메뉴 건너뛰기




Volumn 1, Issue 7, 2008, Pages 568-576

Dose-dependent inhibition of tobacco smoke carcinogen-induced lung tumorigenesis in A/J mice by indole-3-carbinol

Author keywords

[No Author keywords available]

Indexed keywords

3 INDOLEMETHANOL; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; 4-(N-METHYL-N-NITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE; ANTINEOPLASTIC AGENT; BENZO[A]PYRENE; CARCINOGEN; INDOLE DERIVATIVE; INDOLE-3-CARBINOL; NITROSAMINE;

EID: 62349095729     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-08-0064     Document Type: Article
Times cited : (34)

References (41)
  • 3
    • 0034917171 scopus 로고    scopus 로고
    • The less harmful cigarette: A controversial issue. A tribute to Ernst L. Wynder
    • Hoffmann D, Hoffmann I, El Bayoumy K. The less harmful cigarette: a controversial issue. A tribute to Ernst L. Wynder. Chem Res Toxicol 2001;14:767-90.
    • (2001) Chem Res Toxicol , vol.14 , pp. 767-790
    • Hoffmann, D.1    Hoffmann, I.2    El Bayoumy, K.3
  • 4
    • 20144369093 scopus 로고    scopus 로고
    • Tobacco smoke and involuntary smoking
    • IARC. Lyon: IARC Press
    • IARC. Tobacco smoke and involuntary smoking. In: IARC monographs on the evaluation of carcinogenic risks to humans. Lyon: IARC Press; 2004. vol. 83. p. 53-119.
    • (2004) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , vol.83 , pp. 53-119
  • 5
    • 0033591845 scopus 로고    scopus 로고
    • Tobacco smoke carcinogens and lung cancer
    • Hecht SS. Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 1999;91:1194-210.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1194-1210
    • Hecht, S.S.1
  • 6
    • 0031831381 scopus 로고    scopus 로고
    • Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines
    • Hecht SS. Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines. Chem Res Toxicol 1998;11:560-603.
    • (1998) Chem Res Toxicol , vol.11 , pp. 560-603
    • Hecht, S.S.1
  • 7
    • 0034997385 scopus 로고    scopus 로고
    • Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung
    • Malkinson AK. Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung. Lung Cancer 2001;32:265-79.
    • (2001) Lung Cancer , vol.32 , pp. 265-279
    • Malkinson, A.K.1
  • 8
    • 1442303214 scopus 로고    scopus 로고
    • Molecular profiling of mouse lung tumors: Association with tumor progression, lung development and human lung adenocarcinoma
    • Bonner AE, Lemon WJ, Devereux TR, Lubet RA, You M. Molecular profiling of mouse lung tumors: association with tumor progression, lung development and human lung adenocarcinoma. Oncogene 2004;23:1166-76.
    • (2004) Oncogene , vol.23 , pp. 1166-1176
    • Bonner, A.E.1    Lemon, W.J.2    Devereux, T.R.3    Lubet, R.A.4    You, M.5
  • 11
    • 0034434321 scopus 로고    scopus 로고
    • Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli
    • Conaway CC, Getahun SM, Liebes LL, et al. Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli. Nutr Cancer 2000;38:168-78.
    • (2000) Nutr Cancer , vol.38 , pp. 168-178
    • Conaway, C.C.1    Getahun, S.M.2    Liebes, L.L.3
  • 12
    • 4143051307 scopus 로고    scopus 로고
    • Pharmacokinetics and tissue disposition of indole- 3-carbinol and its acid condensation products after oral administration to mice
    • Anderton MJ, Manson MM, Vershoyle RD, et al. Pharmacokinetics and tissue disposition of indole- 3-carbinol and its acid condensation products after oral administration to mice. Clin Cancer Res 2204; 10:5233-41.
    • (2204) Clin Cancer Res , vol.10 , pp. 5233-5241
    • Anderton, M.J.1    Manson, M.M.2    Vershoyle, R.D.3
  • 13
    • 0026046412 scopus 로고
    • Aromatic hydrocarbon receptor agonist generated from indole-3-carbinol in vitro and in vivo: Comparisons with 2,3,7,8-tetrachlorodibenzo- p-dioxin
    • Bjeldanes LF, Kim JY, Grose KR, Bartholomew JC, Bradfield CA. Aromatic hydrocarbon receptor agonist generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo- p-dioxin. Proc Natl Acad Sci U S A 1991;88: 9543-7.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 9543-9547
    • Bjeldanes, L.F.1    Kim, J.Y.2    Grose, K.R.3    Bartholomew, J.C.4    Bradfield, C.A.5
  • 14
    • 2942536030 scopus 로고    scopus 로고
    • Effects of cruciferous vegetable consumption on urinary metabolites of the tobacco-specificlung carcinogen 4-(methylnitrosamino)- 1-(3-pyridyl)-1- butanone in Singapore Chinese
    • Hecht SS, Carmella SG, Kenny PMJ, Low SH,Arakawa K, Yu MC. Effects of cruciferous vegetable consumption on urinary metabolites of the tobacco-specificlung carcinogen 4-(methylnitrosamino)- 1-(3-pyridyl)-1-butanone in Singapore Chinese. Cancer Epidemiol Biomarkers Prev 2004;13: 997-1004.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 997-1004
    • Hecht, S.S.1    Carmella, S.G.2    Kenny, P.M.J.3    Low, S.H.4    Arakawa, K.5    Yu, M.C.6
  • 15
    • 0031709151 scopus 로고
    • The chemistry and pharmacology of indole-3-carbinol (indole-3- methanol) and 3-(methoxymethyl)indole
    • Broadbent TA, Broadbent HS. The chemistry and pharmacology of indole-3-carbinol (indole-3- methanol) and 3-(methoxymethyl)indole. Curr Med Chem 1988;5:337-52.
    • (1988) Curr Med Chem , vol.5 , pp. 337-352
    • Broadbent, T.A.1    Broadbent, H.S.2
  • 16
    • 84985387077 scopus 로고
    • An estimate of the mean daily intake of glucosinolates from cruciferous vegetables in the UK
    • Sones K, Heaney RK, Fenwick GR. An estimate of the mean daily intake of glucosinolates from cruciferous vegetables in the UK. J Sci Food Agric 1984;35:712-20.
    • (1984) J Sci Food Agric , vol.35 , pp. 712-720
    • Sones, K.1    Heaney, R.K.2    Fenwick, G.R.3
  • 18
    • 0033842270 scopus 로고    scopus 로고
    • Placebo-controlled trial of indole-3-carbinol in the treatment of CN
    • Bell MC, Crowley-Nowick P, Bradlow HL, et al. Placebo-controlled trial of indole-3-carbinol in the treatment of CN. Gynecol Oncol 2000;78:123-9.
    • (2000) Gynecol Oncol , vol.78 , pp. 123-129
    • Bell, M.C.1    Crowley-Nowick, P.2    Bradlow, H.L.3
  • 19
    • 23844450586 scopus 로고    scopus 로고
    • A phase i study of indole-3-carbinol in women: Tolerability and effects
    • Reed GA, Peterson KS, Smith HJ, et al. A phase I study of indole-3-carbinol in women: tolerability and effects. Cancer Epidemiol Biomark Prev 2005;14:1953-60.
    • (2005) Cancer Epidemiol Biomark Prev , vol.14 , pp. 1953-1960
    • Reed, G.A.1    Peterson, K.S.2    Smith, H.J.3
  • 20
    • 0031894295 scopus 로고    scopus 로고
    • Indole-3-carbinol:anticarcinogen or tumor promoter in Brassica vegetables?
    • Dashwood RH. Indole-3-carbinol:anticarcinogen or tumor promoter in Brassica vegetables? Chem Biol Interact 1998;110:1-5.
    • (1998) Chem Biol Interact , vol.110 , pp. 1-5
    • Dashwood, R.H.1
  • 21
    • 34447133483 scopus 로고    scopus 로고
    • Indole-3-carbinol inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo(a)pyrene-induced lung tumorigenesis in A/J mice and modulates carcinogen-induced alterations in protein levels
    • Kassie F, Anderson LB, Scherber R, Yu N, Lahti D, Upadhyaya P, Hecht SS. Indole-3-carbinol inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo(a)pyrene-induced lung tumorigenesis in A/J mice and modulates carcinogen-induced alterations in protein levels. Cancer Res 2007;67: 6502-11.
    • (2007) Cancer Res , vol.67 , pp. 6502-6511
    • Kassie, F.1    Anderson, L.B.2    Scherber, R.3    Yu, N.4    Lahti, D.5    Upadhyaya, P.6    Hecht, S.S.7
  • 22
    • 0020954912 scopus 로고
    • Effects of α- Deuterium substitution on the mutagenicity of 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
    • Hecht SS, Lin D, Castonguay A. Effects of α- deuterium substitution on the mutagenicity of 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Carcinogenesis 1983;4:305-10.
    • (1983) Carcinogenesis , vol.4 , pp. 305-310
    • Hecht, S.S.1    Lin, D.2    Castonguay, A.3
  • 23
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves PG, Nielsen FH, Fahey GC. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993;123:1939-51.
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey, G.C.3
  • 24
    • 0036201862 scopus 로고    scopus 로고
    • Lung tumors in A/J mice exposed to environmental tobacco smoke: Estimated potency and implied human risk
    • Bogen KT, Witschi H. Lung tumors in A/J mice exposed to environmental tobacco smoke: estimated potency and implied human risk. Carcinogenesis 2002;23:511-19.
    • (2002) Carcinogenesis , vol.23 , pp. 511-519
    • Bogen, K.T.1    Witschi, H.2
  • 25
    • 0025818622 scopus 로고
    • Modifying responses of allyl sulfide, indole-3-carbinol and germanium in a rat multi-organ carcinogenesis model
    • Jang JJ, Cho KJ, Bae JH. Modifying responses of allyl sulfide, indole-3-carbinol and germanium in a rat multi-organ carcinogenesis model. Carcinogenesis 1991;12:691-95.
    • (1991) Carcinogenesis , vol.12 , pp. 691-695
    • Jang, J.J.1    Cho, K.J.2    Bae, J.H.3
  • 26
    • 35448962100 scopus 로고    scopus 로고
    • A phytoestrogen-rich diet increases energy expenditure and decreases adiposity in mice
    • Cederroth CR, Vinciguerra M, Kühne F, et al. A phytoestrogen-rich diet increases energy expenditure and decreases adiposity in mice. Environ Health Perspect 2007;115:1467-73.
    • (2007) Environ Health Perspect , vol.115 , pp. 1467-1473
    • Cederroth, C.R.1    Vinciguerra, M.2    Kühne, F.3
  • 27
    • 34948906392 scopus 로고    scopus 로고
    • Cruciferous indole-3-carbinol inhibits apolipoprotein B secretion in HeG2 cells
    • Maiyoh GK, Kuh JE, Casachi A, Theeiault AG. Cruciferous indole-3-carbinol inhibits apolipoprotein B secretion in HeG2 cells. J Nutr 2007;137: 2185-89.
    • (2007) J Nutr , vol.137 , pp. 2185-2189
    • Maiyoh, G.K.1    Kuh, J.E.2    Casachi, A.3    Theeiault, A.G.4
  • 28
    • 40949106397 scopus 로고    scopus 로고
    • Chemopreventive agents modulate the protein expression profile of 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone plus benzo(a)pyrene-induced lung tumors in A/J mice
    • Kassie F, Anderson LB, Higgins L, et al. Chemopreventive agents modulate the protein expression profile of 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone plus benzo(a)pyrene-induced lung tumors in A/J mice. Carcinogenesis 2008;29: 610-19.
    • (2008) Carcinogenesis , vol.29 , pp. 610-619
    • Kassie, F.1    Anderson, L.B.2    Higgins, L.3
  • 29
    • 0013072999 scopus 로고    scopus 로고
    • Calorie restriction, aging, and cancer prevention: Mechanisms of action and applicability to humans
    • Hursting SD, Lavigne JA, Berrigan D, Perkins SN, Barrett JC. Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. Annu Rev Med 2003;54:131-52.
    • (2003) Annu Rev Med , vol.54 , pp. 131-152
    • Hursting, S.D.1    Lavigne, J.A.2    Berrigan, D.3    Perkins, S.N.4    Barrett, J.C.5
  • 30
    • 17644411418 scopus 로고    scopus 로고
    • Mechanisms involved in A/J mouse lung tumorigenesis induced by inhalation of an environmental tobacco smoke surrogate
    • Stinn W, Teredesai A, Kuhl P, Knoerr-Wittmann C, Kindt R. Mechanisms involved in A/J mouse lung tumorigenesis induced by inhalation of an environmental tobacco smoke surrogate. Inhal Toxicol 2005;17:263-76.
    • (2005) Inhal Toxicol , vol.17 , pp. 263-276
    • Stinn, W.1    Teredesai, A.2    Kuhl, P.3    Knoerr-Wittmann, C.4    Kindt, R.5
  • 31
    • 0025317426 scopus 로고
    • Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)- 1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice
    • Morse MA, LaGreca SD, Amin SG, Chung FL. Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)- 1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice. Cancer Res 1990;50:2613-17.
    • (1990) Cancer Res , vol.50 , pp. 2613-2617
    • Morse, M.A.1    Lagreca, S.D.2    Amin, S.G.3    Chung, F.L.4
  • 32
    • 0029909080 scopus 로고    scopus 로고
    • Effects of 1,4-phenylenebis (methylene)selenocyanate, phenethyl isothiocyanate, indole-3-carbinol, and ≻d-limonene individually and in combination on the tumorigenicity of the tobacco-specific nitrosamine 4-(methylnitrosamino)- 1-(3-pyridyl)-1-butanone in A/J mouse lung
    • El Bayoumy K, Upadhyaya P, Desai DH, Amin S, Hoffmann D, Wynder EL. Effects of 1,4-phenylenebis (methylene)selenocyanate, phenethyl isothiocyanate, indole-3-carbinol, and ≻d-limonene individually and in combination on the tumorigenicity of the tobacco-specific nitrosamine 4-(methylnitrosamino)- 1-(3-pyridyl)-1-butanone in A/J mouse lung. Anticancer Res 1996;16:2709-12.
    • (1996) Anticancer Res , vol.16 , pp. 2709-2712
    • El Bayoumy, K.1    Upadhyaya, P.2    Desai, D.H.3    Amin, S.4    Hoffmann, D.5    Wynder, E.L.6
  • 33
    • 33749576079 scopus 로고    scopus 로고
    • Indole-3- carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the polycyclic aromatic hydrocarbon dibenzo[a,l]pyrene
    • Yu Z, Mahadevan B, Löhr CV, et al. Indole-3- carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the polycyclic aromatic hydrocarbon dibenzo[a,l]pyrene. Carcinogenesis 2006;27:2116-23.
    • (2006) Carcinogenesis , vol.27 , pp. 2116-2123
    • Yu, Z.1    Mahadevan, B.2    Löhr, C.V.3
  • 34
    • 34548029142 scopus 로고    scopus 로고
    • Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice
    • Weng Y, Fang C, Turesky RJ, Behr M, Kaminsky LS, Ding X. Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice. Cancer Res 2007;67:7825-30.
    • (2007) Cancer Res , vol.67 , pp. 7825-7830
    • Weng, Y.1    Fang, C.2    Turesky, R.J.3    Behr, M.4    Kaminsky, L.S.5    Ding, X.6
  • 35
    • 40949083424 scopus 로고    scopus 로고
    • Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: Experiments with hepatic cytochrome P450 reductase null mice
    • Arlt VM, Stiborová M, Henderson CJ, et al. Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice. Carcinogenesis 2008; 29:656-65.
    • (2008) Carcinogenesis , vol.29 , pp. 656-665
    • Arlt, V.M.1    Stiborová, M.2    Henderson, C.J.3
  • 36
    • 0016803938 scopus 로고
    • Aryl hydrocarbon hydroxylase induction in rat tissues by naturally occurring indoles of cruciferous plants
    • Loub WD, Wattenberg LW, Davis DW. Aryl hydrocarbon hydroxylase induction in rat tissues by naturally occurring indoles of cruciferous plants. J Natl Cancer Inst 1975;54:985-8.
    • (1975) J Natl Cancer Inst , vol.54 , pp. 985-988
    • Loub, W.D.1    Wattenberg, L.W.2    Davis, D.W.3
  • 37
    • 0026731082 scopus 로고
    • Organ-selective induction of cytochrome P-450-dependent activities by indole- 3-carbinol-derived products: Influence on covalent binding of benzo[a]pyrene to hepatic and pulmonary DNA in the rat
    • Park JY, Bjeldanes LF. Organ-selective induction of cytochrome P-450-dependent activities by indole- 3-carbinol-derived products: influence on covalent binding of benzo[a]pyrene to hepatic and pulmonary DNA in the rat. Chem Biol Intract 1992; 83:235-47.
    • (1992) Chem Biol Intract , vol.83 , pp. 235-247
    • Park, J.Y.1    Bjeldanes, L.F.2
  • 38
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cellintrinsic death machinery
    • Datta SR, Dudek H, Tao X, et al. Akt phosphorylation of BAD couples survival signals to the cellintrinsic death machinery. Cell 1997;91:231-41.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3
  • 39
    • 0035208658 scopus 로고    scopus 로고
    • Indole-3- carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16- transgenic preneoplastic cervical epithelium
    • Chen DZ, Qi M, Auborn KJ, Carter TH. Indole-3- carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16- transgenic preneoplastic cervical epithelium. J Nutr 2001;131:3294-302.
    • (2001) J Nutr , vol.131 , pp. 3294-3302
    • Chen, D.Z.1    Qi, M.2    Auborn, K.J.3    Carter, T.H.4
  • 40
    • 0033567096 scopus 로고    scopus 로고
    • Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice
    • Jin L, Qi M, Chen DZ, Anderson A, Yang GY, Arbeit JM, Auborn KJ. Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice. Cancer Res 1999;59: 3991-97.
    • (1999) Cancer Res , vol.59 , pp. 3991-3997
    • Jin, L.1    Qi, M.2    Chen, D.Z.3    Anderson, A.4    Yang, G.Y.5    Arbeit, J.M.6    Auborn, K.J.7
  • 41
    • 38649100664 scopus 로고    scopus 로고
    • Indole-3-carbinol (I3C) exhibits inhibitory and preventive effects on prostate tumors in mice
    • Souli E, Machluf M, Morgenstem A, Sabo E,Yannai S. Indole-3-carbinol (I3C) exhibits inhibitory and preventive effects on prostate tumors in mice. Food Chem Toxicol 2008;46:863-70.
    • (2008) Food Chem Toxicol , vol.46 , pp. 863-870
    • Souli, E.1    MacHluf, M.2    Morgenstem, A.3    Sabo Eyannai, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.