Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis

Carcinogenesis

Volumn 18, Issue 1, 1997, Pages 83-88

  Huang, Mou Tuan ^a   Ma, Wei ^a   Yen, Patricia ^a   Xie, Jian Guo ^a   Han, Jingkang ^b   Frenkel, Krystyna ^b   Grunberger, Dezider ^c   Conney, Allan H ^a  

^a RUTGERS UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c The New York Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLDEOXYURIDINE; 7,12 DIMETHYLBENZ[A]ANTHRACENE; CURCUMIN; PHORBOL 13 ACETATE 12 MYRISTATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DNA MODIFICATION; DNA SYNTHESIS INHIBITION; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA SYNTHESIS; SKIN CARCINOGENESIS; TOPICAL DRUG ADMINISTRATION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ADMINISTRATION, TOPICAL; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOGENS; CURCUMIN; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HELA CELLS; HUMANS; MICE; NEOPLASMS, EXPERIMENTAL; OXIDATION-REDUCTION; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE;

EID: 0031418195     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/18.1.83     Document Type: Article

References (48)

1. Chopra,R.N., Chopra,I.C., Handa,K.L. and Kapur,L.D. (1958) In Indigenous Drugs of India, 2nd Edn. Dhur, Calcutta, pp. 325-327.
2. Nadkarn,K.M. (1976) Curcuma longa. In Nadkarni,K.M. (ed.) India Materia Medica. Popular Prakashan Publishing Co., Bombay, pp. 414-416.
3. Bacon,E. (1979) Health protection branch regulation of food additives. Can. Pharm. J., 112, 340-344.
4. Marmion,D.M. (1979) Colorants exempt from certification. In Handbook of U.S. Colorants for Food, Drugs and Cosmetics. John Wiley & Sons, New York, pp. 86-87.
5. Govindarajan,V.S. (1980) Turmeric chemistry, technology and quality. CRC Rev. Food Sci. Nutr., 12, 199-301.
6. Flynn,D.L., Rafferty,M.F. and Boctor,A.M. (1986) Inhibition of 5-hydroxyeicosatetraenoic acid (5-HETE) formation in intact human neutrophils by naturally occurring diarylheptanoids: inhibitory activities of curcuminoids and yakuchinones. Leukotrienes Med., 22, 357-360.
7. Huang,M.-T., Lysz,T., Ferraro,T., Abidi.T.F., Laskin,J.D. and Conney,A.H. (1991) Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res., 51, 813-819.
8. Rao,C., Rivenson,R.A., Simi,B. and Reddy,B.S. (1995) Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compounds. Cancer Res., 55, 259-266.
9. Sharma,O.P. (1976) Antioxidant activity of curcumin and related compounds. Biochem. Pharmacol., 25, 1811-1812.
10. Toda,S., Miyase,T., Arichi,H., Tanizawa,H. and Takino,Y. (1985) Natural antioxidant. III. Antioxidative components isolated from rhizome of Curcuma longa L. Chem. Pharmaceut. Bull. (Tokyo), 33, 1725-1728.
11. Srimal,R.C. and Dhawan,B.N. (1973) Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J. Pharm. Pharmacol., 25, 447-452.
12. Rao,T.S., Basu,N. and Siddiqui,H.H. (1982) Anti-inflammatory activity of curcumin analogues. Indian J. Med. Res., 75, 574-578.
13. MukhopadhyayA., Basu,N., Ghatak,N. and Gujral,P.K. (1982) Anti-inflammatory and irritant activities of curcumin analogues in rats. Agents Actions, 12, 508-512.
14. Ammon,H.P.T, and Wahl,M.A. (1991) Pharmacology of curcuma longa. Planta Med., 57, 1-7.
15. Huang,M.-T., Robertson,F.M,. Lysz,T., Ferraro,T., Wang,Z.Y., Georgiadis,C.A., Laskin,J.D. and Conney,A.H. (1992) Inhibitory effects of curcumin on carcinogenesis in mouse epidermis. In Huang,M.-T., Ho,C.-T. and Lee,C.Y. (eds) Phenolic Compounds in Food and Their Effects on Health II: Antioxidants and Cancer Prevention, Vol. 2. American Chemical Society Symposium 507, Washington, DC, pp. 338-349.
16. Tonnesen,H.H. (1992) Chemistry of curcumin and curcuminoids. In Ho,C-T., Lee,C.Y. and Huang,M.-T. (eds) Phenolic Compounds in Foods and Their Effects on Health, Vol. 1: Analysis, Occurrence and Chemistry. American Chemical Society, Washington, DC, ACS Symposium Series No. 506, pp. 143-153.
17. Huang,M.-T., Smart,R.C., Wong,C-Q. and Conney,A.H. (1988) Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoytphorbol-13-acetate. Cancer Res., 48, 5941-5946.
18. Lu,Y.-P., Chang,R.L., Huang,M-T. and Conney,A.H. (1993) Inhibitory effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced increase in ornithine decarboxylase mRNA in mouse epidermis. Carcinogenesis, 14, 293-297.
19. Lu,Y.-P., Chang,R.L., Lou,Y-R., Huang,M-T., Newmark,H.L., Reuhl,K.R. and Conney,A.H. (1994) Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate- and ultraviolet B light-induced expression of c-Jun and c-Fos in JB6 cells and in mouse epidermis. Carcinogenesis, 15, 2363-2370.
20. Huang,M.-T., Ma,W., Lou,Y-R., Lu,Y-P., Chang,R., Newmark,H. and Conney,A.H. (In press, 1996) Inhibitory effects of curcumin on tumorigenesis in mice. International Symposium on Curcumin Pharmacochemistry, 29-30 August, 1995 at Gadjah Mada University, Yogyakarta, Indonesia.
21. Wei,H. and Frenkel,K. (1991) In vivo formation of oxidized DNA bases in tumor promoter-treated mouse skin. Cancer Res., 51, 4443-4449.
22. Matsuda,T.A., Shinozaki,M., Suzuki,M., Watanabe,K. and Miyasaka,T. (1986) Convenient method for the selective acylation of guanine nucleosides. Synthesis, 12, 385-386.
23. Frenkel,K., Zhang,Z., Wei,H., Karkoszka,J., Patel,U., Rashid,K., Georgescu,M. and Solomon,J.J. (1991) Quantitative high-performance liquid chromatography analysis of DNA oxidized in vitro and in vitro. Anal. Biochem., 196, 126-136.
24. Huang,M.-T. (1975) Harringtonine, an inhibitor of initiation of protein biosynthesis. Mol. Pharmacol., 11, 511-519.
25. Robertson,F.M., Beavis,A.J., Oberyszyn,T.M., O'Connell,S.M., Dokidos,A., Laskin,D.L., Laskin,J.D. and Reiners,J.J. (1990) Production of hydrogen peroxide by murine epidermal keratinocytes following treatment with the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate. Cancer Res., 50, 6062-6067.
26. Keston,A.S. and Brandt,R. (1965) The fluorornetric analysis of ultramicro quantities of hydrogen peroxide. Anal. Biochem., 11, 1-5.
27. Bass,D.A., Parce,J.W., Dechatelet,L.R., Szeja,P., Seeds,M.C. and Thomas,M. (1983) Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. J. Immunol., 130, 1910-1917.
28. Wei,H. and Frenkel,K. (1993) Relationship of oxidative events and DNA oxidation in SENCAR mice to in vivo promoting activity of phorbol ester-type tumor promoters. Carcinogenesis, 14, 1195-1201.
29. Frenkel,K., Wei,H., Bhimani,R., Ye,J., Zadunaisky,J.A., Huang,M.-T., Ferraro,T., Conney,A.H. and Grunberger,D. (1993) Inhibition of tumor promotor-mediated processes in mouse skin and bovine lens by caffeic acid phenetbyl ester. Cancer Res., 53, 1255-1261.
30. Kakar,S.S. and Roy,D. (1994) Curcumin inhibits TPA-induced expression of c-fos, c-jun, and c-myc protooncogene messenger RNAs in mouse skin. Cancer Lett., 87, 85-89.
31. Armstad,PA., Krupitza,G. and Cerutti,P. (1992) Mechanism of c-fos induction by active oxygen. Cancer Res., 52, 3952-3960.
32. Rao,G.N., Lassegue,B., Griendling,K.K., Alexander,R.W., Berk,B.C. (1993) Hydrogen peroxide-induced c-fos expression is mediated by arachidonic acid release: Role for protein kinase C. Nucleic Acid Res., 21, 1259-1263.
33. Datta,R., Hallahan,D.E., Kharbanda,S.M., Rubin,E., Shennan,K.M., Humberman,E., Weichselbaurm,R.R. and Kufe,D.W. (1992) Involvement of reactive oxygen intermediates in the induction of c-jun gene transcription by ionising radiation. Biochemistry, 31, 8300-8306.
34. Kelley,D.J., Sacks,P.G., Ramonetti,J.T., Schantz,S.P., Dannenberg,A.J. (1996) Curcumin inhibits prostaglandin synthesis and cyclooxygenase-2 expression in oral epithelial cells. Proc. Amer. Assoc. Cancer Res., 37, 598.
35. Chan,M.M.-Y, Ho,C.-T., Huang,H.-I. (1995) Effects of three dietary phytochemicals from tea, rosemary and turmeric on inflammation-induced nitrite production. Cancer Lett., 96, 23-29.
36. Chan,M.M.-Y. (1995) Inhibition of tumor necrosis factor by curcumin, a phytochemical. Biochem. Pharmacol., 49, 1551-1556.
37. Jiang,M.-C., Yang-Yen,H.-F., Yen,J.J.-Y., and Lin,J.-K. (1996) Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines. Nutr. Cancer., 26, 111-120.
38. Huang,M-T., Wang,Z.Y., Georgiadis,C.A., Laskin,J.D. and Conney,A.H. (1992) Inhibitory effect of curcumin on tumor initiation by benzo[a]pyrene and 7,12-dimethylbenz[a] anthracene. Carcinogenesis (Lond.), 13, 947-954.
39. Huang,M.-T., Lou,Y.-R., Ma,W., Newmark,H.L., Reuhl,K.R. and Conney,A.H. (1994) Inhibitory effects of dietary curcumin on forestomach, duodenal and colon carcinogenesis in mice. Cancer Res., 54, 5841-5847.
40. Tanaka,T., Makita,H., Ohnishi,M., Hirose,Y., Wang,A., Mori,H., Satoh,K., Hara,A. and Ogawa,H. (1994) Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: comparison with the protective effect of β-carotene. Cancer Res., 54, 4653-4659.
41. Huang,M.-T., Ma,W., Lu,Y-R, Chang,R.L., Fisher,C., Manchand,P.S., Newmark,H.L. and Conney,A.H. (1995) Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin, and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion. Carcinogenesis, 16, 2493-2497.
42. Huang,M.-T., Ma,W., Yen,P., Xie,J.-G., Han,J., Frenkel,K., Grunberger,D. and Conney,A.H. (1996) Inhibitory effects of caffeic acid phenethyl ester (CAPE) on 12-O-tetradecanoylphorbol-13-acetate-induced rumor promotion in mouse skin and the synthesis of DNA, RNA and protein in HeLa cells. Carcinogenesis, 17, 761-765.
43. Li,C.J., Zhang,L.J., Dezube,B.J., Crumpacker.C.S, and Pardee,A.B. (1993) Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication, Proc. Natl Acad. Sci. USA, 90, 1839-1842.
44. Menon,L.G., Kuttan,R. and Kuttan,G. (1995) Inhibition of lung metastasis in mice induced by B16F10 melanoma cells by polyphenolic compounds. Cancer Lett., 95, 221-225.
45. Nagabhushan,M., Ushe,K., Rangnekar,V.M. and Ranjan,D. (1996) Curcumin is cytotoxic to cancer cells. Proc. Amer. Assoc. Cancer Res., 37, 409.
46. Avis,I.M., Jett,M., Boyle,T., Vos,M.D., Moody,T., Treston,A.M., Martinez,A. and Mulshine,J.L. (1996) Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling. J. Clin. Invest., 97, 806-813.
47. Tsukada,T., Nakashima,K. and Shirakawa,S. (1986) Arachidonic 5-lipoxygenase inhibitors show potent antiproliferative effects on human leukemic cell lines. Biochem. Biophys. Res. Commun., 140, 812-816.
48. 4. Cancer Res., 49, 1138-1142.