Differential effects of lycopene consumed in tomato paste and lycopene in the form of a purified extract on target genes of cancer prostatic cells

American Journal of Clinical Nutrition

Volumn 91, Issue 6, 2010, Pages 1716-1724

  Talvas, Jérémie ^a   Caris Veyrat, Catherine ^b   Guy, Laurent ^c   Rambeau, Mathieu ^a   Lyan, Bernard ^a   Minet Quinard, Régine ^c   Lobaccaro, Jean Marc Adolphe ^d   Vasson, Marie Paule ^d   Georgé, Stéphane ^e   Mazur, Andrzej ^a   Rock, Edmond ^a  

^a INRA and University of Auvergne   (France)

^b Quality and Security of Plant Products   (France)

^c University of Clermont Ferrand   (France)

^d UNIVERSITÉ CLERMONT AUVERGNE   (France)

^e Nutrition Department   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BETA CAROTENE; CAROTENOID; CHOLESTEROL; CYCLIN D1; LIPID; LYCOPENE; PLACEBO; PROSTATE SPECIFIC ANTIGEN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN C FOS; PROTEIN P53; RETINOL; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; TRANSCRIPTION FACTOR NRF2; TRIACYLGLYCEROL; XANTHOPHYLL; ZEAXANTHIN;

ADULT; AGED; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER PREVENTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DOWN REGULATION; DRUG BLOOD LEVEL; FOOD INTAKE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LYMPH NODE; LYMPHOMA; MALE; NORMAL HUMAN; PROSTATE CANCER; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; TOMATO; UPREGULATION;

AGED; BCL-2-ASSOCIATED X PROTEIN; CAROTENOIDS; CELL LINE, TUMOR; CHOLESTEROL; CROSS-OVER STUDIES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; LYCOPERSICON ESCULENTUM; MALE; MIDDLE AGED; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRIGLYCERIDES;

LYCOPERSICON ESCULENTUM;

EID: 77953047006     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.2009.28666     Document Type: Article

References (46)

1. Kavanaugh CJ, Trumbo PR, Ellwood KC. The U.S. Food and Drug Administration's evidence-based review for qualified health claims: tomatoes, lycopene, and cancer. J Natl Cancer Inst 2007;99:1074-1085
2. WCRF/AICR. Food, nutrition, physical activity, and the prevention of cancer: a global perspective. Washington, DC: World Cancer Research Fund/American Institute for Cancer Research, 2007.
3. Mills PK, Beeson WL, Phillips RL, Fraser GE. Cohort study of diet, lifestyle, and prostate cancer in Adventist men. Cancer 1989;64:598-604.
4. Giovannucci E. A review of epidemiologic studies of tomatoes, lycopene, and prostate cancer. Exp Biol Med (Maywood) 2002;227:852-859
5. Di Mascio P, Kaiser S, Sies H. Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch Biochem Biophys 1989;274:532-538
6. Clinton SK, Emenhiser C, Schwartz SJ, et al. cis-trans Lycopene isomers, carotenoids, and retinol in the human prostate. Cancer Epidemiol Biomarkers Prev 1996;5:823-833 (Pubitemid 26346282)
7. Ames BN. Dietary carcinogens and anticarcinogens: oxygen radicals and degenerative diseases. Science 1983;221:1256-1264
8. van Breemen RB, Pajkovic N. Multitargeted therapy of cancer by lycopene. Cancer Lett 2008;269:339-351
9. Erdman JW Jr, Ford NA, Lindshield BL. Are the health attributes of lycopene related to its antioxidant function? Arch Biochem Biophys 2008;483:229-235
10. Siler U, Herzog A, Spitzer V, et al. Lycopene effects on rat normal prostate and prostate tumor tissue. J Nutr 2005;135:2050S-2S.
11. Boileau TW, Liao Z, Kim S, Lemeshow S, Erdman JW Jr, Clinton SK. Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. J Natl Cancer Inst 2003;95:1578-1586 (Pubitemid 37455925)
12. Kucuk O, Sarkar FH, Sakr W, et al. Phase II randomized clinical trial of lycopene supplementation before radical prostatectomy. Cancer Epidemiol Biomarkers Prev 2001;10:861-868
13. Chen L, Stacewicz-Sapuntzakis M, Duncan C, et al. Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention. J Natl Cancer Inst 2001;93:1872-1879 (Pubitemid 34048654)
14. Clark PE, Hall MC, Borden LS Jr, et al. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse of prostate cancer after definitive local therapy. Urology 2006;67:1257-1261
15. Jatoi A, Burch P, Hillman D, et al. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a phase II study from the North Central Cancer Treatment Group. Urology 2007;69:289-294
16. Gann PH, Khachik F. Tomatoes or lycopene versus prostate cancer: is evolution anti-reductionist? J Natl Cancer Inst 2003;95:1563-1565
17. Gitenay D, Lyan B, Talvas J, et al. Serum from rats fed red or yellow tomatoes induces connexin43 expression independently from lycopene in a prostate cancer cell line. Biochem Biophys Res Commun 2007;364:578-582 (Pubitemid 350030922)
18. Gitenay D, Lyan B, Rambeau M, Mazur A, Rock E. Comparison of lycopene and tomato effects on biomarkers of oxidative stress in vitamin E deficient rats. Eur J Nutr 2007;46:468-475 (Pubitemid 50004079)
19. Lyan B, Azais-Braesco V, Cardinault N, et al. Simple method for clinical determination of 13 carotenoids in human plasma using an isocratic high-performance liquid chromatographic method. J Chromatogr B Biomed Sci Appl 2001;751:297-303. (Pubitemid 32126317)
20. Tessier F, Birlouez-Aragon I, Tjani C, Guilland JC. Validation of a micromethod for determining oxidized and reduced vitamin C in plasma by HPLC-fluorescence. Int J Vitam Nutr Res 1996;66:166-170 (Pubitemid 26263559)
21. Benzie IF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. Anal Biochem 1996;239:70-76
22. Vandesompele J, De Preter K, Pattyn F, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002;3:r34.1-11.
23. Talvas J, Obled A, Fafournoux P, Mordier S. Regulation of protein synthesis by leucine starvation involves distinct mechanisms in mouse C2C12 myoblasts and myotubes. J Nutr 2006;136:1466-1471
24. Porrini M, Riso P, Brusamolino A, Berti C, Guarnieri S, Visioli F. Daily intake of a formulated tomato drink affects carotenoid plasma and lymphocyte concentrations and improves cellular antioxidant protection. Br J Nutr 2005;93:93-99
25. Mucci LA, Tamimi R, Lagiou P, et al. Are dietary influences on the risk of prostate cancer mediated through the insulin-like growth factor system? BJU Int 2001;87:814-820
26. Edinger MS, Koff WJ. Effect of the consumption of tomato paste on plasma prostate-specific antigen levels in patients with benign prostate hyperplasia. Braz J Med Biol Res 2006;39:1115-1119
27. Afman L, Muller M. Nutrigenomics: from molecular nutrition to prevention of disease. J Am Diet Assoc 2006;106:569-576
28. Yamada PM, Lee KW. Perspectives in mammalian IGFBP-3 biology: local vs. systemic action. Am J Physiol Cell Physiol 2009;296:C954-76.
29. Kruse JP, Gu W. Modes of p53 regulation. Cell 2009;137:609-622
30. Kensler TW, Wakabayashi N, Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol 2007;47:89-116.
31. Liu C, Lian F, Smith DE, Russell RM, Wang XD. Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets. Cancer Res 2003;63:3138-3144
32. Kanagaraj P, Vijayababu MR, Ravisankar B, Anbalagan J, Aruldhas MM, Arunakaran J. Effect of lycopene on insulin-like growth factor-I, IGF binding protein-3 and IGF type-I receptor in prostate cancer cells. J Cancer Res Clin Oncol 2007;133:351-359 (Pubitemid 46716699)
33. Rajah R, Valentinis B, Cohen P. Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism. J Biol Chem 1997;272:12181-12188 (Pubitemid 27202802)
34. Rajah R, Lee KW, Cohen P. Insulin-like growth factor binding protein-3 mediates tumor necrosis factor-alpha-induced apoptosis: role of Bcl-2 phosphorylation. Cell Growth Differ 2002;13:163-171 (Pubitemid 34507095)
35. Wang A, Zhang L. [Effect of lycopene on proliferation and cell cycle of hormone refractory prostate cancer PC-3 cell line]. Wei Sheng Yan Jiu 2007;36:575-578 (in Chinese).
36. Velmurugan B, Mani A, Nagini S. Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl-2, Bax, Bim and caspases during experimental gastric carcinogenesis. Eur J Cancer Prev 2005;14:387-393 (Pubitemid 41104948)
37. Venkateswaran V, Klotz LH, Ramani M, et al. A combination of micronutrients is beneficial in reducing the incidence of prostate cancer and increasing survival in the Lady transgenic model. Cancer Prev Res (Phila Pa) 2009;2:473-483
38. Peng L, Wang J, Malloy PJ, Feldman D. The role of insulin-like growth factor binding protein-3 in the growth inhibitory actions of androgens in LNCaP human prostate cancer cells. Int J Cancer 2008;122:558-566
39. Shukla S, Mishra A, Fu P, MacLennan GT, Resnick MI, Gupta S. Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice. FASEB J 2005;19:2042-2044
40. Nahum A, Zeller L, Danilenko M, et al. Lycopene inhibition of IGF-induced cancer cell growth depends on the level of cyclin D1. Eur J Nutr 2006;45:275-282
41. Ivanov NI, Cowell SP, Brown P, Rennie PS, Guns ES, Cox ME. Lycopene differentially induces quiescence and apoptosis in androgenresponsive and -independent prostate cancer cell lines. Clin Nutr 2007;26:252-263
42. Tang FY, Shih CJ, Cheng LH, Ho HJ, Chen HJ. Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway. Mol Nutr Food Res 2008;52:646-654
43. Cheng HC, Chien H, Liao CH, Yang YY, Huang SY. Carotenoids suppress proliferating cell nuclear antigen and cyclin D1 expression in oral carcinogenic models. J Nutr Biochem 2007;18:667-675 (Pubitemid 47386030)
44. Obermuller-Jevic UC, Olano-Martin E, Corbacho AM, et al. Lycopene inhibits the growth of normal human prostate epithelial cells in vitro. J Nutr 2003;133:3356-3360 (Pubitemid 37409459)
45. Forbes K, Gillette K, Sehgal I. Lycopene increases urokinase receptor and fails to inhibit growth or connexin expression in a metastatically passaged prostate cancer cell line: a brief communication. Exp Biol Med (Maywood) 2003;228:967-971
46. Milde-Langosch K. The Fos family of transcription factors and their role in tumourigenesis. Eur J Cancer 2005;41:2449-2461 (Pubitemid 41540622)