hennekens C.H., et al. Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. Cancer Res 1999, 59:1225-1230.
    • (1999) Cancer Res , vol.59 , pp. 1225-1230
    • Gann, P.H.1    Ma, J.2    Giovannucci, E.3    Willett, W.4    Sacks, F.M.5    Hennekens, C.H.6
  • 45
    • 0033577044 scopus 로고    scopus 로고
    • Tomatoes, tomato-based products, lycopene, and prostate cancer: review of the epidemiologic literature
    • Giovannucci E. Tomatoes, tomato-based products, lycopene, and prostate cancer: review of the epidemiologic literature. J Natl Cancer Inst 1999, 91:317-331.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 317-331
    • Giovannucci, E.1
  • 46
    • 0037106274 scopus 로고    scopus 로고
    • Cancer prevention clinical trials
    • Greenwald P. Cancer prevention clinical trials. J Clin Oncol 2002, 20(suppl 18):14S-22S.
    • (2002) J Clin Oncol , vol.20 , Issue.SUPPL. 18
    • Greenwald, P.1


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