Epigallocatechin-3-gallate decreases VEGF production in head and neck and breast carcinoma cells by inhibiting EGFR-related pathways of signal transduction

Journal of Experimental Therapeutics and Oncology

Volumn 2, Issue 6, 2002, Pages 350-359

  Masuda, Muneyuki ^a   Suzui, Masumi ^a   Lim, Jin T E ^a   Deguchi, Atsuko ^a   Soh, Jae Won ^a   Weinstein, I Bernard ^a  

^a Columbia University ^*  (United States)

Author keywords

Angiogenesis; EGCG; NF B; PI3K Akt; Stat3; VEGF

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIGALLOCATECHIN GALLATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA; VASCULOTROPIN; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ANTINEOPLASTIC AGENT; CATECHIN; CHROMONE DERIVATIVE; DNA BINDING PROTEIN; DRUG DERIVATIVE; ENDOTHELIAL CELL GROWTH FACTOR; ENZYME INHIBITOR; FLAVONOID; LUCIFERASE; LYMPHOKINE; MAP3K1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; MORPHOLINE DERIVATIVE; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; STAT3 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; UROKINASE; VASCULOTROPIN A;

ANGIOGENESIS; ARTICLE; AUTOCRINE EFFECT; BREAST CARCINOMA; CARCINOMA CELL; CELL LINE; ENZYME LINKED IMMUNOSORBENT ASSAY; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; TEA; BIOLOGICAL MODEL; BIOSYNTHESIS; BREAST TUMOR; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HEAD AND NECK TUMOR; METABOLISM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CARCINOMA, SQUAMOUS CELL; CATECHIN; CHROMONES; DNA-BINDING PROTEINS; ENDOTHELIAL GROWTH FACTORS; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; LYMPHOKINES; MAP KINASE KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MORPHOLINES; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR CELLS, CULTURED; URINARY PLASMINOGEN ACTIVATOR; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0036842094     PISSN: 13594117     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1359-4117.2002.01062.x     Document Type: Article

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