The potential for strategies using micronutrients and heterocyclic drugs to treat invasive gliomas

Acta Neurochirurgica

Volumn 145, Issue 8, 2003, Pages 683-690

  Rooprai, H K ^a,b   Christidou, M ^a   Pilkington, G J ^a  

^a UNIVERSITY OF PORTSMOUTH   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Clomipramine; Gliomas; Micronutrients; Therapy

Indexed keywords

ANTHOCYANIN; ANTIDEPRESSANT AGENT; BIOFLAVONOID; CAROTENOID; CATECHIN; CHOKEBERRY EXTRACT; CLOMIPRAMINE; CYANIDIN 3 ARABINOSIDE; CYANIDIN 3 GALACTOSIDE; CYANIDIN 3 XYLOSIDE; DAIDZEIN; FLAVONOID; FLUOXETINE; GENISTEIN; GRAPE SEED EXTRACT; HETEROCYCLIC COMPOUND; ISOFLAVONE; LYCOPENE; NOBILETIN; NUTRACEUTICAL AGENT; PLANT EXTRACT; PROANTHOCYANIDIN; RED CLOVER EXTRACT; RUTOSIDE; SELENIUM; SEROTONIN UPTAKE INHIBITOR; TANGERETIN; TRACE ELEMENT; UNCLASSIFIED DRUG;

ANGIOGENESIS; APOPTOSIS; CANCER INVASION; CLINICAL TRIAL; GLIOMA; HUMAN; NUTRIENT; PRIORITY JOURNAL; REVIEW; SURVIVAL RATE;

BRAIN NEOPLASMS; GLIOMA; HETEROCYCLIC COMPOUNDS; HUMANS; MICRONUTRIENTS; NEOPLASM INVASIVENESS;

EID: 0041829262     PISSN: 00016268     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00701-003-0073-7     Document Type: Review

References (57)

1. Agarwal C, Sharma Y, Agarwal R (2000) Anticarcinogenic effect of a polyphenolic fraction isolated from grape seeds in human prostate carcinoma DU145 cells: modulation of mitogenic signaling and cell-cycle regulators and induction of G1 arrest and apoptosis. Mol Carcinogen 28(3): 129-138
2. Bagchi D, Bagchi M, Srohs SJ, Das DK, Ray SD, Kuszynski CA (2000) Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology 148: 187-197
3. Barnes S, Peterson TG, Coward L (1995) Rationale for the use of genistein-containing soy matrices in chemoprevention trials for breast and prostate cancer. J Cell Biochem 22 [Suppl] 1: 181-187
4. Black PM (1991) Brain tumours - part 1. N Engl J Med 324(21): 1471-1476
5. Bracke ME, Depypere HT, Boterberg T, Van Marck VL, Vennekens KM, Vanluchene E, Nuytinck M, Serreyn R, Mareel MM (1999) Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer. J Nat Cancer Inst 91: 355-359
6. Bracke ME, Van Cauwenberge RML, Mareel MM, Castronovo V, Foidart JM (1986) Flavonoids: tools for the study of tumour invasion in vitro plant flavonoids in biology and medicine: biochemical, pharmacological and structure activity relationships. Alan R Liss, Inc., pp 441-444
7. Cao G, Sofic E, Prior RL (1997) Antioxidant and prooxidant behavior of flavonoids: structure activity relationships. Free Radic Biol Med 22: 749-760
8. Carroll KK, Guthrie N, So FV, Chambers AF (1998) Anticancer properties of flavonoids, with emphasis on citrus flavonoids. Flavonoids in health and disease. Marcel Dekker Inc., New York, pp 437-446
9. Clark LC, Combs GF, Turnbull BW, Slate EH, Chalker DK, Chow J, Davis LS, Glover RA, Graham GF, Gross EG, Krongrad A, Lesher JL, Park HK, Sanders BB, Smith CL, Taylor R (1996) Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. JAMA 24: 1957-1963
10. Daley E, Levicar N, Deway R, Wilkie D, Pilkington GJ (submitted) Inhibition of cathepsin L enhances apoptotic response of human glioma cells to clomipramine in vitro
11. Daley E, Bates T, Wilkie D, Pilkington GJ (submitted) Mitochondrial mediation of apoptosis in human brain tumour by clomipramine: a new therapeutic approach
12. Daley E, Aram S, Maidment SL, Wilkie D, Pilkington GJ (submitted) An evaluation of the effects of three tricyclic agents on the growth of human brain tumour cells in vitro
13. Datla KP, Christidou M, Widmer WW, Rooprai HK Dexter DT (2001) Tissue distribution and neuroprotective effects of citrus flavonoid tangeretin in the rat model of Parkinson's disease. NeuroReport 12: 3871-3875
14. Gratsa A, Rooprai HK, Rogers JP, Martin KK, Pilkington GJ (1997) Correlation of expression of NCAM and GD3 ganglioside to motile behaviour in neoplastic glia. Anticancer Res 17: 4111-4118
15. Guthrie N, Carroll KK (1998) Inhibition of mammary cancer by citrus flavonoids. Flavonoids in the living system. Plenum Press, New York, pp 227-236
16. Harborne JB, Baxter H (1999) Handbook of natural flavonoids. 2 vol. Wiley, Chichester
17. Hertog G, Hollman P, Katan M (1992) Content of potentially anti-carcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in Netherlands. J Agric Food Chem 40: 2379-2383
18. Hertog MG, Hollman P, Katan MB, Kromhout D (1993) Intake of potentially anticarcinogenic flavonoids and their determinants in adults in the Netherlands. Nutr Cancer 20: 21-29
19. Hertog MGL, Kromhout D, Aravanis C, Blackburn H, Buzina R, Fidanza F, Giampaoli S, Jansen A, Menotti A, Nedeljkovic S, Pekkarinen M, Simic BS, Toshima H, Feskens E, Hollman PCH, Katan MB (1995) Flavonoid intake and long-term risk of coronary heart disease and cancer in seven countries study. Arch Intern Med 155: 381-386
20. Hughes AR, Wilkie D (1970) Preferential inhibition in Saccharomyces cerevisiae by chlorimipramine. Correlation with chlorpromazine. Biochem Pharmacol 19: 2555-2560
21. Kandaswami C, Perkins E, Drzewiecki G, Soloniuk DS, Middleton E Jr (1992) Differential inhibition of proliferation of human squamous cell carcinoma, gliosarcoma and embryonic fibroblast-like lung cells in culture by plant flavonoids. Anticancer Drugs 3: 505-530
22. Kawaii S, Tomono Y, Katase E, Ogawa K, Yano M (1999) Antiproliferative activity of flavonoids on several cancer cell lines. Biosci Biotechnol Biochem 63: 896-899
23. Khachik F, Beecher GR, Smith JC (1998) Lutein, lycopene and their oxidative metabolites chemoprevention of cancer. J Cell Biochem 22: 236-246
24. Khoshyomn S, Manske GC, Lew SM, Walk SL, Penar PL (2000) Synergistic action of genistein and cisplatin on growth inhibition and cytotoxicity of human medulloblastoma cells. Pediatric Neurosurgery 33(3): 123-131
25. Kyriazis I, Christidou M, Rooprai HK, Davies D, Zicha D, Pilkington GJ (submitted) The effects of Selenium on adhesion, invasion and induction of apoptosis in glioma cells in vitro
26. Levicar N, Daley E, Deway RA, Bates TE, Davies D, Kos J, Pilkington GJ, Lah TT (submitted) Selective suppression of cathepsin L by antisense cDNA impairs human brain tumour cell invasion in vitro and promotes apoptosis
27. Levy J, Bosin E, Feldman B, Giat Y, Minister A (1995) Lycopene is a more potent inhibitor of human cancer cell proliferation than either α-carotene or β-carotene. Nutr Cancer 24: 257-267
28. Libermann TA, Nusbaum HR, Razon N, Kris R, Lax I, Soreq H, Whittle N, Waterfield MD, Ullrich A, Schlessinger J (1985) Amplification and overexpression of the EGF receptor gene in primary human glioblastomas. J Cell Sci - [Suppl] 3: 161-172
29. Lichtor T, Dohrmann GJ, Getz GS (1984) Respiratory deficiency and increased glycolysis in benign human brain tumours. Surg Forum 35: 599-601
30. Linstead D, Wilkie D (1971) A comparative study of in vivo inhibition of mitochondrial function in Saccharomyces cerevisiae by tricyclic and other centrally-acting drugs. Biochem Pharm 20: 839-846
31. Martin PM, Horwitz KB, Ryan DS, McGuire WL (1978) Phytoestrogen interaction with estrogen receptors in human breast cancer cells. Endocrinology 103: 1860-1867
32. Merry S, Hamilton TG, Flanigan P, Freshney RI, Kaye SB (1991) Circumvention of pleiotropic drug resistance in subcutaneous tumours in vivo with verapamil and clomipramine. Eur J Cancer 27: 31-34
33. Merzak A, Koochekpour S, Pilkington GJ (1994) CD44 mediates human glioma cell adhesion and invasion in vitro. Cancer Res 54: 3988-3992
34. Messina MJ, Persky V, Setchell KDR, Barnes S (1994) Soya intake and cancer risk: a review of the in vitro and in vivo data. Nutr Cancer 21: 113-131
35. Middleton E, Kandaswami C (1993) The impact of plant flavonoids on mammalian biology: Implications for immunity, inflammation and cancer. The flavonoids: advances in research since 1986. Chapman and Hall, London, pp 619-645
36. Middleton E Jr, Kandaswami C, Theoharis C, Theoharides (2000) The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease and cancer. Pharmacol Rev 52: 673-751
37. Parker SL, Tong T, Bolden S, Wingo PA (1996) Cancer statistics. CA Cancer J Clin 46: 5-27
38. Penar PL, Khoshyomn S, Bhushan A, Tritton TR (1997) Inhibition of epidermal growth factor receptor associated tyrosine kinase blocks glioblastoma invasion of the brain. Neurosurgery 40: 141-151
39. Peterson J, Dwyer J (1998) Taxonomic classification helps identify flavonoid-containing foods on a semi-quantitative food frequency questionnaire. J Am Diet Assoc 98: 677-682
40. Philipov PH, Tzatchev K (1990) Selenium in the treatment of patients with brain gliomas. Zent Neurochir 51: 145-146
41. Pierpoint WS (1990) PQQ in Plants. Trend Biochem Sci 15: 299
42. Pilkington GJ (1994) Tumour cell migration in the central nervous system. Brain Pathology 4: 157-166
43. Pilkington GJ, Beaney RP, Rooprai HK, Bates T, Daley E, Wilkie D (submitted) The tricyclic clomipramine - a role in the treatment of brain tumours
44. Radhakrishnan K, Bohnen NI, Kurland LT (1993) Epidemiology of brain tumors. In: Morantz RA, Walsh JW (eds) Brain tumours, a comprehensive text. Marcel Dekker, New York, pp 1-18
45. Rahman A, Fazal F, Greensill J, Ainley K, Parish JH, Hadi SM (1992) Strand scission in DNA induced by dietary flavonoids: role of Cu (I) and oxygen free radicals and biological consequence of scission. Mol Cell Biochem 111: 3-9
46. Rooprai HK, Kandanearatchi A, Maidment SL, Christidou M, Trillo-Pazos G, Dexter DT, Rucklidge GJ, Widmer W, Pilkington GJ (2001) Evaluation of the effects of swainsonine, captopril, tangeretin and nobiletin on the biological behaviour of brain tumour cells in vitro. Neuropathol Appl Neurobiol 27: 29-39
47. Sato T, Koike L, Miyata Y, Hirata M, Mimaki Y, Sashida Y, Yano M, Ito A (2002) Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by Nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and -9 in human fibrosarcoma HT-1080 cells. Cancer Res 62: 1025-1029
48. Sengupta A, Das S (1999) The anti-carcinogenic role of lycopene, abundantly present in tomato. Eur J Canc Prevention 8: 325-330
49. Shamberger RJ, Frost DV (1969) Possible protective effects of selenium against human cancer. Can Med Assoc J 100: 468
50. Skibola CF, Smith MT (2000) Potential health impacts of excessive flavonoid intake. Free Radical Biol Med 29: 375-383
51. Steingart AB, Cotterchio M (1995) Do antidepressants cause, promote or inhibit cancers? J Clin Epidemiol 48: 1407-1412
52. Sundaram N, Pahwa AK, Ard MD, Lin N, Perkins E, Bowles AP Jr (2000) Selenium causes growth inhibition and apoptosis in human brain tumour cell lines. J Neuro Oncology 46: 125-133
53. Warburg O (1956) On the origin of cancer cells. Science 123: 309-314
54. Wilkie D (1979) Antimitochondrial drugs in cancer chemotherapy: preliminary communication. JR Soc Med 72: 599-601
55. Wilkie D (1970) Selective inhibition of mitochondrial synthesis in Saccharomyces cerevisiae by canavanine. J Mol Biol 47: 107-113
56. Xia Z, Bergstrand A, DePierre JW, Nassberger L (1999) The antidepressants imipramine, clomipramine and citalopram induce apoptosis in human acute myeloid leukaemia HL-60 cells via caspase 3 activation. J Biochem Molec Toxicol 13: 338-347
57. Zhu Z, Kimura M, Itokawa Y, Nakatsu S, Oda Y, Kikuchi H (1995) The effect of selenium on malignant tumour cells of the brain. Biological trace element research, 49: 1-7