A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines

Cancer Research

Volumn 63, Issue 14, 2003, Pages 4028-4036

  Brandi, Giorgio ^a   Paiardini, Mirko ^a   Cervasi, Barbara ^a   Fiorucci, Chiara ^a   Filippone, Paolino ^a   De Marco, Cinzia ^b   Zaffaroni, Nadia ^b   Magnani, Mauro ^a  

^a UNIVERSITY OF URBINO   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 INDOLEMETHANOL; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; ESTROGEN RECEPTOR; GLUCOSINOLATE; POLYMER; PROTEIN P27; RETINOBLASTOMA PROTEIN; TETRAMER;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOLYSIS; BREAST CANCER; CANCER CELL CULTURE; CELL CYCLE G1 PHASE; CELL VIABILITY; CYTOSTASIS; ENZYME INHIBITION; ESTROGEN METABOLISM; GROWTH INHIBITION; HORMONE DEPENDENCE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; TUMOR GROWTH;

APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; ENZYME INDUCTION; ENZYME INHIBITORS; ESTROGEN RECEPTOR MODULATORS; G1 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INDOLES; NEOPLASMS, HORMONE-DEPENDENT; PHOSPHORYLATION; RECEPTORS, ESTROGEN; RETINOBLASTOMA PROTEIN; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 0042173140     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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