Lupeol induces p53 and cyclin-B-mediated G2/M arrest and targets apoptosis through activation of caspase in mouse skin

Biochemical and Biophysical Research Communications

Volumn 381, Issue 2, 2009, Pages 253-258

  Nigam, Nidhi ^a   Prasad, Sahdeo ^a   George, Jasmine ^a   Shukla, Yogeshwer ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Apoptosis; G2 M arrest; Lupeol; Skin cancer; Swiss albino mouse

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; CASPASE; CASPASE 3; CYCLIN B; CYCLIN DEPENDENT KINASE INHIBITOR 1; DIMETHYLBENZ[A]ANTHRACENE; LUPEOL; PROTEIN P53; SURVIVIN;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BACTERIAL GENE; CELL CYCLE; CELL CYCLE M PHASE; CELL DEGENERATION; CELL MATURATION; CELL MEMBRANE PERMEABILITY; CELL MOTION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOLYSIS; DOWN REGULATION; DRUG EFFECT; DRUG INHIBITION; ELECTRIC POTENTIAL; ENZYME ACTIVATION; EXPERIMENTAL STUDY; FEMALE; GENE EXPRESSION; MEDICINAL PLANT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN; STEM CELL; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CELL DIVISION; CELL PROLIFERATION; CYCLIN B; ENZYME ACTIVATION; G2 PHASE; MICE; MICE, INBRED STRAINS; SKIN; SKIN NEOPLASMS; TRANSCRIPTION, GENETIC; TRITERPENES; TUMOR SUPPRESSOR PROTEIN P53;

MUS;

EID: 61849102896     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.02.033     Document Type: Article

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