[6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin

Oncogene

Volumn 24, Issue 15, 2005, Pages 2558-2567

  Kim, Sue Ok ^a   Kundu, Joydeb Kumar ^a   Shin, Young Kee ^a   Park, Jin Hong ^a   Cho, Myung Haing ^a   Kim, Tae Yoon ^b   Surh, Young Joon ^a  

^a Seoul National University   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

Chemoprevention; Cyclooxygenase 2 6 gingerol; Mouse skin; NF B; P38 MAPK

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYCLOOXYGENASE 2; GINGEROL; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR; TUMOR PROMOTER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; GINGER; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SKIN STIMULATION; TRANSCRIPTION REGULATION; UPREGULATION;

ANIMALS; CHEMOPREVENTION; CYCLOOXYGENASE 2; ENZYME ACTIVATION; FATTY ALCOHOLS; FEMALE; MICE; MICE, INBRED ICR; MUTAGENS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHORBOL ESTERS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SKIN; SKIN NEOPLASMS;

EID: 17844362777     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208446     Document Type: Article

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