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Volumn 181, Issue 1, 2009, Pages 77-84

[6]-Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells

Author keywords

6 Gingerol; A431 cells; Anti cancer activities; Apoptosis; HPLC; Skin cancer

Indexed keywords

(6) GINGEROL; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE;

EID: 67650651898     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.05.012     Document Type: Article
Times cited : (81)

References (27)
  • 1
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • Aggarwal B.B., and Shishodia S. Molecular targets of dietary agents for prevention and therapy of cancer. Biochem. Pharmacol. 71 (2006) 1397-1421
    • (2006) Biochem. Pharmacol. , vol.71 , pp. 1397-1421
    • Aggarwal, B.B.1    Shishodia, S.2
  • 3
    • 34047135039 scopus 로고    scopus 로고
    • [6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo
    • Kim J.K., Kim Y., Na K.M., Surh Y.J., and Kim T.Y. [6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo. Free Radic. Res. 41 (2007) 603-614
    • (2007) Free Radic. Res. , vol.41 , pp. 603-614
    • Kim, J.K.1    Kim, Y.2    Na, K.M.3    Surh, Y.J.4    Kim, T.Y.5
  • 4
    • 33750685296 scopus 로고    scopus 로고
    • [6]-Gingerol induces cell cycle arrest and cell death of mutant p53-expressing pancreatic cancer cells
    • Park Y.J., Wen J., Bang S., Park S.W., and Song S.Y. [6]-Gingerol induces cell cycle arrest and cell death of mutant p53-expressing pancreatic cancer cells. Yonsei Med. J. 47 (2006) 688-697
    • (2006) Yonsei Med. J. , vol.47 , pp. 688-697
    • Park, Y.J.1    Wen, J.2    Bang, S.3    Park, S.W.4    Song, S.Y.5
  • 5
    • 17844362777 scopus 로고    scopus 로고
    • [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin
    • Kim S.O., Kundu J.K., Shin Y.K., Park J.H., Cho M.H., Kim T.Y., and Surh Y.J. [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin. Oncogene 24 (2005) 2558-2567
    • (2005) Oncogene , vol.24 , pp. 2558-2567
    • Kim, S.O.1    Kundu, J.K.2    Shin, Y.K.3    Park, J.H.4    Cho, M.H.5    Kim, T.Y.6    Surh, Y.J.7
  • 6
    • 26444560222 scopus 로고    scopus 로고
    • Induction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF-beta1 involves MAPK, Smad and AP-1 signalling pathways
    • Davies M., Robinson M., Smith E., Huntley S., Prime S., and Paterson I. Induction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF-beta1 involves MAPK, Smad and AP-1 signalling pathways. J. Cell Biochem. 95 (2005) 918-931
    • (2005) J. Cell Biochem. , vol.95 , pp. 918-931
    • Davies, M.1    Robinson, M.2    Smith, E.3    Huntley, S.4    Prime, S.5    Paterson, I.6
  • 7
    • 0035110888 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6]-gingerol
    • Bode A.M., Ma W.Y., Surh Y.J., and Dong Z. Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6]-gingerol. Cancer Res. 61 (2001) 850-853
    • (2001) Cancer Res. , vol.61 , pp. 850-853
    • Bode, A.M.1    Ma, W.Y.2    Surh, Y.J.3    Dong, Z.4
  • 8
    • 38049068003 scopus 로고    scopus 로고
    • In vitro and in vivo modulation of testosterone mediated alterations in apoptosis related proteins by [6]-gingerol
    • Shukla Y., Prasad S., Tripathi C., Singh M., George J., and Kalra N. In vitro and in vivo modulation of testosterone mediated alterations in apoptosis related proteins by [6]-gingerol. Mol. Nutr. Food Res. 51 (2007) 1492-1502
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 1492-1502
    • Shukla, Y.1    Prasad, S.2    Tripathi, C.3    Singh, M.4    George, J.5    Kalra, N.6
  • 9
    • 12844250848 scopus 로고    scopus 로고
    • Modulation of P-glycoprotein-mediated multidrug resistance in K562 leukemic cells by indole-3-carbinol
    • Arora A., Seth K., Kalra N., and Shukla Y. Modulation of P-glycoprotein-mediated multidrug resistance in K562 leukemic cells by indole-3-carbinol. Toxicol. Appl. Pharmacol. 202 (2005) 237-243
    • (2005) Toxicol. Appl. Pharmacol. , vol.202 , pp. 237-243
    • Arora, A.1    Seth, K.2    Kalra, N.3    Shukla, Y.4
  • 10
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I., Migliorati G., Pagliacci M.C., Grignani F., and Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139 (1991) 271-279
    • (1991) J. Immunol. Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 11
    • 0032479460 scopus 로고    scopus 로고
    • Mitochondria and cells produce reactive oxygen species in virtual anaerobiosis: relevance to ceramide-induced apoptosis
    • Esposti D.M., and McLennan H. Mitochondria and cells produce reactive oxygen species in virtual anaerobiosis: relevance to ceramide-induced apoptosis. FEBS Lett. 430 (1998) 338-342
    • (1998) FEBS Lett. , vol.430 , pp. 338-342
    • Esposti, D.M.1    McLennan, H.2
  • 12
    • 0345120940 scopus 로고    scopus 로고
    • Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives
    • Scaduto Jr. R.C., and Grotyohann L.W. Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives. Biophys. J. 76 (1999) 469-477
    • (1999) Biophys. J. , vol.76 , pp. 469-477
    • Scaduto Jr., R.C.1    Grotyohann, L.W.2
  • 13
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller S.A., Dykes D.D., and Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16 (1988) 1215
    • (1988) Nucleic Acids Res. , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 14
    • 33749241471 scopus 로고    scopus 로고
    • Regulation of p21/ras protein expression by diallyl sulfide in DMBA induced neoplastic changes in mouse skin
    • Arora A., Kalra N., and Shukla Y. Regulation of p21/ras protein expression by diallyl sulfide in DMBA induced neoplastic changes in mouse skin. Cancer Lett. 242 (2006) 28-36
    • (2006) Cancer Lett. , vol.242 , pp. 28-36
    • Arora, A.1    Kalra, N.2    Shukla, Y.3
  • 15
    • 22544442768 scopus 로고    scopus 로고
    • Gingerol content of diploid and tetraploid clones of ginger (Zingiber officinale roscoe)
    • Wohlmuth H., Leach D.N., Smith M.K., and Myers S.P. Gingerol content of diploid and tetraploid clones of ginger (Zingiber officinale roscoe). J. Agric. Food Chem. 53 (2005) 5772-5778
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 5772-5778
    • Wohlmuth, H.1    Leach, D.N.2    Smith, M.K.3    Myers, S.P.4
  • 16
    • 0022438530 scopus 로고
    • Mitochondrial analysis in living cells: the use of rhodamine 123 and flow cytometry
    • Ronot X., Benel L., Adolphe M., and Mounolou J.C. Mitochondrial analysis in living cells: the use of rhodamine 123 and flow cytometry. Biol. Cell. 57 (1986) 1-7
    • (1986) Biol. Cell. , vol.57 , pp. 1-7
    • Ronot, X.1    Benel, L.2    Adolphe, M.3    Mounolou, J.C.4
  • 17
    • 0038621801 scopus 로고    scopus 로고
    • Reactive oxygen species and UV-B: effect on cyanobacteria
    • He Y.Y., and Häder D. Reactive oxygen species and UV-B: effect on cyanobacteria. Photochem. Photobiol. Sci. 1 (2002) 729-736
    • (2002) Photochem. Photobiol. Sci. , vol.1 , pp. 729-736
    • He, Y.Y.1    Häder, D.2
  • 18
    • 0032547010 scopus 로고    scopus 로고
    • Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice
    • Park K.K., Chun K.S., Lee J.M., Lee S.S., and Surh Y.J. Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice. Cancer Lett. 129 (1998) 139-144
    • (1998) Cancer Lett. , vol.129 , pp. 139-144
    • Park, K.K.1    Chun, K.S.2    Lee, J.M.3    Lee, S.S.4    Surh, Y.J.5
  • 19
    • 40749083585 scopus 로고    scopus 로고
    • Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells
    • Lee S.H., Cekanova M., and Baek S.J. Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells. Mol. Carcinog. 47 (2008) 197-208
    • (2008) Mol. Carcinog. , vol.47 , pp. 197-208
    • Lee, S.H.1    Cekanova, M.2    Baek, S.J.3
  • 20
    • 34247473885 scopus 로고    scopus 로고
    • In vitro evaluation of the anticancer effect of lactoferrin and tea polyphenol combination on oral carcinoma cells
    • Mohan K.V., Gunasekaran P., Varalakshmi E., Hara Y., and Nagini S. In vitro evaluation of the anticancer effect of lactoferrin and tea polyphenol combination on oral carcinoma cells. Cell Biol. Int. 31 (2007) 599-608
    • (2007) Cell Biol. Int. , vol.31 , pp. 599-608
    • Mohan, K.V.1    Gunasekaran, P.2    Varalakshmi, E.3    Hara, Y.4    Nagini, S.5
  • 21
    • 0037441392 scopus 로고    scopus 로고
    • Molecular ordering of ROS production, mitochondrial changes, and caspase activation during sodium salicylate-induced apoptosis
    • Chung Y.M., Bae Y.S., and Lee S.Y. Molecular ordering of ROS production, mitochondrial changes, and caspase activation during sodium salicylate-induced apoptosis. Free Radic. Biol. Med. 34 (2003) 434-442
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 434-442
    • Chung, Y.M.1    Bae, Y.S.2    Lee, S.Y.3
  • 23
    • 36348934636 scopus 로고    scopus 로고
    • Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic Bcl-2 family members
    • Chen M., Guerrero A.D., Huang L., Shabier Z., Pan M., Tan T.H., and Wang J. Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic Bcl-2 family members. J. Biol. Chem. 282 (2007) 33888-33895
    • (2007) J. Biol. Chem. , vol.282 , pp. 33888-33895
    • Chen, M.1    Guerrero, A.D.2    Huang, L.3    Shabier, Z.4    Pan, M.5    Tan, T.H.6    Wang, J.7
  • 25
    • 34247159678 scopus 로고    scopus 로고
    • Grape seed proanthocyanidins promote apoptosis in human epidermoid carcinoma A431 cells through alterations in Cdki-Cdk-cyclin cascade, and caspase-3 activation via loss of mitochondrial membrane potential
    • Meeran S.M., and Katiyar S.K. Grape seed proanthocyanidins promote apoptosis in human epidermoid carcinoma A431 cells through alterations in Cdki-Cdk-cyclin cascade, and caspase-3 activation via loss of mitochondrial membrane potential. Exp. Dermatol. 16 (2007) 405-415
    • (2007) Exp. Dermatol. , vol.16 , pp. 405-415
    • Meeran, S.M.1    Katiyar, S.K.2
  • 26
    • 33745627338 scopus 로고    scopus 로고
    • Variation in concentration and labeling of ginger root. Dietary supplements
    • Schwertner H.A., Rios D.C., and Pascoe J.E. Variation in concentration and labeling of ginger root. Dietary supplements. Obstet. Gynecol. 107 (2006) 1337-1343
    • (2006) Obstet. Gynecol. , vol.107 , pp. 1337-1343
    • Schwertner, H.A.1    Rios, D.C.2    Pascoe, J.E.3
  • 27
    • 57649102485 scopus 로고    scopus 로고
    • Novel Ras pathway inhibitor induces apoptosis and growth inhibition of K-ras-mutated cancer cells in vitro and in vivo
    • Jasinski P., Zwolak P., Terai K., and Dudek A.Z. Novel Ras pathway inhibitor induces apoptosis and growth inhibition of K-ras-mutated cancer cells in vitro and in vivo. Transl. Res. 152 (2008) 203-212
    • (2008) Transl. Res. , vol.152 , pp. 203-212
    • Jasinski, P.1    Zwolak, P.2    Terai, K.3    Dudek, A.Z.4


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