-
1
-
-
0031985198
-
Multiple myeloma: Increasing evidence for a multistep transformation process
-
Hallek, M., P. L. Bergsagel, and K. C. Anderson. 1998. Multiple myeloma: increasing evidence for a multistep transformation process. Blood 91:3.
-
(1998)
Blood
, vol.91
, pp. 3
-
-
Hallek, M.1
Bergsagel, P.L.2
Anderson, K.C.3
-
2
-
-
0035675491
-
Diagnosis and management of multiple myeloma
-
UK myeloma forum. British Committee for Standards in Haemotology. 2001. Diagnosis and management of multiple myeloma. Br. J. Haematol. 115:522.
-
(2001)
Br. J. Haematol.
, vol.115
, pp. 522
-
-
-
3
-
-
85039627481
-
Report
-
National Cancer Institute, Bethesda
-
Anonymous. 1992. Report. In 1973-1989 Annual Cancer Statistics Review. National Cancer Institute, Bethesda.
-
(1992)
1973-1989 Annual Cancer Statistics Review
-
-
-
4
-
-
0033121314
-
Role of NF-κB in the rescue of multiple myeloma cells from glucocorticoid-induced apoptosis by bcl-2
-
Feinman, R., J. Koury, M. Thames, B. Barlogie, J. Epstein, and D. S. Siegel. 1999. Role of NF-κB in the rescue of multiple myeloma cells from glucocorticoid-induced apoptosis by bcl-2. Blood 93:3044.
-
(1999)
Blood
, vol.93
, pp. 3044
-
-
Feinman, R.1
Koury, J.2
Thames, M.3
Barlogie, B.4
Epstein, J.5
Siegel, D.S.6
-
5
-
-
0023849455
-
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
-
Kawano, M., T. Hirano, T. Matsuda, T. Taga, Y. Horii, K. Iwato, H. Asaoku, B. Tang, O. Tanabe, H. Tanaka, et al. 1988. Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas. Nature 332:83.
-
(1988)
Nature
, vol.332
, pp. 83
-
-
Kawano, M.1
Hirano, T.2
Matsuda, T.3
Taga, T.4
Horii, Y.5
Iwato, K.6
Asaoku, H.7
Tang, B.8
Tanabe, O.9
Tanaka, H.10
-
6
-
-
0028921477
-
Interleukin-6 in human multiple myeloma
-
Klein, B., X. G. Zhang, Z. Y. Lu, and R. Bataille. 1995. Interleukin-6 in human multiple myeloma. Blood 85:863.
-
(1995)
Blood
, vol.85
, pp. 863
-
-
Klein, B.1
Zhang, X.G.2
Lu, Z.Y.3
Bataille, R.4
-
7
-
-
0030840464
-
STATs and gene regulation
-
Darnell, J. E., Jr. 1997. STATs and gene regulation. Science 277:1630.
-
(1997)
Science
, vol.277
, pp. 1630
-
-
Darnell J.E., Jr.1
-
8
-
-
0030890718
-
Gp130 and the interleukin-6 family of cytokines
-
Taga, T., and T. Kishimoto. 1997. Gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol. 15:797.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 797
-
-
Taga, T.1
Kishimoto, T.2
-
9
-
-
0031893214
-
Stat3 activation is required for cellular transformation by v-src
-
Bromberg, J. F., C. M. Horvath, D. Besser, W. W. Lathem, and J. E. Darnell, Jr. 1998. Stat3 activation is required for cellular transformation by v-src. Mol. Cell Biol. 18:2553.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 2553
-
-
Bromberg, J.F.1
Horvath, C.M.2
Besser, D.3
Lathem, W.W.4
Darnell J.E., Jr.5
-
10
-
-
0031953831
-
Stat3 activation by Src induces specific gene regulation and is required for cell transformation
-
Turkson, J., T. Bowman, R. Garcia, E. Caldenhoven, R. P. De Groot, and R. Jove. 1998. Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol. Cell Biol. 18:2545.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 2545
-
-
Turkson, J.1
Bowman, T.2
Garcia, R.3
Caldenhoven, E.4
De Groot, R.P.5
Jove, R.6
-
11
-
-
0031800697
-
Activation of STAT transcription factors in oncogenic tyrosine kinase signaling
-
Garcia, R., and R. Jove. 1998. Activation of STAT transcription factors in oncogenic tyrosine kinase signaling. J. Biomed. Sci. 5:79.
-
(1998)
J. Biomed. Sci.
, vol.5
, pp. 79
-
-
Garcia, R.1
Jove, R.2
-
12
-
-
0031443156
-
Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells
-
Garcia, R., C. L. Yu, A. Hudnall, R. Catlett, K. L. Nelson, T. Smithgall, D. J. Fujita, S. P. Ethier, and R. Jove. 1997. Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells. Cell Growth Differ. 8:1267.
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 1267
-
-
Garcia, R.1
Yu, C.L.2
Hudnall, A.3
Catlett, R.4
Nelson, K.L.5
Smithgall, T.6
Fujita, D.J.7
Ethier, S.P.8
Jove, R.9
-
13
-
-
0029784886
-
Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines
-
Weber-Nordt, R. M., C. Egen, J. Wehinger, W. Ludwig, V. Gouilleux-Gruart, R. Mertelsmann, and J. Finke. 1996. Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines. Blood 88:809.
-
(1996)
Blood
, vol.88
, pp. 809
-
-
Weber-Nordt, R.M.1
Egen, C.2
Wehinger, J.3
Ludwig, W.4
Gouilleux-Gruart, V.5
Mertelsmann, R.6
Finke, J.7
-
14
-
-
13144276369
-
Proliferation of adult T cell leukemiaflymphoma cells is associated with the constitutive activation of JAK/STAT proteins
-
Takemoto, S., J. C. Mulloy, A. Cereseto, T. S. Migone, B. K. Patel, M. Matsuoka, K. Yamaguchi, K. Takatsuki, S. Kamihira, J. D. White, et al. 1997. Proliferation of adult T cell leukemiaflymphoma cells is associated with the constitutive activation of JAK/STAT proteins. Proc. Natl. Acad. Sci. USA 94:13897.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13897
-
-
Takemoto, S.1
Mulloy, J.C.2
Cereseto, A.3
Migone, T.S.4
Patel, B.K.5
Matsuoka, M.6
Yamaguchi, K.7
Takatsuki, K.8
Kamihira, S.9
White, J.D.10
-
15
-
-
0032984589
-
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
-
Catlett-Falcone, R., T. H. Landowski, M. M. Oshiro, J. Turkson, A. Levitzki, R. Savino. G. Ciliberto, L. Moscinski, J. L. Fernandez-Luna, G. Nunez, et al. 1999. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 10:105.
-
(1999)
Immunity
, vol.10
, pp. 105
-
-
Catlett-Falcone, R.1
Landowski, T.H.2
Oshiro, M.M.3
Turkson, J.4
Levitzki, A.5
Savino, R.6
Ciliberto, G.7
Moscinski, L.8
Fernandez-Luna, J.L.9
Nunez, G.10
-
16
-
-
0031984216
-
BCL-X expression in multiple myeloma: Possible indicator of chemoresistance
-
Tu, Y., S. Renner, F. Xu, A. Fleishman, J. Taylor, J. Weisz, R. Vescio, M. Rettig, J. Berenson, S. Krajewski, et al. 1998. BCL-X expression in multiple myeloma: possible indicator of chemoresistance. Cancer Res. 58:256.
-
(1998)
Cancer Res.
, vol.58
, pp. 256
-
-
Tu, Y.1
Renner, S.2
Xu, F.3
Fleishman, A.4
Taylor, J.5
Weisz, J.6
Vescio, R.7
Rettig, M.8
Berenson, J.9
Krajewski, S.10
-
18
-
-
0026527344
-
Expression of the bcl-2 gene in human multiple myeloma cell lines and normal plasma cells
-
Pettersson, M. H. Jernberg-Wiklund, L. G. Larsson, C. Sundstrom, I. Givol, Y. Tsujimoto, and K. Nilsson. 1992. Expression of the bcl-2 gene in human multiple myeloma cell lines and normal plasma cells. Blood 79:495.
-
(1992)
Blood
, vol.79
, pp. 495
-
-
Pettersson, M.1
Jernberg-Wiklund, H.2
Larsson, L.G.3
Sundstrom, C.4
Givol, I.5
Tsujimoto, Y.6
Nilsson, K.7
-
19
-
-
0029794419
-
Upregulated expression of BCL-2 in multiple myeloma cells induced by exposure to doxorubicin, etoposide, and hydrogen peroxide
-
Tu, Y., F. H. Xu, J. Liu, R. Vescio, J. Berenson, C. Fady, and A. Lichtenstein. 1996. Upregulated expression of BCL-2 in multiple myeloma cells induced by exposure to doxorubicin, etoposide, and hydrogen peroxide. Blood 88:1805.
-
(1996)
Blood
, vol.88
, pp. 1805
-
-
Tu, Y.1
Xu, F.H.2
Liu, J.3
Vescio, R.4
Berenson, J.5
Fady, C.6
Lichtenstein, A.7
-
20
-
-
0037305821
-
Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
-
Bharti, A. C., N. Donato, S. Singh, and B. B. Aggarwal. 2003. Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood 101:1053.
-
(2003)
Blood
, vol.101
, pp. 1053
-
-
Bharti, A.C.1
Donato, N.2
Singh, S.3
Aggarwal, B.B.4
-
21
-
-
0032743140
-
L, NF-κB, and p53
-
L, NF-κB, and p53. Clin. Immunol. 93:152.
-
(1999)
Clin. Immunol.
, vol.93
, pp. 152
-
-
Han, S.S.1
Chung, S.T.2
Robertson, D.A.3
Ranjan, D.4
Bondada, S.5
-
22
-
-
0037069939
-
Circumin-induced suppression of cell proliferation correlates with downregulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation
-
Mukhopadhyay, A., S. Banerjee, L. J. Stafford, X. Xia Chunzhi, M. Liu, and B. B. Aggarwal. Circumin-induced suppression of cell proliferation correlates with downregulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation. Oncogene 21:8852.
-
Oncogene
, vol.21
, pp. 8852
-
-
Mukhopadhyay, A.1
Banerjee, S.2
Stafford, L.J.3
Xia Chunzhi, X.4
Liu, M.5
Aggarwal, B.B.6
-
23
-
-
0030912739
-
Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes
-
Fujio, Y., K. Kunisada. H. Hirota, K. Yamauchi-Takihara, and T. Kishimoto. 1997. Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes. J. Clin. Invest. 99:2898.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2898
-
-
Fujio, Y.1
Kunisada, K.2
Hirota, H.3
Yamauchi-Takihara, K.4
Kishimoto, T.5
-
25
-
-
0014863885
-
Established immunoglobulin producing myeloma (IgE) and lymphoblastoid (IgG) cell lines from an IgE myeloma patient
-
Nilsson, K., H. Bennich, S. G. Johansson, and J. Ponten. 1970. Established immunoglobulin producing myeloma (IgE) and lymphoblastoid (IgG) cell lines from an IgE myeloma patient. Clin. Exp. Immunol. 7:477.
-
(1970)
Clin. Exp. Immunol.
, vol.7
, pp. 477
-
-
Nilsson, K.1
Bennich, H.2
Johansson, S.G.3
Ponten, J.4
-
26
-
-
0024550756
-
Characterization of a novel myeloma cell line
-
Goldman-Leikin, R. E., H. R. Salwen, C. V. Herst, D. Variakojis, M. L. Bian, M. M. Le Beau, P. Selvanayagan, R. Marder, R. Anderson, S. Weitzman, et al. 1989. Characterization of a novel myeloma cell line, MM.1. J. Lab. Clin. Med. 113:335.
-
(1989)
MM.1. J. Lab. Clin. Med.
, vol.113
, pp. 335
-
-
Goldman-Leikin, R.E.1
Salwen, H.R.2
Herst, C.V.3
Variakojis, D.4
Bian, M.L.5
Le Beau, M.M.6
Selvanayagan, P.7
Marder, R.8
Anderson, R.9
Weitzman, S.10
-
27
-
-
0026502886
-
A mechanism of resistance to glucocorticoids in multiple myeloma: Transient expression of a truncated glucocorticoid receptor mRNA
-
Moalli, P. A., S. Pillay, D. Weiner, R. Leikin, and S. T. Rosen. 1992. A mechanism of resistance to glucocorticoids in multiple myeloma: transient expression of a truncated glucocorticoid receptor mRNA. Blood 79:213.
-
(1992)
Blood
, vol.79
, pp. 213
-
-
Moalli, P.A.1
Pillay, S.2
Weiner, D.3
Leikin, R.4
Rosen, S.T.5
-
28
-
-
0032557458
-
Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-κB and activated protein-1
-
Manna, S. K., H. J. Zhang, T, Yan, L. W. Oberley, and B. B. Aggarwal. 1998. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-κB and activated protein-1. J. Biol. Chem. 273:13245.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13245
-
-
Manna, S.K.1
Zhang, H.J.2
Yan, T.3
Oberley, L.W.4
Aggarwal, B.B.5
-
29
-
-
13344295097
-
Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
-
Meydan, N., T. Grunberger, H. Dadi, M. Shahar, E. Arpaia, Z. Lapidot, J. S. Leeder, M. Freedman, A. Cohen, A. Gazit. et al. 1996. Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor. Nature 379:645.
-
(1996)
Nature
, vol.379
, pp. 645
-
-
Meydan, N.1
Grunberger, T.2
Dadi, H.3
Shahar, M.4
Arpaia, E.5
Lapidot, Z.6
Leeder, J.S.7
Freedman, M.8
Cohen, A.9
Gazit, A.10
-
30
-
-
0035977055
-
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation
-
Turkson, J., D. Ryan, J. S. Kim, Y. Zhang, Z. Chen. E. Haura, A. Laudano, S. Sebti, A. D. Hamilton, and R. Jove. 2001. Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation. J. Biol. Chem. 276:45443.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45443
-
-
Turkson, J.1
Ryan, D.2
Kim, J.S.3
Zhang, Y.4
Chen, Z.5
Haura, E.6
Laudano, A.7
Sebti, S.8
Hamilton, A.D.9
Jove, R.10
-
31
-
-
0026062164
-
Characterization of an interleukin-6-mediated autocrine growth loop in the human multiple myeloma cell line, U266
-
Schwab, G., C. B. Siegall, L. A. Aarden, L. M. Neckers, and R. P. Nordan. 1991. Characterization of an interleukin-6-mediated autocrine growth loop in the human multiple myeloma cell line, U266. Blood 77:587.
-
(1991)
Blood
, vol.77
, pp. 587
-
-
Schwab, G.1
Siegall, C.B.2
Aarden, L.A.3
Neckers, L.M.4
Nordan, R.P.5
-
32
-
-
0027980663
-
TNF and IL-6 are potent growth factors for OH-2, a novel human myeloma cell line
-
Borset, M., A. Waage, O. L. Brekke, and E. Helseth. 1994. TNF and IL-6 are potent growth factors for OH-2, a novel human myeloma cell line. Eur. J. Haematol. 53:31.
-
(1994)
Eur. J. Haematol.
, vol.53
, pp. 31
-
-
Borset, M.1
Waage, A.2
Brekke, O.L.3
Helseth, E.4
-
33
-
-
0025274112
-
Autocrine growth by two cytokines, interleukin-6 and tumor necrosis factor α, in the myeloma cell line KHM-IA
-
Hata, H., H. Matsuzaki, and K. Takatsuki. 1990. Autocrine growth by two cytokines, interleukin-6 and tumor necrosis factor α, in the myeloma cell line KHM-IA. Acta Haematol. 83:133.
-
(1990)
Acta Haematol.
, vol.83
, pp. 133
-
-
Hata, H.1
Matsuzaki, H.2
Takatsuki, K.3
-
34
-
-
0024557081
-
Spontaneous secretion of tumor necrosis factor-β by human myeloma cell lines
-
Bataille, R., B. Klein, M. Jourdan, J. F. Rossi, and B. G. Durie. 1989. Spontaneous secretion of tumor necrosis factor-β by human myeloma cell lines. Cancer 63:877.
-
(1989)
Cancer
, vol.63
, pp. 877
-
-
Bataille, R.1
Klein, B.2
Jourdan, M.3
Rossi, J.F.4
Durie, B.G.5
-
35
-
-
0023227925
-
Production of lymphotoxin, a bone-resorbing cytokine, by cultured human myeloma cells
-
Garrett, I. R., B. G. Durie, G. E. Nedwin, A. Gillespie, T. Bringman, M. Sabatini, D. R. Bertolini, and G. R. Mundy. 1987. Production of lymphotoxin, a bone-resorbing cytokine, by cultured human myeloma cells. N. Engl. J. Med. 317:526.
-
(1987)
N. Engl. J. Med.
, vol.317
, pp. 526
-
-
Garrett, I.R.1
Durie, B.G.2
Nedwin, G.E.3
Gillespie, A.4
Bringman, T.5
Sabatini, M.6
Bertolini, D.R.7
Mundy, G.R.8
-
36
-
-
0036148801
-
Tumor necrosis factor α (TNF-α) activates Jak1/Stat3-Stat5B signaling through TNFR-1 in human B cells
-
Miscia, S., M. Marchisio, A. Grilli, V. Di Valerio, L. Centurione, G. Sabatino, F. Garaci, G. Zauli, E. Bonvini, and A. Di Baldassarre. 2002. Tumor necrosis factor α (TNF-α) activates Jak1/Stat3-Stat5B signaling through TNFR-1 in human B cells. Cell Growth Differ. 13:13.
-
(2002)
Cell Growth Differ.
, vol.13
, pp. 13
-
-
Miscia, S.1
Marchisio, M.2
Grilli, A.3
Di Valerio, V.4
Centurione, L.5
Sabatino, G.6
Garaci, F.7
Zauli, G.8
Bonvini, E.9
Di Baldassarre, A.10
-
37
-
-
0032521284
-
Induction of Jak/STAT signaling by activation of the type 1 TNF receptor
-
Guo, D., J. D. Dunbar, C. H. Yang, L. M. Pfeffer, and D. B. Donner. 1998. Induction of Jak/STAT signaling by activation of the type 1 TNF receptor. J. Immunol. 160:2742.
-
(1998)
J. Immunol.
, vol.160
, pp. 2742
-
-
Guo, D.1
Dunbar, J.D.2
Yang, C.H.3
Pfeffer, L.M.4
Donner, D.B.5
-
38
-
-
0028920301
-
Effect of IL-6 receptor antisense oligodeoxynucleotide on in vitro proliferation of myeloma cells
-
Keller, E. T., and W. B. Ershler. 1995. Effect of IL-6 receptor antisense oligodeoxynucleotide on in vitro proliferation of myeloma cells. J. Immunol. 154:4091.
-
(1995)
J. Immunol.
, vol.154
, pp. 4091
-
-
Keller, E.T.1
Ershler, W.B.2
-
39
-
-
0037097660
-
Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes
-
Natarajan, C., and J. J. Bright. 2002. Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes. J. Immunol. 168:6506.
-
(2002)
J. Immunol.
, vol.168
, pp. 6506
-
-
Natarajan, C.1
Bright, J.J.2
-
40
-
-
0035284754
-
Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway
-
Li, W. Q., F. Dehnade, and M. Zafarullah. 2001. Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway. J. Immunol. 166: 3491.
-
(2001)
J. Immunol.
, vol.166
, pp. 3491
-
-
Li, W.Q.1
Dehnade, F.2
Zafarullah, M.3
-
41
-
-
0037015683
-
IL-6 mediated activation of STAT3 bypasses Janus kinases in terminally differentiated B lineage cells
-
Kopantzev, Y., M. Heller, N. Swaminathan, and S. Rudikoff. 2002. IL-6 mediated activation of STAT3 bypasses Janus kinases in terminally differentiated B lineage cells. Oncogene 21:6791.
-
(2002)
Oncogene
, vol.21
, pp. 6791
-
-
Kopantzev, Y.1
Heller, M.2
Swaminathan, N.3
Rudikoff, S.4
-
42
-
-
0037160057
-
Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain
-
Schreiner, S. J., A. P. Schiavone, and T. E. Smithgall. 2002. Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain. J. Biol. Chem. 277:45680.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45680
-
-
Schreiner, S.J.1
Schiavone, A.P.2
Smithgall, T.E.3
-
43
-
-
0037064121
-
ErbB-2 activates Stat3 α in a Src- and JAK2-dependent manner
-
Ren, Z., and T. S. Schaefer. 2002. ErbB-2 activates Stat3 α in a Src- and JAK2-dependent manner. J. Biol. Chem. 277:38486.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38486
-
-
Ren, Z.1
Schaefer, T.S.2
-
44
-
-
85047699293
-
Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death
-
Zamo, A., R. Chiarle, R. Piva, J. Howes, Y. Fan, M. Chilosi, D. E. Levy, and G. Inghirami. 2002. Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death. Oncogene 21:1038.
-
(2002)
Oncogene
, vol.21
, pp. 1038
-
-
Zamo, A.1
Chiarle, R.2
Piva, R.3
Howes, J.4
Fan, Y.5
Chilosi, M.6
Levy, D.E.7
Inghirami, G.8
-
45
-
-
0035799531
-
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
-
Garcia, R., T. L. Bowman, G. Niu, H. Yu, S. Minton, C. A. Muro-Cacho, C. E. Cox, R. Falcone, R. Fairclough, S. Parsons, et al. 2001. Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene 20:2499.
-
(2001)
Oncogene
, vol.20
, pp. 2499
-
-
Garcia, R.1
Bowman, T.L.2
Niu, G.3
Yu, H.4
Minton, S.5
Muro-Cacho, C.A.6
Cox, C.E.7
Falcone, R.8
Fairclough, R.9
Parsons, S.10
-
46
-
-
0034637540
-
Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity
-
Zhang, Y., J. Turkson, C. Carter-Su, T. Smithgall, A. Levitzki, A. Kraker, J. J. Krolewski, P. Medveczky, and R. Jove. 2000. Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity. J. Biol. Chem. 275:24935.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 24935
-
-
Zhang, Y.1
Turkson, J.2
Carter-Su, C.3
Smithgall, T.4
Levitzki, A.5
Kraker, A.6
Krolewski, J.J.7
Medveczky, P.8
Jove, R.9
-
47
-
-
0034685906
-
Mechanism of STAT3 activation by insulin-like growth factor I receptor
-
Zong, C. S., J. Chan, D. E. Levy, C. Horvath, H. B. Sadowski, and L. H. Wang. 2000. Mechanism of STAT3 activation by insulin-like growth factor I receptor. J. Biol. Chem. 275:15099.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 15099
-
-
Zong, C.S.1
Chan, J.2
Levy, D.E.3
Horvath, C.4
Sadowski, H.B.5
Wang, L.H.6
-
48
-
-
0034690026
-
Activation of Stat3 preassembled with platelet-derived growth factor β receptors requires Src kinase activity
-
Wang, Y. Z., W. Wharton, R. Garcia, A. Kraker, R. Jove, and W. J. Pledger. 2000. Activation of Stat3 preassembled with platelet-derived growth factor β receptors requires Src kinase activity. Oncogene 19:2075.
-
(2000)
Oncogene
, vol.19
, pp. 2075
-
-
Wang, Y.Z.1
Wharton, W.2
Garcia, R.3
Kraker, A.4
Jove, R.5
Pledger, W.J.6
-
49
-
-
0033588229
-
Protein kinase Cδ associates with and phosphorylates Stat3 in an interleukin-6-dependent manner
-
Jain, N., T. Zhang, W. H. Kee, W. Li, and X. Cao. 1999. Protein kinase Cδ associates with and phosphorylates Stat3 in an interleukin-6-dependent manner. J. Biol. Chem. 274:24392.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 24392
-
-
Jain, N.1
Zhang, T.2
Kee, W.H.3
Li, W.4
Cao, X.5
-
50
-
-
0033522985
-
Activated G protein-coupled receptor induces tyrosine phosphorylation of STAT3 and agonist-selective serine phosphorylation via sustained stimulation of mitogen-activated protein kinase: Resultant effects on cell proliferation
-
Sellers, L. A., W. Feniuk, P. P. Humphrey, and H. Lauder. 1999. Activated G protein-coupled receptor induces tyrosine phosphorylation of STAT3 and agonist-selective serine phosphorylation via sustained stimulation of mitogen-activated protein kinase: resultant effects on cell proliferation. J. Biol. Chem. 274:16423.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16423
-
-
Sellers, L.A.1
Feniuk, W.2
Humphrey, P.P.3
Lauder, H.4
-
51
-
-
0031742128
-
Activation of Stat3 by v-Src is through a Ras-independent pathway
-
Liu, J. J., K. Nakajima, T. Hirano, and H. F. Yang-Yen. 1998. Activation of Stat3 by v-Src is through a Ras-independent pathway. J. Biomed. Sci. 5:446.
-
(1998)
J. Biomed. Sci.
, vol.5
, pp. 446
-
-
Liu, J.J.1
Nakajima, K.2
Hirano, T.3
Yang-Yen, H.F.4
-
52
-
-
0032479519
-
c-Fes tyrosine kinase binds to and activates STAT3 after granulocyte-macrophage colony-stimulating factor stimulation
-
Park, W. Y., J. H. Ahn, R. A. Feldman, and J. S. Seo. 1998. c-Fes tyrosine kinase binds to and activates STAT3 after granulocyte-macrophage colony-stimulating factor stimulation. Cancer Lett. 129:29.
-
(1998)
Cancer Lett.
, vol.129
, pp. 29
-
-
Park, W.Y.1
Ahn, J.H.2
Feldman, R.A.3
Seo, J.S.4
-
53
-
-
0032473935
-
Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation
-
Chaturvedi, P., M. V. Reddy, and E. P. Reddy. 1998. Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation. Oncogene 16:1749.
-
(1998)
Oncogene
, vol.16
, pp. 1749
-
-
Chaturvedi, P.1
Reddy, M.V.2
Reddy, E.P.3
-
54
-
-
0030447148
-
In vitro activation of Stat3 by epidermal growth factor receptor kinase
-
Park, O. K., T. S. Schaefer, and D. Nathans. 1996. In vitro activation of Stat3 by epidermal growth factor receptor kinase. Proc. Natl. Acad. Sci. USA 93:13704.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13704
-
-
Park, O.K.1
Schaefer, T.S.2
Nathans, D.3
-
55
-
-
0032549676
-
Activation of STAT3 by the c-Fes protein-tyrosine kinase
-
Nelson, K. L., J. A. Rogers, T. L. Bowman, R. Jove, and T. E. Smithgall. 1998. Activation of STAT3 by the c-Fes protein-tyrosine kinase. J. Biol. Chem. 273:7072.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7072
-
-
Nelson, K.L.1
Rogers, J.A.2
Bowman, T.L.3
Jove, R.4
Smithgall, T.E.5
-
56
-
-
0033861096
-
JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells
-
De Vos, J., M. Jourdan, K. Tarte, C. Jasmin, and B. Klein. 2000. JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells. Br. J. Haematol. 109:823.
-
(2000)
Br. J. Haematol.
, vol.109
, pp. 823
-
-
De Vos, J.1
Jourdan, M.2
Tarte, K.3
Jasmin, C.4
Klein, B.5
-
57
-
-
0028220931
-
Curcumin is a non-competitive and selective inhibitor of phosphorylase kinase
-
Reddy, S., and B. B. Aggarwal. 1994. Curcumin is a non-competitive and selective inhibitor of phosphorylase kinase. FEBS Lett. 341:19.
-
(1994)
FEBS Lett.
, vol.341
, pp. 19
-
-
Reddy, S.1
Aggarwal, B.B.2
-
59
-
-
0028556758
-
Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells
-
Korutla, L., and R. Kumar. 1994. Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells. Biochim. Biophys. Acta 1224:597.
-
(1994)
Biochim. Biophys. Acta
, vol.1224
, pp. 597
-
-
Korutla, L.1
Kumar, R.2
-
60
-
-
0029069540
-
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
-
Yu, C. L., D. J. Meyer, G. S. Campbell, A. C. Larner, C. Carter-Su, J. Schwartz, and R. Jove. 1995. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 269:81.
-
(1995)
Science
, vol.269
, pp. 81
-
-
Yu, C.L.1
Meyer, D.J.2
Campbell, G.S.3
Larner, A.C.4
Carter-Su, C.5
Schwartz, J.6
Jove, R.7
-
61
-
-
0034658698
-
STATs in oncogenesis
-
Bowman, T., R. Garcia, J. Turkson, and R. Jove. 2000. STATs in oncogenesis. Oncogene 19:2474.
-
(2000)
Oncogene
, vol.19
, pp. 2474
-
-
Bowman, T.1
Garcia, R.2
Turkson, J.3
Jove, R.4
-
62
-
-
0033529704
-
Stat3 as an oncogene
-
Bromberg, J. F., M. H. Wrzeszczynska, G. Devgan, Y. Zhao, R. G. Pestell, C. Albanese, and J. E. Darnell. Jr. 1999. Stat3 as an oncogene. Cell 98:295.
-
(1999)
Cell
, vol.98
, pp. 295
-
-
Bromberg, J.F.1
Wrzeszczynska, M.H.2
Devgan, G.3
Zhao, Y.4
Pestell, R.G.5
Albanese C., Jr.6
Darnell, J.E.7
-
63
-
-
0032213273
-
Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: Generation and characterization of T cell-specific Stat3-deficient mice
-
Takeda, K., T. Kaisho, N. Yoshida, J. Takeda, T. Kishimoto, and S. Akira. 1998. Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J. Immunol. 161:4652.
-
(1998)
J. Immunol.
, vol.161
, pp. 4652
-
-
Takeda, K.1
Kaisho, T.2
Yoshida, N.3
Takeda, J.4
Kishimoto, T.5
Akira, S.6
-
64
-
-
0035852765
-
Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1
-
Shen, Y., G. Devgan, J. E. Darnell, Jr., and J. F. Bromberg. 2001. Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1. Proc. Natl. Acad. Sci. USA 98:1543.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1543
-
-
Shen, Y.1
Devgan, G.2
Darnell J.E., Jr.3
Bromberg, J.F.4
-
65
-
-
0034658499
-
STAT signaling in head and neck cancer
-
Song, J. I., and J. R. Grandis. 2000. STAT signaling in head and neck cancer. Oncogene 19:2489.
-
(2000)
Oncogene
, vol.19
, pp. 2489
-
-
Song, J.I.1
Grandis, J.R.2
-
66
-
-
0035042611
-
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
-
Yoshikawa, H., K. Matsubara, G. S. Qian, P. Jackson, J. D. Groopman, J. E. Manning, C. C. Harris, and J. G. Herman. 2001. SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity. Nat. Genet. 28:29.
-
(2001)
Nat. Genet.
, vol.28
, pp. 29
-
-
Yoshikawa, H.1
Matsubara, K.2
Qian, G.S.3
Jackson, P.4
Groopman, J.D.5
Manning, J.E.6
Harris, C.C.7
Herman, J.G.8
-
67
-
-
0036134884
-
Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma
-
Zhang, Q., P. N. Raghunath, L. Xue, M. Majewski, D. F. Carpentieri, N. Odum, S. Morris, T. Skorski, and M. A. Wasik. 2002. Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma. J. Immunol. 168:466.
-
(2002)
J. Immunol.
, vol.168
, pp. 466
-
-
Zhang, Q.1
Raghunath, P.N.2
Xue, L.3
Majewski, M.4
Carpentieri, D.F.5
Odum, N.6
Morris, S.7
Skorski, T.8
Wasik, M.A.9
-
68
-
-
0038784365
-
SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma
-
Galm, O., H. Yoshikawa, M. Esteller, R. Osieka, and J. G. Herman. 2003. SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma. Blood 101:2784.
-
(2003)
Blood
, vol.101
, pp. 2784
-
-
Galm, O.1
Yoshikawa, H.2
Esteller, M.3
Osieka, R.4
Herman, J.G.5
-
69
-
-
0033817448
-
Role of curcumin in idiopathic inflammatory orbital pseudotumours
-
Lal, B., A. K. Kapoor, P. K. Agrawal, O. P. Asthana, and R. C. Srimal. 2000. Role of curcumin in idiopathic inflammatory orbital pseudotumours. Phytother. Res. 14:443.
-
(2000)
Phytother. Res.
, vol.14
, pp. 443
-
-
Lal, B.1
Kapoor, A.K.2
Agrawal, P.K.3
Asthana, O.P.4
Srimal, R.C.5
-
70
-
-
0033062493
-
Efficacy of curcumin in the management of chronic anterior uveitis
-
Lal, B., A. K. Kapoor, O. P. Asthana, P. K. Agrawal, R. Prasad, P. Kumar, and R. C. Srimal. 1999. Efficacy of curcumin in the management of chronic anterior uveitis. Phytother. Res. 13:318.
-
(1999)
Phytother. Res.
, vol.13
, pp. 318
-
-
Lal, B.1
Kapoor, A.K.2
Asthana, O.P.3
Agrawal, P.K.4
Prasad, R.5
Kumar, P.6
Srimal, R.C.7
-
71
-
-
0035667365
-
Clinical development of leukocyte cyclooxygenase 2 activity as a systemic biomarker for cancer chemopreventive agents
-
Plummer, S. M., K. A. Hill, M. F. Festing, W. P. Steward, A. J. Gescher, and R. A. Sharma. 2001. Clinical development of leukocyte cyclooxygenase 2 activity as a systemic biomarker for cancer chemopreventive agents. Cancer Epidemiol. Biomarkers Prev. 10:1295.
-
(2001)
Cancer Epidemiol. Biomarkers Prev.
, vol.10
, pp. 1295
-
-
Plummer, S.M.1
Hill, K.A.2
Festing, M.F.3
Steward, W.P.4
Gescher, A.J.5
Sharma, R.A.6
-
72
-
-
0035174504
-
Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk of pre-malignant lesions
-
Cheng, A. L., C. H. Hsu, J. K. Lin, M. M. Hsu, Y. F. Ho, T. S. Shen, J, Y. Ko, J. T. Lin, B. R. Lin, W. Ming-Shiang, et al. 2001. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk of pre-malignant lesions. Anticancer Res. 21:2895.
-
(2001)
Anticancer Res.
, vol.21
, pp. 2895
-
-
Cheng, A.L.1
Hsu, C.H.2
Lin, J.K.3
Hsu, M.M.4
Ho, Y.F.5
Shen, T.S.6
Ko, J.Y.7
Lin, J.T.8
Lin, B.R.9
Ming-Shiang, W.10
-
73
-
-
0034772953
-
Pharmacodynamic and pharmacokinetic study of oral curcuma extract in patients with colorectal cancer
-
Sharma. R. A., H. R. McLelland, K, A. Hill, C. R. Ireson, S. A. Euden, M. M. Manson, M. Pirmohamed, L. J. Marnett, A, J. Gescher, and W. P. Steward. 2001. Pharmacodynamic and pharmacokinetic study of oral curcuma extract in patients with colorectal cancer. Clin. Cancer Res. 7:1894.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1894
-
-
Sharma, R.A.1
McLelland, H.R.2
Hill, K.A.3
Ireson, C.R.4
Euden, S.A.5
Manson, M.M.6
Pirmohamed, M.7
Marnett, L.J.8
Gescher, A.J.9
Steward, W.P.10
|