메뉴 건너뛰기




Volumn 23, Issue 1 A, 2003, Pages 363-398

Anticancer potential of curcumin: Preclinical and clinical studies

Author keywords

Anticancer agents; AP 1; Chemopreventive agents; COX 2; Curcumin; Cyclin D1; NF KB

Indexed keywords

CHEMOKINE; CORTICOSTEROID; CURCUMIN; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE B; LIPOXYGENASE; NITRIC OXIDE SYNTHASE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR; UROKINASE;

EID: 0037236792     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (2486)

References (337)
  • 1
    • 0014884379 scopus 로고
    • Effect of curcumin on serum and liver cholesterol levels in the rat
    • Rao DS, Sekhara NC, Satyanarayana MN and Srinivasan M: Effect of curcumin on serum and liver cholesterol levels in the rat. J Nutr 100: 1307-15, 1970.
    • (1970) J Nutr , vol.100 , pp. 1307-1315
    • Rao, D.S.1    Sekhara, N.C.2    Satyanarayana, M.N.3    Srinivasan, M.4
  • 2
    • 0015047333 scopus 로고
    • Hypocholesteremic effect of curcumin in induced hypercholesteremic rats
    • Patil TN and Srinivasan M: Hypocholesteremic effect of curcumin in induced hypercholesteremic rats. Indian J Exp Biol 9: 167-9, 1971.
    • (1971) Indian J Exp Biol , vol.9 , pp. 167-169
    • Patil, T.N.1    Srinivasan, M.2
  • 3
    • 0016955221 scopus 로고
    • The influence of turmeric and curcumin on cholesterol concentration of eggs and tissues
    • Keshavarz K: The influence of turmeric and curcumin on cholesterol concentration of eggs and tissues. Poult Sci 55: 1077-83, 1976.
    • (1976) Poult Sci , vol.55 , pp. 1077-1083
    • Keshavarz, K.1
  • 5
    • 0027080521 scopus 로고
    • Effect of oral curcumin administration on serum peroxides and cholesterol levels in human volunteers
    • Soni KB and Kuttan R: Effect of oral curcumin administration on serum peroxides and cholesterol levels in human volunteers. Indian J Physiol Pharmacol 36: 273-5, 1992.
    • (1992) Indian J Physiol Pharmacol , vol.36 , pp. 273-275
    • Soni, K.B.1    Kuttan, R.2
  • 6
    • 0027064932 scopus 로고
    • Effect on curcumin on cholesterol gall-stone induction in mice
    • Hussain MS and Chandrasekhara N: Effect on curcumin on cholesterol gall-stone induction in mice. Indian J Med Res 96: 288-91, 1992.
    • (1992) Indian J Med Res , vol.96 , pp. 288-291
    • Hussain, M.S.1    Chandrasekhara, N.2
  • 7
    • 0035171859 scopus 로고    scopus 로고
    • Dietary curcuminoids prevent high-fat diet-induced lipid accumulation in rat liver and epididymal adipose tissue
    • Asai A and Miyazawa T: Dietary curcuminoids prevent high-fat diet-induced lipid accumulation in rat liver and epididymal adipose tissue. J Nutr 131: 2932-5, 2001.
    • (2001) J Nutr , vol.131 , pp. 2932-2935
    • Asai, A.1    Miyazawa, T.2
  • 9
    • 0036191276 scopus 로고    scopus 로고
    • Inhibition of human low density lipoprotein oxidation by active principles from spices
    • Naidu KA and Thippeswamy NB: Inhibition of human low density lipoprotein oxidation by active principles from spices. Mol Cell Biochem 229: 19-23, 2002.
    • (2002) Mol Cell Biochem , vol.229 , pp. 19-23
    • Naidu, K.A.1    Thippeswamy, N.B.2
  • 10
    • 0037007177 scopus 로고    scopus 로고
    • Protective activities of some phenolic 1,3-diketones against lipid peroxidation: Possible involvement of the 1,3-diketone moiety
    • Patro BS, Rele S, Chintalwar GJ, Chattopadhyay S, Adhikari S and Mukherjee T: Protective activities of some phenolic 1,3-diketones against lipid peroxidation: possible involvement of the 1,3-diketone moiety. Chembiochem 3: 364-70, 2002.
    • (2002) Chembiochem , vol.3 , pp. 364-370
    • Patro, B.S.1    Rele, S.2    Chintalwar, G.J.3    Chattopadhyay, S.4    Adhikari, S.5    Mukherjee, T.6
  • 11
    • 0022634112 scopus 로고
    • Effect of curcumin on platelet aggregation and vascular prostacyclin synthesis
    • Srivastava R, Puri V, Srimal RC and Dhawan BN: Effect of curcumin on platelet aggregation and vascular prostacyclin synthesis. Arzneimittelforschung 36: 715-7, 1986.
    • (1986) Arzneimittelforschung , vol.36 , pp. 715-717
    • Srivastava, R.1    Puri, V.2    Srimal, R.C.3    Dhawan, B.N.4
  • 12
    • 0028957622 scopus 로고
    • Curcumin, a major component of food spice turmeric (Curcuma longa) inhibits aggregation and alters eicosanoid metabolism in human blood platelets
    • Srivastava KC, Bordia A and Verma SK: Curcumin, a major component of food spice turmeric (Curcuma longa) inhibits aggregation and alters eicosanoid metabolism in human blood platelets. Prostaglandins Leukot Essent Fatty Acids 52: 223-7, 1995.
    • (1995) Prostaglandins Leukot Essent Fatty Acids , vol.52 , pp. 223-227
    • Srivastava, K.C.1    Bordia, A.2    Verma, S.K.3
  • 14
    • 0028887709 scopus 로고
    • Prevention of ischaemia-induced biochemical changes by curcumin & quinidine in the cat heart
    • Dikshit M, Rastogi L, Shukla R and Srimal RC: Prevention of ischaemia-induced biochemical changes by curcumin & quinidine in the cat heart. Indian J Med Res 101: 31-5, 1995.
    • (1995) Indian J Med Res , vol.101 , pp. 31-35
    • Dikshit, M.1    Rastogi, L.2    Shukla, R.3    Srimal, R.C.4
  • 15
    • 0030045859 scopus 로고    scopus 로고
    • Effect of curcumin on certain lysosomal hydrolases in isoproterenol-induced myocardial infarction in rats
    • Nirmala C and Puvanakrishnan R: Effect of curcumin on certain lysosomal hydrolases in isoproterenol-induced myocardial infarction in rats. Biochem Pharmacol 51: 47-51, 1996.
    • (1996) Biochem Pharmacol , vol.51 , pp. 47-51
    • Nirmala, C.1    Puvanakrishnan, R.2
  • 16
    • 0030002254 scopus 로고    scopus 로고
    • Protective role of curcumin against isoproterenol induced myocardial infarction in rats
    • Nirmala C and Puvanakrishnan R: Protective role of curcumin against isoproterenol induced myocardial infarction in rats. Mol Cell Biochem 159: 85-93, 1996.
    • (1996) Mol Cell Biochem , vol.159 , pp. 85-93
    • Nirmala, C.1    Puvanakrishnan, R.2
  • 17
    • 0031801988 scopus 로고    scopus 로고
    • Curcumin attenuation of acute adriamycin myocardial toxicity in rats
    • Venkatesan N: curcumin attenuation of acute adriamycin myocardial toxicity in rats. Br J Pharmacol 124: 425-7, 1998.
    • (1998) Br J Pharmacol , vol.124 , pp. 425-427
    • Venkatesan, N.1
  • 18
    • 0015319846 scopus 로고
    • Effect of curcumin on blood sugar as seen in a diabetic subject
    • Srinivasan M: Effect of curcumin on blood sugar as seen in a diabetic subject. Indian J Med Sci 26: 269-70, 1972.
    • (1972) Indian J Med Sci , vol.26 , pp. 269-270
    • Srinivasan, M.1
  • 19
    • 0028807262 scopus 로고
    • Influence of dietary curcumin and cholesterol on the progression of experimentally induced diabetes in albino rat
    • Babu PS and Srinivasan K: Influence of dietary curcumin and cholesterol on the progression of experimentally induced diabetes in albino rat. Mol Cell Biochem 152: 13-21, 1995.
    • (1995) Mol Cell Biochem , vol.152 , pp. 13-21
    • Babu, P.S.1    Srinivasan, K.2
  • 20
    • 8044223405 scopus 로고    scopus 로고
    • Hypolipidernic action of curcumin, the active principle of turmeric (Curcuma longa) in streptozotocin induced diabetic rats
    • Babu PS and Srinivasan K: Hypolipidernic action of curcumin, the active principle of turmeric (Curcuma longa) in streptozotocin induced diabetic rats. Mol Cell Biochem 166: 169-75, 1997.
    • (1997) Mol Cell Biochem , vol.166 , pp. 169-175
    • Babu, P.S.1    Srinivasan, K.2
  • 21
    • 0031883154 scopus 로고    scopus 로고
    • Amelioration of renal lesions associated with diabetes by dietary curcumin in streptozotocin diabetic rats
    • Suresh Babu P and Srinivasan K: Amelioration of renal lesions associated with diabetes by dietary curcumin in streptozotocin diabetic rats. Mol Cell Biochem 181: 87-96, 1998.
    • (1998) Mol Cell Biochem , vol.181 , pp. 87-96
    • Suresh Babu, P.1    Srinivasan, K.2
  • 22
    • 0036007614 scopus 로고    scopus 로고
    • Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats
    • Arun N and Nalini N: Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats. Plant Foods Hum Nutr 57: 41-52, 2002.
    • (2002) Plant Foods Hum Nutr , vol.57 , pp. 41-52
    • Arun, N.1    Nalini, N.2
  • 23
    • 0018887037 scopus 로고
    • Preliminary study on antirheumatic activity of curcumin (diferuloyl methane)
    • Deodhar SD, Sethi R and Srimal RC: Preliminary study on antirheumatic activity of curcumin (diferuloyl methane). Indian J Med Res 71: 632-4, 1980.
    • (1980) Indian J Med Res , vol.71 , pp. 632-634
    • Deodhar, S.D.1    Sethi, R.2    Srimal, R.C.3
  • 24
    • 0037097660 scopus 로고    scopus 로고
    • Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes
    • Natarajan C and Bright JJ: Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes. J Immunol 168: 6506-13, 2002.
    • (2002) J Immunol , vol.168 , pp. 6506-6513
    • Natarajan, C.1    Bright, J.J.2
  • 25
    • 0035503597 scopus 로고    scopus 로고
    • The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
    • Lim GP, Chu T, Yang F, Beech W, Frautschy SA and Cole GM: The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci 21: 8370-7, 2001.
    • (2001) J Neurosci , vol.21 , pp. 8370-8377
    • Lim, G.P.1    Chu, T.2    Yang, F.3    Beech, W.4    Frautschy, S.A.5    Cole, G.M.6
  • 26
    • 0035686083 scopus 로고    scopus 로고
    • Phenolic anti-inflammatory antioxidant reversal of a beta-induced cognitive deficits and neuropathology
    • Frautschy SA, Hu W, Kim P, Miller SA, Chu T, Harris-White ME and Cole GM: Phenolic anti-inflammatory antioxidant reversal of a beta-induced cognitive deficits and neuropathology. Neurobiol Aging 22: 993-1005, 2001.
    • (2001) Neurobiol Aging , vol.22 , pp. 993-1005
    • Frautschy, S.A.1    Hu, W.2    Kim, P.3    Miller, S.A.4    Chu, T.5    Harris-White, M.E.6    Cole, G.M.7
  • 27
    • 0027792308 scopus 로고
    • Inhibition of the HIV-1 and HIV-2 proteases by curcumin and curcumin boron complexes
    • Sui Z, Salto R, Li J, Craik C and Ortiz de Montellano PR: Inhibition of the HIV-1 and HIV-2 proteases by curcumin and curcumin boron complexes. Bioorg Med Chem 1: 415-22, 1993.
    • (1993) Bioorg Med Chem , vol.1 , pp. 415-422
    • Sui, Z.1    Salto, R.2    Li, J.3    Craik, C.4    Ortiz De Montellano, P.R.5
  • 28
    • 0027403716 scopus 로고
    • Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication
    • Li CJ, Zhang LJ, Dezube BJ, Crumpacker CS and Pardee AB: Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication. Proc Natl Acad Sci USA 90: 1839-42, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1839-1842
    • Li, C.J.1    Zhang, L.J.2    Dezube, B.J.3    Crumpacker, C.S.4    Pardee, A.B.5
  • 29
    • 0030163810 scopus 로고    scopus 로고
    • Curcumin - A natural herb with anti-HIV activity
    • Jordan WC and Drew CR: Curcumin - a natural herb with anti-HIV activity. J Natl Med Assoc 88: 333, 1996.
    • (1996) J Natl Med Assoc , vol.88 , pp. 333
    • Jordan, W.C.1    Drew, C.R.2
  • 30
    • 0030805998 scopus 로고    scopus 로고
    • Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action
    • Mazumder A, Nearnati N, Sunder S, Schulz J, Pertz H, Eich E and Pommier Y: curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action. J Med Chem 40: 3057-63, 1997.
    • (1997) J Med Chem , vol.40 , pp. 3057-3063
    • Mazumder, A.1    Nearnati, N.2    Sunder, S.3    Schulz, J.4    Pertz, H.5    Eich, E.6    Pommier, Y.7
  • 31
    • 0031976901 scopus 로고    scopus 로고
    • Curcumin and curcumin derivatives inhibit Tat-mediated transactivation of type 1 human immunodeficiency virus long terminal repeat
    • Barthelemy S, Vergnes L, Moynier M, Guyot D, Labidalle S and Bahraoui E: Curcumin and curcumin derivatives inhibit Tat-mediated transactivation of type 1 human immunodeficiency virus long terminal repeat. Res Virol 149: 43-52, 1998.
    • (1998) Res Virol , vol.149 , pp. 43-52
    • Barthelemy, S.1    Vergnes, L.2    Moynier, M.3    Guyot, D.4    Labidalle, S.5    Bahraoui, E.6
  • 33
    • 0035212813 scopus 로고    scopus 로고
    • Protective effects of curcumin against oxidative damage on skin cells in vitro: Its implication for wound healing
    • Phan TT, See P, Lee ST and Chan SY: Protective effects of curcumin against oxidative damage on skin cells in vitro: its implication for wound healing. J Trauma 51: 927-31, 2001.
    • (2001) J Trauma , vol.51 , pp. 927-931
    • Phan, T.T.1    See, P.2    Lee, S.T.3    Chan, S.Y.4
  • 34
    • 0034874170 scopus 로고    scopus 로고
    • Quercetin and curcumin upregulate antioxidant gene expression in rat kidney after ureteral obstruction or ischemia/reperfusion injury
    • Shahed AR, Jones E and Shoskes D: Quercetin and curcumin upregulate antioxidant gene expression in rat kidney after ureteral obstruction or ischemia/reperfusion injury. Transplant Proc 33: 2988, 2001.
    • (2001) Transplant Proc , vol.33 , pp. 2988
    • Shahed, A.R.1    Jones, E.2    Shoskes, D.3
  • 35
    • 0036583502 scopus 로고    scopus 로고
    • Medicinal foodstuffs. XXIX. Potent protective effects of sesquiterpenes and curcumin from Zedoariae Rhizoma on liver injury induced by D-galactosamine/lipopolysaccharide or tumor necrosis factor-alpha
    • Morikawa T, Matsuda H, Ninomiya K and Yoshikawa M: Medicinal foodstuffs. XXIX. Potent protective effects of sesquiterpenes and curcumin from Zedoariae Rhizoma on liver injury induced by D-galactosamine/lipopolysaccharide or tumor necrosis factor-alpha. Biol Pharm Bull 25: 627-31, 2002.
    • (2002) Biol Pharm Bull , vol.25 , pp. 627-631
    • Morikawa, T.1    Matsuda, H.2    Ninomiya, K.3    Yoshikawa, M.4
  • 36
    • 0000064941 scopus 로고
    • Studies on Indian medicinal plants: Curcuma longa Linn. - Effect of curcumin & the essential oils of C. longa on bile secretion
    • Ramprasad C and Sirsi M: Studies on Indian medicinal plants: Curcuma longa Linn.- effect of curcumin & the essential oils of C. longa on bile secretion. J Sci Industr Res 15: 262-265, 1956.
    • (1956) J Sci Industr Res , vol.15 , pp. 262-265
    • Ramprasad, C.1    Sirsi, M.2
  • 38
    • 0028955691 scopus 로고
    • Modulation of cyclophosphamide-induced early lung injury by curcumin, an anti-inflammatory antioxidant
    • Venkatesan N and Chandrakasan G: Modulation of cyclophosphamide-induced early lung injury by curcumin, an anti-inflammatory antioxidant. Mol Cell Biochem 142: 79-87, 1995.
    • (1995) Mol Cell Biochem , vol.142 , pp. 79-87
    • Venkatesan, N.1    Chandrakasan, G.2
  • 39
  • 40
    • 17644445641 scopus 로고    scopus 로고
    • Pulmonary protective effects of curcumin against paraquat toxicity
    • Venkatesan N: Pulmonary protective effects of curcumin against paraquat toxicity. Life Sci 66: PL21-8, 2000.
    • (2000) Life Sci , vol.66
    • Venkatesan, N.1
  • 41
    • 0033778209 scopus 로고    scopus 로고
    • Curcumin inhibition of bleomycin-induced pulmonary fibrosis in rats
    • Punithavathi D, Venkatesan N and Babu M: Curcumin inhibition of bleomycin-induced pulmonary fibrosis in rats. Br J Pharmacol 131: 169-72, 2000.
    • (2000) Br J Pharmacol , vol.131 , pp. 169-172
    • Punithavathi, D.1    Venkatesan, N.2    Babu, M.3
  • 45
    • 0026657246 scopus 로고
    • Inhibitory effect of curcumin, an anti-inflammatory agent, on vascular smooth muscle cell proliferation
    • Huang HC, Jan TR and Yeh SF: Inhibitory effect of curcumin, an anti-inflammatory agent, on vascular smooth muscle cell proliferation. Eur J Pharmacol 221: 381-4, 1992.
    • (1992) Eur J Pharmacol , vol.221 , pp. 381-384
    • Huang, H.C.1    Jan, T.R.2    Yeh, S.F.3
  • 46
    • 0031826446 scopus 로고    scopus 로고
    • Effect of curcumin on cell cycle progression and apoptosis in vascular smooth muscle cells
    • Chen HW and Huang HC: Effect of curcumin on cell cycle progression and apoptosis in vascular smooth muscle cells. Br J Pharmacol 124: 1029-40, 1998.
    • (1998) Br J Pharmacol , vol.124 , pp. 1029-1040
    • Chen, H.W.1    Huang, H.C.2
  • 47
    • 0015785965 scopus 로고
    • Pharmacology of diferuloylmethane (curcumin), a non-steroidal anti-inflammatory agent
    • Srimal RC and Dhawan BN: Pharmacology of diferuloylmethane (curcumin), a non-steroidal anti-inflammatory agent. J Pharm Pharmacol 25: 447-52, 1973.
    • (1973) J Pharm Pharmacol , vol.25 , pp. 447-452
    • Srimal, R.C.1    Dhawan, B.N.2
  • 48
    • 0026051398 scopus 로고
    • Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin
    • Conney AH, Lysz T, Ferraro T, Abidi TF, Manchand PS, Laskin JD and Huang MT: Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin. Adv Enzyme Regul 31: 385-96, 1991.
    • (1991) Adv Enzyme Regul , vol.31 , pp. 385-396
    • Conney, A.H.1    Lysz, T.2    Ferraro, T.3    Abidi, T.F.4    Manchand, P.S.5    Laskin, J.D.6    Huang, M.T.7
  • 50
    • 0036279287 scopus 로고    scopus 로고
    • Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: A short review
    • Surh YJ: Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review. Food Chem Toxicol 40: 1091-7, 2002.
    • (2002) Food Chem Toxicol , vol.40 , pp. 1091-1097
    • Surh, Y.J.1
  • 51
    • 0036217821 scopus 로고    scopus 로고
    • Natural products as targeted modulators of the nuclear factor-kappaB pathway
    • Bremner P and Heinrich M: Natural products as targeted modulators of the nuclear factor-kappaB pathway. J Pharm Pharmacol 54: 453-72, 2002.
    • (2002) J Pharm Pharmacol , vol.54 , pp. 453-472
    • Bremner, P.1    Heinrich, M.2
  • 52
    • 0035383229 scopus 로고    scopus 로고
    • Cancer chemoprevention by dietary constituents: A tale of failure and promise
    • Gescher AJ, Sharma RA and Steward WP: Cancer chemoprevention by dietary constituents: a tale of failure and promise. Lancet Oncol 2: 371-9, 2001.
    • (2001) Lancet Oncol , vol.2 , pp. 371-379
    • Gescher, A.J.1    Sharma, R.A.2    Steward, W.P.3
  • 54
    • 0036302071 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane), a singlet oxygen ((1)0(2)) quencher
    • Das KC and Das CK: curcumin (diferuloylmethane), a singlet oxygen ((1)0(2)) quencher. Biochem Biophys Res Commun 295: 62-6, 2002.
    • (2002) Biochem Biophys Res Commun , vol.295 , pp. 62-66
    • Das, K.C.1    Das, C.K.2
  • 57
    • 0022066944 scopus 로고
    • Studies on curcumin and curcuminoids. VI. Kinetics of curcumin degradation in aqueous solution
    • Tonnesen HH and Karlsen J: Studies on curcumin and curcuminoids. VI. Kinetics of curcumin degradation in aqueous solution. Z Lebensm Unters Forsch 180: 402-4, 1985.
    • (1985) Z Lebensm Unters Forsch , vol.180 , pp. 402-404
    • Tonnesen, H.H.1    Karlsen, J.2
  • 58
    • 0022764965 scopus 로고
    • Studies on curcumin and curcuminoids. VIII. Photochemical stability of curcumin
    • Tonnesen HH, Karlsen J and van Henegouwen GB: Studies on curcumin and curcuminoids. VIII. Photochemical stability of curcumin. Z Lebensm Unters Forsch 183: 116-22, 1986.
    • (1986) Z Lebensm Unters Forsch , vol.183 , pp. 116-122
    • Tonnesen, H.H.1    Karlsen, J.2    Van Henegouwen, G.B.3
  • 59
    • 0023183657 scopus 로고
    • Studies on curcumin and curcuminoids. IX: Investigation of the photobiological activity of curcumin using bacterial indicator systems
    • Tonnesen HH, de Vries H, Karlsen J and Beijersbergen van Henegouwen G: Studies on curcumin and curcuminoids. IX: Investigation of the photobiological activity of curcumin using bacterial indicator systems. J Pharm Sci 76: 371-3, 1987.
    • (1987) J Pharm Sci , vol.76 , pp. 371-373
    • Tonnesen, H.H.1    De Vries, H.2    Karlsen, J.3    Beijersbergen Van Henegouwen, G.4
  • 60
    • 0037026270 scopus 로고    scopus 로고
    • Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: Solubility, chemical and photochemical stability
    • Tonnesen H, Masson M and Loftsson T: Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: solubility, chemical and photochemical stability. Int J Pharm 244: 127, 2002.
    • (2002) Int J Pharm , vol.244 , pp. 127
    • Tonnesen, H.1    Masson, M.2    Loftsson, T.3
  • 62
    • 0030476104 scopus 로고    scopus 로고
    • Induction of HSP70 gene expression by modulation of Ca(+2) ion and cellular p53 protein by curcumin in colorectal carcinoma cells
    • Chen YC, Kuo TC, Lin-Shiau SY and Lin JK: Induction of HSP70 gene expression by modulation of Ca(+2) ion and cellular p53 protein by curcumin in colorectal carcinoma cells. Mol Carcinog 17: 224-34, 1996.
    • (1996) Mol Carcinog , vol.17 , pp. 224-234
    • Chen, Y.C.1    Kuo, T.C.2    Lin-Shiau, S.Y.3    Lin, J.K.4
  • 63
    • 0029757364 scopus 로고    scopus 로고
    • Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines
    • Jiang MC, Yang-Yen HF, Yen JJ and Lin JK: Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines. Nutr Cancer 26: 111-20, 1996.
    • (1996) Nutr Cancer , vol.26 , pp. 111-120
    • Jiang, M.C.1    Yang-Yen, H.F.2    Yen, J.J.3    Lin, J.K.4
  • 64
    • 0030589131 scopus 로고    scopus 로고
    • Curcumin, an antioxidant and anti-tumor promoter, induces apoptosis in human leukemia cells
    • Kuo ML, Huang TS and Lin JK: Curcumin, an antioxidant and anti-tumor promoter, induces apoptosis in human leukemia cells. Biochim Biophys Acta 1317: 95-100, 1996.
    • (1996) Biochim Biophys Acta , vol.1317 , pp. 95-100
    • Kuo, M.L.1    Huang, T.S.2    Lin, J.K.3
  • 65
    • 0030872976 scopus 로고    scopus 로고
    • Antiproliferative effect of curcumin (diferuloylmethane) against human breast tumor cell lines
    • Mehta F, Pantazis P, McQueen T and Aggarwal BB: Antiproliferative effect of curcumin (diferuloylmethane) against human breast tumor cell lines. Anticancer Drugs 8: 470-81, 1997.
    • (1997) Anticancer Drugs , vol.8 , pp. 470-481
    • Mehta, F.1    Pantazis, P.2    McQueen, T.3    Aggarwal, B.B.4
  • 66
    • 0031589212 scopus 로고    scopus 로고
    • Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides
    • Verma SP, Salamone E and Goldin B: Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides. Biochem Biophys Res Commun 233: 692-6, 1997.
    • (1997) Biochem Biophys Res Commun , vol.233 , pp. 692-696
    • Verma, S.P.1    Salamone, E.2    Goldin, B.3
  • 67
    • 0031460545 scopus 로고    scopus 로고
    • Curcumin, a natural plant phenolic food additive, inhibits cell proliferation and induces cell cycle changes in colon adenocarcinoma cell lines by a prostaglandin-independent pathway
    • Hanif R, Qiao L, Shiff SJ and Rigas B: Curcumin, a natural plant phenolic food additive, inhibits cell proliferation and induces cell cycle changes in colon adenocarcinoma cell lines by a prostaglandin-independent pathway. J Lab Clin Med 130: 576-84, 1997.
    • (1997) J Lab Clin Med , vol.130 , pp. 576-584
    • Hanif, R.1    Qiao, L.2    Shiff, S.J.3    Rigas, B.4
  • 68
    • 0031000902 scopus 로고    scopus 로고
    • Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: Apoptotic index as a biomarker in colon cancer chemoprevention and promotion
    • Samaha HS, Kelloff GJ, Steele V, Rao CV and Reddy BS: Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion. Cancer Res 57: 1301-5, 1997.
    • (1997) Cancer Res , vol.57 , pp. 1301-1305
    • Samaha, H.S.1    Kelloff, G.J.2    Steele, V.3    Rao, C.V.4    Reddy, B.S.5
  • 69
    • 0032479574 scopus 로고    scopus 로고
    • Inhibitory effect of curcuminoids on MCF-7 cell proliferation and structure-activity relationships
    • Simon A, Allais DP, Duroux JL, Basly JP, Durand-Fontanier S and Delage C: Inhibitory effect of curcuminoids on MCF-7 cell proliferation and structure-activity relationships. Cancer Lett 129: 111-6, 1998.
    • (1998) Cancer Lett , vol.129 , pp. 111-116
    • Simon, A.1    Allais, D.P.2    Duroux, J.L.3    Basly, J.P.4    Durand-Fontanier, S.5    Delage, C.6
  • 70
    • 0031716184 scopus 로고    scopus 로고
    • Curcumin induces a p53-dependent apoptosis in human basal cell carcinoma cells
    • Jee SH, Shen SC, Tseng CR, Chiu HC and Kuo ML: Curcumin induces a p53-dependent apoptosis in human basal cell carcinoma cells. J Invest Dermatol 111: 656-61, 1998.
    • (1998) J Invest Dermatol , vol.111 , pp. 656-661
    • Jee, S.H.1    Shen, S.C.2    Tseng, C.R.3    Chiu, H.C.4    Kuo, M.L.5
  • 72
    • 0033563646 scopus 로고    scopus 로고
    • A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by curcumin in human lymphoblastoid T (Jurkat) cells
    • Piwocka K, Zablocki K, Wieckowski MR, Skierski J, Feiga I, Szopa J, Drela N, Wojtczak L and Sikora E: A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by curcumin in human lymphoblastoid T (Jurkat) cells. Exp Cell Res 249: 299-307, 1999.
    • (1999) Exp Cell Res , vol.249 , pp. 299-307
    • Piwocka, K.1    Zablocki, K.2    Wieckowski, M.R.3    Skierski, J.4    Feiga, I.5    Szopa, J.6    Drela, N.7    Wojtczak, L.8    Sikora, E.9
  • 73
    • 0033064548 scopus 로고    scopus 로고
    • Antitumor activity of curcumin is mediated through the induction of apoptosis in AK-5 tumor cells
    • Khar A, Ali AM, Pardhasaradhi BV, Begum Z and Anjum R: Antitumor activity of curcumin is mediated through the induction of apoptosis in AK-5 tumor cells. FEBS Lett 445: 165-8, 1999.
    • (1999) FEBS Lett , vol.445 , pp. 165-168
    • Khar, A.1    Ali, A.M.2    Pardhasaradhi, B.V.3    Begum, Z.4    Anjum, R.5
  • 74
    • 0032743140 scopus 로고    scopus 로고
    • Curcumin causes the growth arrest and apoptosis of B cell lymphoma by downregulation of egr-1, c-myc, bcl-XL, NF-kappa B, and p53
    • Han SS, Chung ST, Robertson DA, Ranjan D and Bondada S: Curcumin causes the growth arrest and apoptosis of B cell lymphoma by downregulation of egr-1, c-myc, bcl-XL, NF-kappa B, and p53. Clin Immunol 93: 152-61, 1999.
    • (1999) Clin Immunol , vol.93 , pp. 152-161
    • Han, S.S.1    Chung, S.T.2    Robertson, D.A.3    Ranjan, D.4    Bondada, S.5
  • 75
    • 0032998883 scopus 로고    scopus 로고
    • Differential sensitivity of human mammary epithelial and breast carcinoma cell lines to curcumin
    • Ramachandran C and You W: Differential sensitivity of human mammary epithelial and breast carcinoma cell lines to curcumin. Breast Cancer Res Treat 54: 269-78, 1999.
    • (1999) Breast Cancer Res Treat , vol.54 , pp. 269-278
    • Ramachandran, C.1    You, W.2
  • 76
    • 0032763091 scopus 로고    scopus 로고
    • Curcumin inhibits cell proliferation by interfering with the cell cycle and inducing apoptosis in colon carcinoma cells
    • Chen H, Zhang ZS, Zhang YL and Zhou DY: Curcumin inhibits cell proliferation by interfering with the cell cycle and inducing apoptosis in colon carcinoma cells. Anticancer Res 19: 3675-80, 1999.
    • (1999) Anticancer Res , vol.19 , pp. 3675-3680
    • Chen, H.1    Zhang, Z.S.2    Zhang, Y.L.3    Zhou, D.Y.4
  • 77
    • 0032815637 scopus 로고    scopus 로고
    • Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates
    • Bhaumik S, Anjum R, Rangaraj N, Pardhasaradhi BV and Khar A: Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates. FEBS Lett 456: 311-4, 1999.
    • (1999) FEBS Lett , vol.456 , pp. 311-314
    • Bhaumik, S.1    Anjum, R.2    Rangaraj, N.3    Pardhasaradhi, B.V.4    Khar, A.5
  • 78
    • 0033856514 scopus 로고    scopus 로고
    • The inhibitory effect of curcumin, genistein, quercetin and cisplatin on the growth of oral cancer cells in vitro
    • Elattar TM and Virji AS: The inhibitory effect of curcumin, genistein, quercetin and cisplatin on the growth of oral cancer cells in vitro. Anticancer Res 20: 1733-8, 2000.
    • (2000) Anticancer Res , vol.20 , pp. 1733-1738
    • Elattar, T.M.1    Virji, A.S.2
  • 80
    • 0035884995 scopus 로고    scopus 로고
    • Curcumin inhibits activation of Vgamma9Vdelta2 T cells by phosphoantigens and induces apoptosis involving apoptosis-inducing factor and large scale DNA fragmentation
    • Cipriani B, Borsellino G, Knowles H, Tramonti D, Cavaliere F, Bernardi G, Battistini L and Brosnan CF: Curcumin inhibits activation of Vgamma9Vdelta2 T cells by phosphoantigens and induces apoptosis involving apoptosis-inducing factor and large scale DNA fragmentation. J Immunol 167: 3454-62, 2001.
    • (2001) J Immunol , vol.167 , pp. 3454-3462
    • Cipriani, B.1    Borsellino, G.2    Knowles, H.3    Tramonti, D.4    Cavaliere, F.5    Bernardi, G.6    Battistini, L.7    Brosnan, C.F.8
  • 81
    • 0034836540 scopus 로고    scopus 로고
    • Induction of apoptosis by garcinol and curcumin through cytochrome c release and activation of caspases in human leukemia HL-60 cells
    • Pan MH, Chang WL, Lin-Shiau SY, Ho CT, Lin JK: Induction of apoptosis by garcinol and curcumin through cytochrome c release and activation of caspases in human leukemia HL-60 cells. J Agric Food Chem 49: 1464-74, 2001.
    • (2001) J Agric Food Chem , vol.49 , pp. 1464-1474
    • Pan, M.H.1    Chang, W.L.2    Lin-Shiau, S.Y.3    Ho, C.T.4    Lin, J.K.5
  • 82
    • 0035917844 scopus 로고    scopus 로고
    • Curcumin induces the mitochondrial permeability transition pore mediated by membrane protein thiol oxidation
    • Morin D, Barthelemy S, Zini R, Labidalle S and Tillement JP: Curcumin induces the mitochondrial permeability transition pore mediated by membrane protein thiol oxidation. FEBS Lett 495: 131-6, 2001.
    • (2001) FEBS Lett , vol.495 , pp. 131-136
    • Morin, D.1    Barthelemy, S.2    Zini, R.3    Labidalle, S.4    Tillement, J.P.5
  • 83
    • 0035002201 scopus 로고    scopus 로고
    • Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells
    • Moragoda L, Jaszewski R and Majumdar AP: Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells. Anticancer Res 21: 873-8, 2001.
    • (2001) Anticancer Res , vol.21 , pp. 873-878
    • Moragoda, L.1    Jaszewski, R.2    Majumdar, A.P.3
  • 84
    • 0035891055 scopus 로고    scopus 로고
    • Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines
    • Mukhopadhyay A, Bueso-Ramos C, Chatterjee D, Pantazis P and Aggarwal BB: Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines. Oncogene 20: 7597-609, 2001.
    • (2001) Oncogene , vol.20 , pp. 7597-7609
    • Mukhopadhyay, A.1    Bueso-Ramos, C.2    Chatterjee, D.3    Pantazis, P.4    Aggarwal, B.B.5
  • 86
    • 0035434001 scopus 로고    scopus 로고
    • Inhibition of invasion and induction of apoptosis by curcumin in H-ras-transformed MCF 10A human breast epithelial cells
    • Kim MS, Kang HJ and Moon A: Inhibition of invasion and induction of apoptosis by curcumin in H-ras-transformed MCF10A human breast epithelial cells. Arch Pharm Res 24: 349-54, 2001.
    • (2001) Arch Pharm Res , vol.24 , pp. 349-354
    • Kim, M.S.1    Kang, H.J.2    Moon, A.3
  • 87
    • 0035451195 scopus 로고    scopus 로고
    • Effect of glutathione depletion on caspase-3 independent apoptosis pathway induced by curcumin in Jurkat cells
    • Piwocka K, Jaruga E, Skierski J, Gradzka I and Sikora E: Effect of glutathione depletion on caspase-3 independent apoptosis pathway induced by curcumin in Jurkat cells. Free Radic Biol Med 31: 670-8, 2001.
    • (2001) Free Radic Biol Med , vol.31 , pp. 670-678
    • Piwocka, K.1    Jaruga, E.2    Skierski, J.3    Gradzka, I.4    Sikora, E.5
  • 88
    • 0035842333 scopus 로고    scopus 로고
    • Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53
    • Bush JA, Cheung KJ, Jr. and Li G: Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53. Exp Cell Res 271: 305-14, 2001.
    • (2001) Exp Cell Res , vol.271 , pp. 305-314
    • Bush, J.A.1    Cheung K.J., Jr.2    Li, G.3
  • 89
    • 0035451496 scopus 로고    scopus 로고
    • Cell proliferation in cancer prevention; effects of preventive agents on estrogen-related endometrial carcinogenesis model and on an in vitro model in human colorectal cells
    • Mori H, Niwa K, Zheng Q, Yamada Y, Sakata K and Yoshimi N: Cell proliferation in cancer prevention; effects of preventive agents on estrogen-related endometrial carcinogenesis model and on an in vitro model in human colorectal cells. Mutat Res 480-481: 201-7, 2001.
    • (2001) Mutat Res , vol.480-481 , pp. 201-207
    • Mori, H.1    Niwa, K.2    Zheng, Q.3    Yamada, Y.4    Sakata, K.5    Yoshimi, N.6
  • 90
    • 0035203946 scopus 로고    scopus 로고
    • Induction of stress response renders human tumor cell lines resistant to curcumin-mediated apoptosis: Role of reactive oxygen intermediates
    • Khar A, Ali AM, Pardhasaradhi BV, Varalakshmi CH, Anjum R and Kumari AL: Induction of stress response renders human tumor cell lines resistant to curcumin-mediated apoptosis: role of reactive oxygen intermediates. Cell Stress Chaperones 6: 368-76, 2001.
    • (2001) Cell Stress Chaperones , vol.6 , pp. 368-376
    • Khar, A.1    Ali, A.M.2    Pardhasaradhi, B.V.3    Varalakshmi, C.H.4    Anjum, R.5    Kumari, A.L.6
  • 91
    • 0037070201 scopus 로고    scopus 로고
    • Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction
    • Choudhuri T, Pal S, Agwarwal ML, Das T and Sa G: Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction. FEBS Lett 512: 334-40, 2002.
    • (2002) FEBS Lett , vol.512 , pp. 334-340
    • Choudhuri, T.1    Pal, S.2    Agwarwal, M.L.3    Das, T.4    Sa, G.5
  • 92
    • 0036195104 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: Its suppression by ectopic expression of Bel-2 and Bcl-xl
    • Anto RJ, Mukhopadhyay A, Denning K and Aggarwal BB: Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bel-2 and Bcl-xl. Carcinogenesis 23: 143-50, 2002.
    • (2002) Carcinogenesis , vol.23 , pp. 143-150
    • Anto, R.J.1    Mukhopadhyay, A.2    Denning, K.3    Aggarwal, B.B.4
  • 93
  • 94
    • 0032523030 scopus 로고    scopus 로고
    • Nonselective inhibition of proliferation of transformed and nontransformed cells by the anticancer agent curcumin (diferuloylmethane)
    • Gautam SC, Xu YX, Pindolia KR, Janakiraman N and Chapman RA: Nonselective inhibition of proliferation of transformed and nontransformed cells by the anticancer agent curcumin (diferuloylmethane). Biochem Pharmacol 55: 1333-7, 1998.
    • (1998) Biochem Pharmacol , vol.55 , pp. 1333-1337
    • Gautam, S.C.1    Xu, Y.X.2    Pindolia, K.R.3    Janakiraman, N.4    Chapman, R.A.5
  • 95
    • 0033862619 scopus 로고    scopus 로고
    • Cytotoxicity, antioxidant and anti-inflammatory activities of curcumins I-III from Curcuma longa
    • Ramsewak RS, DeWitt DL and Nair MG: Cytotoxicity, antioxidant and anti-inflammatory activities of curcumins I-III from Curcuma longa. Phytomedicine 7: 303-8, 2000.
    • (2000) Phytomedicine , vol.7 , pp. 303-308
    • Ramsewak, R.S.1    DeWitt, D.L.2    Nair, M.G.3
  • 96
    • 0030271587 scopus 로고    scopus 로고
    • Curcumin inhibits the proliferation and cell cycle progression of human umbilical vein endothelial cell
    • Singh AK, Sidhu GS, Deepa T and Maheshwari RK: Curcumin inhibits the proliferation and cell cycle progression of human umbilical vein endothelial cell. Cancer Lett 107: 109-15, 1996.
    • (1996) Cancer Lett , vol.107 , pp. 109-115
    • Singh, A.K.1    Sidhu, G.S.2    Deepa, T.3    Maheshwari, R.K.4
  • 98
    • 18844481997 scopus 로고    scopus 로고
    • Curcumin inhibits cell cycle progression of immortalized human umbilical vein endothelial (ECV304) cells by up-regulating cyclin-dependent kinase inhibitor, p21 WAF1/CIP 1, p27KIP1 and p53
    • Park MJ, Kim EH, Park IC, Lee HC, Woo SH, Lee JY, Hong YJ, Rhee CH, Choi SH, Shim BS, Lee SH and Hong SI: Curcumin inhibits cell cycle progression of immortalized human umbilical vein endothelial (ECV304) cells by up-regulating cyclin-dependent kinase inhibitor, p21 WAF1/CIP1, p27KIP1 and p53. Int J Oncol 21: 379-83, 2002.
    • (2002) Int J Oncol , vol.21 , pp. 379-383
    • Park, M.J.1    Kim, E.H.2    Park, I.C.3    Lee, H.C.4    Woo, S.H.5    Lee, J.Y.6    Hong, Y.J.7    Rhee, C.H.8    Choi, S.H.9    Shim, B.S.10    Lee, S.H.11    Hong, S.I.12
  • 99
    • 0031927214 scopus 로고    scopus 로고
    • Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells
    • Khafif A, Schantz SP, Chou TC, Edelstein D and Sacks PG: Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells. Carcinogenesis 19: 419-24, 1998.
    • (1998) Carcinogenesis , vol.19 , pp. 419-424
    • Khafif, A.1    Schantz, S.P.2    Chou, T.C.3    Edelstein, D.4    Sacks, P.G.5
  • 100
    • 0030882579 scopus 로고    scopus 로고
    • Inhibition of proliferation and apoptosis of human and rat T lymphocytes by curcumin, a curry pigment
    • Sikora E, Bielak-Zmijewska A, Piwocka K, Skierski J and Radziszewska E: Inhibition of proliferation and apoptosis of human and rat T lymphocytes by curcumin, a curry pigment. Biochem Pharmacol 54: 899-907, 1997.
    • (1997) Biochem Pharmacol , vol.54 , pp. 899-907
    • Sikora, E.1    Bielak-Zmijewska, A.2    Piwocka, K.3    Skierski, J.4    Radziszewska, E.5
  • 102
    • 0032555342 scopus 로고    scopus 로고
    • Apoptosis-like, reversible changes in plasma membrane asymmetry and permeability, and transient modifications in mitochondrial membrane potential induced by curcumin in rat thymocytes
    • Jaruga E, Salvioli S, Dobrucki J, Chrul S, Bandorowicz-Pikula J, Sikora E, Franceschi C, Cossarizza A and Bartosz G: Apoptosis-like, reversible changes in plasma membrane asymmetry and permeability, and transient modifications in mitochondrial membrane potential induced by curcumin in rat thymocytes. FEBS Lett 433: 287-93, 1998.
    • (1998) FEBS Lett , vol.433 , pp. 287-293
    • Jaruga, E.1    Salvioli, S.2    Dobrucki, J.3    Chrul, S.4    Bandorowicz-Pikula, J.5    Sikora, E.6    Franceschi, C.7    Cossarizza, A.8    Bartosz, G.9
  • 103
    • 0032534459 scopus 로고    scopus 로고
    • Apoptosis-independent alterations in membrane dynamics induced by curcumin
    • Jaruga E, Sokal A, Chrul S and Bartosz G: Apoptosis-independent alterations in membrane dynamics induced by curcumin. Exp Cell Res 245: 303-12, 1998.
    • (1998) Exp Cell Res , vol.245 , pp. 303-312
    • Jaruga, E.1    Sokal, A.2    Chrul, S.3    Bartosz, G.4
  • 104
    • 0034096640 scopus 로고    scopus 로고
    • Stimulatory effect of curcumin on osteoclast apoptosis
    • Ozaki K, Kawata Y, Amano S and Hanazawa S: Stimulatory effect of curcumin on osteoclast apoptosis. Biochem Pharmacol 59: 1577-81, 2000.
    • (2000) Biochem Pharmacol , vol.59 , pp. 1577-1581
    • Ozaki, K.1    Kawata, Y.2    Amano, S.3    Hanazawa, S.4
  • 105
    • 0036158769 scopus 로고    scopus 로고
    • Sensitive markers used to identify compounds that trigger apoptosis in cultured hepatocytes
    • Gomez-Lechon MJ, O'Connor E, Castell JV and Jover R: Sensitive markers used to identify compounds that trigger apoptosis in cultured hepatocytes. Toxicol Sci 65: 299-308, 2002.
    • (2002) Toxicol Sci , vol.65 , pp. 299-308
    • Gomez-Lechon, M.J.1    O'Connor, E.2    Castell, J.V.3    Jover, R.4
  • 106
    • 0028867742 scopus 로고
    • Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane)
    • Singh S and Aggarwal BB: Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J Biol Chem 270: 24995-5000, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 24995-25000
    • Singh, S.1    Aggarwal, B.B.2
  • 107
    • 0030926135 scopus 로고    scopus 로고
    • Curcumin, a compound with anti-inflammatory and anti-oxidant properties, down-regulates chemokine expression in bone marrow stromal cells
    • Xu YX, Pindolia KR, Janakiraman N, Noth CJ, Chapman RA and Gautam SC: Curcumin, a compound with anti-inflammatory and anti-oxidant properties, down-regulates chemokine expression in bone marrow stromal cells. Exp Hematol 2-5: 413-22, 1997.
    • (1997) Exp Hematol , vol.2-5 , pp. 413-422
    • Xu, Y.X.1    Pindolia, K.R.2    Janakiraman, N.3    Noth, C.J.4    Chapman, R.A.5    Gautam, S.C.6
  • 108
    • 0034490854 scopus 로고    scopus 로고
    • Inhibitory effects of curcumin and capsaicin on phorbol ester-induced activation of eukaryotic transcription factors, NF-κB and AP-1
    • Surh YJ, Han SS, Keum YS, Seo HJ and Lee SS: Inhibitory effects of curcumin and capsaicin on phorbol ester-induced activation of eukaryotic transcription factors, NF-κB and AP-1. Biofactors 12: 107-12, 2000.
    • (2000) Biofactors , vol.12 , pp. 107-112
    • Surh, Y.J.1    Han, S.S.2    Keum, Y.S.3    Seo, H.J.4    Lee, S.S.5
  • 109
    • 0035997978 scopus 로고    scopus 로고
    • Curcumin suppresses activation of NF-κB, and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells
    • Han SS, Keum YS, Seo HJ and Surh YJ: Curcumin suppresses activation of NF-κB, and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells. J Biochem Mol Biol 35: 337-42, 2002.
    • (2002) J Biochem Mol Biol , vol.35 , pp. 337-342
    • Han, S.S.1    Keum, Y.S.2    Seo, H.J.3    Surh, Y.J.4
  • 110
    • 0036569563 scopus 로고    scopus 로고
    • Basal levels and patterns of anticancer drug-induced activation of nuclear factor-kappaB (NFkappaB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells
    • Chuang SE, Yeh PY, Lu YS, Lai GM, Liao CM, Gao M and Cheng AL: Basal levels and patterns of anticancer drug-induced activation of nuclear factor-kappaB (NFkappaB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells. Biochem Pharmacol 63: 1709-16, 2002.
    • (2002) Biochem Pharmacol , vol.63 , pp. 1709-1716
    • Chuang, S.E.1    Yeh, P.Y.2    Lu, Y.S.3    Lai, G.M.4    Liao, C.M.5    Gao, M.6    Cheng, A.L.7
  • 111
    • 0029047933 scopus 로고
    • Inhibition of tumor necrosis factor by curcumin, a phytochemical
    • Chan MM: Inhibition of tumor necrosis factor by curcumin, a phytochemical. Biochem Pharmacol 49: 1551-6, 1995.
    • (1995) Biochem Pharmacol , vol.49 , pp. 1551-1556
    • Chan, M.M.1
  • 112
    • 0034876804 scopus 로고    scopus 로고
    • A curcuminoid and sesquiterpenes as inhibitors of macrophage TNF-alpha release from Curcuma zedoaria
    • Jang MK, Sohn DH and Ryu JH: A curcuminoid and sesquiterpenes as inhibitors of macrophage TNF-alpha release from Curcuma zedoaria. Planta Med 67: 550-2, 2001.
    • (2001) Planta Med , vol.67 , pp. 550-552
    • Jang, M.K.1    Sohn, D.H.2    Ryu, J.H.3
  • 113
    • 0032991568 scopus 로고    scopus 로고
    • Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages
    • Abe Y, Hashimoto S and Horie T: Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages. Pharmacol Res 39: 41-7, 1999.
    • (1999) Pharmacol Res , vol.39 , pp. 41-47
    • Abe, Y.1    Hashimoto, S.2    Horie, T.3
  • 115
    • 0033568674 scopus 로고    scopus 로고
    • Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity
    • Jobin C, Bradham CA, Russo MP, Juma B, Narula AS, Brenner DA and Sartor RB: Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity. J Immunol 163: 3474-83, 1999.
    • (1999) J Immunol , vol.163 , pp. 3474-3483
    • Jobin, C.1    Bradham, C.A.2    Russo, M.P.3    Juma, B.4    Narula, A.S.5    Brenner, D.A.6    Sartor, R.B.7
  • 116
    • 0037105505 scopus 로고    scopus 로고
    • Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the cell surface:impact on human pancreatic carcinoma cell growth by autocrine regulation
    • Hidaka H, Ishiko T, Furuhashi T, Kamohara H, Suzuki S, Miyazaki M, Ikeda O, Mita S, Setoguchi T and Ogawa M: Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the cell surface:impact on human pancreatic carcinoma cell growth by autocrine regulation. Cancer 95: 1206-14, 2002.
    • (2002) Cancer , vol.95 , pp. 1206-1214
    • Hidaka, H.1    Ishiko, T.2    Furuhashi, T.3    Kamohara, H.4    Suzuki, S.5    Miyazaki, M.6    Ikeda, O.7    Mita, S.8    Setoguchi, T.9    Ogawa, M.10
  • 117
    • 0031813252 scopus 로고    scopus 로고
    • Curcumin inhibits SK-Hep-I hepatocellular carcinoma cell invasion in vitro and suppresses matrix metalloproteinase-9 secretion
    • Lin LI, Ke YF, Ko YC and Lin JK: Curcumin inhibits SK-Hep-I hepatocellular carcinoma cell invasion in vitro and suppresses matrix metalloproteinase-9 secretion. Oncology 55: 349-53, 1998.
    • (1998) Oncology , vol.55 , pp. 349-353
    • Lin, L.I.1    Ke, Y.F.2    Ko, Y.C.3    Lin, J.K.4
  • 118
    • 0034615942 scopus 로고    scopus 로고
    • Curcuminoids inhibit the angiogenic response stimulated by fibroblast growth factor-2, including expression of matrix metalloproteinase gelatinase B
    • Mohan R, Sivak J, Ashton P, Russo LA, Pham BQ, Kasahara N, Raizman MB and Fini ME: Curcuminoids inhibit the angiogenic response stimulated by fibroblast growth factor-2, including expression of matrix metalloproteinase gelatinase B. J Biol Chem 2 75: 10405-12, 2000.
    • (2000) J Biol Chem 2 , vol.75 , pp. 10405-10412
    • Mohan, R.1    Sivak, J.2    Ashton, P.3    Russo, L.A.4    Pham, B.Q.5    Kasahara, N.6    Raizman, M.B.7    Fini, M.E.8
  • 119
    • 0036252640 scopus 로고    scopus 로고
    • Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappaB) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes
    • Liacini A, Sylvester J, Li WQ and Zafarullah M: Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappaB) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes. Matrix Biol 21: 251-62, 2002.
    • (2002) Matrix Biol , vol.21 , pp. 251-262
    • Liacini, A.1    Sylvester, J.2    Li, W.Q.3    Zafarullah, M.4
  • 120
    • 0037040892 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor up-regulates matrix metalloproteinase-9 and -13 in rat osteoblasts. Relevance to intracellular signaling pathways
    • Onodera S, Nishihira J, Iwabuchi K, Koyama Y, Yoshida K, Tanaka S and Minami A: Macrophage migration inhibitory factor up-regulates matrix metalloproteinase-9 and -13 in rat osteoblasts. Relevance to intracellular signaling pathways. J Biol Chem 277: 7865-74, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 7865-7874
    • Onodera, S.1    Nishihira, J.2    Iwabuchi, K.3    Koyama, Y.4    Yoshida, K.5    Tanaka, S.6    Minami, A.7
  • 121
    • 0032520716 scopus 로고    scopus 로고
    • Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-κB activation
    • Kumar A, Dhawan S, Hardegen NJ and Aggarwal BB: curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-κB activation. Biochem Pharmacol 55: 775-83, 1998.
    • (1998) Biochem Pharmacol , vol.55 , pp. 775-783
    • Kumar, A.1    Dhawan, S.2    Hardegen, N.J.3    Aggarwal, B.B.4
  • 122
    • 0032821829 scopus 로고    scopus 로고
    • Curcuma longa inhibits TNF-alpha induced expression of adhesion molecules on human umbilical vein endothelial cells
    • Gupta B and Ghosh B: Curcuma longa inhibits TNF-alpha induced expression of adhesion molecules on human umbilical vein endothelial cells. Int J Immunopharmacol 21: 745-57, 1999.
    • (1999) Int J Immunopharmacol , vol.21 , pp. 745-757
    • Gupta, B.1    Ghosh, B.2
  • 123
    • 0030939425 scopus 로고    scopus 로고
    • The dietary pigment curcumin reduces endothelial tissue factor gene expression by inhibiting binding of AP-1 to the DNA and activation of NF-κB
    • Bierhaus A, Zhang Y, Quehenberger P, Luther T, Haase M, Muller M, Mackman N, Ziegler R and Nawroth PP: The dietary pigment curcumin reduces endothelial tissue factor gene expression by inhibiting binding of AP-1 to the DNA and activation of NF-κB. Thromb Haemost 77: 772-82, 1997.
    • (1997) Thromb Haemost , vol.77 , pp. 772-782
    • Bierhaus, A.1    Zhang, Y.2    Quehenberger, P.3    Luther, T.4    Haase, M.5    Muller, M.6    Mackman, N.7    Ziegler, R.8    Nawroth, P.P.9
  • 124
    • 0032996089 scopus 로고    scopus 로고
    • Curcumin inhibits cyclooxygenase-2 transcription in bile acid- and phorbol ester-treated human gastrointestinal epithelial cells
    • Zhang F, Altorki NK, Mestre JR, Subbaramaiah K and Dannenberg AJ: Curcumin inhibits cyclooxygenase-2 transcription in bile acid- and phorbol ester-treated human gastrointestinal epithelial cells. Carcinogenesis 20: 445-51, 1999.
    • (1999) Carcinogenesis , vol.20 , pp. 445-451
    • Zhang, F.1    Altorki, N.K.2    Mestre, J.R.3    Subbaramaiah, K.4    Dannenberg, A.J.5
  • 125
    • 0033613436 scopus 로고    scopus 로고
    • Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex
    • Plummer SM, Holloway KA, Manson MM, Munks RJ, Kaptein A, Farrow S and Howells L: Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex. Oncogene 18: 6013-20, 1999.
    • (1999) Oncogene , vol.18 , pp. 6013-6020
    • Plummer, S.M.1    Holloway, K.A.2    Manson, M.M.3    Munks, R.J.4    Kaptein, A.5    Farrow, S.6    Howells, L.7
  • 126
    • 0035976049 scopus 로고    scopus 로고
    • Specific inhibition of cyclooxygenase-2 (COX2) expression by dietary curcumin in HT-29 human colon cancer cells
    • Goel A, Boland CR and Chauhan DP: Specific inhibition of cyclooxygenase-2 (COX2) expression by dietary curcumin in HT-29 human colon cancer cells. Cancer Lett 172: 111-8, 2001.
    • (2001) Cancer Lett , vol.172 , pp. 111-118
    • Goel, A.1    Boland, C.R.2    Chauhan, D.P.3
  • 127
    • 0035451363 scopus 로고    scopus 로고
    • Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: Down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation
    • Surh YJ, Chun KS, Cha HH, Han SS, Keum YS, Park KK and Lee SS: Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat Res 480-481: 243-68, 2001.
    • (2001) Mutat Res , vol.480-481 , pp. 243-268
    • Surh, Y.J.1    Chun, K.S.2    Cha, H.H.3    Han, S.S.4    Keum, Y.S.5    Park, K.K.6    Lee, S.S.7
  • 128
    • 0032525741 scopus 로고    scopus 로고
    • In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties
    • Chan MM, Huang HI, Fenton MR and Fong D: In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties. Biochem Pharmacol 55: 1955-62, 1998.
    • (1998) Biochem Pharmacol , vol.55 , pp. 1955-1962
    • Chan, M.M.1    Huang, H.I.2    Fenton, M.R.3    Fong, D.4
  • 129
    • 0028928877 scopus 로고
    • Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages
    • Brouet I and Ohshima H: Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun 206: 533-40, 1995.
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 533-540
    • Brouet, I.1    Ohshima, H.2
  • 130
    • 0029128319 scopus 로고
    • Effects of three dietary phytochemicals from tea, rosemary and turmeric on inflammation-induced nitrite production
    • Chan MM, Ho CT and Huang HI: Effects of three dietary phytochemicals from tea, rosemary and turmeric on inflammation-induced nitrite production. Cancer Lett 96: 23-9, 1995.
    • (1995) Cancer Lett , vol.96 , pp. 23-29
    • Chan, M.M.1    Ho, C.T.2    Huang, H.I.3
  • 131
    • 0034578521 scopus 로고    scopus 로고
    • Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through downregulation of IkappaB kinase and NFkappaB activation in macrophages
    • Pan MH, Lin-Shiau SY and Lin JK: Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through downregulation of IkappaB kinase and NFkappaB activation in macrophages. Biochem Pharmacol 60: 1665-76, 2000.
    • (2000) Biochem Pharmacol , vol.60 , pp. 1665-1676
    • Pan, M.H.1    Lin-Shiau, S.Y.2    Lin, J.K.3
  • 132
    • 0033785918 scopus 로고    scopus 로고
    • Effect of curcumin on the production of nitric oxide by cultured rat mammary gland
    • Onoda M and Inano H: Effect of curcumin on the production of nitric oxide by cultured rat mammary gland. Nitric Oxide 4: 505-15, 2000.
    • (2000) Nitric Oxide , vol.4 , pp. 505-515
    • Onoda, M.1    Inano, H.2
  • 133
    • 0037093926 scopus 로고    scopus 로고
    • Curcumin enhances cytotoxicity of chemotherapeutic agents in prostate cancer cells by inducing p21 (WAF1/CIP1) and C/EBPbeta expressions and suppressing NF-kappaB activation
    • Hour TC, Chen J, Huang CY, Guan JY, Lu SH and Pu YS: Curcumin enhances cytotoxicity of chemotherapeutic agents in prostate cancer cells by inducing p21 (WAF1/CIP1) and C/EBPbeta expressions and suppressing NF-kappaB activation. Prostate 51: 211-8, 2002.
    • (2002) Prostate , vol.51 , pp. 211-218
    • Hour, T.C.1    Chen, J.2    Huang, C.Y.3    Guan, J.Y.4    Lu, S.H.5    Pu, Y.S.6
  • 134
    • 0026045073 scopus 로고
    • Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells
    • Huang TS, Lee SC and Lin JK: Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells. Proc Natl Acad Sci USA 88: 52926, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 52926
    • Huang, T.S.1    Lee, S.C.2    Lin, J.K.3
  • 135
    • 0027157651 scopus 로고
    • Tumor necrosis factor-alpha induces expression of monocyte chemoattractant JE via fos and jun genes in clonal osteoblastic MC3T3-E1 cells
    • Hanazawa S, Takeshita A, Amano S, Semba T, Nirazuka T, Katoh H and Kitano S: Tumor necrosis factor-alpha induces expression of monocyte chemoattractant JE via fos and jun genes in clonal osteoblastic MC3T3-E1 cells. J Biol Chem 268: 9526-32, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 9526-9532
    • Hanazawa, S.1    Takeshita, A.2    Amano, S.3    Semba, T.4    Nirazuka, T.5    Katoh, H.6    Kitano, S.7
  • 136
    • 0028043644 scopus 로고
    • Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger RNAs in mouse skin
    • Kakar SS and Roy D: Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger RNAs in mouse skin. Cancer Lett 87: 85-9, 1994.
    • (1994) Cancer Lett , vol.87 , pp. 85-89
    • Kakar, S.S.1    Roy, D.2
  • 137
    • 0027999652 scopus 로고
    • Effect of curcumin on 12-O-tetradecanoyl-phorbol-13-acetate- and ultraviolet B light-induced expression of c-Jun and c-Fos in J136 cells and in mouse epidermis
    • Lu YP, Chang RL, Lou YR, Huang MT, Newmark HL, Reuhl KR and Conney AH: Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate- and ultraviolet B light-induced expression of c-Jun and c-Fos in J136 cells and in mouse epidermis. Carcinogenesis 15: 2363-70, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 2363-2370
    • Lu, Y.P.1    Chang, R.L.2    Lou, Y.R.3    Huang, M.T.4    Newmark, H.L.5    Reuhl, K.R.6    Conney, A.H.7
  • 138
    • 0031439994 scopus 로고    scopus 로고
    • Curcumin inhibits IL-1 alpha and TNF-alpha induction of AP-1 and NF-kB DNA-binding activity in bone marrow stromal cells
    • Xu YX, Pindolia KR, Janakiraman N, Chapman RA and Gautarn SC: Curcumin inhibits IL-1 alpha and TNF-alpha induction of AP-1 and NF-kB DNA-binding activity in bone marrow stromal cells. Hematopathol Mol Hematol 11: 49-62, 1997.
    • (1997) Hematopathol Mol Hematol , vol.11 , pp. 49-62
    • Xu, Y.X.1    Pindolia, K.R.2    Janakiraman, N.3    Chapman, R.A.4    Gautarn, S.C.5
  • 139
    • 0034211263 scopus 로고    scopus 로고
    • AP-1 mediated signal transduction in thrombin-induced regulation of PAL-1 expression in human mesangial cells
    • Chen X, He Q, Liu W, Xu Q, Ye Y, Fu B and Yu L: AP-1 mediated signal transduction in thrombin-induced regulation of PAL-1 expression in human mesangial cells. Chin Med J (Engl) 113: 514-9, 2000.
    • (2000) Chin Med J (Engl) , vol.113 , pp. 514-519
    • Chen, X.1    He, Q.2    Liu, W.3    Xu, Q.4    Ye, Y.5    Fu, B.6    Yu, L.7
  • 140
    • 0033963647 scopus 로고    scopus 로고
    • Suppression of transcription factor Egr-1 by curcumin
    • Pendurthi UR and Rao LV: Suppression of transcription factor Egr-1 by curcumin. Thromb Res 97: 179-89, 2000.
    • (2000) Thromb Res , vol.97 , pp. 179-189
    • Pendurthi, U.R.1    Rao, L.V.2
  • 142
    • 0028556758 scopus 로고
    • Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells
    • Korutla L and Kumar R: Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells. Biochim Biophys Acta 1224: 597-600, 1994.
    • (1994) Biochim Biophys Acta , vol.1224 , pp. 597-600
    • Korutla, L.1    Kumar, R.2
  • 143
    • 0029081718 scopus 로고
    • Inhibition of ligand-induced activation of epidermal growth factor receptor tyrosine phosphorylation by curcumin
    • Korutla L, Cheung JY, Mendelsohn J and Kumar R: Inhibition of ligand-induced activation of epidermal growth factor receptor tyrosine phosphorylation by curcumin. Carcinogenesis 16: 1741-5, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 1741-1745
    • Korutla, L.1    Cheung, J.Y.2    Mendelsohn, J.3    Kumar, R.4
  • 144
    • 0032789660 scopus 로고    scopus 로고
    • Curcumin inhibits tyrosine kinase activity of p185neu and also depletes p185neu
    • Hong RL, Spohn WH and Hung MC: Curcumin inhibits tyrosine kinase activity of p185neu and also depletes p185neu. Clin Cancer Res 5: 1884-91, 1999.
    • (1999) Clin Cancer Res , vol.5 , pp. 1884-1891
    • Hong, R.L.1    Spohn, W.H.2    Hung, M.C.3
  • 145
    • 0034090594 scopus 로고    scopus 로고
    • Therapeutic potential of curcumin in human prostate cancer. II. Curcumin inhibits tyrosine kinase activity of epidermal growth factor receptor and depletes the protein
    • Dorai T, Gehani N and Katz A: Therapeutic potential of curcumin in human prostate cancer. II. curcumin inhibits tyrosine kinase activity of epidermal growth factor receptor and depletes the protein. Mol Urol 4: 1-6, 2000.
    • (2000) Mol Urol , vol.4 , pp. 1-6
    • Dorai, T.1    Gehani, N.2    Katz, A.3
  • 146
    • 0027173480 scopus 로고
    • Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol-13-acetate in NIH 3T3 cells
    • Liu JY, Lin SJ and Lin JK: Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol13-acetate in NIH 3T3 cells. Carcinogenesis 14: 857-61, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 857-861
    • Liu, J.Y.1    Lin, S.J.2    Lin, J.K.3
  • 147
    • 0028220931 scopus 로고
    • Curcumin is a non-competitive and selective inhibitor of phosphorylase kinase
    • Reddy S and Aggarwal BB: Curcumin is a non-competitive and selective inhibitor of phosphorylase kinase. FEBS Lett 341: 19-22, 1994.
    • (1994) FEBS Lett , vol.341 , pp. 19-22
    • Reddy, S.1    Aggarwal, B.B.2
  • 148
    • 0030158145 scopus 로고    scopus 로고
    • Inhibition of cyclic AMP-dependent protein kinase by curcumin
    • Hasmeda M and Polya GM: Inhibition of cyclic AMP-dependent protein kinase by curcumin. Phytochemistry 42: 599-605, 1996.
    • (1996) Phytochemistry , vol.42 , pp. 599-605
    • Hasmeda, M.1    Polya, G.M.2
  • 149
    • 0026029402 scopus 로고
    • Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis
    • Huang MT, Lysz T, Ferraro T, Abidi TF, Laskin JD and Conney AH: Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res 51: 813-9, 1991.
    • (1991) Cancer Res , vol.51 , pp. 813-819
    • Huang, M.T.1    Lysz, T.2    Ferraro, T.3    Abidi, T.F.4    Laskin, J.D.5    Conney, A.H.6
  • 150
    • 0034321972 scopus 로고    scopus 로고
    • Curcumin inhibits lipoxygenase by binding to its central cavity: Theoretical and x-ray evidence
    • Skrzypczak-Jankun E, McCabe NP, Selman SH and Jankun J: curcumin inhibits lipoxygenase by binding to its central cavity: theoretical and X-ray evidence. Int J Mol Med 6: 521-6, 2000.
    • (2000) Int J Mol Med , vol.6 , pp. 521-526
    • Skrzypczak-Jankun, E.1    McCabe, N.P.2    Selman, S.H.3    Jankun, J.4
  • 151
    • 0026628343 scopus 로고
    • Induction of glutathione S-transferase activity by curcumin in mice
    • Susan M and Rao MN: Induction of glutathione S-transferase activity by curcumin in mice. Arzneimittelforschung 42: 962-4, 1992.
    • (1992) Arzneimittelforschung , vol.42 , pp. 962-964
    • Susan, M.1    Rao, M.N.2
  • 152
    • 0030032384 scopus 로고    scopus 로고
    • Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver
    • Oetari S, Sudibyo M, Commandeur JN, Samhoedi R and Vermeulen NP: Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver. Biochem Pharmacol 51: 39-45, 1996.
    • (1996) Biochem Pharmacol , vol.51 , pp. 39-45
    • Oetari, S.1    Sudibyo, M.2    Commandeur, J.N.3    Samhoedi, R.4    Vermeulen, N.P.5
  • 154
    • 0027930688 scopus 로고
    • Inhibitory effect of curcumin on xanthine dehydrogenase/oxidase induced by phorbol-12-myristate-13-acetate in NIH3 T3 cells
    • Lin JK and Shih CA: Inhibitory effect of curcumin on xanthine dehydrogenase/oxidase induced by phorbol-12-myristate-13-acetate in NIH3 T3 cells. Carcinogenesis 15: 1717-21, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 1717-1721
    • Lin, J.K.1    Shih, C.A.2
  • 155
    • 0028131897 scopus 로고
    • Effect of retinol deficiency and curcumin or turmeric feeding on brain Na(+)-K+ adenosine triphosphatase activity
    • Kaul S and Krishnakanth TP: Effect of retinol deficiency and curcumin or turmeric feeding on brain Na(+)-K+ adenosine triphosphatase activity. Mol Cell Biochem 137: 101-7, 1994.
    • (1994) Mol Cell Biochem , vol.137 , pp. 101-107
    • Kaul, S.1    Krishnakanth, T.P.2
  • 156
    • 0035018226 scopus 로고    scopus 로고
    • Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo
    • Thaphyal R and Maru GB: Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo. Food Chem Toxicol 39: 541-7, 2001.
    • (2001) Food Chem Toxicol , vol.39 , pp. 541-547
    • Thaphyal, R.1    Maru, G.B.2
  • 157
    • 0031725843 scopus 로고    scopus 로고
    • Effect of curcumin on the aryl hydrocarbon receptor and cytochrome P450 1A1 in MCF-7 human breast carcinoma cells
    • Ciolino HP, Daschner PJ, Wang TT and Yeh GC: Effect of curcumin on the aryl hydrocarbon receptor and cytochrome P450 1A1 in MCF-7 human breast carcinoma cells. Biochem Pharmacol 56: 197-206, 1998.
    • (1998) Biochem Pharmacol , vol.56 , pp. 197-206
    • Ciolino, H.P.1    Daschner, P.J.2    Wang, T.T.3    Yeh, G.C.4
  • 159
    • 0037176872 scopus 로고    scopus 로고
    • Evidence for a global inhibitor-induced conformation change on the Ca(2+)-ATPase of sarcoplasmic reticulum, from paired inhibitor studies
    • Logan-Smith MJ, East JM and Lee AG: Evidence for a global inhibitor-induced conformation change on the Ca(2+)-ATPase of sarcoplasmic reticulum, from paired inhibitor studies. Biochemistry 41: 2869-75, 2002.
    • (2002) Biochemistry , vol.41 , pp. 2869-2875
    • Logan-Smith, M.J.1    East, J.M.2    Lee, A.G.3
  • 160
    • 0034747369 scopus 로고    scopus 로고
    • Inhibition of the SERCA Ca2+ pumps by curcumin. Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP
    • Bilmen JG, Khan SZ, Javed MH and Michelangeli F: Inhibition of the SERCA Ca2+ pumps by curcumin. Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP. Eur J Biochem 268: 6318-27, 2001.
    • (2001) Eur J Biochem , vol.268 , pp. 6318-6327
    • Bilmen, J.G.1    Khan, S.Z.2    Javed, M.H.3    Michelangeli, F.4
  • 161
    • 0037133930 scopus 로고    scopus 로고
    • The slippage of the Ca2+ pump and its control by anions and curcumin in skeletal and cardiac sarcoplasmic reticulum
    • Sumbilla C, Lewis D, Hammerschmidt T and Inesi G: The slippage of the Ca2+ pump and its control by anions and curcumin in skeletal and cardiac sarcoplasmic reticulum. J Biol Chem 277: 13900-6, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 13900-13906
    • Sumbilla, C.1    Lewis, D.2    Hammerschmidt, T.3    Inesi, G.4
  • 162
    • 0030856114 scopus 로고    scopus 로고
    • Inhibitory effect on curcumin on mammalian phospholipase D activity
    • Yamamoto H, Hanada K, Kawasaki K and Nishijima M: Inhibitory effect on curcumin on mammalian phospholipase D activity. FEBS Lett 417: 196-8, 1997.
    • (1997) FEBS Lett , vol.417 , pp. 196-198
    • Yamamoto, H.1    Hanada, K.2    Kawasaki, K.3    Nishijima, M.4
  • 163
    • 0032883350 scopus 로고    scopus 로고
    • Curcumin inhibits Th1 cytokine profile in CD4+ T cells by suppressing interleukin-12 production in macrophages
    • Kang BY, Song YJ, Kim KM, Choe YK, Hwang SY and Kim TS: Curcumin inhibits Th1 cytokine profile in CD4+ T cells by suppressing interleukin-12 production in macrophages. Br J Pharmacol 128: 380-4, 1999.
    • (1999) Br J Pharmacol , vol.128 , pp. 380-384
    • Kang, B.Y.1    Song, Y.J.2    Kim, K.M.3    Choe, Y.K.4    Hwang, S.Y.5    Kim, T.S.6
  • 164
    • 0033429405 scopus 로고    scopus 로고
    • Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophages by curcumin
    • Kang BY, Chung SW, Chung W, Im S, Hwang SY and Kim TS: Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophages by curcumin. Eur J Pharmacol 384: 191-5, 1999.
    • (1999) Eur J Pharmacol , vol.384 , pp. 191-195
    • Kang, B.Y.1    Chung, S.W.2    Chung, W.3    Im, S.4    Hwang, S.Y.5    Kim, T.S.6
  • 165
    • 0033848437 scopus 로고    scopus 로고
    • Genistein and curcumin block TGF-beta 1-induced u-PA expression and migratory and invasive phenotype in mouse epidermal keratinocytes
    • Santibanez JF, Quintanilla M and Martinez J: Genistein and curcumin block TGF-beta 1-induced u-PA expression and migratory and invasive phenotype in mouse epidermal keratinocytes. Nutr Cancer 37: 49-54, 2000.
    • (2000) Nutr Cancer , vol.37 , pp. 49-54
    • Santibanez, J.F.1    Quintanilla, M.2    Martinez, J.3
  • 166
    • 0036317559 scopus 로고    scopus 로고
    • Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype
    • Fenton JI, Wolff MS, Orth MW and Hord NG: Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype. Carcinogenesis 23: 1065-70, 2002.
    • (2002) Carcinogenesis , vol.23 , pp. 1065-1070
    • Fenton, J.I.1    Wolff, M.S.2    Orth, M.W.3    Hord, N.G.4
  • 167
    • 0034655773 scopus 로고    scopus 로고
    • Curcumin, an antioxidant and antiinflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress
    • Motterlini R, Foresti R, Bassi R and Green CJ: Curcumin, an antioxidant and antiinflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. Free Radic Biol Med 28: 1303-12, 2000.
    • (2000) Free Radic Biol Med , vol.28 , pp. 1303-1312
    • Motterlini, R.1    Foresti, R.2    Bassi, R.3    Green, C.J.4
  • 169
    • 0032523916 scopus 로고    scopus 로고
    • Effects of curcumin on P-glycoprotein in primary cultures of rat hepatocytes
    • Romiti N, Tongiani R, Cervelli F and Chieli E: Effects of curcumin on P-glycoprotein in primary cultures of rat hepatocytes. Life Sci 62: 2349-58, 1998.
    • (1998) Life Sci , vol.62 , pp. 2349-2358
    • Romiti, N.1    Tongiani, R.2    Cervelli, F.3    Chieli, E.4
  • 170
    • 0037134763 scopus 로고    scopus 로고
    • Putative identification of functional interactions between DNA intercalating agents and topoisomerase II using the V79 in vitro micronucleus assay
    • Snyder RD and Arnone MR: Putative identification of functional interactions between DNA intercalating agents and topoisomerase II using the V79 in vitro micronucleus assay. Mutat Res 503: 21-35, 2002.
    • (2002) Mutat Res , vol.503 , pp. 21-35
    • Snyder, R.D.1    Arnone, M.R.2
  • 171
    • 0031696096 scopus 로고    scopus 로고
    • Stimulation of the stress-induced expression of stress proteins by curcumin in cultured cells and in rat tissues in vivo
    • Kato K, Ito H, Kamei K and Iwamoto I: Stimulation of the stress-induced expression of stress proteins by curcumin in cultured cells and in rat tissues in vivo. Cell Stress Chaperones 3: 152-60, 1998.
    • (1998) Cell Stress Chaperones , vol.3 , pp. 152-160
    • Kato, K.1    Ito, H.2    Kamei, K.3    Iwamoto, I.4
  • 172
    • 0030809345 scopus 로고    scopus 로고
    • Inhibition of farnesyl protein transferase by monoterpene, curcumin derivatives and gallotannin
    • Chen X, Hasuma T, Yano Y, Yoshimata T, Morishima Y, Wang Y and Otani S: Inhibition of farnesyl protein transferase by monoterpene, curcumin derivatives and gallotannin. Anticancer Res 17: 2555-64, 1997.
    • (1997) Anticancer Res , vol.17 , pp. 2555-2564
    • Chen, X.1    Hasuma, T.2    Yano, Y.3    Yoshimata, T.4    Morishima, Y.5    Wang, Y.6    Otani, S.7
  • 173
  • 174
    • 0028174061 scopus 로고
    • Function and activation of NF-kappa B in the immune system
    • Baeuerle PA and Henkel T: Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 12: 141-79, 1994.
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 175
    • 0027232067 scopus 로고
    • NF-kappa B and Rel: Participants in a multiform transcriptional regulatory system
    • Grilli M, Chiu JJ and Lenardo MJ: NF-kappa B and Rel: participants in a multiform transcriptional regulatory system. Int Rev Cytol 143: 1-62, 1993.
    • (1993) Int Rev Cytol , vol.143 , pp. 1-62
    • Grilli, M.1    Chiu, J.J.2    Lenardo, M.J.3
  • 176
    • 0025865317 scopus 로고
    • The inducible transcription activator NF-kappa B: Regulation by distinct protein subunits
    • Baeuerle PA: The inducible transcription activator NF-kappa B: regulation by distinct protein subunits. Biochim Biophys Acta 1072: 63-80, 1991.
    • (1991) Biochim Biophys Acta , vol.1072 , pp. 63-80
    • Baeuerle, P.A.1
  • 177
    • 0032055394 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappaB by direct modification in whole cells-mechanism of action of nordihydroguaiaritic acid, curcumin and thiol modifiers
    • Brennan P and O'Neill LA: Inhibition of nuclear factor kappaB by direct modification in whole cells - mechanism of action of nordihydroguaiaritic acid, curcumin and thiol modifiers. Biochem Pharmacol 55: 965-73, 1998.
    • (1998) Biochem Pharmacol , vol.55 , pp. 965-973
    • Brennan, P.1    O'Neill, L.A.2
  • 178
    • 0033786813 scopus 로고    scopus 로고
    • Verotoxin-1 induces tissue factor expression in human umbilical vein endothelial cells through activation of NFkappaB/Rel and AP-1
    • Ishii H, Takada K, Higuchi T and Sugiyama J: Verotoxin-1 induces tissue factor expression in human umbilical vein endothelial cells through activation of NFkappaB/Rel and AP-1. Thromb Haemost 84: 712-21, 2000.
    • (2000) Thromb Haemost , vol.84 , pp. 712-721
    • Ishii, H.1    Takada, K.2    Higuchi, T.3    Sugiyama, J.4
  • 179
    • 0034717046 scopus 로고    scopus 로고
    • L-929 cells harboring ectopically expressed ReIA resist curcumin-induced apoptosis
    • Anto RJ, Maliekal TT and Karunagaran D: L-929 cells harboring ectopically expressed ReIA resist curcumin-induced apoptosis. J Biol Chem 275: 15601-4, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 15601-15604
    • Anto, R.J.1    Maliekal, T.T.2    Karunagaran, D.3
  • 180
    • 85117739153 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) downregulates the constitutive activation of nuclear factor-kappaB and I kappa B alpha kinase in human multiple myeloma cells leading to suppression of proliferation and induction of apoptosis
    • in press
    • Bharti AC, Donato N, Singh S and Aggarwal BB: Curcumin (diferuloylmethane) downregulates the constitutive activation of nuclear factor-kappaB and I kappa B alpha kinase in human multiple myeloma cells leading to suppression of proliferation and induction of apoptosis. Blood (in press).
    • Blood
    • Bharti, A.C.1    Donato, N.2    Singh, S.3    Aggarwal, B.B.4
  • 181
    • 0034668151 scopus 로고    scopus 로고
    • Apoptosis and transcription factor NF-kB: A tale of association and dissociation
    • Aggarwal BB: Apoptosis and transcription factor NF-kB: a tale of association and dissociation. Biochem Pharmacol 60: 1033-1039, 2000.
    • (2000) Biochem Pharmacol , vol.60 , pp. 1033-1039
    • Aggarwal, B.B.1
  • 182
    • 0037203538 scopus 로고    scopus 로고
    • Nuclear factor-kappa B activation: A question of life and death
    • Shishodia S and Aggrwal BB: Nuclear factor-kappa B activation: a question of life and death. J Biochem Mol Biol 35: 28-40, 2002.
    • (2002) J Biochem Mol Biol , vol.35 , pp. 28-40
    • Shishodia, S.1    Aggrwal, B.B.2
  • 183
    • 0344641448 scopus 로고    scopus 로고
    • Transcription factors as targets for the drug development
    • Keri G, Toth I, eds. New York: Harwood Academic Publisher
    • Karunagaran D and Aggarwal BB: Transcription factors as targets for the drug development. In: Keri G, Toth I, eds. Molecular Pathomechanisms and New Trends in Drug Development. New York: Harwood Academic Publisher, 2002: 76-91.
    • (2002) Molecular Pathomechanisms and New Trends in Drug Development , pp. 76-91
    • Karunagaran, D.1    Aggarwal, B.B.2
  • 184
    • 4243687105 scopus 로고    scopus 로고
    • The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: The J136 model is predictive
    • Dhar A, Young MR, Colburn NH: The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: the J136 model is predictive. Mol Cell Biochem 234235: 185-93, 2002.
    • (2002) Mol Cell Biochem , vol.234-235 , pp. 185-193
    • Dhar, A.1    Young, M.R.2    Colburn, N.H.3
  • 185
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian E and Karin M: AP-1 as a regulator of cell life and death. Nat Cell Biol 4: E 131-6, 2002.
    • (2002) Nat Cell Biol , vol.4
    • Shaulian, E.1    Karin, M.2
  • 186
    • 0034190272 scopus 로고    scopus 로고
    • Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis
    • Hsu TC, Young MR, Cmarik J and Colburn NH: Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis. Free Radic Biol Med 28: 1338-48, 2000.
    • (2000) Free Radic Biol Med , vol.28 , pp. 1338-1348
    • Hsu, T.C.1    Young, M.R.2    Cmarik, J.3    Colburn, N.H.4
  • 187
    • 0028905444 scopus 로고
    • Transformation reversion induced in J136 RT101 cells by AP-1 inhibitors
    • Dong Z, Lavrovsky V and Colburn NH: Transformation reversion induced in J136 RT101 cells by AP-1 inhibitors. Carcinogenesis 16: 749-56, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 749-756
    • Dong, Z.1    Lavrovsky, V.2    Colburn, N.H.3
  • 188
    • 0032746328 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase mediates apoptotic signaling induced by N-(4-hydroxyphenyl)retinamide
    • Chen YR, Zhou G and Tan TH: c-Jun N-terminal kinase mediates apoptotic signaling induced by N-(4-hydroxyphenyl)retinamide. Mol Pharmacol 56: 1271-9, 1999.
    • (1999) Mol Pharmacol , vol.56 , pp. 1271-1279
    • Chen, Y.R.1    Zhou, G.2    Tan, T.H.3
  • 189
    • 0037044187 scopus 로고    scopus 로고
    • New and known symmetrical curcumin derivatives inhibit the formation of Fos-Jun-DNA complex
    • Hahm ER, Cheon G, Lee J, Kim B, Park C and Yang CH: New and known symmetrical curcumin derivatives inhibit the formation of Fos-Jun-DNA complex. Cancer Lett 184: 89-96, 2002.
    • (2002) Cancer Lett , vol.184 , pp. 89-96
    • Hahm, E.R.1    Cheon, G.2    Lee, J.3    Kim, B.4    Park, C.5    Yang, C.H.6
  • 190
    • 28944445468 scopus 로고
    • Mechanism of antiinflammatory actions of curcumin and boswellic acids
    • Ammon HP, Safayhi H, Mack T and Sabieraj J: Mechanism of antiinflammatory actions of curcumin and boswellic acids. J Ethnopharmacol 38: 113-9, 1993.
    • (1993) J Ethnopharmacol , vol.38 , pp. 113-119
    • Ammon, H.P.1    Safayhi, H.2    Mack, T.3    Sabieraj, J.4
  • 191
  • 192
    • 0027154638 scopus 로고
    • Cyclin D1 is a nuclear protein required for cell cycle progression in G1
    • Baldin V, Lukas J, Marcote MJ, Pagano M and Draetta G: Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev 7: 812-21, 1993.
    • (1993) Genes Dev , vol.7 , pp. 812-821
    • Baldin, V.1    Lukas, J.2    Marcote, M.J.3    Pagano, M.4    Draetta, G.5
  • 193
    • 0028129951 scopus 로고
    • The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas
    • Bartkova J, Lukas J, Strauss M and Bartek J: The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas. Int J Cancer 58: 568-73, 1994.
    • (1994) Int J Cancer , vol.58 , pp. 568-573
    • Bartkova, J.1    Lukas, J.2    Strauss, M.3    Bartek, J.4
  • 195
    • 0028331092 scopus 로고
    • Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
    • Gillett C, Fantl V, Smith R, Fisher C, Bartek J, Dickson C, Barnes D and Peters G: Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res 54: 1812-7, 1994.
    • (1994) Cancer Res , vol.54 , pp. 1812-1817
    • Gillett, C.1    Fantl, V.2    Smith, R.3    Fisher, C.4    Bartek, J.5    Dickson, C.6    Barnes, D.7    Peters, G.8
  • 198
    • 0028894280 scopus 로고
    • Abnormal patterns of D-type cyclin expression and GI regulation in human head and neck cancer
    • Bartkova J, Lukas J, Muller H, Strauss M, Gusterson B and Bartek J: Abnormal patterns of D-type cyclin expression and GI regulation in human head and neck cancer. Cancer Res 55: 949-56, 1995.
    • (1995) Cancer Res , vol.55 , pp. 949-956
    • Bartkova, J.1    Lukas, J.2    Muller, H.3    Strauss, M.4    Gusterson, B.5    Bartek, J.6
  • 199
    • 0028891798 scopus 로고
    • Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1
    • Adelaide J, Monges G, Derderian C, Seitz JF and Birnbaum D: Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1. Br J Cancer 71: 64-8, 1995.
    • (1995) Br J Cancer , vol.71 , pp. 64-68
    • Adelaide, J.1    Monges, G.2    Derderian, C.3    Seitz, J.F.4    Birnbaum, D.5
  • 203
    • 0034084926 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 is associated with metastatic prostate cancer to bone
    • Drobnjak M, Osman I, Scher HI, Fazzari M and Cordon-Cardo C: Overexpression of cyclin D1 is associated with metastatic prostate cancer to bone. Clin Cancer Res 6: 1891-5, 2000.
    • (2000) Clin Cancer Res , vol.6 , pp. 1891-1895
    • Drobnjak, M.1    Osman, I.2    Scher, H.I.3    Fazzari, M.4    Cordon-Cardo, C.5
  • 204
    • 0034638925 scopus 로고    scopus 로고
    • Molecular mechanisms underlying ErbB2/HER2 action in breast cancer
    • Harari D and Yarden Y: Molecular mechanisms underlying ErbB2/HER2 action in breast cancer. Oncogene 19: 6102-14, 2000.
    • (2000) Oncogene , vol.19 , pp. 6102-6114
    • Harari, D.1    Yarden, Y.2
  • 207
    • 0028889751 scopus 로고
    • Mice lacking cyclin D1 are small and show defects in eye and mammary gland development
    • Fantl V, Stamp G, Andrews A, Rosewell I and Dickson C: Mice lacking cyclin D1 are small and show defects in eye and mammary gland development. Genes Dev 9: 2364-72, 1995.
    • (1995) Genes Dev , vol.9 , pp. 2364-2372
    • Fantl, V.1    Stamp, G.2    Andrews, A.3    Rosewell, I.4    Dickson, C.5
  • 208
    • 0031240307 scopus 로고    scopus 로고
    • A specific role for cyclin D1 in mammary gland development
    • Sicinski P and Weinberg RA: A specific role for cyclin D1 in mammary gland development. J Mammary Gland Biol Neoplasia 2: 335-42, 1997.
    • (1997) J Mammary Gland Biol Neoplasia , vol.2 , pp. 335-342
    • Sicinski, P.1    Weinberg, R.A.2
  • 209
    • 0034471579 scopus 로고    scopus 로고
    • Fibroblast growth factor signalling and cyclin D1 function are necessary for normal mammary gland development during pregnancy. A transgenic mouse approach
    • Fantl V, Creer A, Dillon C, Bresnick J, Jackson D, Edwards P, Rosewell I and Dickson C: Fibroblast growth factor signalling and cyclin D1 function are necessary for normal mammary gland development during pregnancy. A transgenic mouse approach. Adv Exp Med Biol 480: 1-7, 2000.
    • (2000) Adv Exp Med Biol , vol.480 , pp. 1-7
    • Fantl, V.1    Creer, A.2    Dillon, C.3    Bresnick, J.4    Jackson, D.5    Edwards, P.6    Rosewell, I.7    Dickson, C.8
  • 210
    • 0035963435 scopus 로고    scopus 로고
    • Specific protection against breast cancers by cyclin D1 ablation
    • Yu Q, Geng Y and Sicinski P: Specific protection against breast cancers by cyclin D1 ablation. Nature 411: 1017-21, 2001.
    • (2001) Nature , vol.411 , pp. 1017-1021
    • Yu, Q.1    Geng, Y.2    Sicinski, P.3
  • 211
    • 0028970609 scopus 로고
    • Transforming p21 ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions
    • Albanese C, Johnson J, Watanabe G, Eklund N, Vu D, Arnold A and Pestell RG: Transforming p21 ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions. J Biol Chem 270: 23589-97, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 23589-23597
    • Albanese, C.1    Johnson, J.2    Watanabe, G.3    Eklund, N.4    Vu, D.5    Arnold, A.6    Pestell, R.G.7
  • 214
  • 215
    • 0037069939 scopus 로고    scopus 로고
    • Curcumin-induced suppression of cell proliferation correlates with donregulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation
    • in press
    • Mukhopadhyay A, Banerjee S, Stafford LJ, Xia C, X., Liu M and Aggarwal BB: Curcumin-induced suppression of cell proliferation correlates with donregulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation. Oncogene (in press).
    • Oncogene
    • Mukhopadhyay, A.1    Banerjee, S.2    Stafford, L.J.3    Xia, C.X.4    Liu, M.5    Aggarwal, B.B.6
  • 216
    • 0029928366 scopus 로고    scopus 로고
    • Tumor necrosis factor: Developments during the last dacade
    • Aggarwal BB and Natarajan K: Tumor necrosis factor: developments during the last dacade. Eur Cytokine Netw 7: 93-124, 1996.
    • (1996) Eur Cytokine Netw , vol.7 , pp. 93-124
    • Aggarwal, B.B.1    Natarajan, K.2
  • 217
    • 0025304016 scopus 로고
    • Cytokines and endothelial cell biology
    • Pober JS and Cotran RS: Cytokines and endothelial cell biology. Physiol Rev 70: 427-51, 1990.
    • (1990) Physiol Rev , vol.70 , pp. 427-451
    • Pober, J.S.1    Cotran, R.S.2
  • 218
    • 0027484675 scopus 로고
    • TNF in vascular pathology: The importance of plateletendothelium interactions
    • Grau GE and Lou J: TNF in vascular pathology: the importance of plateletendothelium interactions. Res Immunol 144: 355-63, 1993.
    • (1993) Res Immunol , vol.144 , pp. 355-363
    • Grau, G.E.1    Lou, J.2
  • 219
    • 0029101772 scopus 로고
    • Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers
    • Collins T, Read MA, Neish AS, Whitley MZ, Thanos D and Maniatis T: Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. Faseb J 9: 899-909, 1995.
    • (1995) Faseb J , vol.9 , pp. 899-909
    • Collins, T.1    Read, M.A.2    Neish, A.S.3    Whitley, M.Z.4    Thanos, D.5    Maniatis, T.6
  • 221
    • 0035980916 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase is involved in motility of endothelial cell
    • Shin EY, Kim SY and Kim EG: c-Jun N-terminal kinase is involved in motility of endothelial cell. Exp Mol Med 33: 276-83, 2001.
    • (2001) Exp Mol Med , vol.33 , pp. 276-283
    • Shin, E.Y.1    Kim, S.Y.2    Kim, E.G.3
  • 223
    • 0037103569 scopus 로고    scopus 로고
    • Modulation of P-glycoprotein expression and function by curcumin in multidrugresistant human KB cells
    • Anuchapreeda S, Leechanachai P, Smith MM, Ambudkar SV and Limtrakul PN: Modulation of P-glycoprotein expression and function by curcumin in multidrugresistant human KB cells. Biochem Pharmacol 64: 573-82, 2002.
    • (2002) Biochem Pharmacol , vol.64 , pp. 573-582
    • Anuchapreeda, S.1    Leechanachai, P.2    Smith, M.M.3    Ambudkar, S.V.4    Limtrakul, P.N.5
  • 224
    • 0030597060 scopus 로고    scopus 로고
    • Inhibition of glutathione S-transferase activity in human melanoma cells by alpha, beta-unsaturated carbonyl derivatives. Effects of acrolein, cinnamaldehyde, citral, crotonaldehyde, curcumin, ethacrynic acid, and trans-2-hexenal
    • Iersel ML, Ploemen JP, Struik I, van Amersfoort C, Keyzer AE, Schefferlie JG and van Bladeren PJ: Inhibition of glutathione S-transferase activity in human melanoma cells by alpha, betaunsaturated carbonyl derivatives. Effects of acrolein, cinnamaldehyde, citral, crotonaldehyde, curcumin, ethacrynic acid, and trans-2-hexenal. Chem Biol Interact 102: 117-32, 1996.
    • (1996) Chem Biol Interact , vol.102 , pp. 117-132
    • Iersel, M.L.1    Ploemen, J.P.2    Struik, I.3    Van Amersfoort, C.4    Keyzer, A.E.5    Schefferlie, J.G.6    Van Bladeren, P.J.7
  • 225
    • 0020422351 scopus 로고
    • Anti-inflammatory activity of curcumin analogues
    • Rao TS, Basu N and Siddiqui HH: Anti-inflammatory activity of curcumin analogues. Indian J Med Res 75: 574-8, 1982.
    • (1982) Indian J Med Res , vol.75 , pp. 574-578
    • Rao, T.S.1    Basu, N.2    Siddiqui, H.H.3
  • 226
    • 0020450453 scopus 로고
    • Anti-inflammatory and irritant activities of curcumin analogues in rats
    • Mukhopadhyay A Basu N, Ghatak N and Gujral PK: Anti-inflammatory and irritant activities of curcumin analogues in rats. Agents Actions 12: 508-15, 1982.
    • (1982) Agents Actions , vol.12 , pp. 508-515
    • Mukhopadhyay, A.1    Basu, N.2    Ghatak, N.3    Gujral, P.K.4
  • 227
    • 0022021733 scopus 로고
    • Modification of certain inflammation-induced biochemical changes by curcumin
    • Srivastava R and Srimal RC: Modification of certain inflammation-induced biochemical changes by curcumin. Indian J Med Res 81: 215-23, 1985.
    • (1985) Indian J Med Res , vol.81 , pp. 215-223
    • Srivastava, R.1    Srimal, R.C.2
  • 228
    • 0028604321 scopus 로고
    • Studies on anti-inflammatory activity of spice principles and dietary n-3 polyunsaturated fatty acids on carrageenan-induced inflammation in rats
    • Reddy AC and Lokesh BR: Studies on anti-inflammatory activity of spice principles and dietary n-3 polyunsaturated fatty acids on carrageenan-induced inflammation in rats. Ann Nutr Metab 38: 349-58, 1994.
    • (1994) Ann Nutr Metab , vol.38 , pp. 349-358
    • Reddy, A.C.1    Lokesh, B.R.2
  • 229
    • 0030662046 scopus 로고    scopus 로고
    • Effect of curcumin and capsaicin on arachidonic acid metabolism and lysosomal enzyme secretion by rat peritoneal macrophages
    • Joe B and Lokesh BR: Effect of curcumin and capsaicin on arachidonic acid metabolism and lysosomal enzyme secretion by rat peritoneal macrophages. Lipids 32: 1173-80, 1997.
    • (1997) Lipids , vol.32 , pp. 1173-1180
    • Joe, B.1    Lokesh, B.R.2
  • 230
    • 0023193431 scopus 로고
    • In vitro antimutagenicity of curcumin against environmental mutagens
    • Nagabhushan M, Amonkar AJ and Bhide SV: In vitro antimutagenicity of curcumin against environmental mutagens. Food Chem Toxicol 25: 545-7, 1987.
    • (1987) Food Chem Toxicol , vol.25 , pp. 545-547
    • Nagabhushan, M.1    Amonkar, A.J.2    Bhide, S.V.3
  • 231
    • 0023199491 scopus 로고
    • Lipid peroxide induced DNA damage: Protection by turmeric (Curcuma longa)
    • Shalini VK and Srinivas L: Lipid peroxide induced DNA damage: protection by turmeric (Curcuma longa). Mol Cell Biochem 77: 3-10, 1987.
    • (1987) Mol Cell Biochem , vol.77 , pp. 3-10
    • Shalini, V.K.1    Srinivas, L.2
  • 232
    • 0025299786 scopus 로고
    • Fuel smoke condensate induced DNA damage in human lymphocytes and protection by turmeric (Curcuma longa)
    • Shalini VK and Srinivas L: Fuel smoke condensate induced DNA damage in human lymphocytes and protection by turmeric (Curcuma longa). Mol Cell Biochem 95: 21-30, 1990.
    • (1990) Mol Cell Biochem , vol.95 , pp. 21-30
    • Shalini, V.K.1    Srinivas, L.2
  • 233
    • 0025360746 scopus 로고
    • Sardjoko Vermeulen N.P. Cytotoxic and cytoprotective activities of curcumin. Effects on paracetamol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes
    • Donatus IA, Sardjoko and Vermeulen NP: Cytotoxic and cytoprotective activities of curcumin. Effects on paracetamol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes. Biochem Pharmacol 39: 1869-75, 1990.
    • (1990) Biochem Pharmacol , vol.39 , pp. 1869-1875
    • Donatus, I.A.1
  • 234
    • 0025887842 scopus 로고
    • DNA damage by smoke: Protection by turmeric and other inhibitors of ROS
    • Srinivas L and Shalini VK: DNA damage by smoke: protection by turmeric and other inhibitors of ROS. Free Radic Biol Med 11: 277-83, 1991.
    • (1991) Free Radic Biol Med , vol.11 , pp. 277-283
    • Srinivas, L.1    Shalini, V.K.2
  • 235
    • 0026659471 scopus 로고
    • Protective role of aqueous turmeric extract against mutagenicity of direct-acting carcinogens as well as benzo [alpha] pyrene-induced genotoxicity and carcinogenicity
    • Azuine MA, Kayal JJ and Bhide SV: Protective role of aqueous turmeric extract against mutagenicity of direct-acting carcinogens as well as benzo [alpha] pyrene-induced genotoxicity and carcinogenicity. J Cancer Res Clin Oncol 118: 447-52, 1992.
    • (1992) J Cancer Res Clin Oncol , vol.118 , pp. 447-452
    • Azuine, M.A.1    Kayal, J.J.2    Bhide, S.V.3
  • 236
    • 0027448517 scopus 로고
    • Protective effects of chlorogenic acid, curcumin and beta-carotene against gamma-radiation-induced in vivo chromosomal damage
    • Abraham SK, Sarma L and Kesavan PC: Protective effects of chlorogenic acid, curcumin and beta-carotene against gamma-radiation-induced in vivo chromosomal damage. Mutat Res 303: 109-12, 1993.
    • (1993) Mutat Res , vol.303 , pp. 109-112
    • Abraham, S.K.1    Sarma, L.2    Kesavan, P.C.3
  • 238
    • 0028973218 scopus 로고
    • Inhibitory effect of curcumin on SOS functions induced by UV irradiation
    • Oda Y: Inhibitory effect of curcumin on SOS functions induced by UV irradiation. Mutat Res 348: 67-73, 1995.
    • (1995) Mutat Res , vol.348 , pp. 67-73
    • Oda, Y.1
  • 239
    • 0029100868 scopus 로고
    • Effects of curcumin on the formation of benzo[a]pyrene derived DNA adducts in vitro
    • Deshpande SS and Maru GB: Effects of curcumin on the formation of benzo[a]pyrene derived DNA adducts in vitro. Cancer Lett 96: 71-80, 1995.
    • (1995) Cancer Lett , vol.96 , pp. 71-80
    • Deshpande, S.S.1    Maru, G.B.2
  • 240
    • 0030582419 scopus 로고    scopus 로고
    • Antimutagenic and anticarcinogenic activity of natural and synthetic curcuminoids
    • Anto RJ, George J, Babu KV, Rajasekharan KN and Kuttan R: Antimutagenic and anticarcinogenic activity of natural and synthetic curcuminoids. Mutat Res 370: 127-31, 1996.
    • (1996) Mutat Res , vol.370 , pp. 127-131
    • Anto, R.J.1    George, J.2    Babu, K.V.3    Rajasekharan, K.N.4    Kuttan, R.5
  • 241
    • 0030906612 scopus 로고    scopus 로고
    • Protective effect of food additives on aflatoxin-induced mutagenicity and hepatocarcinogenicity
    • Soni KB, Lahiri M, Chackradeo P, Bhide SV and Kuttan R: Protective effect of food additives on aflatoxin-induced mutagenicity and hepatocarcinogenicity. Cancer Lett 115: 129-33, 1997.
    • (1997) Cancer Lett , vol.115 , pp. 129-133
    • Soni, K.B.1    Lahiri, M.2    Chackradeo, P.3    Bhide, S.V.4    Kuttan, R.5
  • 242
    • 0032512698 scopus 로고    scopus 로고
    • Strand scission in DNA induced by curcumin in the presence of Cu(II)
    • Ahsan H and Hadi SM: Strand scission in DNA induced by curcumin in the presence of Cu(II). Cancer Lett 124: 23-30, 1998.
    • (1998) Cancer Lett , vol.124 , pp. 23-30
    • Ahsan, H.1    Hadi, S.M.2
  • 243
    • 0345490827 scopus 로고    scopus 로고
    • Modulatory effects of curcumin on the chromosomal damage induced by doxorubicin in Chinese hamster ovary cells
    • Antunes LM, Araujo MC, Dias FL and Takahashi CS: Modulatory effects of curcumin on the chromosomal damage induced by doxorubicin in Chinese hamster ovary cells. Teratog Carcinog Mutagen 19: 1-8, 1999.
    • (1999) Teratog Carcinog Mutagen , vol.19 , pp. 1-8
    • Antunes, L.M.1    Araujo, M.C.2    Dias, F.L.3    Takahashi, C.S.4
  • 244
    • 0035837588 scopus 로고    scopus 로고
    • Disparate effects of similar phenolic phytochemicals as inhibitors of oxidative damage to cellular DNA
    • Kelly MR, Xu J, Alexander KE and Loo G: Disparate effects of similar phenolic phytochemicals as inhibitors of oxidative damage to cellular DNA. Mutat Res 485: 309-18, 2001.
    • (2001) Mutat Res , vol.485 , pp. 309-318
    • Kelly, M.R.1    Xu, J.2    Alexander, K.E.3    Loo, G.4
  • 245
    • 0035105943 scopus 로고    scopus 로고
    • Protective effect of thiourea, a hydroxyl-radical scavenger, on curcumin-induced chromosomal aberrations in an in vitro mammalian cell system
    • Araujo MC, Antunes LM and Takahashi CS: Protective effect of thiourea, a hydroxyl-radical scavenger, on curcumin-induced chromosomal aberrations in an in vitro mammalian cell system. Teratog Carcinog Mutagen 21: 175-80, 2001.
    • (2001) Teratog Carcinog Mutagen , vol.21 , pp. 175-180
    • Araujo, M.C.1    Antunes, L.M.2    Takahashi, C.S.3
  • 246
    • 0037182806 scopus 로고    scopus 로고
    • Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells
    • Holy JM: Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells. Mutat Res 518: 71-84, 2002.
    • (2002) Mutat Res , vol.518 , pp. 71-84
    • Holy, J.M.1
  • 247
    • 0037170662 scopus 로고    scopus 로고
    • Antimutagenic potential of curcumin on chromosomal aberrations in Wistar rats
    • Shukla Y, Arora A and Taneja P: Antimutagenic potential of curcumin on chromosomal aberrations in Wistar rats. Mutat Res 515: 197-202, 2002.
    • (2002) Mutat Res , vol.515 , pp. 197-202
    • Shukla, Y.1    Arora, A.2    Taneja, P.3
  • 248
    • 0035997266 scopus 로고    scopus 로고
    • Relative contribution of NF-kappaB and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbate of the UVB-induced cytokine expression by keratinocytes
    • Grandjean-Laquerriere A, Gangloff SC, Le Naour R, Trentesaux C, Hornebeck W and Guenounou M: Relative contribution of NF-kappaB and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbate of the UVB-induced cytokine expression by keratinocytes. Cytokine 18: 168-77, 2002.
    • (2002) Cytokine , vol.18 , pp. 168-177
    • Grandjean-Laquerriere, A.1    Gangloff, S.C.2    Le Naour, R.3    Trentesaux, C.4    Hornebeck, W.5    Guenounou, M.6
  • 249
    • 0029768740 scopus 로고    scopus 로고
    • Protective effect of curcumin, ellagic acid and bixin on radiation induced toxicity
    • Thresiamma KC, George J and Kuttan R: Protective effect of curcumin, ellagic acid and bixin on radiation induced toxicity. Indian J Exp Biol 34: 845-7, 1996.
    • (1996) Indian J Exp Biol , vol.34 , pp. 845-847
    • Thresiamma, K.C.1    George, J.2    Kuttan, R.3
  • 250
    • 0032435352 scopus 로고    scopus 로고
    • Protective effect of curcumin, ellagic acid and bixin on radiation induced genotoxicity
    • Thresiamma KC, George J and Kuttan R: Protective effect of curcumin, ellagic acid and bixin on radiation induced genotoxicity. J Exp Clin Cancer Res 17: 431-4, 1998.
    • (1998) J Exp Clin Cancer Res , vol.17 , pp. 431-434
    • Thresiamma, K.C.1    George, J.2    Kuttan, R.3
  • 251
    • 0345059224 scopus 로고    scopus 로고
    • Potentiation by turmeric and curcumin of gamma-radiation-induced chromosome aberrations in Chinese hamster ovary cells
    • Araujo MC, Dias FL and Takahashi CS: Potentiation by turmeric and curcumin of gamma-radiation-induced chromosome aberrations in Chinese hamster ovary cells. Teratog Carcinog Mutagen 19: 9-18, 1999.
    • (1999) Teratog Carcinog Mutagen , vol.19 , pp. 9-18
    • Araujo, M.C.1    Dias, F.L.2    Takahashi, C.S.3
  • 252
    • 0035975683 scopus 로고    scopus 로고
    • Protection of radiation-induced protein damage by curcumin
    • Kapoor S and Priyadarsini KI: Protection of radiation-induced protein damage by curcumin. Biophys Chem 92: 119-26, 2001.
    • (2001) Biophys Chem , vol.92 , pp. 119-126
    • Kapoor, S.1    Priyadarsini, K.I.2
  • 253
    • 0035662942 scopus 로고    scopus 로고
    • Modulation of radiation-induced protein kinase C activity by phenolics
    • Varadkar P, Dubey P, Krishna M and Verma N: Modulation of radiation-induced protein kinase C activity by phenolics. J Radiol Prot 21: 361-70, 2001.
    • (2001) J Radiol Prot , vol.21 , pp. 361-370
    • Varadkar, P.1    Dubey, P.2    Krishna, M.3    Verma, N.4
  • 254
    • 0035064895 scopus 로고    scopus 로고
    • Effect of ultraviolet A on ornithine decarboxylase and metallothionein gene expression in mouse skin
    • Oguro T and Yoshida T: Effect of ultraviolet A on ornithine decarboxylase and metallothionein gene expression in mouse skin. Photodermatol Photoimmunol Photomed 17: 71-8, 2001.
    • (2001) Photodermatol Photoimmunol Photomed , vol.17 , pp. 71-78
    • Oguro, T.1    Yoshida, T.2
  • 255
    • 0037044179 scopus 로고    scopus 로고
    • Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line
    • Ramachandran C, Fonseca HB, Jhabvala P, Escalon EA and Melnick SJ: Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line. Cancer Lett 184: 1-6, 2002.
    • (2002) Cancer Lett , vol.184 , pp. 1-6
    • Ramachandran, C.1    Fonseca, H.B.2    Jhabvala, P.3    Escalon, E.A.4    Melnick, S.J.5
  • 256
    • 0018222291 scopus 로고
    • The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the rat
    • Holder GM, Plummer JL and Ryan AJ: The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the rat. Xenobiotica 8: 761-8, 1978.
    • (1978) Xenobiotica , vol.8 , pp. 761-768
    • Holder, G.M.1    Plummer, J.L.2    Ryan, A.J.3
  • 258
    • 0018873182 scopus 로고
    • Absorption and tissue distribution of curcumin in rats
    • Ravindranath V and Chandrasekhara N: Absorption and tissue distribution of curcumin in rats. Toxicology 16: 259-65, 1980.
    • (1980) Toxicology , vol.16 , pp. 259-265
    • Ravindranath, V.1    Chandrasekhara, N.2
  • 259
    • 0019421988 scopus 로고
    • In vitro studies on the intestinal absorption of curcumin in rats
    • Ravindranath V and Chandrasekhara N: In vitro studies on the intestinal absorption of curcumin in rats. Toxicology 20: 251-7, 1981.
    • (1981) Toxicology , vol.20 , pp. 251-257
    • Ravindranath, V.1    Chandrasekhara, N.2
  • 260
    • 0020067035 scopus 로고
    • Metabolism of curcumin-studies with [3H]curcumin
    • Ravindranath V and Chandrasekhara N: Metabolism of curcumin - studies with [3H]curcumin. Toxicology 22: 337-44, 1981.
    • (1981) Toxicology , vol.22 , pp. 337-344
    • Ravindranath, V.1    Chandrasekhara, N.2
  • 261
    • 0031860081 scopus 로고    scopus 로고
    • Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers
    • Shoba G, Joy D, Joseph T, Majeed M, Rajendran R and Srinivas PS: Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med 64: 353-6, 1998.
    • (1998) Planta Med , vol.64 , pp. 353-356
    • Shoba, G.1    Joy, D.2    Joseph, T.3    Majeed, M.4    Rajendran, R.5    Srinivas, P.S.6
  • 262
    • 0032926620 scopus 로고    scopus 로고
    • Biotransformation of curcumin through reduction and glucuronidation in mice
    • Pan MH, Huang TM and Lin JK: Biotransformation of curcumin through reduction and glucuronidation in mice. Drug Metab Dispos 27: 486-94, 1999.
    • (1999) Drug Metab Dispos , vol.27 , pp. 486-494
    • Pan, M.H.1    Huang, T.M.2    Lin, J.K.3
  • 263
    • 0033161171 scopus 로고    scopus 로고
    • Epidemiology of digestive tract cancers in India. V. Large and small bowel
    • Mohandas KM and Desai DC: Epidemiology of digestive tract cancers in India. V. Large and small bowel. Indian J Gastroenterol 18: 118-21, 1999.
    • (1999) Indian J Gastroenterol , vol.18 , pp. 118-121
    • Mohandas, K.M.1    Desai, D.C.2
  • 265
    • 0032833681 scopus 로고    scopus 로고
    • Systemic administration of the NF-kappaB inhibitor curcumin stimulates muscle regeneration after traumatic injury
    • Thaloor D, Miller KJ, Gephart J, Mitchell PO and Pavlath GK: Systemic administration of the NF-kappaB inhibitor curcumin stimulates muscle regeneration after traumatic injury. Am J Physiol 277: C320-9, 1999.
    • (1999) Am J Physiol , vol.277
    • Thaloor, D.1    Miller, K.J.2    Gephart, J.3    Mitchell, P.O.4    Pavlath, G.K.5
  • 266
    • 0034492793 scopus 로고    scopus 로고
    • Recent studies on the biofunctions and biotransformations of curcumin
    • Lin JK, Pan MH and Lin-Shiau SY: Recent studies on the biofunctions and biotransformations of curcumin. Biofactors 13: 153-8, 2000.
    • (2000) Biofactors , vol.13 , pp. 153-158
    • Lin, J.K.1    Pan, M.H.2    Lin-Shiau, S.Y.3
  • 271
    • 0035114277 scopus 로고    scopus 로고
    • Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production
    • Ireson C, Orr S, Jones DJ, Verschoyle R, Lim CK, Luo JL, Howells L, Plummer S, Jukes R, Williams M, Steward WP and Gescher A: Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production. Cancer Res 61: 1058-64, 2001.
    • (2001) Cancer Res , vol.61 , pp. 1058-1064
    • Ireson, C.1    Orr, S.2    Jones, D.J.3    Verschoyle, R.4    Lim, C.K.5    Luo, J.L.6    Howells, L.7    Plummer, S.8    Jukes, R.9    Williams, M.10    Steward, W.P.11    Gescher, A.12
  • 273
    • 0036480752 scopus 로고    scopus 로고
    • Pre-clinical and early-phase clinical studies of curcumin as chemopreventive agent for endemic cancers in Taiwan
    • Hsu CH, Chuang SE, Hergenhahn M, Kuo ML, Lin JK, Hsieh CY and Cheng AL: Pre-clinical and early-phase clinical studies of curcumin as chemopreventive agent for endemic cancers in Taiwan. Gan To Kagaku Ryoho 29 Suppl 1: 194-200, 2002.
    • (2002) Gan To Kagaku Ryoho , vol.29 , Issue.SUPPL. 1 , pp. 194-200
    • Hsu, C.H.1    Chuang, S.E.2    Hergenhahn, M.3    Kuo, M.L.4    Lin, J.K.5    Hsieh, C.Y.6    Cheng, A.L.7
  • 276
    • 0022357855 scopus 로고
    • Potential anticancer activity of turmeric (Curcuma longa)
    • Kuttan R, Bhanumathy P, Nirmala K and George MC: Potential anticancer activity of turmeric (Curcuma longa). Cancer Lett 29: 197-202, 1985.
    • (1985) Cancer Lett , vol.29 , pp. 197-202
    • Kuttan, R.1    Bhanumathy, P.2    Nirmala, K.3    George, M.C.4
  • 277
    • 0023130877 scopus 로고
    • Turmeric and curcumin as topical agents in cancer therapy
    • Kuttan R, Sudheeran PC and Josph CD: Turmeric and curcumin as topical agents in cancer therapy. Tumori 73: 29-31, 1987.
    • (1987) Tumori , vol.73 , pp. 29-31
    • Kuttan, R.1    Sudheeran, P.C.2    Josph, C.D.3
  • 278
    • 0023790908 scopus 로고
    • Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate
    • Huang MT, Smart RC, Wong CQ and Conney AH: Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate. Cancer Res 48: 5941-6, 1988.
    • (1988) Cancer Res , vol.48 , pp. 5941-5946
    • Huang, M.T.1    Smart, R.C.2    Wong, C.Q.3    Conney, A.H.4
  • 279
    • 0024826358 scopus 로고
    • Inhibition of chemical carcinogenesis by curcumin
    • Soudamini KK and Kuttan R: Inhibition of chemical carcinogenesis by curcumin. J Ethnopharmacol 27: 227-33, 1989.
    • (1989) J Ethnopharmacol , vol.27 , pp. 227-233
    • Soudamini, K.K.1    Kuttan, R.2
  • 280
    • 0026785528 scopus 로고
    • Reversal of aflatoxin induced liver damage by turmeric and curcumin
    • Soni KB, Rajan A and Kuttan R: Reversal of aflatoxin induced liver damage by turmeric and curcumin. Cancer Lett 66: 115-21, 1992.
    • (1992) Cancer Lett , vol.66 , pp. 115-121
    • Soni, K.B.1    Rajan, A.2    Kuttan, R.3
  • 281
    • 0026615189 scopus 로고
    • Inhibitory effects of curcumin on tumor initiation by benzo [a]pyrene and 7,12dimethylbenz[a]anthracene
    • Huang MT, Wang ZY, Georgiadis CA, Laskin JD and Conney AH: Inhibitory effects of curcumin on tumor initiation by benzo [a]pyrene and 7,12dimethylbenz[a]anthracene. Carcinogenesis 13: 2183-6, 1992.
    • (1992) Carcinogenesis , vol.13 , pp. 2183-2186
    • Huang, M.T.1    Wang, Z.Y.2    Georgiadis, C.A.3    Laskin, J.D.4    Conney, A.H.5
  • 282
    • 0028073507 scopus 로고
    • Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice
    • Huang MT, Lou YR, Ma W, Newmark HL, Reuhl KR and Conney AH: Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice. Cancer Res 54: 5841-7, 1994.
    • (1994) Cancer Res , vol.54 , pp. 5841-5847
    • Huang, M.T.1    Lou, Y.R.2    Ma, W.3    Newmark, H.L.4    Reuhl, K.R.5    Conney, A.H.6
  • 283
    • 0026540445 scopus 로고
    • Curcumin as an inhibitor of cancer
    • Nagabhushan M and Bhide SV: Curcumin as an inhibitor of cancer. J Am Coll Nutr 11: 192-8, 1992.
    • (1992) J Am Coll Nutr , vol.11 , pp. 192-198
    • Nagabhushan, M.1    Bhide, S.V.2
  • 284
    • 0026553336 scopus 로고
    • Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice
    • Azuine MA and Bhide SV: Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice. Nutr Cancer 17: 77-83, 1992.
    • (1992) Nutr Cancer , vol.17 , pp. 77-83
    • Azuine, M.A.1    Bhide, S.V.2
  • 285
    • 0026748972 scopus 로고
    • Protective single/combined treatment with betel leaf and turmeric against methyl (acetoxymethyl) nitrosamine-induced hamster oral carcinogenesis
    • Azuine MA and Bhide SV: Protective single/combined treatment with betel leaf and turmeric against methyl (acetoxymethyl) nitrosamine-induced hamster oral carcinogenesis. Int J Cancer 51: 412-5, 1992.
    • (1992) Int J Cancer , vol.51 , pp. 412-415
    • Azuine, M.A.1    Bhide, S.V.2
  • 286
    • 0027333082 scopus 로고
    • Inhibition by dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in the rat colon
    • Rao CV, Simi B and Reddy BS: Inhibition by dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in the rat colon. Carcinogenesis 14: 2219-25, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 2219-2225
    • Rao, C.V.1    Simi, B.2    Reddy, B.S.3
  • 287
    • 0027189562 scopus 로고
    • Inhibitory effect of curcumin on 120-tetradecanoylphorbol-13-acetate-induced increase in ornithine decarboxylase mRNA in mouse epidermis
    • Lu YP, Chang RL, Huang MT and Conney AH: Inhibitory effect of curcumin on 120-tetradecanoylphorbol-13-acetate-induced increase in ornithine decarboxylase mRNA in mouse epidermis. Carcinogenesis 14: 293-7, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 293-297
    • Lu, Y.P.1    Chang, R.L.2    Huang, M.T.3    Conney, A.H.4
  • 288
    • 0027934285 scopus 로고
    • Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: Comparison with the protective effect of beta-carotene
    • Tanaka T, Makita H, Ohnishi M, Hirose Y, Wang A, Mori H, Satoh K, Hara A and Ogawa H: Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: comparison with the protective effect of beta-carotene. Cancer Res 54: 4653-9, 1994.
    • (1994) Cancer Res , vol.54 , pp. 4653-4659
    • Tanaka, T.1    Makita, H.2    Ohnishi, M.3    Hirose, Y.4    Wang, A.5    Mori, H.6    Satoh, K.7    Hara, A.8    Ogawa, H.9
  • 289
    • 0028558777 scopus 로고
    • Adjuvant chemoprevention of experimental cancer: Catechin and dietary turmeric in forestomach and oral cancer models
    • Azuine MA and Bhide SV: Adjuvant chemoprevention of experimental cancer: catechin and dietary turmeric in forestomach and oral cancer models. J Ethnopharmacol 44: 211-7, 1994.
    • (1994) J Ethnopharmacol , vol.44 , pp. 211-217
    • Azuine, M.A.1    Bhide, S.V.2
  • 290
    • 0028267050 scopus 로고
    • In vitro studies on chemoprotective effect of Pumark against benzo(a)pyrene-induced chromosomal damage in human lymphocytes
    • Ghaisas SID and Bhide SV: In vitro studies on chemoprotective effect of Pumark against benzo(a)pyrene-induced chromosomal damage in human lymphocytes. Cell Biol Int 18: 21-7, 1994.
    • (1994) Cell Biol Int , vol.18 , pp. 21-27
    • Ghaisas, S.I.D.1    Bhide, S.V.2
  • 291
    • 0028872989 scopus 로고
    • Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound
    • Rao CV, Rivenson A, Simi B and Reddy BS: Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res 55: 259-66, 1995.
    • (1995) Cancer Res , vol.55 , pp. 259-266
    • Rao, C.V.1    Rivenson, A.2    Simi, B.3    Reddy, B.S.4
  • 292
  • 293
    • 0028800250 scopus 로고
    • Effects of curcumin, demethoxycurcumin, bisdemethexycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion
    • Huang MT, Ma W, Lu YP, Chang RL, Fisher C, Manchand PS, Newmark HL and Conney AH: Effects of curcumin, demethoxycurcumin, bisdemethexycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion. Carcinogenesis 16: 2493-7, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 2493-2497
    • Huang, M.T.1    Ma, W.2    Lu, Y.P.3    Chang, R.L.4    Fisher, C.5    Manchand, P.S.6    Newmark, H.L.7    Conney, A.H.8
  • 295
    • 0029918159 scopus 로고    scopus 로고
    • Inhibition of 7,12dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis and DMBA-DNA adduct formation by curcumin
    • Singletary K, MacDonald C, Wallig M and Fisher C: Inhibition of 7,12dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis and DMBA-DNA adduct formation by curcumin. Cancer Lett 103: 137-41, 1996.
    • (1996) Cancer Lett , vol.103 , pp. 137-141
    • Singletary, K.1    MacDonald, C.2    Wallig, M.3    Fisher, C.4
  • 296
    • 0030459109 scopus 로고    scopus 로고
    • Enhancing effect of ultraviolet A on ornithine decarboxylase induction and dermatitis evoked by 12-otetradecanoylphorbol-13-acetate and its inhibition by curcumin in mouse skin
    • Ishizaki C, Oguro T, Yoshida T, Wen CQ, Sueki H and Iijima M: Enhancing effect of ultraviolet A on ornithine decarboxylase induction and dermatitis evoked by 12-otetradecanoylphorbol-13-acetate and its inhibition by curcumin in mouse skin. Dermatology 193: 311-7, 1996.
    • (1996) Dermatology , vol.193 , pp. 311-317
    • Ishizaki, C.1    Oguro, T.2    Yoshida, T.3    Wen, C.Q.4    Sueki, H.5    Iijima, M.6
  • 297
    • 0031418195 scopus 로고    scopus 로고
    • Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis
    • Huang MT, Ma W, Yen P, Xie JG, Han J, Frenkel K, Grunberger D and Conney AH: Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis. Carcinogenesis 18: 83-8, 1997.
    • (1997) Carcinogenesis , vol.18 , pp. 83-88
    • Huang, M.T.1    Ma, W.2    Yen, P.3    Xie, J.G.4    Han, J.5    Frenkel, K.6    Grunberger, D.7    Conney, A.H.8
  • 299
    • 0031586742 scopus 로고    scopus 로고
    • Effects of ntritriacontane-16,18-dione, curcumin, chlorphyllin, dihydroguaiaretic acid, tannic acid and phytic acid on the initiation stage in a rat multi-organ carcinogenesis model
    • Takaba K, Hirose M, Yoshida Y, Kimura J, Ito N and Shirai T: Effects of ntritriacontane-16,18-dione, curcumin, chlorphyllin, dihydroguaiaretic acid, tannic acid and phytic acid on the initiation stage in a rat multi-organ carcinogenesis model. Cancer Lett 113: 39-46, 1997.
    • (1997) Cancer Lett , vol.113 , pp. 39-46
    • Takaba, K.1    Hirose, M.2    Yoshida, Y.3    Kimura, J.4    Ito, N.5    Shirai, T.6
  • 300
    • 0032536140 scopus 로고    scopus 로고
    • Chemopreventive efficacy of curcumin-free aqueous turmeric extract in 7,12-dimethylbenz [a]anthracene-induced rat mammary tumorigenesis
    • Deshpande SS, Ingle AD and Maru GB: Chemopreventive efficacy of curcumin-free aqueous turmeric extract in 7,12-dimethylbenz [a]anthracene-induced rat mammary tumorigenesis. Cancer Lett 123: 35-40, 1998.
    • (1998) Cancer Lett , vol.123 , pp. 35-40
    • Deshpande, S.S.1    Ingle, A.D.2    Maru, G.B.3
  • 301
    • 0031691297 scopus 로고    scopus 로고
    • Mechanism of inhibition of benzo[a]pyrene-induced forestomach cancer in mice by dietary curcumin
    • Singh SV, Hu X, Srivastava SK, Singh M, Xia H, Orchard JL and Zaren HA: Mechanism of inhibition of benzo[a]pyrene-induced forestomach cancer in mice by dietary curcumin. Carcinogenesis 19: 1357-60, 1998.
    • (1998) Carcinogenesis , vol.19 , pp. 1357-1360
    • Singh, S.V.1    Hu, X.2    Srivastava, S.K.3    Singh, M.4    Xia, H.5    Orchard, J.L.6    Zaren, H.A.7
  • 302
    • 0031968785 scopus 로고    scopus 로고
    • Retardation of experimental tumorigenesis and reduction in DNA adducts by turmeric and curcumin
    • Krishnaswamy K, Goud VK, Sesikeran B, Mukundan MA and Krishna TP: Retardation of experimental tumorigenesis and reduction in DNA adducts by turmeric and curcumin. Nutr Cancer 30: 163-6, 1998.
    • (1998) Nutr Cancer , vol.30 , pp. 163-166
    • Krishnaswamy, K.1    Goud, V.K.2    Sesikeran, B.3    Mukundan, M.A.4    Krishna, T.P.5
  • 303
    • 0031799304 scopus 로고    scopus 로고
    • Mechanisms of anticarcinogenic properties of curcumin: The effect of curcumin on glutathione linked detoxification enzymes in rat liver
    • Piper JT, Singhal SS, Salameh MS, Torman RT, Awasthi YC and Awasthi S: Mechanisms of anticarcinogenic properties of curcumin: the effect of curcumin on glutathione linked detoxification enzymes in rat liver. Int J Biochem Cell Biol 30: 445-56, 1998.
    • (1998) Int J Biochem Cell Biol , vol.30 , pp. 445-456
    • Piper, J.T.1    Singhal, S.S.2    Salameh, M.S.3    Torman, R.T.4    Awasthi, Y.C.5    Awasthi, S.6
  • 305
    • 0031658361 scopus 로고    scopus 로고
    • Effect of dietary curcumin and dibenzoylmethane on formation of 7,12dimethylbenz[a]anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice
    • Huang MT, Lou YR, Xie JG, Ma W, Lu YP, Yen P, Zhu BT, Newmark H and Ho CT: Effect of dietary curcumin and dibenzoylmethane on formation of 7,12dimethylbenz[a]anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice. Carcinogenesis 19: 1697-700, 1998.
    • (1998) Carcinogenesis , vol.19 , pp. 1697-1700
    • Huang, M.T.1    Lou, Y.R.2    Xie, J.G.3    Ma, W.4    Lu, Y.P.5    Yen, P.6    Zhu, B.T.7    Newmark, H.8    Ho, C.T.9
  • 306
    • 0033082458 scopus 로고    scopus 로고
    • Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer
    • Kawamori T, Lubet R, Steele VE, Kelloff GJ, Kaskey RB, Rao CV and Reddy BS: Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer. Cancer Res 59: 597-601, 1999.
    • (1999) Cancer Res , vol.59 , pp. 597-601
    • Kawamori, T.1    Lubet, R.2    Steele, V.E.3    Kelloff, G.J.4    Kaskey, R.B.5    Rao, C.V.6    Reddy, B.S.7
  • 307
    • 0033062435 scopus 로고    scopus 로고
    • Chemoprevention by curcumin during the promotion stage of tumorigenesis of mammary gland in rats irradiated with gamma-rays
    • Inano H, Onoda M, Inafuku N, Kubota M, Kamada Y, Osawa T, Kobayashi H and Wakabayashi K: Chemoprevention by curcumin during the promotion stage of tumorigenesis of mammary gland in rats irradiated with gamma-rays. Carcinogenesis 20: 1011-8, 1999.
    • (1999) Carcinogenesis , vol.20 , pp. 1011-1018
    • Inano, H.1    Onoda, M.2    Inafuku, N.3    Kubota, M.4    Kamada, Y.5    Osawa, T.6    Kobayashi, H.7    Wakabayashi, K.8
  • 308
    • 0033255389 scopus 로고    scopus 로고
    • Evaluation of the potential of cancer chemopreventive activity mediated by inhibition of 12-O-tetradecanoylphorbol 13-acetate-induced ornithine decarboxylase activity
    • Lee SK, Pezzuto JM: Evaluation of the potential of cancer chemopreventive activity mediated by inhibition of 12-O-tetradecanoyl phorbol 13-acetate-induced ornithine decarboxylase activity. Arch Pharm Res 22: 559-64, 1999.
    • (1999) Arch Pharm Res , vol.22 , pp. 559-564
    • Lee, S.K.1    Pezzuto, J.M.2
  • 309
    • 0033106247 scopus 로고    scopus 로고
    • Dietary curcumin with cisplatin administration modulates tumour marker indices in experimental fibrosarcoma
    • Navis I, Sriganth P and Premalatha B: Dietary curcumin with cisplatin administration modulates tumour marker indices in experimental fibrosarcoma. Pharmacol Res 39: 175-9, 1999.
    • (1999) Pharmacol Res , vol.39 , pp. 175-179
    • Navis, I.1    Sriganth, P.2    Premalatha, B.3
  • 310
    • 0032774883 scopus 로고    scopus 로고
    • Anti-tumor promoting potential of naturally occurring diarylheptanoids structurally related to curcumin
    • Chun KS, Sohn Y, Kim HS, Kim OH, Park KK, Lee JM, Moon A, Lee SS and Surh YJ: Anti-tumor promoting potential of naturally occurring diarylheptanoids structurally related to curcumin. Mutat Res 428: 49-57, 1999.
    • (1999) Mutat Res , vol.428 , pp. 49-57
    • Chun, K.S.1    Sohn, Y.2    Kim, H.S.3    Kim, O.H.4    Park, K.K.5    Lee, J.M.6    Moon, A.7    Lee, S.S.8    Surh, Y.J.9
  • 311
    • 0032955892 scopus 로고    scopus 로고
    • Evaluation of butylated hydroxyanisole, myoinositol, curcumin, esculetin, resveratrol and lycopene as inhibitors of benzo[a]pyrene plus 4(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung turnorigenesis in A/J mice
    • Hecht SS, Kenney PM, Wang M, Trushin N, Agarwal S, Rao AV and Upadhyaya P: Evaluation of butylated hydroxyanisole, myoinositol, curcumin, esculetin, resveratrol and lycopene as inhibitors of benzo[a]pyrene plus 4(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung turnorigenesis in A/J mice. Cancer Lett 137: 123-30, 1999.
    • (1999) Cancer Lett , vol.137 , pp. 123-130
    • Hecht, S.S.1    Kenney, P.M.2    Wang, M.3    Trushin, N.4    Agarwal, S.5    Rao, A.V.6    Upadhyaya, P.7
  • 312
    • 0034113598 scopus 로고    scopus 로고
    • Inhibition of intestinal tumors by curcumin is associated with changes in the intestinal immune cell profile
    • Churchill M, Chadbum A, Bilinski RT and Bertagnolli MM: Inhibition of intestinal tumors by curcumin is associated with changes in the intestinal immune cell profile. J Surg Res 89: 169-75, 2000.
    • (2000) J Surg Res , vol.89 , pp. 169-175
    • Churchill, M.1    Chadbum, A.2    Bilinski, R.T.3    Bertagnolli, M.M.4
  • 314
    • 0033801316 scopus 로고    scopus 로고
    • Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in rats
    • Chuang SE, Cheng AL, Lin JK and Kuo ML: Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in rats. Food Chem Toxicol 38: 991-5, 2000.
    • (2000) Food Chem Toxicol , vol.38 , pp. 991-995
    • Chuang, S.E.1    Cheng, A.L.2    Lin, J.K.3    Kuo, M.L.4
  • 315
    • 0034662614 scopus 로고    scopus 로고
    • Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: Comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer
    • Mariadason JM, Comer GA and Augenlicht LH: Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer. Cancer Res 60: 4561-72, 2000.
    • (2000) Cancer Res , vol.60 , pp. 4561-4572
    • Mariadason, J.M.1    Comer, G.A.2    Augenlicht, L.H.3
  • 318
    • 0035178529 scopus 로고    scopus 로고
    • Inhibitory effects of naturally occurring compounds on aflatoxin B(1) biotransformation
    • Lee SE, Campbell BC, Molyneux RJ, Hasegawa S and Lee HS: Inhibitory effects of naturally occurring compounds on aflatoxin B(1) biotransformation. J Agric Food Chem 49: 5171-7, 2001.
    • (2001) J Agric Food Chem , vol.49 , pp. 5171-5177
    • Lee, S.E.1    Campbell, B.C.2    Molyneux, R.J.3    Hasegawa, S.4    Lee, H.S.5
  • 319
    • 0035140448 scopus 로고    scopus 로고
    • Effects of turmeric on the activities of benzo(a)pyrene-induced cytochrome P-450 isozymes
    • Thaphyal R, Deshpande SS and Maru GB: Effects of turmeric on the activities of benzo(a)pyrene-induced cytochrome P-450 isozymes. J Environ Pathol Toxicol Oncol 20: 59-63, 2001.
    • (2001) J Environ Pathol Toxicol Oncol , vol.20 , pp. 59-63
    • Thaphyal, R.1    Deshpande, S.S.2    Maru, G.B.3
  • 320
    • 0035572831 scopus 로고    scopus 로고
    • Chemopreventive effects of curcumin on glandular stomach carcinogenesis induced by N-methyl-N′-nitro-N-nitrosoguanidine and sodium chloride in rats
    • Ikezaki S, Nishikawa A, Furukawa F, Kudo K, Nakamura H, Tamura K and Mori H: Chemopreventive effects of curcumin on glandular stomach carcinogenesis induced by N-methyl-N′-nitro-N-nitrosoguanidine and sodium chloride in rats. Anticancer Res 21: 3407-11, 2001.
    • (2001) Anticancer Res , vol.21 , pp. 3407-3411
    • Ikezaki, S.1    Nishikawa, A.2    Furukawa, F.3    Kudo, K.4    Nakamura, H.5    Tamura, K.6    Mori, H.7
  • 321
    • 0035403609 scopus 로고    scopus 로고
    • Mechanistic studies on the inhibitory action of dietary dibenzoylmethane, a beta-diketone analogue of curcumin, on 7,12dimethylbenz[a]anthracene-induced mammary tumorigenesis
    • Lin CC, Ho CT and Huang MT: Mechanistic studies on the inhibitory action of dietary dibenzoylmethane, a beta-diketone analogue of curcumin, on 7,12dimethylbenz[a]anthracene-induced mammary tumorigenesis. Proc Natl Sci Counc Repub China B 25: 158-65, 2001.
    • (2001) Proc Natl Sci Counc Repub China B , vol.25 , pp. 158-165
    • Lin, C.C.1    Ho, C.T.2    Huang, M.T.3
  • 322
    • 3042652926 scopus 로고    scopus 로고
    • Inhibition of carcinogen induced c-Ha-ras and c-fos proto-oncogenes expression by dietary curcumin
    • Limtrakul Pn P, Anuchapreeda S, Lipigomgoson S and Dunn FW: Inhibition of carcinogen induced c-Ha-ras and c-fos proto-oncogenes expression by dietary curcumin. BMC Cancer 1: 1, 2001.
    • (2001) BMC Cancer , vol.1 , pp. 1
    • Limtrakul, P.N.P.1    Anuchapreeda, S.2    Lipigomgoson, S.3    Dunn, F.W.4
  • 323
    • 0034834008 scopus 로고    scopus 로고
    • Curcumin prevents intravesical tumor implantation of the MBT-2 tumor cell line in OH mice
    • Sindhwani P, Hampton JA, Baig MM, Keck R and Selman SH: Curcumin prevents intravesical tumor implantation of the MBT-2 tumor cell line in OH mice. J Urol 166: 1498-501, 2001.
    • (2001) J Urol , vol.166 , pp. 1498-1501
    • Sindhwani, P.1    Hampton, J.A.2    Baig, M.M.3    Keck, R.4    Selman, S.H.5
  • 324
    • 0035954823 scopus 로고    scopus 로고
    • Inhibition by dietary dibenzoylmethane of mammary gland proliferation, formation of DMBA-DNA adducts in mammary glands, and mammary tumorigenesis in Sencar mice
    • Lin CC, Lu YP, Lou YR, Ho CT, Newmark HH, MacDonald C, Singletary KW and Huang MT: Inhibition by dietary dibenzoylmethane of mammary gland proliferation, formation of DMBA-DNA adducts in mammary glands, and mammary tumorigenesis in Sencar mice. Cancer Lett 168: 125-32, 2001.
    • (2001) Cancer Lett , vol.168 , pp. 125-132
    • Lin, C.C.1    Lu, Y.P.2    Lou, Y.R.3    Ho, C.T.4    Newmark, H.H.5    MacDonald, C.6    Singletary, K.W.7    Huang, M.T.8
  • 325
    • 0035032279 scopus 로고    scopus 로고
    • Growth suppression of hamster flank organs by topical application of catechins, alizarin, curcumin, and myristoleic acid
    • Liao S, Lin J, Dang MT, Zhang H, Kao YH, Fukuchi J and Hiipakka RA: Growth suppression of hamster flank organs by topical application of catechins, alizarin, curcumin, and myristoleic acid. Arch Dermatol Res 293: 200-5, 2001.
    • (2001) Arch Dermatol Res , vol.293 , pp. 200-205
    • Liao, S.1    Lin, J.2    Dang, M.T.3    Zhang, H.4    Kao, Y.H.5    Fukuchi, J.6    Hiipakka, R.A.7
  • 326
    • 0035025724 scopus 로고    scopus 로고
    • Curcumin modifies Apc(min) apoptosis resistance and inhibits 2-amino 1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP) induced tumour formation in Apc(min) mice
    • Collett GP, Robson CN, Mathers JC and Campbell FC: curcumin modifies Apc(min) apoptosis resistance and inhibits 2-amino 1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP) induced tumour formation in Apc(min) mice. Carcinogenesis 22: 821-5, 2001.
    • (2001) Carcinogenesis , vol.22 , pp. 821-825
    • Collett, G.P.1    Robson, C.N.2    Mathers, J.C.3    Campbell, F.C.4
  • 327
    • 0036190104 scopus 로고    scopus 로고
    • The chemopreventive compound curcumin is an efficient inhibitor of Epstein-Barr virus BZLF1 transcription in Raji DR-LUC cells
    • Hergenhahn M, Soto U, Weninger A, Polack A, Hsu CH, Cheng AL and Rosl F: The chemopreventive compound curcumin is an efficient inhibitor of Epstein-Barr virus BZLF1 transcription in Raji DR-LUC cells. Mol Carcinog 33: 137-45, 2002.
    • (2002) Mol Carcinog , vol.33 , pp. 137-145
    • Hergenhahn, M.1    Soto, U.2    Weninger, A.3    Polack, A.4    Hsu, C.H.5    Cheng, A.L.6    Rosl, F.7
  • 328
    • 0036139798 scopus 로고    scopus 로고
    • Prevention of radiation-induced mammary tumors
    • Inano H and Onoda M: Prevention of radiation-induced mammary tumors. Int J Radiat Oncol Biol Phys 52: 212-23, 2002.
    • (2002) Int J Radiat Oncol Biol Phys , vol.52 , pp. 212-223
    • Inano, H.1    Onoda, M.2
  • 329
  • 330
    • 0026692173 scopus 로고
    • Effect of dietary curcumin and ascorbyl palmitate on azoxymethanol-induced colonic epithelial cell proliferation and focal areas of dysplasia
    • Huang MT, Deschner EE, Newmark HL, Wang ZY, Ferraro TA and Conney AH: Effect of dietary curcumin and ascorbyl palmitate on azoxymethanol-induced colonic epithelial cell proliferation and focal areas of dysplasia. Cancer Lett 64: 117-21, 1992.
    • (1992) Cancer Lett , vol.64 , pp. 117-121
    • Huang, M.T.1    Deschner, E.E.2    Newmark, H.L.3    Wang, Z.Y.4    Ferraro, T.A.5    Conney, A.H.6
  • 331
    • 0036643963 scopus 로고    scopus 로고
    • Radioprotective action of curcumin extracted from Curcuma longa Linn: Inhibitory effect on formation of urinary 8-hydroxy-2′deoxyguanosine, tumorigenesis, but not mortality, induced by gamma-ray irradiation
    • Inano H and Onoda M: Radioprotective action of curcumin extracted from Curcuma longa Linn: inhibitory effect on formation of urinary 8-hydroxy-2′deoxyguanosine, tumorigenesis, but not mortality, induced by gamma-ray irradiation. Int J Radiat Oncol Biol Phys 53: 735-43, 2002.
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 735-743
    • Inano, H.1    Onoda, M.2
  • 333
    • 0035838123 scopus 로고    scopus 로고
    • Curcumin, a natural product present in turmeric, decreases tumor growth but does not behave as an anticachectic compound in a rat model
    • Busquets S, Carbo N, Almendro V, Quiles MT, Lopez-Soriano FJ and Argiles JM: Curcumin, a natural product present in turmeric, decreases tumor growth but does not behave as an anticachectic compound in a rat model. Cancer Lett 167: 33-8, 2001.
    • (2001) Cancer Lett , vol.167 , pp. 33-38
    • Busquets, S.1    Carbo, N.2    Almendro, V.3    Quiles, M.T.4    Lopez-Soriano, F.J.5    Argiles, J.M.6
  • 334
    • 0035370750 scopus 로고    scopus 로고
    • Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo
    • Dorai T, Cao YC, Dorai B, Buttyan R and Katz AE: Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo. Prostate 47: 293-303, 2001.
    • (2001) Prostate , vol.47 , pp. 293-303
    • Dorai, T.1    Cao, Y.C.2    Dorai, B.3    Buttyan, R.4    Katz, A.E.5
  • 335
    • 0029112154 scopus 로고
    • Inhibition of lung metastasis in mice induced by B16F10 melanoma cells by polyphenolic compounds
    • Menon LG, Kuttan R and Kuttan G: Inhibition of lung metastasis in mice induced by B16F10 melanoma cells by polyphenolic compounds. Cancer Lett 95: 221-5, 1995.
    • (1995) Cancer Lett , vol.95 , pp. 221-225
    • Menon, L.G.1    Kuttan, R.2    Kuttan, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.